المؤلفون: Dominic D. G. Owens, Giorgio Anselmi, A. Marieke Oudelaar, Damien J. Downes, Alessandro Cavallo, Joe R. Harman, Ron Schwessinger, Akin Bucakci, Lucas Greder, Sara de Ornellas, Danuta Jeziorska, Jelena Telenius, Jim R. Hughes, Marella F. T. R. de Bruijn

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/2c70bda05c964692b2499b46b84229b8

المؤلفون: Lei Ye, Sophia Zhang, Lucas Greder, James Dutton, Susan A Keirstead, Mike Lepley, Liying Zhang, Dan Kaufman, Jianyi Zhang

المصدر: PLoS ONE, Vol 8, Iss 1, p e53764 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3542360?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/f00aee50a8854ffb9dab9d8549376b51

المؤلفون: Danuta M. Jeziorska, Hughes, de Bruijn Mf, Jelena Telenius, Harman, Damien J. Downes, Andrea Cavallo, Lucas Greder, Bucakci A, Ron Schwessinger, De Ornellas S, Dominic D G Owens, Giorgio Anselmi, A M Oudelaar

المصدر: Nature Communications
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)

مصطلحات موضوعية: Science, Gene Expression, General Physics and Astronomy, Cell Cycle Proteins, Biology, General Biochemistry, Genetics and Molecular Biology, Mesoderm, Mice, chemistry.chemical_compound, hemic and lymphatic diseases, Gene expression, Animals, Promoter Regions, Genetic, Enhancer, Transcription factor, Regulation of gene expression, Multidisciplinary, Gene Expression Regulation, Developmental, Cell Differentiation, Promoter, DNA, General Chemistry, Hematopoietic Stem Cells, Chromatin, Cell biology, RUNX1, chemistry, CTCF, Core Binding Factor Alpha 2 Subunit, embryonic structures, Nucleic Acid Conformation

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab771d77e970017782fd87ea8de1292
https://hdl.handle.net/21.11116/0000-000A-2BF1-621.11116/0000-000A-2BF4-3

المؤلفون: Claire S. Simon, Lucas Greder, Elizabeth J. Robertson, Anna D. Senft, Ivan Imaz-Rosshandler, Catherine Porcher, Luke T. G. Harland, Marella F. T. R. de Bruijn, John C. Marioni, Berthold Göttgens, Elizabeth K. Bikoff, Ita Costello

المساهمون: Simon, Claire S [0000-0001-9614-1403], Senft, Anna D [0000-0001-9351-9132], Costello, Ita [0000-0002-6770-3769], Göttgens, Berthold [0000-0001-6302-5705], Marioni, John C [0000-0001-9092-0852], Porcher, Catherine [0000-0002-9015-5203], de Bruijn, Marella FTR [0000-0002-4934-4125], Robertson, Elizabeth J [0000-0001-6562-0225], Apollo - University of Cambridge Repository

المصدر: Nature cell biology

مصطلحات موضوعية: Male, Mesoderm, Hemangioblasts, Eomesodermin, Biology, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pregnancy, medicine, Animals, RNA-Seq, Yolk sac, Transcription factor, Embryonic Stem Cells, T-Cell Acute Lymphocytic Leukemia Protein 1, 030304 developmental biology, Yolk Sac, Mice, Knockout, 0303 health sciences, Cell Biology, Embryonic stem cell, Vascular Endothelial Growth Factor Receptor-2, Cell biology, Haematopoiesis, medicine.anatomical_structure, T-box, RUNX1, chemistry, 030220 oncology & carcinogenesis, embryonic structures, Core Binding Factor Alpha 2 Subunit, Female, Single-Cell Analysis, T-Box Domain Proteins

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebea60a8636375dc06989f547165bfe6

المؤلفون: Joe Harman, Peter J. McHugh, Lucas Greder, Dominic D G Owens, Vincent Frontera, Philip Hublitz, Marella F. T. R. de Bruijn, Lydia Teboul, Alasdair J Allan, Akin Bucakci, Adam Caulder, Gemma F. Codner

المصدر: Nucleic Acids Research

مصطلحات موضوعية: DNA End-Joining Repair, Chromosome Breakpoints, Genome Integrity, Repair and Replication, Biology, Cell Line, Mice, 03 medical and health sciences, 0302 clinical medicine, Genome editing, Genetics, Animals, Deoxyribonuclease I, CRISPR, Allele, Genotyping, Sequence Deletion, 030304 developmental biology, Gene Editing, 0303 health sciences, Nuclease, Models, Genetic, Cas9, RNA, Endonucleases, Chromosomes, Mammalian, biology.protein, CRISPR-Cas Systems, Chromosome Deletion, 030217 neurology & neurosurgery, RNA, Guide, Kinetoplastida

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03dd16dfb3c903caac34c998df1bb403
https://doi.org/10.1093/nar/gkz459

المؤلفون: Ita Costello, Claire S. Simon, Ivan Imaz-Rosshandler, Luke T. G. Harland, Elizabeth J. Robertson, Marella F. T. R. de Bruijn, Anna D. Senft, Catherine Porcher, John C. Marioni, Berthold Göttgens, Lucas Greder, Elizabeth K. Bikoff

المصدر: Nature Cell Biology. 23:293-293

مصطلحات موضوعية: T-box, medicine.anatomical_structure, medicine, Eomesodermin, Cell Biology, Progenitor cell, Biology, Yolk sac, Transcription factor, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::82c374cd6901191233dea5d4f3f838f3
https://doi.org/10.1038/s41556-021-00645-6

المؤلفون: Lucas Greder, Anna D. Senft, Elizabeth K. Bikoff, Elizabeth J. Robertson, Catherine Porcher, Ita Costello, Ivan Imaz-Rosshandler, John C. Marioni, Claire S. Simon, Luke T. G. Harland, Marella F. T. R. de Bruijn, Berthold Göttgens

المصدر: Experimental Hematology. 88:S34

مصطلحات موضوعية: Hemogenic endothelium, Cancer Research, Mesoderm, Eomesodermin, Context (language use), Cell Biology, Hematology, Biology, Embryonic stem cell, Cell biology, chemistry.chemical_compound, medicine.anatomical_structure, RUNX1, chemistry, embryonic structures, Genetics, medicine, NODAL, Induced pluripotent stem cell, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8627741a935121b7d0d17d3b924ec764
https://doi.org/10.1016/j.exphem.2020.09.180

المؤلفون: Lucas Greder, Jonathan M.W. Slack, James R. Dutton, Anannya Banga

المصدر: Gene therapy

مصطلحات موضوعية: Blood Glucose, Agonist, insulin, medicine.medical_specialty, Maf Transcription Factors, Large, medicine.drug_class, Ductal cells, Liver cytology, medicine.medical_treatment, Genetic Vectors, Nerve Tissue Proteins, Biology, Article, PPAR agonist, Diabetes Mellitus, Experimental, Mice, Insulin-Secreting Cells, Internal medicine, Diabetes mellitus, Basic Helix-Loop-Helix Transcription Factors, Genetics, medicine, Animals, WY14643, Molecular Biology, Homeodomain Proteins, Pdx1, diabetes, Anticholesteremic Agents, Insulin, Genetic Therapy, Dependovirus, Streptozotocin, medicine.disease, Combined Modality Therapy, MafA, 3. Good health, Pyrimidines, Endocrinology, Liver, Neurogenin3, Trans-Activators, Molecular Medicine, PDX1, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2f9b768f8ec6792f038131f5b2d6f2
https://doi.org/10.1038/gt.2013.50

المؤلفون: Lucas Greder, James R. Dutton, Shunan Li, Yoav Segal, Jonathan M.W. Slack, Abdulrahim A. Sajini, Sandeep Gupta, Md. Joynal Abedin

المصدر: STEM CELLS. 30:2596-2601

مصطلحات موضوعية: Regulation of gene expression, Genetics, Cell division, Somatic cell, Transgene, Cre recombinase, Endogeny, Cell Biology, Biology, Cell biology, embryonic structures, Molecular Medicine, Induced pluripotent stem cell, Reprogramming, reproductive and urinary physiology, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a02b770de8d15638b6279a6aacac8187
https://doi.org/10.1002/stem.1216

المؤلفون: Ersin Akinci, Lucas Greder, Jonathan M.W. Slack, James R. Dutton, Anannya Banga

المصدر: Proceedings of the National Academy of Sciences. 109:15336-15341

مصطلحات موضوعية: Blood Glucose, Male, medicine.medical_specialty, Cellular differentiation, medicine.medical_treatment, Mice, SCID, Biology, Diabetes Mellitus, Experimental, Mice, Mice, Inbred NOD, Insulin-Secreting Cells, Internal medicine, medicine, Animals, Insulin, Pancreas, Dense core granule, Multidisciplinary, Models, Genetic, Cell Differentiation, SOX9 Transcription Factor, Biological Sciences, Cell sorting, Streptozotocin, Cell biology, Microscopy, Electron, medicine.anatomical_structure, Endocrinology, Liver, PDX1, Female, Reprogramming, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98576308625c653695614951c5b08c84
https://doi.org/10.1073/pnas.1201701109