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1دورية أكاديمية
المؤلفون: Sharon M. Campbell, Joseph DeBartolo, James R. Apgar, Lydia Mosyak, Virginie McManus, Sonia Beyer, Eric M. Bennett, Matthew Lambert, Orla Cunningham
المصدر: mAbs, Vol 13, Iss 1 (2021)
مصطلحات موضوعية: Antibody nonspecificity, developability, IL-21R, deselection, optimization, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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المؤلفون: Virginie McManus, James R. Apgar, Sonia Beyer, Sharon M. Campbell, Orla Cunningham, Matthew Allister Lambert, Joseph DeBartolo, Eric M. Bennett, Lydia Mosyak
المصدر: mAbs
article-version (VoR) Version of Recordمصطلحات موضوعية: Protein Conformation, Immunology, Mutagenesis (molecular biology technique), Computational biology, Protein Engineering, Antibody nonspecificity, DNA sequencing, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, Drug Stability, In vivo, Antibody Specificity, Report, developability, Immunology and Allergy, Humans, 030304 developmental biology, 0303 health sciences, biology, Protein Stability, High-Throughput Nucleotide Sequencing, Interleukin-21 Receptor alpha Subunit, Antibodies, Neutralizing, HEK293 Cells, Mutagenesis, 030220 oncology & carcinogenesis, Drug Design, biology.protein, Computer-Aided Design, Antibody, deselection, Platform development, optimization, Reports, IL-21R
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المؤلفون: Hovhannes J. Gukasyan, David Paterson, Karen J. Klamerus, Kush Lalwani, Ronald A. Schachar, Anand Giddabasappa, Lydia Mosyak, Rand Norberg, Kay D. Rittenhouse, Jeetendra Eswaraka
المصدر: Experimental Eye Research. 145:373-379
مصطلحات موضوعية: Male, 0301 basic medicine, Platelet-derived growth factor, Axitinib, genetic structures, Tyrosine-kinase inhibitor, Neovascularization, chemistry.chemical_compound, 0302 clinical medicine, Wet age-related macular degeneration, Medicine, 3D co-culture model, Fluorescein Angiography, In vitro angiogenesis, biology, Imidazoles, Immunohistochemistry, Sensory Systems, Choroidal neovascularization, Intravitreal Injections, Rat choroidal neovascularization, medicine.symptom, Platelet-derived growth factor receptor, medicine.drug, medicine.medical_specialty, Indazoles, medicine.drug_class, 03 medical and health sciences, Cellular and Molecular Neuroscience, In vivo, Internal medicine, Small molecule receptor tyrosine kinase inhibitor, Animals, Humans, Protein Kinase Inhibitors, Aged, Cell Proliferation, business.industry, Endothelial Cells, Mesenchymal Stem Cells, Macular degeneration, medicine.disease, Choroidal Neovascularization, eye diseases, Rats, Disease Models, Animal, Ophthalmology, 030104 developmental biology, Endocrinology, chemistry, 030221 ophthalmology & optometry, biology.protein, Cancer research, sense organs, Pericytes, business
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المؤلفون: William S. Somers, Lydia Mosyak, Orla Cunningham, Chao Tu, Amy Tam, Brian J. Fennell, Joel Bard, Edward R. Lavallie, Mark Stahl, Wayne Stochaj, Laura Lin, William J.J. Finlay, Virginie Terraube
المصدر: Journal of Biological Chemistry. 291:1267-1276
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Protein Conformation, Recombinant Fusion Proteins, Mutant, Antibody Affinity, Mutagenesis (molecular biology technique), chemical and pharmacologic phenomena, Antigen-Antibody Complex, Computational biology, Complementarity determining region, Protein aggregation, medicine.disease_cause, Biochemistry, law.invention, Protein Aggregates, 03 medical and health sciences, Protein structure, X-Ray Diffraction, Antibody Specificity, law, medicine, Humans, Molecular Biology, Biological Products, Mutation, Protein Stability, Chemistry, Cell Biology, respiratory system, Chemokine CXCL13, Complementarity Determining Regions, Recombinant Proteins, Kinetics, 030104 developmental biology, Amino Acid Substitution, Solubility, Protein Structure and Folding, Recombinant DNA, Binding Sites, Antibody, Single-Chain Antibodies
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261c02617c3e30bb3256d94b8c8a3cef
https://doi.org/10.1074/jbc.m115.688010 -
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المؤلفون: Renee Ramsey, Sri Laxmanan, Orla Cunningham, Lydia Mosyak, Brian J. Fennell, Joel Bard, Steven P. Braithwaite, Bénédicte Autin, Chao Tu, Christopher John Corcoran, Anne S. Klein, Edward R. Lavallie, Leeying Wu, Wei Cao, Eugenia Kouranova, Heather H. Shih, Anthony J. Milici, William J.J. Finlay, Janet E. Paulsen, Jo Ann Dumin, Deirdre Ní Shúilleabháin, Matthew Allister Lambert, Maya Arai, Mostafa Ait-Zahra, Davinder Gill
المصدر: Journal of Biological Chemistry. 287:44425-44434
مصطلحات موضوعية: Molecular Sequence Data, Tau protein, Mice, Transgenic, tau Proteins, Peptide, Complementarity determining region, Biochemistry, Antibodies, Epitope, Epitopes, Mice, Alzheimer Disease, Animals, Humans, Amino Acid Sequence, Phosphorylation, Molecular Biology, chemistry.chemical_classification, biology, Phosphopeptide, Brain, Cell Biology, Structural biology, chemistry, Immunoglobulin G, Protein Structure and Folding, biology.protein, Antibody, Chickens
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e527a805643d52b9e49f16ee3c80cdac
https://doi.org/10.1074/jbc.m112.415935 -
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المؤلفون: Robert John Steffan, Lydia Mosyak, Richard C. Winneker, Susan Chippari, Lisa Borges-Marcucci, Amy Eckert, William Jay Moore, Zhang Xu, Edward Martin Matelan, Christopher C. Chadwick, Mark A. Ashwell, William Ronald Solvibile, Steven J. Adelman, Thomas Kenney, Eugene John Trybulski, Douglas C. Harnish
المصدر: Current Topics in Medicinal Chemistry. 6:103-111
مصطلحات موضوعية: Chemokine, Estrogen receptor, Inflammation, Pharmacology, Ligands, Structure-Activity Relationship, Drug Discovery, medicine, Humans, Estrogen receptor beta, chemistry.chemical_classification, Molecular Structure, biology, Chemistry, Ligand, Cell adhesion molecule, Anti-Inflammatory Agents, Non-Steroidal, General Medicine, Enzyme, Receptors, Estrogen, Drug development, Chronic Disease, biology.protein, Pyrazoles, medicine.symptom
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed82e50c368a115db9d8021ee12b246
https://doi.org/10.2174/156802606775270279 -
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المؤلفون: Laura Lin, Mark Stahl, William S. Somers, Karen C. Carroll, Zhang-Bao Xu, Pranab K. Chanda, KeWei Wang, Karl Malakian, Robert Scannevin, Flora Jow, Meggin Taylor, Lydia Mosyak, Wade Edris, Alan H. Katz, Jennifer Megules, Stephane Olland, Kenneth J. Rhodes, Mark R. Bowlby, Weixin Xu, Qiang Lu, David C. Kopsco
المصدر: Neuron. 41:587-598
مصطلحات موضوعية: Models, Molecular, Patch-Clamp Techniques, Potassium Channels, Neuroscience(all), Crystallography, X-Ray, Cell Line, Membrane Potentials, Calcium-binding protein, Animals, Humans, Amino Acid Sequence, K channels, Binding Sites, Chemistry, General Neuroscience, Calcium-Binding Proteins, Cell Membrane, Mutagenesis, Kv Channel-Interacting Proteins, Structural framework, Protein Structure, Tertiary, Transport protein, N-terminus, Protein Subunits, Shal Potassium Channels, Terminal (electronics), Biochemistry, Potassium Channels, Voltage-Gated, Mutagenesis, Site-Directed, Oocytes, cardiovascular system, Biophysics, Protein Binding
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