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1دورية أكاديمية
المؤلفون: Dimitrios Evangelopoulos, Gareth A. Prosser, Angela Rodgers, Belinda M. Dagg, Bhagwati Khatri, Mei Mei Ho, Maximiliano G. Gutierrez, Teresa Cortes, Luiz Pedro S. de Carvalho
المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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2دورية أكاديمية
المؤلفون: Sarah Batson, Cesira de Chiara, Vita Majce, Adrian J. Lloyd, Stanislav Gobec, Dean Rea, Vilmos Fülöp, Christopher W. Thoroughgood, Katie J. Simmons, Christopher G. Dowson, Colin W. G. Fishwick, Luiz Pedro S. de Carvalho, David I. Roper
المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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3دورية أكاديمية
المؤلفون: João P. Pisco, Cesira de Chiara, Kamila J. Pacholarz, Acely Garza-Garcia, Roksana W. Ogrodowicz, Philip A. Walker, Perdita E. Barran, Stephen J. Smerdon, Luiz Pedro S. de Carvalho
المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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المؤلفون: Catherine B, Hubert, Luiz Pedro S, de Carvalho
المصدر: Methods in enzymology. 665
مصطلحات موضوعية: Bacteria, Metabolome, Metabolomics, Metabolic Networks and Pathways
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المؤلفون: Catherine B. Hubert, Luiz Pedro S. de Carvalho
المصدر: Methods in Enzymology ISBN: 9780323952675
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8ff66290ad62f3dade31d811abfa2b54
https://doi.org/10.1016/bs.mie.2021.12.001 -
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المؤلفون: Martyn Frederickson, Irwin R. Selvam, Dimitrios Evangelopoulos, Kirsty J. McLean, Mona M. Katariya, Richard B. Tunnicliffe, Bethany Campbell, Madeline E. Kavanagh, Sitthivut Charoensutthivarakul, Richard T. Blankley, Colin W. Levy, Luiz Pedro S. de Carvalho, David Leys, Andrew W. Munro, Anthony G. Coyne, Chris Abell
المساهمون: Coyne, Anthony [0000-0003-0205-5630], Abell, Chris [0000-0001-9174-1987], Apollo - University of Cambridge Repository
المصدر: Frederickson, M, Selvam, I R, Evangelopoulos, D, McLean, K J, Katariya, M M, Tunnicliffe, R B, Campbell, B, Kavanagh, M E, Charoensutthivarakul, S, Blankley, R T, Levy, C W, de Carvalho, L P S, Leys, D, Munro, A W, Coyne, A G & Abell, C 2022, ' A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening approach (XP screen) ', European Journal of Medicinal Chemistry, vol. 230, 114105 . https://doi.org/10.1016/j.ejmech.2022.114105
مصطلحات موضوعية: Pharmacology, Drug discovery, X-Rays, Organic Chemistry, Antitubercular Agents, CYP121, Infectious Disease, Mycobacterium tuberculosis, General Medicine, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, Biochemistry & Proteomics, Metabolism, Ecology,Evolution & Ethology, Manchester Institute of Biotechnology, Drug Design, Drug Discovery, Humans, Tuberculosis, Genetics & Genomics, X-ray crystallography, Structural Biology & Biophysics, Computational & Systems Biology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d9c2705833bafc4766f5cadaceb345
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المؤلفون: Luiz Pedro S. de Carvalho, Laura Masino, Holly L. Douglas, Argyrides Argyrou, Jonathan Bailey
المصدر: Biochemistry
مصطلحات موضوعية: S-Adenosylmethionine, Biochemistry, Pyrophosphate, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Adenosine Triphosphate, Methionine, Enzyme Stability, medicine, Humans, 030304 developmental biology, 0303 health sciences, Cycloleucine, Isothermal titration calorimetry, Methionine Adenosyltransferase, Phosphate, Adenosine, Recombinant Proteins, Kinetics, chemistry, Product inhibition, 030220 oncology & carcinogenesis, Biophysics, Transmethylation, medicine.drug
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8
المؤلفون: Cesira de Chiara, Gareth A. Prosser, Geoff Kelly, Luiz Pedro S. de Carvalho, Acely Garza-Garcia, Miha Homšak, Edward W. Tate, Andrew Purkiss, Holly L. Douglas
المصدر: Nature chemical biology
مصطلحات موضوعية: Protein Conformation, D-cycloserine, Isomerase, Cofactor, Article, Mycobacterium tuberculosis, Ligases, 03 medical and health sciences, chemistry.chemical_compound, Bacterial Proteins, Alanine racemase, Oximes, Escherichia coli, Amino Acid Sequence, Molecular Biology, Pyridoxal, Antibiotics, Antitubercular, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, DNA ligase, Alanine, Binding Sites, biology, 030302 biochemistry & molecular biology, Alanine Racemase, Cell Biology, Isoxazoles, biology.organism_classification, Recombinant Proteins, 3. Good health, Enzyme, Biochemistry, chemistry, Cycloserine, biology.protein, Protein Binding
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المؤلفون: Luiz Pedro S. de Carvalho, Steven Howell, Mercedes Monteleone, Stuart Horswell, Brian C. VanderVen, Warwick J. Britton, Ambrosius P. Snijders, Agnese Serafini, Acely Garza-Garcia, Lendl Tan, Minh-Duy Phan, Mark A. Schembri, Maximiliano G. Gutierrez, Christine R Montague, Nicholas P. West, Deborah M. Hunt, Daniel J. Greenwood
المصدر: Molecular Microbiology
مصطلحات موضوعية: Glyoxylate cycle, Citrate (si)-Synthase, Microbiology, Mycobacterium tuberculosis, 03 medical and health sciences, chemistry.chemical_compound, Metabolomics, Bacterial Proteins, Biosynthesis, Lipid droplet, Pyruvic Acid, Tuberculosis, Citrates, Lactic Acid, Molecular Biology, Research Articles, 030304 developmental biology, 0303 health sciences, biology, Fatty acid metabolism, 030306 microbiology, Fatty Acids, Glyoxylates, Gene Expression Regulation, Bacterial, Metabolism, biology.organism_classification, 3. Good health, Gluconeogenesis, chemistry, Biochemistry, Acyl Coenzyme A, Research Article
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المؤلفون: Jiri Vlach, Jamil S. Saad, Luiz Pedro S. de Carvalho, Olga Danilchanka, Acely Garza-Garcia, Doreen William, Uday Tak, Michael Niederweis
المصدر: Journal of Biological Chemistry. 294:3024-3036
مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, 030102 biochemistry & molecular biology, biology, Nicotinamide, Mutagenesis, Cell Biology, musculoskeletal system, medicine.disease_cause, Biochemistry, Cofactor, 3. Good health, 03 medical and health sciences, chemistry.chemical_compound, Cytosol, 030104 developmental biology, Enzyme, chemistry, medicine, biology.protein, NAD+ kinase, Enzyme kinetics, Molecular Biology, Escherichia coli
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::28b8329d57cedd8b740913463f8af62b
https://doi.org/10.1074/jbc.ra118.005832
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