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1
المؤلفون: P. J. Eddershaw, Peter S. Goldfarb, M. H. Tarbit, David F.V. Lewis
المصدر: Xenobiotica. 27:319-340
مصطلحات موضوعية: Models, Molecular, Subfamily, Molecular model, Cytochrome, Stereochemistry, Health, Toxicology and Mutagenesis, Molecular Sequence Data, Sequence alignment, Computational biology, Toxicology, digestive system, Biochemistry, Homology (biology), Mixed Function Oxygenases, Bacterial Proteins, Cytochrome P-450 Enzyme System, Amino Acid Sequence, skin and connective tissue diseases, Alleles, NADPH-Ferrihemoprotein Reductase, Pharmacology, chemistry.chemical_classification, Polymorphism, Genetic, Sequence Homology, Amino Acid, biology, Active site, Cytochrome P450, General Medicine, Ondansetron, Isoenzymes, Enzyme, Cytochrome P-450 CYP2D6, chemistry, Mutagenesis, Site-Directed, biology.protein, Serotonin Antagonists
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2
المؤلفون: D. F. V. Lewis, P. J. Eddershaw, P. S. Goldfarb, M. H. Tarbit
المصدر: Xenobiotica. 26:1067-1086
مصطلحات موضوعية: Pharmacology, Health, Toxicology and Mutagenesis, General Medicine, Toxicology, Biochemistry
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3
المؤلفون: M. H. Tarbit, David F.V. Lewis, P. J. Eddershaw, Brian G. Lake, Michael G. Bird, Maurice Dickins, Peter S. Goldfarb
المصدر: Xenobiotica; the fate of foreign compounds in biological systems. 30(1)
مصطلحات موضوعية: Models, Molecular, Molecular model, Stereochemistry, Health, Toxicology and Mutagenesis, Molecular Sequence Data, Toxicology, Crystallography, X-Ray, Biochemistry, Isozyme, Homology (biology), Mixed Function Oxygenases, Substrate Specificity, Structure-Activity Relationship, Bacterial Proteins, Cytochrome P-450 Enzyme System, Cytochrome P-450 Enzyme Inhibitors, Humans, Amino Acid Sequence, Enzyme Inhibitors, NADPH-Ferrihemoprotein Reductase, Pharmacology, chemistry.chemical_classification, Binding Sites, biology, Sequence Homology, Amino Acid, Active site, Cytochrome P450, Cytochrome P-450 CYP2E1, General Medicine, Templates, Genetic, Amino acid, Cytochrome P-450 CYP2E1 Inhibitors, Isoenzymes, Models, Structural, Enzyme, chemistry, Docking (molecular), biology.protein
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4
المؤلفون: D F, Lewis, A, Wiseman, M H, Tarbit
المصدر: Journal of enzyme inhibition. 14(3)
مصطلحات موضوعية: Azoles, Models, Molecular, Antifungal Agents, Sequence Homology, Amino Acid, Molecular Sequence Data, Saccharomyces cerevisiae, Mixed Function Oxygenases, Fungal Proteins, Lanosterol, Sterol 14-Demethylase, Structure-Activity Relationship, Ketoconazole, Bacterial Proteins, Cytochrome P-450 Enzyme System, Catalytic Domain, Cytochrome P-450 Enzyme Inhibitors, Computer Simulation, Amino Acid Sequence, Oxidoreductases, NADPH-Ferrihemoprotein Reductase
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5
المؤلفون: David F.V. Lewis, Maurice Dickins, P. J. Eddershaw, Brian G. Lake, Peter S. Goldfarb, M. H. Tarbit
المصدر: Xenobiotica; the fate of foreign compounds in biological systems. 29(4)
مصطلحات موضوعية: Gene isoform, Models, Molecular, Subfamily, Stereochemistry, Health, Toxicology and Mutagenesis, Molecular Sequence Data, Crystal structure, Toxicology, Crystallography, X-Ray, Biochemistry, Homology (biology), Mixed Function Oxygenases, Substrate Specificity, Structure-Activity Relationship, Bacterial Proteins, Cytochrome P-450 Enzyme System, Cytochrome b5, Animals, Humans, Amino Acid Sequence, Binding site, NADPH-Ferrihemoprotein Reductase, Pharmacology, Binding Sites, biology, L-Lactate Dehydrogenase, Sequence Homology, Amino Acid, Active site, Regioselectivity, Oxidoreductases, N-Demethylating, General Medicine, Hydrogen-Ion Concentration, Rats, Cytochrome P-450 CYP2B6, Kinetics, Cytochrome P-450 CYP2B1, Steroid Hydroxylases, biology.protein, Mutagenesis, Site-Directed, Aryl Hydrocarbon Hydroxylases, L-Lactate Dehydrogenase (Cytochrome), Rabbits
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6
المؤلفون: David F.V. Lewis, Peter S. Goldfarb, P. J. Eddershaw, M. H. Tarbit, Maurice Dickins, R. J. Weaver
المصدر: Xenobiotica; the fate of foreign compounds in biological systems. 28(3)
مصطلحات موضوعية: Models, Molecular, Subfamily, Molecular model, Stereochemistry, Health, Toxicology and Mutagenesis, Molecular Sequence Data, Sequence alignment, Toxicology, Biochemistry, Isozyme, Mixed Function Oxygenases, Substrate Specificity, Cytochrome P-450 Enzyme System, Species Specificity, Humans, Amino Acid Sequence, Site-directed mutagenesis, Peptide sequence, Cytochrome P-450 CYP2C9, Pharmacology, chemistry.chemical_classification, biology, Active site, General Medicine, Cytochrome P-450 CYP2C19, Isoenzymes, Enzyme, chemistry, Steroid 16-alpha-Hydroxylase, Steroid Hydroxylases, biology.protein, Mutagenesis, Site-Directed, Aryl Hydrocarbon Hydroxylases, Sequence Alignment
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المؤلفون: M. H. Tarbit, Peter S. Goldfarb, P. J. Eddershaw, David F.V. Lewis
المصدر: Xenobiotica; the fate of foreign compounds in biological systems. 26(10)
مصطلحات موضوعية: Models, Molecular, Molecular model, Stereochemistry, Health, Toxicology and Mutagenesis, Molecular Sequence Data, Toxicology, Biochemistry, Isozyme, Homology (biology), Mixed Function Oxygenases, Substrate Specificity, Bacterial Proteins, Cytochrome P-450 Enzyme System, Electrochemistry, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme Inhibitors, Humans, Amino Acid Sequence, NADPH-Ferrihemoprotein Reductase, Pharmacology, chemistry.chemical_classification, Binding Sites, biology, Active site, Cytochrome P450, General Medicine, Metabolism, Templates, Genetic, Amino acid, Enzyme, chemistry, biology.protein, Sequence Alignment, Protein Binding
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المؤلفون: G R, Manchee, P J, Eddershaw, L E, Ranshaw, D, Herriott, G R, Park, M K, Bayliss, M H, Tarbit
المصدر: Drug metabolism and disposition: the biological fate of chemicals. 24(5)
مصطلحات موضوعية: Molecular Structure, Midazolam, Adrenergic beta-Agonists, Quinidine, Recombinant Proteins, Isoenzymes, Ketoconazole, Cytochrome P-450 Enzyme System, Theophylline, Sulfaphenazole, Disulfiram, Microsomes, Liver, Cytochrome P-450 Enzyme Inhibitors, Humans, Albuterol, Oxidation-Reduction, Salmeterol Xinafoate, Biomarkers, Chromatography, High Pressure Liquid
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::1314a3f0e6ca97e77d325eb647a37c5f
https://pubmed.ncbi.nlm.nih.gov/8723736 -
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المؤلفون: C M, Dixon, P V, Colthup, C J, Serabjit-Singh, B M, Kerr, C C, Boehlert, G R, Park, M H, Tarbit
المصدر: Drug metabolism and disposition: the biological fate of chemicals. 23(11)
مصطلحات موضوعية: Male, In Vitro Techniques, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Transfection, Ondansetron, Isoenzymes, Cytochrome P-450 Enzyme System, Microsomes, Liver, Tumor Cells, Cultured, Humans, Female, Serotonin Antagonists, Genetic Engineering, Chromatography, High Pressure Liquid
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::1f794e06341e0c3d4d6c7123b18dc3fe
https://pubmed.ncbi.nlm.nih.gov/8591723 -
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المؤلفون: H L, Bomont, M H, Tarbit, M J, Humphrey, J B, Houston
المصدر: Pharmaceutical research. 11(7)
مصطلحات موضوعية: Azoles, Male, Rats, Sprague-Dawley, Antifungal Agents, Binding Sites, Ketoconazole, Cytochrome P-450 Enzyme System, Microsomes, Liver, Animals, Triazoles, Rats
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