يعرض 1 - 10 نتائج من 10 نتيجة بحث عن '"Lucy Penfold"', وقت الاستعلام: 0.84s تنقيح النتائج
  1. 1
    دورية أكاديمية
    AMPK activation protects against prostate cancer by inducing a catabolic cellular state

    المؤلفون: Lucy Penfold, Angela Woods, Alice E. Pollard, Julia Arizanova, Eneko Pascual-Navarro, Phillip J. Muckett, Marian H. Dore, Alex Montoya, Chad Whilding, Louise Fets, Joao Mokochinski, Theodora A. Constantin, Anabel Varela-Carver, Damien A. Leach, Charlotte L. Bevan, Alexander Yu. Nikitin, Zoe Hall, David Carling

    المصدر: Cell Reports, Vol 42, Iss 4, Pp 112396- (2023)

    مصطلحات موضوعية: CP: Cancer, CP: Metabolism, Biology (General), QH301-705.5

    وصف الملف: electronic resource

    Relation: http://www.sciencedirect.com/science/article/pii/S2211124723004072; https://doaj.org/toc/2211-1247

    URL الوصول: https://doaj.org/article/11a6b824917b48fc8d5c5b5a9e0faa99

    View record from ScienceDirect Full Text Finder
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  2. 2
    Supplementary Fig. S5 from CAMKK2 Promotes Prostate Cancer Independently of AMPK via Increased Lipogenesis

    المؤلفون: David Carling, Alice Pollard, Rebecca Graham, Shuai Zhang, Tera R. Kent, Alexander Yu. Nikitin, Phillip Muckett, Angela Woods, Lucy Penfold

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121134ba40f03ca89d7f725296e07013
    https://doi.org/10.1158/0008-5472.22420541

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  3. 3
    Supplementary Table 1 from CAMKK2 Promotes Prostate Cancer Independently of AMPK via Increased Lipogenesis

    المؤلفون: David Carling, Alice Pollard, Rebecca Graham, Shuai Zhang, Tera R. Kent, Alexander Yu. Nikitin, Phillip Muckett, Angela Woods, Lucy Penfold

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8751cefff8b4e3935887bf39ca5f78
    https://doi.org/10.1158/0008-5472.22420535

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  4. 4
    Data from CAMKK2 Promotes Prostate Cancer Independently of AMPK via Increased Lipogenesis

    المؤلفون: David Carling, Alice Pollard, Rebecca Graham, Shuai Zhang, Tera R. Kent, Alexander Yu. Nikitin, Phillip Muckett, Angela Woods, Lucy Penfold

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f236d9cc8cfdf0c50d59e2474548af31
    https://doi.org/10.1158/0008-5472.c.6510680.v1

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  5. 5
    The CDK7 inhibitor CT7001 (Samuraciclib) targets proliferation pathways to inhibit advanced prostate cancer

    المؤلفون: Theodora A. Constantin, Anabel Varela-Carver, Kyle K. Greenland, Gilberto Serrano de Almeida, Ellen Olden, Lucy Penfold, Simon Ang, Alice Ormrod, Damien A. Leach, Chun-Fui Lai, Edward K. Ainscow, Ash K. Bahl, David Carling, Matthew J. Fuchter, Simak Ali, Charlotte L. Bevan

    مصطلحات موضوعية: Cancer Research, Oncology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eca8b4b5eb80fb0db7513376e511998
    http://hdl.handle.net/10044/1/103960

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  6. 6
    Chronic activation of AMP-activated protein kinase leads to early-onset polycystic kidney phenotype

    المؤلفون: Chad Whilding, Mohammad Bohlooly-Y, Laura A. B. Wilson, Alice E. Pollard, Lucy Penfold, David Carling, Patricia Wilson, Phillip J. Muckett

    المصدر: Clinical Science. 135:2393-2408

    مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Autosomal dominant polycystic kidney disease, Renal function, Mice, Transgenic, AMP-Activated Protein Kinases, Kidney, AMP-activated protein kinase, Hexokinase, Internal medicine, Cyclic AMP, medicine, Animals, Humans, Genetic Predisposition to Disease, Extracellular Signal-Regulated MAP Kinases, Protein kinase A, Cystic kidney, Polycystic Kidney Diseases, biology, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, urogenital system, Autophagy, Age Factors, AMPK, General Medicine, Polycystic Kidney, Autosomal Dominant, medicine.disease, Enzyme Activation, Phenotype, Endocrinology, medicine.anatomical_structure, biology.protein, Female, Energy Metabolism, Signal Transduction

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bae06094ff4e2bea1931b0af71b35ef
    https://doi.org/10.1042/cs20210821

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  7. 7
    Systems level profiling of chemotherapy-induced stress resolution in cancer cells reveals druggable trade-offs

    المؤلفون: Aristeidis Chaidos, Paolo Piazza, Daria Capece, Kevin Blighe, Alexandros P. Siskos, Lucy Penfold, Denise Thiel, Elena López-Jiménez, Martin Kaiser, Valentina S. Caputo, Katarzyna Parzych, Diego A. Oyarzún, Zijing Liu, Hector C. Keun, Guido Franzoso, Ambrosius P. Snijders, Hibah A Al-Sadah, Mauricio Barahona, Anastasios Karadimitris, Vesela Encheva, Paula Saavedra-García, Xiaobei Xiong, Holger W. Auner, Monica Roman-Trufero, Yirun Miao, Marilena Christoforou

    المساهمون: Amgen (Europe) GmbH, Cancer Research UK, Imperial Health Charity, Engineering & Physical Science Research Council (EPSRC), Bloodwise, Imperial College Healthcare NHS Trust- BRC Funding, Medical Research Council (MRC), Syngenta Ltd

    المصدر: Saavedra-García, P, Roman-Trufero, M, Al-Sadah, H A, Blighe, K, López-Jiménez, E, Christoforou, M, Penfold, L, Capece, D, Xiong, X, Miao, Y, Parzych, K, Caputo, V S, Siskos, A P, Encheva, V, Liu, Z, Thiel, D, Kaiser, M F, Piazza, P, Chaidos, A, Karadimitris, A, Franzoso, G, Snijders, A P, Keun, H C, Oyarzún, D A, Barahona, M & Auner, H W 2021, ' Systems level profiling of chemotherapy-induced stress resolution in cancer cells reveals druggable trade-offs ', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 17, e2018229118 . https://doi.org/10.1073/pnas.2018229118
    Proceedings of the National Academy of Sciences of the United States of America

    مصطلحات موضوعية: Medical Sciences, Systems Analysis, Proteome, Physiological, Druggability, Antineoplastic Agents, Computational biology, Biology, Stress, Cell Line, Transcriptome, Stress, Physiological, Cell Line, Tumor, Neoplasms, Metabolome, Autophagy, GCN2, Metabolism, Myeloma, Proteasome, Proteostasis, Humans, Mitochondria, Multiple Myeloma, Proteasome Inhibitors, Proteolysis, Multidisciplinary, Tumor, proteostasis, Lipid metabolism, Biological Sciences, myeloma, proteasome, Cancer cell, metabolism

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ac6903923803fa6b211619ecadade3
    http://hdl.handle.net/10044/1/87287

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  8. 8
    AMPK activation protects against diet induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue

    المؤلفون: Sanjay Khadayate, Michael R. Duchen, David M. Smith, Rebeca Fiadeiro, Therese Admyre, Mikael Bjursell, Aurélie Bornot, Luís Martins, Angela Woods, Chad Whilding, Alice E. Pollard, Lucy Penfold, Laura A. B. Wilson, Vassilios N. Kotiadis, Mohammad Bohlooly-Y, Phillip J. Muckett, Jon Read, Michael A. Snowden, Alessandro Sardini, Maryam Clausen, David Carling, Daniel Sutton

    المصدر: Nature metabolism

    مصطلحات موضوعية: Adenosine monophosphate, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Adipose Tissue, White, Population, Subcutaneous Fat, Adipose tissue, Mice, Transgenic, White adipose tissue, Article, 03 medical and health sciences, chemistry.chemical_compound, Endocrinology & Metabolism, Mice, 0302 clinical medicine, Physiology (medical), Internal medicine, Internal Medicine, medicine, STEATOSIS, CREATINE, Animals, Obesity, BROWN, Protein kinase A, education, Uncoupling Protein 1, 030304 developmental biology, 0303 health sciences, education.field_of_study, Science & Technology, Adenylate Kinase, AMPK, Thermogenesis, Cell Biology, BEIGE, ADIPOCYTES, Diet, Enzyme Activation, Endocrinology, chemistry, Female, HEALTH, Adenosine triphosphate, Life Sciences & Biomedicine, 030217 neurology & neurosurgery

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee1b02ac41391ec4802c5558731300e
    http://hdl.handle.net/10044/1/69486

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  9. 9
    Integrated Systems Level Examination of Proteasome Inhibitor Stress Recovery in Myeloma Cells Reveals Druggable Vulnerabilities Linked to Multiple Metabolic Processes

    المؤلفون: Katarzyna Parzych, Holger W. Auner, Martin Kaiser, Lucy Penfold, Hector C. Keun, Kevin Blighe, Hibah A Al-Sadah, Xiaobei Xiong, Zijing Liu, Elena López-Jiménez, Vesela Encheva, Diego A. Oyarzún, Paolo Piazza, Denise Thiel, Ambrosius P. Snijders, Mauricio Barahona, Valentina S. Caputo, Paula Saavedra-García

    المصدر: Blood. 134:1818-1818

    مصطلحات موضوعية: Stress recovery, biology, Immunology, Druggability, Cell Biology, Hematology, medicine.disease, Biochemistry, Carfilzomib, Cell biology, Gene expression profiling, chemistry.chemical_compound, Ubiquitin, chemistry, Proteome, biology.protein, medicine, Proteasome inhibitor, Multiple myeloma, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f9942dba162f448792c082e55a29926e
    https://doi.org/10.1182/blood-2019-121549

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  10. 10
    CAMKK2 Promotes Prostate Cancer Independently of AMPK via Increased Lipogenesis

    المؤلفون: Alice E. Pollard, David Carling, Rebecca Graham, Angela Woods, Lucy Penfold, Alexander Yu. Nikitin, Phillip J. Muckett, Shuai Zhang, Tera R. Kent

    المصدر: Cancer research. 78(24)

    مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, PROGRESSION, AMP-Activated Protein Kinases, Prostate cancer, Mice, Cell Movement, Medicine, Phosphorylation, CAMKK2, Mice, Knockout, biology, ACTIVATED PROTEIN-KINASE, Cell Cycle, ANDROGEN RECEPTOR, INHIBITOR, Naphthalimides, Oncology, Receptors, Androgen, Lipogenesis, Female, REGULATOR, Life Sciences & Biomedicine, Signal Transduction, Cell Survival, BETA, Calcium-Calmodulin-Dependent Protein Kinase Kinase, METABOLISM, Adenocarcinoma, Article, MECHANISMS, 03 medical and health sciences, Cell Line, Tumor, PTEN, Animals, Humans, 1112 Oncology and Carcinogenesis, Neoplasm Invasiveness, Oncology & Carcinogenesis, Protein kinase A, Cell Proliferation, Science & Technology, business.industry, AMPK, Cancer, Prostatic Neoplasms, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Cancer cell, Cancer research, biology.protein, CELL-GROWTH, Benzimidazoles, CRISPR-Cas Systems, business, RESISTANCE, Gene Deletion

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd236881a86b6d130bc7cc124dcee63
    https://pubmed.ncbi.nlm.nih.gov/30242113

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