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1دورية أكاديمية
المؤلفون: Ng NHJ; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore., Ghosh S; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore., Bok CM; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore., Ching C; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore., Low BSJ; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore., Chen JT; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore.; Department of Biochemistry, National University of Singapore, Singapore, 117596, Singapore., Lim E; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.; Department of Biochemistry, National University of Singapore, Singapore, 117596, Singapore., Miserendino MC; Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, X5000HUA, Córdoba, Argentina.; Bioinformatics Institute, A*STAR, Singapore, 138671, Singapore., Tan YS; Bioinformatics Institute, A*STAR, Singapore, 138671, Singapore., Hoon S; Molecular Engineering Laboratory, IMCB, A*STAR, Singapore, 138673, Singapore., Teo AKK; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore. ateo@imcb.a-star.edu.sg.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore. ateo@imcb.a-star.edu.sg.; Department of Biochemistry, National University of Singapore, Singapore, 117596, Singapore. ateo@imcb.a-star.edu.sg.; Precision Medicine Translational Research Programme (TRP), National University of Singapore, Singapore, 119228, Singapore. ateo@imcb.a-star.edu.sg.
المصدر: Nature communications [Nat Commun] 2024 Jun 22; Vol. 15 (1), pp. 4288. Date of Electronic Publication: 2024 Jun 22.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
مواضيع طبية MeSH: Hepatocyte Nuclear Factor 4*/metabolism , Hepatocyte Nuclear Factor 4*/genetics , Hepatocyte Nuclear Factor 1-alpha*/metabolism , Hepatocyte Nuclear Factor 1-alpha*/genetics , Insulin-Secreting Cells*/metabolism , Diabetes Mellitus, Type 2*/genetics , Diabetes Mellitus, Type 2*/metabolism , Hepatocytes*/metabolism , Gene Expression Regulation*, Humans ; Animals ; Mice ; A Kinase Anchor Proteins/metabolism ; A Kinase Anchor Proteins/genetics ; Organ Specificity/genetics
SCR Disease Name: Mason-Type Diabetes
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2دورية أكاديمية
المؤلفون: Low BSJ; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lim CS; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore., Ding SSL; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Tan YS; Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Ng NHJ; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Krishnan VG; Molecular Engineering Lab (MEL), IMCB, A*STAR, Singapore, Singapore., Ang SF; Khoo Teck Puat Hospital, Singapore, Singapore., Neo CWY; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Verma CS; Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Department of Biological Sciences, National University of Singapore, Singapore, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Hoon S; Molecular Engineering Lab (MEL), IMCB, A*STAR, Singapore, Singapore., Lim SC; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Khoo Teck Puat Hospital, Singapore, Singapore., Tai ES; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Teo AKK; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. ateo@imcb.a-star.edu.sg.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. ateo@imcb.a-star.edu.sg.
المصدر: Nature communications [Nat Commun] 2021 May 25; Vol. 12 (1), pp. 3133. Date of Electronic Publication: 2021 May 25.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
مواضيع طبية MeSH: Mutation*, Diabetes Mellitus, Type 2/*genetics , Glucose/*metabolism , Glucose Transporter Type 2/*genetics , Hepatocyte Nuclear Factor 1-alpha/*genetics , Insulin Secretion/*genetics , Insulin-Secreting Cells/*metabolism, Cells, Cultured ; Chromatin Immunoprecipitation Sequencing/methods ; Diabetes Mellitus, Type 2/metabolism ; Female ; Glucose Transporter Type 2/metabolism ; Hepatocyte Nuclear Factor 1-alpha/chemistry ; Hepatocyte Nuclear Factor 1-alpha/metabolism ; Humans ; Induced Pluripotent Stem Cells/cytology ; Induced Pluripotent Stem Cells/metabolism ; Insulin-Secreting Cells/cytology ; Male ; Molecular Dynamics Simulation ; Pedigree ; Protein Domains
SCR Disease Name: Mason-Type Diabetes
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3دورية أكاديمية
المؤلفون: Amirruddin NS; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), A*STAR, Proteos, Singapore, 138673, Singapore; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore., Low BSJ; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), A*STAR, Proteos, Singapore, 138673, Singapore; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore., Lee KO; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore., Tai ES; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore. Electronic address: mdctes@nus.edu.sg., Teo AKK; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), A*STAR, Proteos, Singapore, 138673, Singapore; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore. Electronic address: ateo@imcb.a-star.edu.sg.
المصدر: Seminars in cell & developmental biology [Semin Cell Dev Biol] 2020 Jul; Vol. 103, pp. 31-40. Date of Electronic Publication: 2019 Nov 19.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review
بيانات الدورية: Publisher: Academic Press Country of Publication: England NLM ID: 9607332 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-3634 (Electronic) Linking ISSN: 10849521 NLM ISO Abbreviation: Semin Cell Dev Biol Subsets: MEDLINE
مواضيع طبية MeSH: Cell Biology/*standards , Diabetes Mellitus/*metabolism , Induced Pluripotent Stem Cells/*metabolism, Cell Differentiation ; Humans