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المؤلفون: Annette Martin, Brigitte Blumen, Stephanie Aicher, Eliane F. Meurs, Penelope Mavromara, Athanasios Kakkanas, Lisette Cohen, Richard Njouom, Gabriela Oprişan
المساهمون: Génétique Moléculaire des Virus à ARN - Molecular Genetics of RNA Viruses (GMV-ARN (UMR_3569 / U-Pasteur_2)), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut Pasteur Hellénique, Réseau International des Instituts Pasteur (RIIP), University of Patras, School of Medicine, Cantacuzino National Medico-Military Institute for Research Development [Bucharest], Cantacuzino Institute [Romania], Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Titu Maiorescu University = Universitatea Titu Maiorescu [Buchares] (UTM), Centre Pasteur du Cameroun, Hépacivirus et Immunité innée, Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Democritus University of Thrace (DUTH), This work was supported in part by an ACIP grant (#A23/2013) from the Institut Pasteur, Paris, France and by the Hellenic Pasteur Institute, Athens, Greece. SA, a PhD student of the University of Patras, School of Health Sciences, Department of Pharmacy, Greece was the recipient of doctoral fellowships from the Calmette and Yersin program and the Virology Department of the Institut Pasteur, and of a young researcher prize from the Fondation des Treilles., The authors gratefully acknowledge: Christine Neuveut (IP Paris) for helpful discussions and for sharing pFOP and pTOP plasmids, Alberto L. Epstein (Université Claude Bernard, Lyon) for sharing pA-EUA2 + lacZ plasmid, Amadou Sall (IP Cambodia) for sharing HCV 1aC isolate, Takaji Wakita (NIID, Tokyo, Japan), Ralf Bartenschlager (Univ. Heidelberg, Germany) and Charles Rice (Rockefeller Univ., New York, USA) for their respective generous gifts of pJFH1, cell-culture adapted pJFH1-2EI3-adapt cDNA, Huh7.5 cells and 1aH77 cDNA, Stephanie Dabo and Matthieu Fritz (IP Paris) for sharing experimental expertise, Sousana Kotanidou and Ksenia Rybkina for technical assistance, Pascal Roux and Anne Danckaert at the Imagopole core facility (IP Paris) for their help in the acquisition and processing of the immunofluorescence images, Sylvie van der Werf (Head of the Unit of Molecular Genetics of RNA Viruses) for her continuous support., Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Scientific Reports
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.11185. ⟨10.1038/s41598-018-29078-2⟩
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports, 2018, 8 (1), pp.11185. ⟨10.1038/s41598-018-29078-2⟩مصطلحات موضوعية: 0301 basic medicine, MESH: Active Transport, Cell Nucleus / genetics, Viral pathogenesis, [SDV]Life Sciences [q-bio], lcsh:Medicine, Hepacivirus, medicine.disease_cause, Malignant transformation, MESH: Genotype, MESH: Wnt Signaling Pathway / genetics, MESH: Hepatitis C / genetics, Transcription (biology), T Cell Transcription Factor 1, MESH: Liver Neoplasms / genetics, lcsh:Science, Wnt Signaling Pathway, beta Catenin, MESH: Cell Proliferation / genetics, Multidisciplinary, Hepatitis C virus, Liver Neoplasms, Wnt signaling pathway, MESH: Carcinoma, Hepatocellular / pathology, MESH: Gene Expression Regulation, Neoplastic, Hepatitis C, 3. Good health, MESH: Hepacivirus / genetics, Gene Expression Regulation, Neoplastic, Cell Transformation, Neoplastic, MESH: HEK293 Cells, Cell signalling, Carcinoma, Hepatocellular, Genotype, Active Transport, Cell Nucleus, MESH: Liver Neoplasms / virology, Biology, Article, 03 medical and health sciences, Downregulation and upregulation, medicine, Humans, Gene, Cell Proliferation, MESH: beta Catenin / genetics, MESH: Liver Neoplasms / pathology, MESH: Humans, lcsh:R, MESH: Carcinoma, Hepatocellular / genetics, MESH: Cell Transformation, Neoplastic / genetics, Molecular biology, MESH: Carcinoma, Hepatocellular / virology, MESH: T Cell Transcription Factor 1 / genetics, 030104 developmental biology, HEK293 Cells, MESH: Hepacivirus / pathogenicity, Catenin, MESH: Hepatitis C / virology, MESH: Hepatitis C / pathology, lcsh:Q
