المؤلفون: Huber, K., Mestres-Arenas, A., Fajas, L., Leal-Esteban, L.C.

المصدر: The FEBS journal, vol. 288, no. 12, pp. 3813-3833

مصطلحات موضوعية: Adaptation, Physiological, Animals, Cell Cycle/drug effects, Cell Cycle/genetics, Cells, Cultured, Cyclin-Dependent Kinase Inhibitor Proteins/genetics, Cyclin-Dependent Kinase Inhibitor Proteins/metabolism, Cyclin-Dependent Kinases/antagonists & inhibitors, Cyclin-Dependent Kinases/genetics, Cyclin-Dependent Kinases/metabolism, Cyclins/genetics, Cyclins/metabolism, E2F Transcription Factors/genetics, E2F Transcription Factors/metabolism, Endosomes/drug effects, Endosomes/metabolism, Gene Expression Regulation, Humans, Lysosomes/drug effects, Lysosomes/metabolism, Mitochondria/drug effects, Mitochondria/metabolism, Nutritive Value/physiology, Protein Kinase Inhibitors/pharmacology, Retinoblastoma Protein/genetics, Retinoblastoma Protein/metabolism, Saccharomyces cerevisiae/drug effects, Saccharomyces cerevisiae/growth & development, Saccharomyces cerevisiae/metabolism, Signal Transduction, cell cycle regulators, cell growth, endolysosomes, metabolism, mitochondria

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1900::7d0b37299c19a72cb95cc727ce46215e
https://serval.unil.ch/resource/serval:BIB_71F450E7C4FC.P001/REF.pdf

المؤلفون: Laskar, Amit

مصطلحات موضوعية: Apoptosis, Cathepsin L, Contrast Media, Edetic Acid -- analogs and derivatives, Ferric Compounds, Ferritins, Hydroxycholesterols -- pharmacology, Lysosomes -- drug effects, Lysosomes -- metabolism, Magnetite Nanoparticles, Mitochondria -- drug effects, Mitochondria -- metabolism, Oxidative Stress, Pyridoxal Phosphate -- analogs and derivatives

URL الوصول: http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-92003

Degree: Diss. (sammanfattning) Linköping : Linköpings universitet, 2013

المؤلفون: Ivan Kodvanj, Jan Homolak

المصدر: International Journal of Antimicrobial Agents

مصطلحات موضوعية: 0301 basic medicine, Coronavirus Infections / virology, Drug repurposing, Betacoronavirus / drug effects, Virus Replication, Bioinformatics, pharmacology_toxicology, 0302 clinical medicine, Chloroquine, Endosome, Lysosomes / drug effects, COVID-19, Lysosomotropic agents, Antiviral, Pharmacology (medical), 030212 general & internal medicine, General Medicine, Drug repositioning, medicine.anatomical_structure, Infectious Diseases, Pneumonia, Viral / virology, Antiviral Agents / pharmacology, Virus Replication / drug effects, medicine.symptom, Coronavirus Infections, Betacoronavirus / physiology, medicine.drug, Microbiology (medical), Coronavirus disease 2019 (COVID-19), Pneumonia, Viral, 030106 microbiology, Context (language use), Antiviral Agents, Article, Betacoronavirus, 03 medical and health sciences, Lysosome, medicine, Humans, Pandemics, Fluoxetine, Coronavirus Infections / drug therapy, SARS-CoV-2, business.industry, Drug Repositioning, Clinical trial, Mechanism of action, Pneumonia, Viral / drug therapy, Cancer research, Lysosomes, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e7bb1ddbb65747a64d1a314ae27dc3

المؤلفون: Bauke V. Schomakers, Nicole N. van der Wel, Rebecca L. McIntyre, Georges E. Janssens, Riekelt H. Houtkooper, Henk van der Veen, Ruedi Aebersold, Jiayi Lan, Pallas Yao, Alyson W. MacInnes, Evan G. Williams, Michel van Weeghel, William B. Mair, Yasmine J. Liu

المساهمون: Graduate School, Laboratory for General Clinical Chemistry, AGEM - Endocrinology, metabolism and nutrition, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Medical Biology, ANS - Cellular & Molecular Mechanisms, AGEM - Inborn errors of metabolism, Laboratory Genetic Metabolic Diseases, ACS - Diabetes & metabolism, APH - Aging & Later Life, ACS - Heart failure & arrhythmias

المصدر: Journal of cell biology, 219(6):e201907067.. Rockefeller University Press
The Journal of Cell Biology
The Journal of Cell Biology, 219 (6)
Journal of Cell Biology

مصطلحات موضوعية: Proteomics, Autophagosomes/drug effects, Mitochondrial translation, Mitochondrion, Mitochondrial Dynamics, 0302 clinical medicine, RNA interference, Signal Transduction/drug effects, Basic Helix-Loop-Helix Transcription Factors, Spotlight, 0303 health sciences, Microscopy, Reproduction, Longevity/genetics, Cell biology, Mitochondria, RNA Interference, Genetics & genetic processes [F10] [Life sciences], Génétique & processus génétiques [F10] [Sciences du vivant], Signal Transduction, Protein Biosynthesis/drug effects, Lysosomes/drug effects, Longevity, Biology, Electron, 03 medical and health sciences, Caenorhabditis elegans Proteins/genetics, Microscopy, Electron, Transmission, Mitochondrial unfolded protein response, Unfolded Protein Response/drug effects, Animals, Transmission, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Transcription factor, Reproduction/physiology, 030304 developmental biology, Caenorhabditis elegans/metabolism, Basic Helix-Loop-Helix Transcription Factors/genetics, Autophagy, Autophagosomes, Cell Biology, Mitochondrial Dynamics/drug effects, Gene Ontology, Protein Biosynthesis, Unfolded Protein Response, TFEB, Mitochondria/genetics, Lysosomes, 030217 neurology & neurosurgery, Biogenesis

وصف الملف: application/pdf; application/application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf92aa06dfb07ea906a8e597121f5502
http://orbilu.uni.lu/handle/10993/48043

المؤلفون: Yu, Zhengquan

مصطلحات موضوعية: Lysosomes -- metabolism, Lysosomes -- drug effects, Protons, Apoptosis -- drug effects, Necrosis -- drug effects, Iron chelating agents -- pharmacology, Iron -- chemistry, Ironxmetabolism, Oxidative stress -- drug effects, Amifostine -- pharmacology, Aldehydes -- pharmacology

URL الوصول: http://www.bibl.liu.se/liupubl/disp/disp2003/med808s.pdf

Degree: Diss. (sammanfattning) Linköping : Univ., 2003

المؤلفون: Zhao, Ming

مصطلحات موضوعية: Apoptosis -- drug effects, Apoptosis -- metabolism, Lysosomes -- drug effects, Mitochondria -- drug effects, Mitochondria -- metabolism, Oxidative stress, Phospholipases A -- pharmacology, Oxidants -- pharmacology, Proto-oncogene proteins c-bcl-2 -- metabolism, Proto-oncogene proteins c-bcl-2 -- physiology

URL الوصول: http://www.bibl.liu.se/liupubl/disp/disp2002/med747s.pdf

Degree: Diss. (sammanfattning) Linköping : Univ., 2002

المؤلفون: Peter L. Hordijk, Igor Kovacevic, Saskia Scheij, Emma C. L. Cook, Noam Zelcer, Jessica K. Nelson, Anke Loregger, Huib Ovaa, Marten A. Hoeksema

المساهمون: Graduate School, Medical Biochemistry, ACS - Diabetes & metabolism, ACS - Atherosclerosis & ischemic syndromes, AGEM - Endocrinology, metabolism and nutrition, Amsterdam Gastroenterology Endocrinology Metabolism, Landsteiner Laboratory, AII - Inflammatory diseases, Physiology, ICaR - Ischemia and repair

المصدر: Journal of biological chemistry, 291(9), 4813-4825. American Society for Biochemistry and Molecular Biology Inc.
Journal of Biological Chemistry, 291(9), 4813-4825. American Society for Biochemistry and Molecular Biology Inc.
Nelson, J K, Cook, E C L, Loregger, A, Hoeksema, M A, Scheij, S, Kovacevic, I, Hordijk, P L, Ovaa, H & Zelcer, N 2016, ' Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake ', Journal of Biological Chemistry, vol. 291, no. 9, pp. 4813-4825 . https://doi.org/10.1074/jbc.M115.698688

مصطلحات موضوعية: 0301 basic medicine, Ubiquitin-Specific Proteases/antagonists & inhibitors, Transcription, Genetic, LDL/metabolism, Recombinant Proteins/chemistry, Biochemistry, Transcription, Genetic/drug effects, Mice, Ubiquitin, Genes, Reporter, Orphan Nuclear Receptors/genetics, Receptors, Transcriptional regulation, Receptors, LDL/genetics, Enzyme Inhibitors, Promoter Regions, Genetic, Ubiquitin-Protein Ligases/chemistry, Cells, Cultured, Liver X Receptors, Enzyme Inhibitors/pharmacology, Cultured, biology, Ubiquitination/drug effects, Recombinant Fusion Proteins/chemistry, Orphan Nuclear Receptors, Lipids, Recombinant Proteins, Ubiquitin ligase, Absorption, Physiological, Lipoproteins, LDL, Physiological/drug effects, lipids (amino acids, peptides, and proteins), Ubiquitin-Specific Proteases, Transcription, Absorption, Physiological/drug effects, Lysosomes/drug effects, Recombinant Fusion Proteins, Ubiquitin-Protein Ligases, Cells, Lipoproteins, Human Umbilical Vein Endothelial Cells/cytology, LDL/genetics, Absorption, Cell Line, Promoter Regions, 03 medical and health sciences, Lipoproteins, LDL/metabolism, Human Umbilical Vein Endothelial Cells, Animals, Humans, Liver X receptor, Molecular Biology, Post-transcriptional regulation, Transcription factor, Promoter Regions, Genetic/drug effects, Reporter, Genetic/drug effects, Ubiquitination, Proteolysis/drug effects, Cell Biology, 030104 developmental biology, Nuclear receptor, Receptors, LDL, Amino Acid Substitution, Genes, LDL receptor, Proteolysis, Mutation, biology.protein, Lysosomes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cedf0913ddcfb2603c43cc631340d66d
https://doi.org/10.1074/jbc.m115.698688

المؤلفون: Salvatore Valitutti, Olivier Hermine, Carle Paul, Michel Lavit, Pol André Apoil, Michel Laroche, Camille Laurent, Cristina Bulai Livideanu, Eric Espinosa

المساهمون: Centre de Recherches en Cancérologie de Toulouse (CRCT), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Unité différenciation épidermique et auto-immunité rhumatoïde (UDEAR), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Toulouse [Toulouse], Institut Universitaire du Cancer de Toulouse - Oncopole (IUCT Oncopole - UMR 1037), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Laboratoire de Pharmacocinétique et de Toxicologie clinique [Toulouse], Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut Fédératif de Biologie (IFB) - Hôpital Purpan, Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse]-CHU Toulouse [Toulouse]-Hôpital Purpan [Toulouse]

المصدر: Clinical Immunology
Clinical Immunology, Elsevier, 2018, 194, pp.75-79. ⟨10.1016/j.clim.2018.07.004⟩

مصطلحات موضوعية: Male, 0301 basic medicine, Mast cell activation syndrome, [SDV]Life Sciences [q-bio], Immunology, Tryptase, 03 medical and health sciences, Therapeutic approach, Lysosome, MESH: Lysosomes / drug effects, Humans, Immunology and Allergy, Medicine, MESH: Inflammation Mediators / therapeutic use, MESH: Humans, MESH: Middle Aged, biology, business.industry, Mast cell activation, Cutaneous Mastocytosis, MESH: Mastocytosis / drug therapy, MESH: Mast Cells / drug effects, Hydroxychloroquine, Middle Aged, Mast cell, MESH: Hydroxychloroquine / therapeutic use, MESH: Male, 3. Good health, 030104 developmental biology, medicine.anatomical_structure, biology.protein, Cancer research, Mast cells, Inflammation Mediators, medicine.symptom, Lysosomes, business, Mast cell activation diseases, Mastocytosis, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d403c91c3d746af7b3d007496109814
https://hal-univ-tlse3.archives-ouvertes.fr/hal-03284513

المؤلفون: Zdolsek, Johann

مصطلحات موضوعية: Lysosomes: drug effects

المؤلفون: Mingeot-Leclercq, M P, Brasseur, Robert, Schanck, A

المصدر: Journal of Toxicology and Environmental Health, 44 (3), 263 - 300 (1995-03)

مصطلحات موضوعية: Aminoglycosides, Anti-Bacterial Agents, Liposomes, Membrane Lipids, Phospholipids, Phospholipases, Animals, Anti-Bacterial Agents/metabolism, Anti-Bacterial Agents/toxicity, Binding Sites, Cell Death/drug effects, Cell Membrane/drug effects, Cell Membrane/metabolism, Cell Membrane Permeability/drug effects, Fluorescence Polarization, Hair Cells, Auditory/drug effects, Hair Cells, Auditory/pathology, Kidney Tubules, Proximal/drug effects, Kidney Tubules, Proximal/pathology, Lysosomes/drug effects, Lysosomes/enzymology, Magnetic Resonance Spectroscopy, Membrane Lipids/metabolism, Phospholipases/antagonists & inhibitors, Phospholipids/metabolism, Rats, Toxicology, Pollution, Human health sciences, Pharmacy, pharmacology & toxicology, Sciences de la santé humaine, Pharmacie, pharmacologie & toxicologie

Relation: http://www.tandfonline.com/doi/pdf/10.1080/15287399509531960; urn:issn:0098-4108

URL الوصول: https://orbi.uliege.be/handle/2268/313003