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المؤلفون: Bruce R. Ksander, Morgan E. Levine, Emma Hoffmann, Luis A. Rajman, Zhigang He, Meredith S Gregory-Ksander, Michael Bonkowski, Anitha Krishnan, Jae-Hyun Yang, Chen Wang, Alice E. Kane, Ekaterina Korobkina, Songlin Zhou, Xiao Tian, Margarita Meer, George M. Church, Yu D, Michael B. Schultz, Karolina Chwalek, Noah Davidsohn, Steve Horvath, Yuancheng Lu, Qiurui Zeng, Konrad Hochedlinger, David A. Sinclair, Daniel L. Vera, Vadim N. Gladyshev, Margarete M. Karg, Benedikt Brommer
المصدر: Nature
مصطلحات موضوعية: Retinal Ganglion Cells, 0301 basic medicine, Aging, Cell Survival, Genetic Vectors, Kruppel-Like Transcription Factors, Biology, Eye, Retinal ganglion, Article, Dioxygenases, Epigenesis, Genetic, Kruppel-Like Factor 4, Mice, 03 medical and health sciences, 0302 clinical medicine, SOX2, Cell Line, Tumor, Proto-Oncogene Proteins, medicine, Animals, Humans, Epigenetics, Axon, Vision, Ocular, Multidisciplinary, SOXB1 Transcription Factors, Regeneration (biology), Glaucoma, DNA Methylation, Dependovirus, Cellular Reprogramming, Axons, Nerve Regeneration, Cell biology, DNA-Binding Proteins, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Optic Nerve Injuries, DNA methylation, Female, Ectopic expression, Transcriptome, Octamer Transcription Factor-3, Reprogramming, 030217 neurology & neurosurgery
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المؤلفون: Jae-Hyun Yang, Motoshi Hayano, Patrick T. Griffin, João A. Amorim, Michael S. Bonkowski, John K. Apostolides, Elias L. Salfati, Marco Blanchette, Elizabeth M. Munding, Mital Bhakta, Yap Ching Chew, Wei Guo, Xiaojing Yang, Sun Maybury-Lewis, Xiao Tian, Jaime M. Ross, Giuseppe Coppotelli, Margarita V. Meer, Ryan Rogers-Hammond, Daniel L. Vera, Yuancheng Ryan Lu, Jeffrey W. Pippin, Michael L. Creswell, Zhixun Dou, Caiyue Xu, Sarah J. Mitchell, Abhirup Das, Brendan L. O’Connell, Sachin Thakur, Alice E. Kane, Qiao Su, Yasuaki Mohri, Emi K. Nishimura, Laura Schaevitz, Neha Garg, Ana-Maria Balta, Meghan A. Rego, Meredith Gregory-Ksander, Tatjana C. Jakobs, Lei Zhong, Hiroko Wakimoto, Jihad El Andari, Dirk Grimm, Raul Mostoslavsky, Amy J. Wagers, Kazuo Tsubota, Stephen J. Bonasera, Carlos M. Palmeira, Jonathan G. Seidman, Christine E. Seidman, Norman S. Wolf, Jill A. Kreiling, John M. Sedivy, George F. Murphy, Richard E. Green, Benjamin A. Garcia, Shelley L. Berger, Philipp Oberdoerffer, Stuart J. Shankland, Vadim N. Gladyshev, Bruce R. Ksander, Andreas R. Pfenning, Luis A. Rajman, David A. Sinclair
المصدر: Cell. 186:305-326.e27
مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a40d556fd25f6db5d4a9f1a0234305aa
https://doi.org/10.1016/j.cell.2022.12.027 -
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المؤلفون: Brendan O'Connell, Xiaojing Yang, Jaime M. Ross, Yuancheng Lu, Jonathan G. Seidman, Mital Bhakta, Amy J. Wagers, João A. Amorim, Qiao Su, Bruce R. Ksander, Jae-Hyun Yang, Jill A. Kreiling, Elias L. Salfati, Stuart J. Shankland, Richard E. Green, Christine E. Seidman, Ana-Maria Balta, Andreas R. Pfenning, George F. Murphy, Michael Bonkowski, Benjamin A. Garcia, Luis A. Rajman, Patrick Griffin, Marco Blanchette, Yasuaki Mohri, Meghan A. Rego, Sarah J. Mitchell, Meredith S Gregory-Ksander, Kazuo Tsubota, Sachin Thakur, Raul Mostoslavsky, Caiyue Xu, Hiroko Wakimoto, John M. Sedivy, Norman S. Wolf, Philipp Oberdoerffer, Yap Ching Chew, John K. Apostolides, Alice E. Kane, Michael L. Creswell, Laura Schaevitz, Motoshi Hayano, Zhixun Dou, Margarita V. Meer, Giuseppe Coppotelli, Elizabeth M. Munding, Xiao Tian, Carlos M. Palmeira, Wei Guo, Shelley L. Berger, Tatjana C. Jakobs, Daniel L. Vera, Emi K. Nishimura, Lei Zhong, David A. Sinclair, Abhirup Das, Jeffrey W. Pippin, Vadim N. Gladyshev, Stephen J. Bonasera, Neha Garg
المصدر: SSRN Electronic Journal.
مصطلحات موضوعية: Senescence, History, Polymers and Plastics, DNA damage, Epigenome, Biology, Industrial and Manufacturing Engineering, Chromatin, Cell biology, KLF4, Ectopic expression, sense organs, Epigenetics, Business and International Management, Reprogramming
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::245f07f1a3ddd3b145824aa1a6d8802f
https://doi.org/10.2139/ssrn.3951490 -
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المؤلفون: Lei Zhong, Amy J. Wagers, Elias L. Salfati, Michael Bonkowski, Sarah J. Mitchell, Daniel L. Vera, Giuseppe Coppotelli, Patrick Griffin, Meredith S Gregory-Ksander, Xiaojing Yang, Wei Guo, Jonathan G. Seidman, Alice E. Kane, Yap Ching Chew, Jaime M. Ross, Tatjana C. Jakobs, Yasuaki Mohri, Carlos M. Palmeira, Laura Schaevitz, Emi K. Nishimura, Jae-Hyun Yang, David A. Sinclair, George F. Murphy, Abhirup Das, Luis A. Rajman, Sachin Thakur, Motoshi Hayano, Raul Mostoslavsky, Stephen J. Bonasera, Neha Garg, Christine E. Seidman, Hiroko Wakimoto, Philipp Oberdoerffer, Kazuo Tsubota, John M. Sedivy, Ana-Maria Balta, Jill A. Kreiling, Meghan A. Rego, Norman S. Wolf, João A. Amorim, Bruce R. Ksander
مصطلحات موضوعية: Genome instability, 0303 health sciences, biology, DNA damage, fungi, Epigenome, Cell biology, Chromatin, chemistry.chemical_compound, 03 medical and health sciences, Histone, 0302 clinical medicine, chemistry, DNA methylation, biology.protein, sense organs, Epigenetics, DNA, 030217 neurology & neurosurgery, 030304 developmental biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048c78ce26b9b695f04d178d7e0716fb
https://doi.org/10.1101/808659 -
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المؤلفون: Alvin J. Y. Ling, Clemens Steegborn, Vera Gorbunova, Jun Li, Dapeng Zhang, Bo Qin, Michael Bonkowski, David A. Sinclair, Basil P. Hubbard, Sébastien Moniot, Zhenkun Lou, L. Aravind, Luis A. Rajman
المصدر: Science. 355:1312-1317
مصطلحات موضوعية: 0301 basic medicine, Multidisciplinary, DNA repair, DNA damage, Nicotinamide adenine dinucleotide, Biology, NAD binding, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, PARP1, Biochemistry, chemistry, DNA Repair Protein, biology.protein, NAD+ kinase, Polymerase
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::aa0ff8bba773533c07c5bd4b73d1ca00
https://doi.org/10.1126/science.aad8242 -
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المؤلفون: David A. Sinclair, Benedikt Brommer, Michael Bonkowski, Anitha Krishnan, Konrad Hochedlinger, Margarita Meer, Yu D, Bruce R. Ksander, James Chih-Hsin Yang, Noah Davidsohn, Karolina Chwalek, Shao-Ming Zhou, Yuancheng Lu, Qiurui Zeng, Daniel L. Vera, Vadim N. Gladyshev, Michael B. Schultz, Steve Horvath, Xiao Tian, George M. Church, Emma Hoffmann, Chen Wang, Luis A. Rajman, Meredith S Gregory-Ksander, Ekaterina Korobkina, Zhigang He
مصطلحات موضوعية: 0303 health sciences, Regeneration (biology), 030302 biochemistry & molecular biology, Biology, Retinal ganglion, Cell biology, 03 medical and health sciences, medicine.anatomical_structure, SOX2, Ageing, DNA methylation, medicine, Epigenetics, Axon, Reprogramming, 030304 developmental biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1aa13f06cd1ee4d4508a57d3d466f9d
https://doi.org/10.1101/710210 -
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المؤلفون: Brendan O'Connell, Daniel L. Vera, Mital Bhakta, Jae-Hyun Yang, Luis A. Rajman, Benjamin A. Garcia, Marco Blanchette, Elizabeth M. Munding, Philipp Oberdoerffer, Andreas R. Pfenning, Motoshi Hayano, Shelley L. Berger, Patrick Griffin, Richard E. Green, Michael L. Creswell, Qiao Su, Stuart J. Shankland, John K. Apostolides, Jeffrey W. Pippin, Chun Xu, Margarita Meer, Elias L. Salfati, Zhixun Dou, David A. Sinclair, Vadim N. Gladyshev
المصدر: SSRN Electronic Journal.
مصطلحات موضوعية: Genome instability, 0303 health sciences, biology, DNA damage, Sterility, Identity (social science), Budding yeast, Cell identity, Cell biology, Chromatin, 03 medical and health sciences, 0302 clinical medicine, Histone, Dna breaks, DNA methylation, biology.protein, Epigenetics, 030217 neurology & neurosurgery, 030304 developmental biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7597452fb80121cebe55d5b32e138691
https://doi.org/10.2139/ssrn.3461780 -
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المؤلفون: Karolina Chwalek, Luis A. Rajman, David A. Sinclair
مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Physiology, Longevity, Cell Biology, Nicotinamide adenine dinucleotide, CD38, NAD, Redox, Article, Cell biology, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, PARP1, Enzyme, chemistry, Nicotinamide riboside, Animals, Humans, NAD+ kinase, Energy Metabolism, Molecular Biology, Nicotinamide mononucleotide, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ebc62593e116308680c81cc58da0b5
https://europepmc.org/articles/PMC6342515/ -
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المؤلفون: James P. White, Rafael de Cabo, Magdalene K. Montgomery, David A. Sinclair, Ana P. Gomes, Eric L. Bell, Evi M. Mercken, Christiane D. Wrann, Javid Moslehi, Basil P. Hubbard, Luis A. Rajman, Carlos M. Palmeira, Nathan L. Price, Anabela P. Rolo, João S. Teodoro, Alvin J. Y. Ling, Nigel Turner
المصدر: Cell. 155(7):1624-1638
مصطلحات موضوعية: Aging, Oxidative phosphorylation, AMP-Activated Protein Kinases, Mitochondrion, Biology, Article, Oxidative Phosphorylation, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Sirtuin 1, medicine, Animals, Glucose homeostasis, Muscle, Skeletal, 030304 developmental biology, Nicotinamide mononucleotide, Cell Nucleus, 0303 health sciences, Biochemistry, Genetics and Molecular Biology(all), Hypoxia-Inducible Factor 1, alpha Subunit, NAD, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Mitochondria, Cell nucleus, medicine.anatomical_structure, chemistry, Biochemistry, Nicotinamide riboside, biology.protein, NAD+ kinase, Reactive Oxygen Species, 030217 neurology & neurosurgery, Transcription Factors
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المؤلفون: Jun, Li, Michael S, Bonkowski, Sébastien, Moniot, Dapeng, Zhang, Basil P, Hubbard, Alvin J Y, Ling, Luis A, Rajman, Bo, Qin, Zhenkun, Lou, Vera, Gorbunova, L, Aravind, Clemens, Steegborn, David A, Sinclair
المصدر: Science (New York, N.Y.). 355(6331)
مصطلحات موضوعية: Models, Molecular, Paraquat, Aging, DNA Repair, Poly (ADP-Ribose) Polymerase-1, Fibroblasts, NAD, Radiation Tolerance, Article, Mice, HEK293 Cells, Neoplasms, Sequence Homology, Nucleic Acid, Animals, Humans, Protein Interaction Domains and Motifs, RNA, Small Interfering, Conserved Sequence, Adaptor Proteins, Signal Transducing, DNA Damage
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::1296bc09d7105ebb7275474178c5f72d
https://pubmed.ncbi.nlm.nih.gov/28336669