المؤلفون: Cook, Lola, Verbrugge, Jennifer, Schwantes-An, Tae-Hwi, Schulze, Jeanine, Foroud, Tatiana, Hall, Anne, Marder, Karen, Mata, Ignacio, Mencacci, Niccolò, Nance, Martha, Schwarzschild, Michael, Simuni, Tanya, Bressman, Susan, Wills, Anne-Marie, Fernandez, Hubert, Litvan, Irene, Lyons, Kelly, Shill, Holly, Singer, Carlos, Tropea, Thomas, Vanegas Arroyave, Nora, Carbonell, Janfreisy, Cruz Vicioso, Rossy, Katus, Linn, Quinn, Joseph, Hodges, Priscila, Meng, Yan, Strom, Samuel, Blauwendraat, Cornelis, Lohmann, Katja, Casaceli, Cynthia, Rao, Shilpa, Ghosh Galvelis, Kamalini, Naito, Anna, Beck, James, Alcalay, Roy

المصدر: Brain. 147(8)

مصطلحات موضوعية: GBA1, LRRK2, Parkinson’s disease, clinical trials, genetic counselling, genetic testing, Humans, Parkinson Disease, Genetic Testing, Male, Female, Glucosylceramidase, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, alpha-Synuclein, Aged, Middle Aged, Ubiquitin-Protein Ligases, Protein Kinases, Protein Deglycase DJ-1, Vesicular Transport Proteins, North America, Genetic Variation, Genetic Predisposition to Disease, Adult, Disclosure, Genetic Counseling, Canada, United States

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1tc6321g
https://escholarship.org/content/qt1tc6321g/qt1tc6321g.pdf

المؤلفون: Westenberger, Ana, Skrahina, Volha, Usnich, Tatiana, Beetz, Christian, Vollstedt, Eva-Juliane, Laabs, Björn-Hergen, Paul, Jefri, Curado, Filipa, Skobalj, Snezana, Gaber, Hanaa, Olmedillas, Maria, Bogdanovic, Xenia, Ameziane, Najim, Schell, Nathalie, Aasly, Jan, Afshari, Mitra, Agarwal, Pinky, Aldred, Jason, Alonso-Frech, Fernando, Anderson, Roderick, Araújo, Rui, Arkadir, David, Avenali, Micol, Balal, Mehmet, Benizri, Sandra, Bette, Sagari, Bhatia, Perminder, Bonello, Michael, Braga-Neto, Pedro, Brauneis, Sarah, Cardoso, Francisco, Cavallieri, Francesco, Classen, Joseph, Cohen, Lisa, Coletta, Della, Crosiers, David, Cullufi, Paskal, Dashtipour, Khashayar, Demirkiran, Meltem, de Carvalho Aguiar, Patricia, De Rosa, Anna, Djaldetti, Ruth, Dogu, Okan, Dos Santos Ghilardi, Maria, Eggers, Carsten, Elibol, Bulent, Ellenbogen, Aaron, Ertan, Sibel, Fabiani, Giorgio, Falkenburger, Björn, Farrow, Simon, Fay-Karmon, Tsviya, Ferencz, Gerald, Fonoff, Erich, Fragoso, Yara, Genç, Gençer, Gorospe, Arantza, Grandas, Francisco, Gruber, Doreen, Gudesblatt, Mark, Gurevich, Tanya, Hagenah, Johann, Hanagasi, Hasmet, Hassin-Baer, Sharon, Hauser, Robert, Hernández-Vara, Jorge, Herting, Birgit, Hinson, Vanessa, Hogg, Elliot, Hu, Michele, Hummelgen, Eduardo, Hussey, Kelly, Infante, Jon, Isaacson, Stuart, Jauma, Serge, Koleva-Alazeh, Natalia, Kuhlenbäumer, Gregor, Kühn, Andrea, Litvan, Irene, López-Manzanares, Lydia, Luxmore, McKenzie, Manandhar, Sujeena, Marcaud, Veronique, Markopoulou, Katerina, Marras, Connie, McKenzie, Mark, Matarazzo, Michele, Merello, Marcelo, Mollenhauer, Brit, Morgan, John, Mullin, Stephen, Musacchio, Thomas, Myers, Bennett, Negrotti, Anna, Nieves, Anette, Nitsan, Zeev, Oskooilar, Nader, Öztop-Çakmak, Özgür, Pal, Gian, Pavese, Nicola

المصدر: Brain. 147(8)

مصطلحات موضوعية: GBA1, LRRK2, Parkinson’s disease, genetic factors, genetic testing, next-generation sequencing, Humans, Parkinson Disease, Male, Female, Middle Aged, Aged, Genetic Testing, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Glucosylceramidase, alpha-Synuclein, Genetic Predisposition to Disease, Ubiquitin-Protein Ligases, Cohort Studies, Protein Kinases, Mutation, Adult

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4gx97158
https://escholarship.org/content/qt4gx97158/qt4gx97158.pdf

المؤلفون: Dederer, Verena, Sanz Murillo, Marta, Karasmanis, Eva, Hatch, Kathryn, Chatterjee, Deep, Preuss, Franziska, Abdul Azeez, Kamal, Nguyen, Landon, Galicia, Christian, Dreier, Birgit, Plückthun, Andreas, Versees, Wim, Mathea, Sebastian, Leschziner, Andres, Reck-Peterson, Samara, Knapp, Stefan

المصدر: Journal of Biological Chemistry. 300(7)

مصطلحات موضوعية: DARPin, LRRK2, Parkinson’s disease, Rab8a, WD40, cryo-electron microscopy, kinase, kinase inhibitor, microtubule, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Humans, Ankyrin Repeat, Parkinson Disease, HEK293 Cells, rab GTP-Binding Proteins, Phosphorylation, Cryoelectron Microscopy, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/65h9j1ct
https://escholarship.org/content/qt65h9j1ct/qt65h9j1ct.pdf

المؤلفون: Maekawa, Tatsunori^{Aff1, Aff2, Aff4, IDs10620024084947_cor1}, Motokawa, Ryuichi, Kawashima, Rei^{Aff1, Aff2, Aff4}, Tamaki, Shun^{Aff1, Aff2, Aff4}, Hara, Yusuke, Kawakami, Fumitaka^{Aff1, Aff3, Aff4}, Ichikawa, Takafumi^{Aff1, Aff2, Aff4}

المصدر: Digestive Diseases and Sciences. 69(8):2828-2840

المؤلفون: Sharma, Pallavi Kaila, Weng, Jui-Hung, Manschwetus, Jascha T, Wu, Jian, Ma, Wen, Herberg, Friedrich W, Taylor, Susan S

المصدر: Biochemical Journal. 481(4)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Parkinson's Disease, Neurodegenerative, Neurosciences, Brain Disorders, 2.1 Biological and endogenous factors, Aetiology, Neurological, Protein Serine-Threonine Kinases, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Leucine-Rich Repeat Proteins, Protein Domains, Mutation, Peptides, Phosphorylation, C-terminal helix, GaMD simulation, LRRK2, Parkinson's disease, peptide array, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5qb2056g

المؤلفون: Brown, Ethan, Goldman, Samuel, Coffey, Christopher, Siderowf, Andrew, Simuni, Tanya, Meng, Cheryl, Brumm, Michael, Caspell-Garcia, Chelsea, Marek, Kenneth, Tanner, Caroline

المصدر: Journal of Parkinsons Disease. 14(4)

مصطلحات موضوعية: GBA associated Parkinson’s disease, LRRK2 associated Parkinson’s disease, Parkinson’s disease, environmental exposure, pesticide exposure, Humans, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Female, Parkinson Disease, Male, Glucosylceramidase, Occupational Exposure, Pesticides, Aged, Middle Aged, Penetrance, Activities of Daily Living, Cognitive Dysfunction

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/94w7w3h0
https://escholarship.org/content/qt94w7w3h0/qt94w7w3h0.pdf

المؤلفون: Wetzel, Andrea^{Aff1, Aff6}, Lei, Si Hang, Liu, Tiansheng, Hughes, Michael P., Peng, Yunan, McKay, Tristan, Waddington, Simon N.^{Aff3, Aff4}, Grannò, Simone^{Aff1, Aff5}, Rahim, Ahad A., Harvey, Kirsten^{Aff1, IDs41598024631308_cor10}

المصدر: Scientific Reports. 14(1)

المؤلفون: Andrea Wetzel, Si Hang Lei, Tiansheng Liu, Michael P. Hughes, Yunan Peng, Tristan McKay, Simon N. Waddington, Simone Grannò, Ahad A. Rahim, Kirsten Harvey

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)

مصطلحات موضوعية: LRRK2, Wnt signaling, NFAT signaling, Parkinson’s diseases, Immune system, LRRK2 G2019S, Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/1938be2aee344346933815a42dfb5c2e

المؤلفون: Tripathi, Animan, Kumar, Pravir

المصدر: 2021 5th International Conference on Information Systems and Computer Networks (ISCON) Information Systems and Computer Networks (ISCON), 2021 5th International Conference on. :1-4 Oct, 2021

Relation: 2021 5th International Conference on Information Systems and Computer Networks (ISCON)

المؤلفون: Brinda, M.^Aff9, Medha Raj Reddy, R.^Aff9, Durwas, Sharavari Girish^Aff9, Ananthaswamy, Siddharth^Aff9, Shenoy, Rashmi S.^Aff9, Bhat, Savithri^Aff9

المساهمون: Tsihrintzis, George A., Series Editor^Aff1, Virvou, Maria, Series Editor^Aff2, Jain, Lakhmi C., Series Editor^Aff3, Dehuri, Satchidananda, editor^Aff4, Cho, Sung-Bae, editor^Aff5, Padhy, Venkat Prasad, editor^Aff6, Shanmugam, Poonkuntrun, editor^Aff7, Ghosh, Ashish, editor^Aff8

المصدر: Machine Intelligence, Tools, and Applications : Proceedings of the International Conference on Machine Intelligence, Tools, and Applications—ICMITA 2024. 40:220-230