المؤلفون: Zhang BB; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Zhengzhou, China., Zhao YL; Department of Cardiology, The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, China., Lu YY; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Zhengzhou, China., Shen JH; Department of Electrocardiogram, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Li HY; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Zhengzhou, China., Zhang HX; Institute of Chronic Non-Communicable Diseases, Henan Provincial Center for Disease Control and Prevention, Zhengzhou, China., Yu XY; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Zhengzhou, China., Zhang WC; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Zhengzhou, China., Li G; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Zhengzhou, China., Han ZY; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Zhengzhou, China. hzy91@163.com., Guo S; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Zhengzhou, China. fccguos@edu.zzu.com., Zhang XT; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Zhengzhou, China. zbbgzr@126.com.; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China. zbbgzr@126.com.

المصدر: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Sep 11; Vol. 22 (1), pp. 438. Date of Electronic Publication: 2024 Sep 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE

مواضيع طبية MeSH: Cardiomegaly*/genetics , Cardiomegaly*/metabolism , Cardiomegaly*/pathology , Membrane Proteins*/metabolism , Membrane Proteins*/genetics , Myocytes, Cardiac*/metabolism , Myocytes, Cardiac*/pathology , MAP Kinase Kinase Kinases*/metabolism , MAP Kinase Kinase Kinases*/genetics, Animals ; Mice ; Mice, Inbred C57BL ; Male ; Disease Progression ; Humans ; Phenylephrine/pharmacology ; MAP Kinase Signaling System ; Oxidative Stress

المؤلفون: Yang A; Department of Systems Biology, School of Life Sciences, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen, 518055, China., Ding Y; Department of Systems Biology, School of Life Sciences, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen, 518055, China., Guo C; Department of Systems Biology, School of Life Sciences, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen, 518055, China., Liu C; Department of Systems Biology, School of Life Sciences, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen, 518055, China., Xiong Z; Department of Systems Biology, School of Life Sciences, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen, 518055, China., Quan M; Department of Systems Biology, School of Life Sciences, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen, 518055, China., Bai P; Department of Systems Biology, School of Life Sciences, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen, 518055, China., Cai R; Department of Systems Biology, School of Life Sciences, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen, 518055, China., Li B; Department of Systems Biology, School of Life Sciences, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen, 518055, China., Li G; Department of Systems Biology, School of Life Sciences, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen, 518055, China., Deng Y; Department of Systems Biology, School of Life Sciences, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen, 518055, China., Wu C; Department of Pathology, School of Medicine and University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, 15260, USA., Sun Y; Department of Systems Biology, School of Life Sciences, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen, 518055, China. suny@sustech.edu.cn.; Research Center for Chemical Biology and Omics Analysis, College of Science, Southern University of Science and Technology, Shenzhen, 518055, China. suny@sustech.edu.cn.

المصدر: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2024 Sep 05; Vol. 81 (1), pp. 385. Date of Electronic Publication: 2024 Sep 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE

مواضيع طبية MeSH: Cisplatin*/adverse effects , Cisplatin*/toxicity , MAP Kinase Kinase Kinases*/metabolism , MAP Kinase Kinase Kinases*/genetics , Signal Transduction*/drug effects , Mice, Knockout*, Animals ; Mice ; Kidney Tubules, Proximal/metabolism ; Kidney Tubules, Proximal/pathology ; Kidney Tubules, Proximal/drug effects ; Humans ; Mice, Inbred C57BL ; Epithelial Cells/metabolism ; Epithelial Cells/drug effects ; Epithelial Cells/pathology ; Ubiquitin-Protein Ligases/metabolism ; Ubiquitin-Protein Ligases/genetics ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/adverse effects ; Kidney Tubules/pathology ; Kidney Tubules/metabolism ; Kidney Tubules/drug effects ; Adaptor Proteins, Signal Transducing

المؤلفون: Ke R; Department of Surgery, Division of Surgical Oncology, University of Illinois at Chicago, Chicago, IL 60612, USA; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL 60607, USA., Kumar S; Department of Surgery, Division of Surgical Oncology, University of Illinois at Chicago, Chicago, IL 60612, USA; University of Illinois Hospital and Health Sciences System Cancer Center, University of Illinois at Chicago, Chicago, IL 60612, USA., Singh SK; Department of Surgery, Division of Surgical Oncology, University of Illinois at Chicago, Chicago, IL 60612, USA., Rana A; Department of Surgery, Division of Surgical Oncology, University of Illinois at Chicago, Chicago, IL 60612, USA; University of Illinois Hospital and Health Sciences System Cancer Center, University of Illinois at Chicago, Chicago, IL 60612, USA; Jesse Brown VA Medical Center, Chicago, IL 60612, USA., Rana B; Department of Surgery, Division of Surgical Oncology, University of Illinois at Chicago, Chicago, IL 60612, USA; University of Illinois Hospital and Health Sciences System Cancer Center, University of Illinois at Chicago, Chicago, IL 60612, USA; Jesse Brown VA Medical Center, Chicago, IL 60612, USA. Electronic address: basrana@uic.edu.

المصدر: Biochimica et biophysica acta. Reviews on cancer [Biochim Biophys Acta Rev Cancer] 2024 Sep; Vol. 1879 (5), pp. 189157. Date of Electronic Publication: 2024 Jul 18.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9806362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2561 (Electronic) Linking ISSN: 0304419X NLM ISO Abbreviation: Biochim Biophys Acta Rev Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*/pathology , Neoplasms*/genetics , Neoplasms*/enzymology , Neoplasms*/drug therapy , Mitogen-Activated Protein Kinase Kinase Kinase 11* , MAP Kinase Kinase Kinases*/metabolism , MAP Kinase Kinase Kinases*/genetics, Humans ; Animals ; Apoptosis ; Signal Transduction ; Cell Proliferation

المؤلفون: Ming T; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, PR China., Liu H; Department of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, PR China., Yuan M; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, PR China., Tian J; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, PR China., Fang Q; Department of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, PR China., Liu Y; Department of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, PR China., Kong Q; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, PR China., Wang Q; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, PR China., Song X; Department of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, PR China., Xia Z; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, PR China. Electronic address: xiazhongyuan2005@aliyun.com., Wu X; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, PR China. Electronic address: RM000851@whu.edu.cn.

المصدر: Biochemical pharmacology [Biochem Pharmacol] 2024 Sep; Vol. 227, pp. 116418. Date of Electronic Publication: 2024 Jul 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Intracellular Signaling Peptides and Proteins*/metabolism , Intracellular Signaling Peptides and Proteins*/genetics , MAP Kinase Kinase Kinases*/metabolism , MAP Kinase Kinase Kinases*/genetics , Mice, Inbred C57BL* , NF-kappa B*/metabolism , Sepsis*/metabolism , Ubiquitin-Specific Proteases*/metabolism , Ubiquitin-Specific Proteases*/genetics, Animals ; Humans ; Male ; Mice ; Lung Injury/metabolism ; Lung Injury/etiology ; Lung Injury/prevention & control ; MAP Kinase Signaling System/physiology ; Signal Transduction/physiology ; Ubiquitination

المؤلفون: Hirata Y; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Japan., Nakata Y; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Japan., Komatsu H; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Japan., Kudoh Y; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Japan., Takahashi M; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Japan., Taguchi S; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Japan., Noguchi T; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Japan., Matsuzawa A; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Japan. Electronic address: atsushi.matsuzawa.c6@tohoku.ac.jp.

المصدر: Free radical biology & medicine [Free Radic Biol Med] 2024 Aug 20; Vol. 221, pp. 31-39. Date of Electronic Publication: 2024 May 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis* , MAP Kinase Kinase Kinases*/metabolism , MAP Kinase Kinase Kinases*/genetics , NF-E2-Related Factor 2*/metabolism , NF-E2-Related Factor 2*/genetics , Oxidative Stress* , Reactive Oxygen Species*/metabolism , Ubiquitin-Protein Ligases*/metabolism , Ubiquitin-Protein Ligases*/genetics , Ubiquitination*, Animals ; Humans ; Mice ; Cell Death/genetics ; HEK293 Cells ; Kelch-Like ECH-Associated Protein 1/metabolism ; Kelch-Like ECH-Associated Protein 1/genetics ; Proteolysis ; Signal Transduction

المؤلفون: Sun T; Clinical Laboratory, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou 313000, Zhejiang, PR China; Huzhou Key Laboratory of Precision Medicine Research and Translation for Infectious Diseases, Huzhou Central Hospital, Huzhou 313000, Zhejiang, PR China., Wang F; The Key Laboratory of Molecular Medicine, Huzhou Central Hospital, Huzhou 313000, Zhejiang, PR China., Li J; Clinical Laboratory, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou 313000, Zhejiang, PR China., Wei W; The Key Laboratory of Molecular Medicine, Huzhou Central Hospital, Huzhou 313000, Zhejiang, PR China., Wang Y; Clinical Laboratory, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou 313000, Zhejiang, PR China., Tong Z; Huzhou Key Laboratory of Precision Medicine Research and Translation for Infectious Diseases, Huzhou Central Hospital, Huzhou 313000, Zhejiang, PR China; Department of Infectious Diseases, Huzhou Central Hospital, Huzhou 313000, Zhejiang, PR China. Electronic address: hztongzhaowei@163.com., Zou W; Clinical Laboratory, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou 313000, Zhejiang, PR China; Huzhou Key Laboratory of Precision Medicine Research and Translation for Infectious Diseases, Huzhou Central Hospital, Huzhou 313000, Zhejiang, PR China; Clinical Laboratory, Huzhou Central Hospital, Affiliated Central Hospital of Huzhou University, Huzhou 313000, Zhejiang, PR China. Electronic address: zxyyjykzwh@126.com.

المصدر: International immunopharmacology [Int Immunopharmacol] 2024 Aug 20; Vol. 137, pp. 112510. Date of Electronic Publication: 2024 Jun 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Lipopolysaccharides*/immunology , Acute Lung Injury*/chemically induced , Acute Lung Injury*/genetics , Acute Lung Injury*/immunology , MAP Kinase Kinase Kinases*/metabolism , MAP Kinase Kinase Kinases*/genetics , NF-kappa B*/metabolism, Animals ; Humans ; Mice ; Mice, Inbred C57BL ; Male ; Cytokines/metabolism ; Cytokines/genetics ; RAW 264.7 Cells ; Inflammation/genetics ; Inflammation/chemically induced ; MAP Kinase Signaling System/drug effects ; Signal Transduction ; Disease Models, Animal

المؤلفون: Yu H; College of Veterinary Medicine, Institute of Comparative Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu Province, China., Sun Y; College of Veterinary Medicine, Institute of Comparative Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu Province, China., Zhang J; College of Veterinary Medicine, Institute of Comparative Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu Province, China., Zhang W; College of Veterinary Medicine, Institute of Comparative Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu Province, China., Liu W; College of Veterinary Medicine, Institute of Comparative Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu Province, China., Liu P; College of Veterinary Medicine, Institute of Comparative Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu Province, China., Liu K; Joint International Research Laboratory of Agriculture and Agri-Product Safety of Ministry of Education of China, Yangzhou, 225009, Jiangsu Province, China., Sun J; College of Veterinary Medicine, Institute of Comparative Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu Province, China., Liang H; Department of General Surgery, Affiliated Hospital of Yangzhou University, Yangzhou, 225009, Jiangsu Province, China., Zhang P; College of Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu Province, China., Wang X; Animal Infectious Disease Laboratory, College of Veterinary Medicine, Yangzhou University, Yangzhou, 225009, China., Liu X; Animal Infectious Disease Laboratory, College of Veterinary Medicine, Yangzhou University, Yangzhou, 225009, China., Xu X; College of Veterinary Medicine, Institute of Comparative Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu Province, China. xxl@yzu.edu.cn.; Joint International Research Laboratory of Agriculture and Agri-Product Safety of Ministry of Education of China, Yangzhou, 225009, Jiangsu Province, China. xxl@yzu.edu.cn.; Jiangsu Coinnovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou University, Yangzhou, 225009, Jiangsu Province, China. xxl@yzu.edu.cn.

المصدر: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2024 Aug 19; Vol. 81 (1), pp. 355. Date of Electronic Publication: 2024 Aug 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE

مواضيع طبية MeSH: Immunity, Innate* , Deubiquitinating Enzyme CYLD*/metabolism , Deubiquitinating Enzyme CYLD*/genetics , Caspase 8*/metabolism , Caspase 8*/genetics , MAP Kinase Kinase Kinases*/metabolism , MAP Kinase Kinase Kinases*/genetics , MAP Kinase Kinase Kinases*/immunology , Ubiquitination* , Influenza A virus*/immunology , DEAD Box Protein 58*/metabolism , DEAD Box Protein 58*/genetics , DEAD Box Protein 58*/immunology , Influenza, Human*/immunology , Influenza, Human*/virology, Humans ; A549 Cells ; Animals ; Signal Transduction/immunology ; Receptors, Immunologic

المؤلفون: Rinotas V; Institute for Fundamental Biomedical Research, Biomedical Sciences Research Center (BSRC) 'Alexander Fleming', Vari, Greece., Iliaki K; Institute for Fundamental Biomedical Research, Biomedical Sciences Research Center (BSRC) 'Alexander Fleming', Vari, Greece., Pavlidi L; Institute for Fundamental Biomedical Research, Biomedical Sciences Research Center (BSRC) 'Alexander Fleming', Vari, Greece., Meletakos T; Institute for Fundamental Biomedical Research, Biomedical Sciences Research Center (BSRC) 'Alexander Fleming', Vari, Greece., Mosialos G; School of Biology, Aristotle University of Thessaloniki, Thessaloniki, Macedonia, Greece., Armaka M; Institute for Fundamental Biomedical Research, Biomedical Sciences Research Center (BSRC) 'Alexander Fleming', Vari, Greece. armaka@fleming.gr.

المصدر: Cell death & disease [Cell Death Dis] 2024 Aug 09; Vol. 15 (8), pp. 584. Date of Electronic Publication: 2024 Aug 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

مواضيع طبية MeSH: Fibroblasts*/metabolism , Fibroblasts*/pathology , Deubiquitinating Enzyme CYLD*/metabolism , Deubiquitinating Enzyme CYLD*/genetics , MAP Kinase Kinase Kinases*/metabolism , MAP Kinase Kinase Kinases*/genetics , Signal Transduction* , Synovial Membrane*/metabolism , Synovial Membrane*/pathology , I-kappa B Kinase*/metabolism , I-kappa B Kinase*/genetics , Arthritis, Rheumatoid*/metabolism , Arthritis, Rheumatoid*/pathology , Arthritis, Rheumatoid*/genetics, Animals ; Mice ; Tumor Necrosis Factor-alpha/metabolism ; Tumor Necrosis Factor-alpha/pharmacology ; Humans ; NF-kappa B/metabolism ; Mice, Inbred C57BL ; Mice, Knockout

المؤلفون: Vinnakota JM; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs-University, Freiburg, Germany., Biavasco F; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Schwabenland M; Institute for Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany., Chhatbar C; Institute for Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany., Adams RC; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Erny D; Institute for Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany., Duquesne S; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., El Khawanky N; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Medicine III, School of Medicine, Technical University of Munich, Munich, Germany.; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technical University of Munich, Munich, Germany., Schmidt D; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs-University, Freiburg, Germany., Fetsch V; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs-University, Freiburg, Germany., Zähringer A; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Salié H; Department of Medicine II, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Athanassopoulos D; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Braun LM; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs-University, Freiburg, Germany., Javorniczky NR; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Ho JNHG; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Kierdorf K; Institute for Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany., Marks R; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Wäsch R; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Simonetta F; Division of Hematology, Geneva University Hospitals Geneva, Geneva, Switzerland., Andrieux G; Institute of Medical Bioinformatics and Systems Medicine, Medical Center, University of Freiburg, Freiburg, Germany., Pfeifer D; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Monaco G; Institute for Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany.; Single-Cell Omics Platform Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Institute for Transfusion Medicine and Gene Therapy, Medical Center, University of Freiburg, Freiburg, Germany., Capitini C; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Fry TJ; Center for Cancer and Blood Disorders, Children's Hospital Colorado and Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Blank T; Institute for Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany., Blazar BR; Masonic Cancer Center and Department of Pediatrics, Division of Blood & Marrow Transplant & Cellular Therapy, University of Minnesota, Minneapolis, MN, USA., Wagner E; Department of Hematology and Medical Oncology, Johannes Gutenberg-University Medical Center, Mainz, Germany., Theobald M; Department of Hematology and Medical Oncology, Johannes Gutenberg-University Medical Center, Mainz, Germany., Sommer C; Institute of Neuropathology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany., Stelljes M; Department of Medicine/Hematology and Oncology, University of Münster, Münster, Germany., Reicherts C; Department of Medicine/Hematology and Oncology, University of Münster, Münster, Germany., Jeibmann A; Institute of Neuropathology, University Hospital Münster, Münster, Germany., Schittenhelm J; Department of Neuropathology, Institute of Pathology and Neuropathology, University Hospital Tübingen, Tübingen, Germany., Monoranu CM; Institute of Pathology, University of Würzburg, Würzburg, Germany., Rosenwald A; Institute of Pathology, University of Würzburg, Würzburg, Germany., Kortüm M; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany., Rasche L; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany., Einsele H; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany., Meyer PT; Department of Nuclear Medicine, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Brumberg J; Department of Nuclear Medicine, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Völkl S; Department of Internal Medicine 5, Hematology and Oncology, University Hospital Erlangen, Erlangen, Germany., Mackensen A; Department of Internal Medicine 5, Hematology and Oncology, University Hospital Erlangen, Erlangen, Germany., Coras R; Department of Neuropathology, University Hospital Erlangen, Erlangen, Germany., von Bergwelt-Baildon M; Department of Medicine III, Hematology/Oncology, University Hospital, Ludwig-Maximilians Universität (LMU) Munich, Munich, Germany., Albert NL; German Cancer Consortium (DKTK), Partner Site Munich, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany., Bartos LM; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany., Brendel M; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Holzgreve A; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany., Mack M; Department of Nephrology, University of Regensburg, Regensburg, Germany., Boerries M; Institute of Medical Bioinformatics and Systems Medicine, Medical Center, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK), Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany., Mackall CL; Center for Cancer Cell Therapy, Stanford Cancer Institute, Stanford, CA, USA., Duyster J; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Henneke P; Division of Pediatric Infectious Diseases, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Priller J; Department of Psychiatry, Technischen Universität München (TUM), Munich, Germany., Köhler N; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Centre for Integrative Biological Signalling Studies (CIBSS), University of Freiburg, Freiburg, Germany., Strübing F; Center for Neuropathology and Prion Research, University Hospital, LMU Munich, Munich, Germany., Bengsch B; Department of Medicine II, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK), Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany., Ruella M; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USA.; Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA., Subklewe M; Department of Medicine III, Hematology/Oncology, University Hospital, Ludwig-Maximilians Universität (LMU) Munich, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, German Cancer Research Center (DKFZ), Heidelberg, Germany., von Baumgarten L; German Cancer Consortium (DKTK), Partner Site Munich, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Neuro-Oncology, Department of Neurosurgery, University Hospital, LMU Munich, Munich, Germany., Gill S; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USA.; Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA., Prinz M; Institute for Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany.; Signalling Research Centres BIOSS and Centre for Integrative Biological Signalling Studies (CIBSS), University of Freiburg, Freiburg, Germany., Zeiser R; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany. robert.zeiser@uniklinik-freiburg.de.; German Cancer Consortium (DKTK), Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany. robert.zeiser@uniklinik-freiburg.de.; Signalling Research Centres BIOSS and Centre for Integrative Biological Signalling Studies (CIBSS), University of Freiburg, Freiburg, Germany. robert.zeiser@uniklinik-freiburg.de.

المصدر: Nature cancer [Nat Cancer] 2024 Aug; Vol. 5 (8), pp. 1227-1249. Date of Electronic Publication: 2024 May 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE

مواضيع طبية MeSH: MAP Kinase Kinase Kinases*/metabolism , MAP Kinase Kinase Kinases*/genetics , Microglia*/immunology , Microglia*/metabolism , Neurotoxicity Syndromes*/etiology , Neurotoxicity Syndromes*/immunology , Receptors, Chimeric Antigen*/immunology, Animals ; Mice ; Humans ; Immunotherapy, Adoptive/methods ; p38 Mitogen-Activated Protein Kinases/metabolism ; NF-kappa B/metabolism ; Lymphoma, B-Cell/immunology ; Antigens, CD19/immunology ; Female ; T-Lymphocytes/immunology ; Signal Transduction

المؤلفون: Li B; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, PR China., Hu Y; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, PR China., Chen Y; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, PR China., Liu K; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, PR China., Rong K; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, PR China., Hua Q; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, PR China., Fu S; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, PR China., Yang X; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, PR China., Zhou T; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, PR China., Cheng X; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, PR China., Zhang K; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, PR China. Electronic address: mmc2008@163.com., Zhao J; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, PR China. Electronic address: profzhaojie@126.com.

المصدر: Biochemical pharmacology [Biochem Pharmacol] 2024 Aug; Vol. 226, pp. 116389. Date of Electronic Publication: 2024 Jun 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Intervertebral Disc Degeneration*/drug therapy , Intervertebral Disc Degeneration*/metabolism , MAP Kinase Kinase Kinases*/metabolism , MAP Kinase Kinase Kinases*/antagonists & inhibitors , NF-kappa B*/metabolism , NF-kappa B*/antagonists & inhibitors, Animals ; Humans ; Male ; Rats ; Cells, Cultured ; MAP Kinase Signaling System/drug effects ; MAP Kinase Signaling System/physiology ; Nucleus Pulposus/metabolism ; Nucleus Pulposus/drug effects ; Nucleus Pulposus/pathology ; Protein Binding/physiology ; Protein Binding/drug effects ; Rats, Sprague-Dawley ; Tumor Necrosis Factor-alpha/metabolism