المؤلفون: Markus Furegati, Suzanna Clark, Andreas Marzinzik, Nikolaos Drosos, Emilie Joly, Patrick Schindler, Kristine Venstrom, Yannick Mesrouze, Yoko Oei, Marion Lacaud-Baumlin, Robert Martin Grotzfeld, Lionel Doumampouom-Metoul, Darryl Brynley Jones, Brian Granda, Sandro Nocito, Stephanie Lagasse-Guerro, Etienne Richard, Peiyin Wang, Sylvie Chamoin, Patrick J Rudewicz, Grazia Piizzi, Edwige Beng-Louka, Michael Patrick Dillon, Pavel Fedoseev, Alexei S. Karpov, Isabelle Dacquignies, Patrick Chène, Piotr Martyniuk, Francesca Perruccio, Cristina Nieto-Oberhuber, Marc Lafrance, Enrique Blanco, Mauro Zurini, Edward Lorenzana, William Mallet, Dylan Daniel, Tinya Abrams, Mélanie Velay

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: Drug, biology, 010405 organic chemistry, Chemistry, media_common.quotation_subject, Organic Chemistry, Conjugated system, Pharmacology, 01 natural sciences, Biochemistry, 0104 chemical sciences, body regions, 010404 medicinal & biomolecular chemistry, In vivo, Drug Discovery, biology.protein, Antimitotic Agent, Cleavable linker, Antibody, Linker, media_common, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f60061fe25e069e99abe4fe52a72ca
https://europepmc.org/articles/PMC6912867/

المؤلفون: Marion Lacaud, Tinya Abrams, Piotr Martyniuk, Suzanna Clark, William Mallet, Daniel S. Palacios, Erik Meredith, Cristina Nieto-Oberhuber, Joseph Anthony D'alessio, Mauro Zurini, Grazia Piizzi, Francesca Perruccio, Morvarid Mohseni, Darryl Brynley Jones, Michael Patrick Dillon, Carl Uli Bialucha, Alexei S. Karpov, Thomas G. Gesner, Ankita Raikar

المصدر: ACS Medicinal Chemistry Letters

مصطلحات موضوعية: 0301 basic medicine, Drug, Letter, nicotinamide phosphoribosyltransferase (NAMPT), media_common.quotation_subject, Nicotinamide phosphoribosyltransferase, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, In vivo, Drug Discovery, novel payload, Medicine, Stromal tumor, media_common, biology, business.industry, Organic Chemistry, Payload (computing), body regions, 030104 developmental biology, chemistry, Antibody−drug conjugate (ADC), 030220 oncology & carcinogenesis, Cancer research, biology.protein, Antibody, business, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b35c6417d265cbaaec160e27eb71599
https://doi.org/10.1021/acsmedchemlett.8b00254

المؤلفون: Paul Ramage, Hermann Gram, Mauro Zurini, Jean-Michel Rondeau

المصدر: mAbs. 7:1151-1160

مصطلحات موضوعية: Models, Molecular, medicine.drug_class, Interleukin-1beta, Immunology, Glutamic Acid, Plasma protein binding, Cross Reactions, Antibodies, Monoclonal, Humanized, Crystallography, X-Ray, Monoclonal antibody, Binding, Competitive, Epitope, law.invention, Epitopes, Mice, Species Specificity, Antibody Specificity, law, Report, medicine, Animals, Humans, Immunology and Allergy, Binding site, biology, Antibodies, Monoclonal, Receptors, Interleukin-1, Callithrix, Antibodies, Neutralizing, Virology, Molecular biology, Protein Structure, Tertiary, Rats, Canakinumab, biology.protein, Recombinant DNA, Macaca, Paratope, Rabbits, Antibody, Protein Binding, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e808ab9c1bae8f913f43f26ae22ddf3
https://doi.org/10.1080/19420862.2015.1081323

المؤلفون: Karen Vincent, Mauro Zurini

المصدر: Biotechnology Journal. 7:1444-1450

مصطلحات موضوعية: Drug, Immunoconjugates, medicine.drug_class, Recombinant Fusion Proteins, media_common.quotation_subject, Antibody Affinity, Receptors, Fc, Plasma protein binding, Protein Engineering, Monoclonal antibody, Applied Microbiology and Biotechnology, Immunoglobulin G, Drug Delivery Systems, Antibodies, Bispecific, medicine, Animals, Humans, Receptor, media_common, biology, Chemistry, General Medicine, Hydrogen-Ion Concentration, Fragment crystallizable region, Cell biology, Immunology, biology.protein, Molecular Medicine, Antibody, Protein Binding, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88cdc3e4e0453808bb7ab341cac771f
https://doi.org/10.1002/biot.201200250

المؤلفون: Simone Danner, Gary T. Jennings, Alain Tissot, Anis Mir, Rainer Lüönd, Christoph Wiessner, Martin F. Bachmann, Peter Frey, Laura H. Jacobson, Karl-Heinz Wiederhold, Mauro Zurini, Julia Reichwald, Matthias Staufenbiel, Rainer Ortmann

مصطلحات موضوعية: Genetically modified mouse, Amyloid beta-Peptides, Amyloid, General Neuroscience, Transgene, P3 peptide, Mice, Transgenic, Articles, Human brain, Biology, Pharmacology, medicine.disease, Epitope, Amyloid beta-Protein Precursor, Mice, Treatment Outcome, medicine.anatomical_structure, Alzheimer Disease, In vivo, Immunology, medicine, Animals, Immunotherapy, Alzheimer's disease, Cells, Cultured

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94497b18f542803337150c6084a58b38
https://doi.org/10.1523/jneurosci.0293-11.2011

المؤلفون: Marion Mahnke, Elizabeth Day, Kate Brown, Carol E. Jones, Mauro Zurini, Rita Schmitz, Rachel Moxley, Gabor Jarai

المصدر: European Journal of Pharmaceutical Sciences. 37:264-271

مصطلحات موضوعية: Receptors, CCR7, Chemokine CCL21, Reverse Transcriptase Polymerase Chain Reaction, Molecular Sequence Data, CCL19, Pharmaceutical Science, Chemotaxis, C-C chemokine receptor type 7, Biology, Transfection, Molecular biology, Recombinant Proteins, Calcium in biology, Chemotaxis, Leukocyte, Macaca fascicularis, Chemokine receptor, Immunology, Animals, Chemokine CCL19, Calcium, Amino Acid Sequence, Cloning, Molecular, Lymphocyte homing receptor, Receptor, CCL21

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9998896a1d3e0177448fefb48bcd983
https://doi.org/10.1016/j.ejps.2009.02.013

المؤلفون: Dieter Huesken, Anne Dwertmann, Markus Jaritz, Bruce Beutler, Ulf Korthäuer, Jadranka Koehn, Antal Rot, Mauro Zurini

المصدر: Human Immunology. 68:871-878

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, UNC93B1, Immunology, Antigen presentation, Antigen-Presenting Cells, Endoplasmic Reticulum, Lymphocyte Activation, Major histocompatibility complex, Antigen, Humans, Immunology and Allergy, Antigen-presenting cell, Cells, Cultured, Antigen Presentation, Toll-like receptor, biology, Tumor Necrosis Factor-alpha, Macrophages, Toll-Like Receptors, fungi, Histocompatibility Antigens Class II, Membrane Transport Proteins, Dendritic Cells, General Medicine, Intercellular Adhesion Molecule-1, Acquired immune system, Cell biology, biology.protein, Cytokines, CD8, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43af8d19f7f2fcab844ed34f80d784c9
https://doi.org/10.1016/j.humimm.2007.07.007

المؤلفون: Robin Alec Fairhurst, Joseph D. Fullerton, David Andrew Sandham, Heinz E. Moser, Mauro Zurini, Sandra Haberthuer, Darryl Brynley Jones, Mark Dodds, Julia Hatto, Gurdip Bhalay, Colin Howes, Paul Nicklin, Simon J. Watson, David Farr, Reto Naef, Irene Muller, Andrew Dunstan, Nichola J. Arnold, Nicholas James Devereux, Morris Tweed, Angela Glen, Katharine L. Turner, Beate Leuenberger, David Beer, Sylvie Gomez, Ruth Arnold, Thomas H. Keller, Stephen Paul Collingwood, Sarah Craig

المصدر: Bioorganic & Medicinal Chemistry Letters. 17:2376-2379

مصطلحات موضوعية: Male, Clinical Biochemistry, Biological Availability, Pharmaceutical Science, Biochemistry, Inhibitory Concentration 50, Structure-Activity Relationship, chemistry.chemical_compound, Dogs, Erectile Dysfunction, 3',5'-Cyclic-GMP Phosphodiesterases, In vivo, Drug Discovery, Animals, Humans, Protein Isoforms, Structure–activity relationship, Pharmacokinetics, Enzyme Inhibitors, Molecular Biology, Cyclic Nucleotide Phosphodiesterases, Type 5, chemistry.chemical_classification, Organic Chemistry, Biological activity, Xanthine, In vitro, Bioavailability, Enzyme, chemistry, Xanthines, cGMP-specific phosphodiesterase type 5, Molecular Medicine, Cattle, sense organs

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e21375e8e7ea71d3deb6323b8cc3fb4
https://doi.org/10.1016/j.bmcl.2006.11.019

المؤلفون: HANS FLIRI, GOETZ BAUMANN, ALBERT ENZ, JUERG KALLEN, MARCEL LUYTEN, VINCENT MIKOL, RAO MOVVA, VALERIE QUESNIAUX, MAX SCHREIER, MALCOLM WALKINSHAW, ROLAND WENGER, GERHARD ZENKE, MAURO ZURINI

المصدر: Annals of the New York Academy of Sciences. 696:47-53

مصطلحات موضوعية: chemistry.chemical_classification, Chemistry, General Neuroscience, General Biochemistry, Genetics and Molecular Biology, Cyclosporins, Calcineurin, Enzyme, History and Philosophy of Science, Biochemistry, Cyclosporin a, polycyclic compounds, Structure–activity relationship, Leucine, Peptide sequence, Cyclophilin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d7f4eeba4416946c848ac6bbe945f441
https://doi.org/10.1111/j.1749-6632.1993.tb17141.x

المؤلفون: Reet Tees, Valerie Hungerford, Beate Kleuser, Sabine Geisse, Catherine Wioland, Corinne Wilt, Mauro Zurini, Grazyna Wieczorek, Marc Bigaud, Hermann Gram, Colette Kristofic, Volker Brinkmann, Franco Di Padova, Walter Schuler, Klaus Menninger

المصدر: Transplantation. 77:717-726

مصطلحات موضوعية: Transplantation, Creatinine, Kidney, business.industry, medicine.drug_class, medicine.medical_treatment, chemical and pharmacologic phenomena, medicine.disease, Monoclonal antibody, Autotransplantation, Epitope, chemistry.chemical_compound, surgical procedures, operative, medicine.anatomical_structure, chemistry, Immunology, medicine, business, Acute tubular necrosis, Allotransplantation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::751df3982d86849e037dc8e83027643d
https://doi.org/10.1097/01.tp.0000116563.72763.83