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1دورية أكاديمية
المؤلفون: Alexander Rouvinski, Pablo Guardado-Calvo, Giovanna Barba-Spaeth, Stéphane Duquerroy, Marie-Christine Vaney, Carlos M. Kikuti, M. Erika Navarro Sanchez, Wanwisa Dejnirattisai, Wiyada Wongwiwat
المصدر: Nature, Nature. 520(7545):109-113
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المؤلفون: Joseph J.B. Cockburn, A. Urvoas, Nickolas Fretes, Hugues Bedouelle, Isabelle Staropoli, Lark L. Coffey, Carlos M. Kikuti, Fernando Arenzana Seisdedos, Félix A. Rey, M. Erika Navarro Sanchez
المصدر: Structure. 20:303-314
مصطلحات موضوعية: biology, medicine.drug_class, viruses, virus diseases, biochemical phenomena, metabolism, and nutrition, Dengue virus, Monoclonal antibody, medicine.disease_cause, Virology, Epitope, Neutralization, Microbiology, Structural Biology, Immunity, Monoclonal, biology.protein, medicine, Viral disease, Antibody, Molecular Biology
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المؤلفون: Leonid V. Chernomordik, Félix A. Rey, Stéphane Duquerroy, Ana P. Goncalvez, M. Erika Navarro Sanchez, Philippe Dussart, Elena Zaitseva, Carlos M. Kikuti, Joseph J.B. Cockburn, Enrico A. Stura, Ching-Juh Lai
المصدر: The EMBO Journal. 31:767-779
مصطلحات موضوعية: 0303 health sciences, General Immunology and Microbiology, 030306 microbiology, medicine.drug_class, viruses, General Neuroscience, Biology, Dengue virus, medicine.disease, Monoclonal antibody, medicine.disease_cause, Virology, General Biochemistry, Genetics and Molecular Biology, Epitope, 3. Good health, Dengue fever, 03 medical and health sciences, Viral envelope, Viral entry, medicine, Viral structural protein, Antibody-dependent enhancement, Molecular Biology, 030304 developmental biology
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المؤلفون: Stéphane Duquerroy, Christine Girard-Blanc, William Shepard, Wiyada Wongwiwat, Giovanna Barba-Spaeth, Stéphane Petres, Félix A. Rey, Pablo Guardado-Calvo, Ahmed Haouz, Juthathip Mongkolsapaya, M. Erika Navarro Sanchez, Carlos M. Kikuti, Wanwisa Dejnirattisai, Philippe Dussart, Fernando Arenzana-Seisdedos, Alexander Rouvinski, Marie-Christine Vaney, Philippe Desprès, Gavin R. Screaton
المساهمون: Virologie Structurale - Structural Virology, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11), Imperial College London, Protéopole, Synchrotron SOLEIL (SSOLEIL), Centre National de la Recherche Scientifique (CNRS), Interactions Moléculaires Flavivirus-Hôtes, Institut Pasteur [Paris] (IP), Pathogénie Virale - Viral Pathogenesis, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur de la Guyane, Réseau International des Instituts Pasteur (RIIP), Mahidol University [Bangkok], his work was made possible by a Pediatrics Dengue Vaccine Initiative grant to F.A.R., allowing the set up of a production facility of recombinant DENV sE. The co-crystallization with the bnAbs was done with European Union funding (DenFree consortium) to F.A.R. and G.R.S./J.M. F.A.R. acknowledges support from Insitut Pasteur, from the French Government’s ‘Investissements d’Avenir’ program: Laboratoire d’Excellence ‘Integrative Biology of Emerging Infectious Diseases’ (grant number ANR-10-LABX-62-IBEID) and the CNRS. G.S.R. and J.M. were supported by the Medical Research Council, UK, the Wellcome Trust, UK, the National Institute for Health Research Biomedical Research Centre, Funding Scheme. G.R.S. is a Wellcome Trust Senior investigator. We thank staffs at beam lines PROXIMA-1 and PROXIMA-2 at the SOLEIL synchrotron (St Aubin, France) and ID23-2 and ID29 at the European Synchrotron Radiation Facility (Grenoble, France)., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), Tortosa, Pablo, Integrative Biology of Emerging Infectious Diseases - - IBEID2010 - ANR-10-LABX-0062 - LABX - VALID, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris], Pathogénie Virale, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Medical Research Council (MRC), Wellcome Trust, Commission of the European Communities, Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur [Paris]
المصدر: Nature
Nature, 2015, 520 (7545), pp.109-113. ⟨10.1038/nature14130⟩
Nature, Nature Publishing Group, 2015, 520 (7545), pp.109-113. ⟨10.1038/nature14130⟩مصطلحات موضوعية: Serotype, MECHANISM, Models, Molecular, MONOCLONAL-ANTIBODY, FAB FRAGMENTS, Protein Conformation, viruses, DROSOPHILA S2 CELLS, Dengue virus, medicine.disease_cause, Antibodies, Viral, Crystallography, X-Ray, Epitope, Dengue fever, Epitopes, FUSION, Viral Envelope Proteins, Virus maturation, [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology, 0303 health sciences, Multidisciplinary, REFINEMENT, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], BORNE ENCEPHALITIS-VIRUS, ENVELOPE GLYCOPROTEIN, 3. Good health, Multidisciplinary Sciences, Flavivirus, IMMATURE FLAVIVIRUS PARTICLES, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Science & Technology - Other Topics, [SDV.IMM]Life Sciences [q-bio]/Immunology, [SDV.IMM] Life Sciences [q-bio]/Immunology, General Science & Technology, [SDV.BBM.BS] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Molecular Sequence Data, Biology, Cross Reactions, Virus, MATURATION, 03 medical and health sciences, Species Specificity, MD Multidisciplinary, medicine, Humans, Antibody-dependent enhancement, 030304 developmental biology, Science & Technology, 030306 microbiology, Dengue Virus, medicine.disease, biology.organism_classification, Virology, Antibodies, Neutralizing, Solubility, Mutation, Protein Multimerization
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