المؤلفون: Sharon R Lewin, Rachel D. Pascoe, Rémi Fromentin, Paul U. Cameron, Ashanti Dantanarayana, Celine Gubser, Thomas A Rasmussen, Lydie Trautman, Ajantha Solomon, Christopher Chiu, Vanessa A. Evans, James H McMahon, Judy Chang, Nicolas Chomont

المصدر: Chiu, C Y, Chang, J J, Dantanarayana, A I, Solomon, A, Evans, V A, Pascoe, R, Gubser, C, Trautman, L, Fromentin, R, Chomont, N, McMahon, J H, Cameron, P U, Rasmussen, T A & Lewin, S R 2022, ' Combination Immune Checkpoint Blockade Enhances IL-2 and CD107a Production from HIV-Specific T Cells Ex Vivo in People Living with HIV on Antiretroviral Therapy ', Journal of Immunology, vol. 208, no. 1, pp. 54-62 . https://doi.org/10.4049/jimmunol.2100367
J Immunol

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, Lysosomal-Associated Membrane Protein 1/metabolism, HIV Infections, T-Cell Antigen Receptor Specificity, CD8-Positive T-Lymphocytes, Lymphocyte Activation, Anti-Retroviral Agents/therapeutic use, Antigens, Viral/immunology, Immunology and Allergy, Medicine, CTLA-4 Antigen, Receptors, Immunologic, Cytotoxicity, Antigens, Viral, Immune Checkpoint Inhibitors, Cells, Cultured, Drug Synergism, Middle Aged, Lymphocyte Activation Gene 3 Protein, medicine.anatomical_structure, Anti-Retroviral Agents, CD4-Positive T-Lymphocytes/immunology, Drug Therapy, Combination, Interleukin-1/metabolism, Adult, T cell, Immunology, Antigens, CD/immunology, HIV Infections/drug therapy, CTLA-4 Antigen/immunology, CD8-Positive T-Lymphocytes/immunology, Peripheral blood mononuclear cell, Article, HIV Long-Term Survivors, Immune system, TIGIT, Antigens, CD, Lysosomal-Associated Membrane Protein 1, HIV-1/physiology, Humans, business.industry, Immune Checkpoint Inhibitors/therapeutic use, Immune checkpoint, Receptors, Immunologic/immunology, Cancer research, HIV-1, business, Ex vivo, CD8, Interleukin-1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1bbff23e6545b23bc265b80b828ee9c
https://pure.au.dk/portal/da/publications/combination-immune-checkpoint-blockade-enhances-il2-and-cd107a-production-from-hivspecific-t-cells-ex-vivo-in-people-living-with-hiv-on-antiretroviral-therapy(b1e04674-c9d9-4b2c-85ec-4cc0210d139f).html

المؤلفون: Elly Verbeek, Hinrich W. H. Göhlmann, Marion Crauwels, Dieder Moechars, Frans W. Verheijen, Rachel Schot, Rudi D'Hooge, Nathalie Van Acker, Stijn Stroobants, An De Bondt, Grazia M.S. Mancini, Luc Andries, Guy Daneels, Michiel W.M. Knaapen, Ilse Goris

المساهمون: Neurology

المصدر: Experimental Neurology. 291:106-119

مصطلحات موضوعية: 0301 basic medicine, Pathology, Lysosomal-Associated Membrane Protein 1/metabolism, Developmental Disabilities, Intermediate Filaments/metabolism, Intermediate Filaments, Organic Anion Transporters, Leukoencephalopathy, Myelin, 0302 clinical medicine, Symporters/deficiency, Leukoencephalopathies, Medicine(all), Symporters, Mental Disorders, Age Factors, Brain, Gene Expression Regulation, Developmental, Glial Fibrillary Acidic Protein/metabolism, Sialic Acid Storage Disease, medicine.anatomical_structure, Developmental Disabilities/etiology, Neurology, Mental Disorders/etiology, medicine.medical_specialty, Leukoencephalopathies/complications, mice, Hindbrain, Mice, Transgenic, Biology, 03 medical and health sciences, Developmental Neuroscience, Lysosomal-Associated Membrane Protein 1, Glial Fibrillary Acidic Protein, medicine, Animals, Brain/metabolism, CNS hypomyelination, Progressive leukoencephalopathy, Lineage markers, medicine.disease, Oligodendrocyte, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Animals, Newborn, Immunology, Sialic Acid Storage Disease/complications, Organic Anion Transporters/deficiency, Gene Expression Regulation, Developmental/genetics, 030217 neurology & neurosurgery

وصف الملف: Print-Electronic; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470d22f55e736a062f60e44e37c917fd

المؤلفون: Chihiro Ohba, Akgun Olmez Turker, Burcu Albuz, Fabio Benfenati, Kazuhiro Ogata, Naomichi Matsumoto, Ashley L. Siniard, Keri Ramsey, Alessandro Esposito, Davide Mei, Carla Marini, Mitsuhiro Kato, Chris Balak, C Nur Semerci Gündüz, Renzo Guerrini, Vinodh Narayanan, Keiko Yanagihara, Elisa Belmonte, Mitsuko Nakashima, Valerio Conti, Masaaki Shiina, Anna Fassio, Nobuhiko Okamoto, Luca Maragliano, Hirotomo Saitsu

المصدر: Brain

مصطلحات موضوعية: Male, hippocampus, Endocytic cycle, autophagosome, cell organelle, Vesicular Transport Proteins, whole exome sequencing, stereospecificity, developmental epileptic encephalopathy, Proton transport, v type proton transporting adenosine triphosphatase, genetics, nuclear magnetic resonance imaging, Child, Cells, Cultured, Regulation of gene expression, Neurons, Mutation, clinical article, Adolescent, Animals, Brain/diagnostic imaging, Brain Diseases/complications/*genetics/pathology, Cohort Studies, Epilepsy/complications/*genetics/pathology, Female, Gene Expression Regulation/genetics, HEK293 Cells, Humans, Lysosomal-Associated Membrane Protein 1/metabolism, Lysosomes/metabolism/pathology, Models, Molecular, Mutation/*genetics, Neurons/metabolism/pathology/ultrastructure, Rats, Synapses/metabolism/pathology, Vacuolar Proton-Translocating ATPases/*ge, Brain, gene expression regulation, cohort analysis, Cell biology, developmental delay, priority journal, protein stability, sequence alignment, brain nerve cell, nerve cell, ATP6V1A protein, human, mutational analysis, Vacuolar Proton-Translocating ATPases, EEG abnormality, neurite outgrowth, phenotype, diagnostic imaging, embryo, complication, Article, animal tissue, febrile convulsion, 03 medical and health sciences, early endosome antigen 1, lysosomes, Exome Sequencing, V-ATPase, case report, human, protein expression, Loss function, developmental encephalopathy, Epilepsy, catalysis, human cell, proton transporting adenosine triphosphatase, functional connectivity, school child, 030104 developmental biology, proton transporting adenosine triphosphate synthase, Synapses, Neurology (clinical), proton transport, molecular model, 0301 basic medicine, medicine.disease_cause, fluorescence microscopy, synapse, protein folding, homeostasis, rat, animal, neurite elongation, brain disease, Brain Diseases, Chemistry, intractable epilepsy, ultrastructure, unclassified drug, female, medicine.anatomical_structure, v-ATPase, HEK293 cell line, lysosome, quadriplegia, ATP6V1A gene, amino acid substitution, Neurite, HEK293T cell line, Lysosomal-Associated Membrane Protein 1, Lysosome, medicine, controlled study, gene, developmental epileptic encephalopathy, lysosomes, neurite elongation, synapse, v-ATPase, Neurology (clinical), lymphoblast, cell culture, model, nonhuman, missense mutation, vesicular transport protein, Original Articles, heterozygote, clinical feature, Gene Expression Regulation, lysosome associated membrane protein 1, gene expression, pathology, metabolism

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0005eadc19e8dd317cbba9f60a0d1691
https://pubmed.ncbi.nlm.nih.gov/29668857

المؤلفون: Cedric Bandelier, Laure Valloton, Pierre-Yves Martin, Yannick Avila, Leo Buhler, Sylvie Ferrari-Lacraz, Casimir de Rham, Giuseppe Pantaleo, Manuel Pascual, Karine Hadaya, Jean Villard

المصدر: Clinical Immunology, Vol. 137, No 2 (2010) pp. 250-260

مصطلحات موضوعية: Cytotoxicity, Immunologic, Graft Rejection, Male, Interleukin-12/pharmacology, Lysosomal-Associated Membrane Protein 1/metabolism, medicine.medical_treatment, Kidney Transplantation/*immunology, Lymphocytes/cytology/drug effects, NK Cell Lectin-Like Receptor Subfamily C/metabolism, Receptors, KIR, Antilymphocyte Serum/*pharmacology/therapeutic use, Immunology and Allergy, Interferon gamma, Lymphocytes, ddc:616, Aged, 80 and over, ddc:617, Immunosuppression, Middle Aged, Interleukin-12, Killer Cells, Natural, medicine.anatomical_structure, Interleukin 12, Receptors, Natural Killer Cell, Female, Rabbits, Receptors, KIR/metabolism, NK Cell Lectin-Like Receptor Subfamily C, medicine.drug, Adult, Immunology, Biology, Receptors, Natural Cytotoxicity Triggering, Cytotoxicity, Immunologic/immunology, Natural killer cell, Interferon-gamma, Young Adult, Lysosomal-Associated Membrane Protein 1, Receptors, Natural Cytotoxicity Triggering/metabolism, medicine, Animals, Humans, Lymphocyte Count, Antilymphocyte Serum, Aged, Interferon-gamma/metabolism, Graft Rejection/prevention & control, Killer Cells, Natural/cytology/drug effects/*immunology/*metabolism, Receptors, Natural Killer Cell/*metabolism, Cytotoxicity Tests, Immunologic, NKG2D, Kidney Transplantation, Anti-thymocyte globulin, Transplantation, K562 Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329cd6d2645ab6405f6a63b67664ffda
https://doi.org/10.1016/j.clim.2010.07.004