المؤلفون: Johan Vande Voorde, Arafath K. Najumudeen, Rory T. Steven, Chelsea J. Nikula, Alex Dexter, Lucas B. Zeiger, Efstathios A. Elia, Ammar Nasif, Ariadna Gonzalez-Fernandez, Teresa Murta, Michael Gillespie, Catriona A. Ford, Tamsin R.M. Lannagan, Nikola Vlahov, Rachel A. Ridgway, Colin Nixon, Kathryn Gilroy, David M. Gay, Amy Burton, Bin Yan, Katherine Sellers, Vincen Wu, Yuchen Xiang, Engy Shokry, William Clark, Vivian S.W. Li, Simon T. Barry, Richard J.A. Goodwin, Zoltan Takats, Oliver D.K. Maddocks, David Sumpton, Mariia O. Yuneva, Andrew D. Campbell, Josephine Bunch, Owen J. Sansom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3d49a1f23b41d8dcc99c9cad29a72865
https://doi.org/10.1101/2023.03.12.531945

المؤلفون: Bin Yan, Chelsea J. Nikula, Owen J. Sansom, Spencer A. Thomas, Teresa Murta, Rory T. Steven, Alex Dexter, Andrew D. Campbell, Efstathios A Elia, Richard J. A. Goodwin, Zoltan Takats, Josephine Bunch, Lucas B. Zeiger

المصدر: Analytical Chemistry. 93:2309-2316

مصطلحات موضوعية: Data processing, Chemistry, business.industry, Dimensionality reduction, 010401 analytical chemistry, Pattern recognition, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences, Analytical Chemistry, Visualization, Unsupervised learning, Segmentation, Artificial intelligence, Cluster analysis, business, Spatial analysis, Selection (genetic algorithm)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c143ef9f3301c0c340a9126a7814be
https://doi.org/10.1021/acs.analchem.0c04179

المؤلفون: Jim Cassidy, Owen J. Sansom, William C. Clark, Luis Serrano, Volker M. Stucke, Martin J Drysdale, Martin R Turner, Arafath Kaja Najumudeen, R.P. Fordham, Karen Pickering, Lucas B. Zeiger, Ewan J. McGhee, Saskia M. Brachmann, Ann Hedley, Andrew D. Campbell, Kathryn Gilroy, Jeanette A. Johansson, Maureen M. Bain, David F. Vincent, Kevin Myant, Christina Kiel, Kurt I. Anderson, Benjamin LeRoy Miller, Angeliki Malliri, S.R. van Hoof, Sigrid K. Fey, Jan Paul Medema, E.B. Unal, Anna-Karin E. Johnsson, Catherine Nixon, Laura M. Machesky, Douglas Strathdee

المساهمون: Center of Experimental and Molecular Medicine, Radiotherapy, CCA - Cancer biology and immunology, Najumudeen, AK [0000-0002-3764-5721], Zeiger, LB [0000-0002-8712-3112], Gay, DM [0000-0002-7407-1245], Machesky, LM [0000-0002-7592-9856], Nixon, C [0000-0002-8085-2160], Johnsson, AE [0000-0002-0018-700X], Strathdee, D [0000-0003-2959-4327], Anderson, KI [0000-0002-9324-9598], Malliri, A [0000-0001-6848-090X], Turner, M [0000-0002-3801-9896], Serrano, L [0000-0002-5276-1392], Myant, K [0000-0001-8017-1093], Campbell, AD [0000-0003-3930-1276], Sansom, OJ [0000-0001-9540-3010], Apollo - University of Cambridge Repository, Najumudeen, A. K. [0000-0002-3764-5721], Zeiger, L. B. [0000-0002-8712-3112], Gay, D. M. [0000-0002-7407-1245], Machesky, L. M. [0000-0002-7592-9856], Nixon, C. [0000-0002-8085-2160], Johnsson, A. E. [0000-0002-0018-700X], Strathdee, D. [0000-0003-2959-4327], Anderson, K. I. [0000-0002-9324-9598], Malliri, A. [0000-0001-6848-090X], Turner, M. [0000-0002-3801-9896], Serrano, L. [0000-0002-5276-1392], Myant, K. [0000-0001-8017-1093], Campbell, A. D. [0000-0003-3930-1276], Sansom, O. J. [0000-0001-9540-3010]

المصدر: Nature communications, 12(1):56. Nature Publishing Group
Nature Communications
Pickering, KA, Gilroy, K, Cassidy, JW, Fey, SK, Najumudeen, AK, Zeiger, LB, Vincent, DF, Gay, DM, Johansson, J, Fordham, RP, Miller, B, Clark, W, Hedley, A, Unal, EB, Kiel, C, McGhee, E, Macheskey, LM, Nixon, C, Johnsson, AE, Bain, M, Strathdee, D, van Hoof, SR, Medema, JP, Anderson, KI, Brachmann, SM, Stucke, VM, Malliri, A, Drysdale, M, Turner, M, Serrano, L, Myant, K B, Campbell, AD & Sansom, OJ 2021, ' A RAC-GEF network critical for early intestinal tumourigenesis ', Nature Communications . https://doi.org/10.1038/s41467-020-20255-4
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
University of Edinburgh-PURE

مصطلحات موضوعية: 0301 basic medicine, VAV3, rac1 GTP-Binding Protein, VAV2, Carcinogenesis, Homeòstasi, General Physics and Astronomy, Imaging, 0302 clinical medicine, Guanine Nucleotide Exchange Factors, Homeostasis, T-Lymphoma Invasion and Metastasis-inducing Protein 1, Wnt Signaling Pathway, Mice, Knockout, Multidisciplinary, Wnt signaling pathway, article, Phenotype, Up-Regulation, Colon cancer, Intestines, Organ Specificity, 030220 oncology & carcinogenesis, 64/60, Signal transduction, 631/67/70, Signal Transduction, Science, Adenomatous Polyposis Coli Protein, RAC1, 13/106, 631/67/1504/1885/1393, Biology, General Biochemistry, Genetics and Molecular Biology, 38/91, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Downregulation and upregulation, 14/33, Animals, Proto-Oncogene Proteins c-vav, Cancer models, Tumors, General Chemistry, 030104 developmental biology, Mutation, 13/51, Cancer research, Intestins -- Càncer, Genètica

وصف الملف: application/pdf; text/xml; application/zip

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a4588ea791829c408931197ab3e425
https://pure.amc.nl/en/publications/a-racgef-network-critical-for-early-intestinal-tumourigenesis(1d3b7cc2-5483-46a6-accd-e659022a288b).html

المؤلفون: Chiara Volani, Claudia Lamina, Juliane Kager, Marina Barros-Pinkelnig, Markus Seifert, J. Hirsch, Verena Petzer, Gerald J. Obermair, Heike Meiselbach, Piotr Tymoszuk, Stefan Coassin, Malte Asshoff, David Haschka, Lucas B Zeiger, Konstantin Strauch, Stefanie Dichtl, Sieghart Sopper, Laura von Raffay, Manfred Nairz, Florian Kronenberg, Patrizia Moser, Georg F. Vogel, Natascha Brigo, Egon Demetz, Nicole Probst-Hensch, Lara Valente de Souza, Christiane Heim, Richard Hilbe, Pedro Marques-Vidal, Daniela Lener, Stefan Kiechl, Julia Halper, Guenter Weiss, S Macheiner, Christine Fischer, Johann Willeit, Annette Peters, M. Graber, Can Gollmann-Tepeköylü, Medea Imboden, Bernhard Paulweber, Johanna M. Gostner, Johannes Holfeld, Ivan Tancevski, Raimund Pechlaner, Kristina Auer, Christa Pfeifhofer-Obermair, Andrea Schroll, Anna Boehm, Igor Theurl, Cornelia Ablinger

المصدر: Eur. Heart J. 41, 3949–3959 (2020)

مصطلحات موضوعية: Apolipoprotein E, medicine.medical_specialty, Kupffer Cells, Single-nucleotide polymorphism, 030204 cardiovascular system & hematology, Abca1, Atherosclerosis, Haemochromatosis, Ldl Receptor, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Internal medicine, medicine, ABCA1 Gene, Animals, Homeostasis, Humans, Clustered Regularly Interspaced Short Palindromic Repeats, Hemochromatosis Protein, Hemochromatosis, 030304 developmental biology, 0303 health sciences, biology, Cholesterol, business.industry, Cholesterol, LDL, medicine.disease, Endocrinology, chemistry, Receptors, LDL, ABCA1, LDL receptor, biology.protein, lipids (amino acids, peptides, and proteins), Cardiology and Cardiovascular Medicine, business, Genome-Wide Association Study

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb1e394d9595c770cab6ebbb7a6e1172
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=58748

المؤلفون: Owen J. Sansom, Patrizia Cammareri, Edward Morrissey, Douglas J. Winton, Lotte Bruens, M. Solar-Abboud, William J. Faller, M. E. McLaughlin, Andrew D. Campbell, Lucas B. Zeiger, Colin Nixon, Rachel A. Ridgway, Michael C. Hodder, David J. Huels, Hugo J. Snippert, J. van Rheenen

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications
Nature Communications, 9(1). Nature Publishing Group

مصطلحات موضوعية: 0301 basic medicine, Chemistry(all), Carcinogenesis, Pyridines, General Physics and Astronomy, Ligands, medicine.disease_cause, Biochemistry, Mice, 0302 clinical medicine, Intestinal mucosa, Enzyme Inhibitors, Intestinal Mucosa, lcsh:Science, Wnt Signaling Pathway, Multidisciplinary, Stem Cells, Wnt signaling pathway, LGR5, Cell biology, Cell Transformation, Neoplastic, Pyrazines, 030220 oncology & carcinogenesis, Monoclonal, Stem cell, Colorectal Neoplasms, Adenoma, Science, Adenomatous Polyposis Coli Protein, Mice, Transgenic, Biology, Physics and Astronomy(all), Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, medicine, Animals, Secretion, Biochemistry, Genetics and Molecular Biology(all), Membrane Proteins, General Chemistry, Mice, Inbred C57BL, 030104 developmental biology, lcsh:Q, Acyltransferases, Homeostasis, Genetics and Molecular Biology(all)

وصف الملف: image/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c361aafe006f0adf7c07521f0b815b
https://doaj.org/article/1a2839335a8e4193bb5d85dedd7c98ab