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المساهمون: Architecture et Dynamique des Macromolécules Biologiques - Architecture and Dynamics of Biological Macromolecules, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Collège doctoral [Sorbonne universités], Sorbonne Université (SU), Chimie biologique épigénétique - Epigenetic Chemical Biology (EpiCBio), Biologie des Bactéries pathogènes à Gram-positif - Biology of Gram-Positive Pathogens, The authors acknowledge a DIM1Health 2019 grant from the Région Ile de France to the project EpiK (coordinated by P.B. Arimondo) for the LCMS equipment., We thank the Crystallogenesis and Crystallography Platform (PF6) of Institut Pasteur for help in crystallization and preliminary crystallographic data collection. We thank Marcel Hollenstein and his group for the use of their HPLC system. We also thank staff from PROXIMA−1 and PROXIMA-2 beamlines for help in data collection and SOLEIL (Saint-Aubin, France) and for provision of synchrotron radiation facilities. We thank Pierre Legrand for discussions regarding the structural aspect of this work, as well as Laurent Debarbieux and his group for discussions regarding phages. We also thank Stéphane Decorps-Declere from the Hub de Bioinformatique et Biostatistique (C3BI, Institut Pasteur) for help with the S-2L genome mapping and its deposition., Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Collège Doctoral, Université Paris Cité (UPCité)-Microbiologie Intégrative et Moléculaire (UMR6047), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.4710. ⟨10.1038/s41467-021-25064-x⟩
Nature Communications, 2021, 12 (1), pp.4710. ⟨10.1038/s41467-021-25064-x⟩
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)مصطلحات موضوعية: DNA, Bacterial, Models, Molecular, Genes, Viral, Protein Conformation, Science, Static Electricity, MESH: Base Pairing, Genome, Viral, Siphoviridae, Crystallography, X-Ray, Article, MESH: Recombinant Proteins, Adenylosuccinate Synthase, Viral Proteins, MESH: Protein Conformation, Escherichia coli, DNA metabolism, MESH: 2-Aminopurine, Bacteriophages, MESH: Adenylosuccinate Synthase, MESH: Siphoviridae, MESH: Bacteriophages, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], 2-Aminopurine, Base Pairing, MESH: Static Electricity, X-ray crystallography, MESH: Genes, Viral, Deoxyadenosines, MESH: Escherichia coli, MESH: Podoviridae, MESH: Deoxyadenosines, Podoviridae, MESH: Crystallography, X-Ray, MESH: Viral Proteins, MESH: DNA, Bacterial, Phosphoric Monoester Hydrolases, Recombinant Proteins, MESH: DNA, Viral, MESH: Metabolic Networks and Pathways, DNA, Viral, MESH: Phosphoric Monoester Hydrolases, MESH: Genome, Viral, Structural biology, Metabolic Networks and Pathways, MESH: Models, Molecular
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المؤلفون: Ahmed Haouz, Simonetta Gribaldo, Pierre Simon Garcia, Najwa Taib, Pascal Röthlisberger, Pierre Alexandre Kaminski, Marion Lagune, Philippe Marliere, Jérôme Loc’h, Dona Sleiman
المساهمون: Biologie des Bactéries pathogènes à Gram-positif - Biology of Gram-Positive Pathogens, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Biologie Evolutive de la Cellule Microbienne - Evolutionary Biology of the Microbial Cell, Adaptation au stress et Métabolisme chez les entérobactéries - Stress adaptation and metabolism in enterobacteria (SAMe), Dynamique structurale des Macromolécules / Structural Dynamics of Macromolecules, Cristallographie (Plateforme) - Crystallography (Platform), Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Chimie bioorganique des acides nucléiques - Bioorganic chemistry of nucleic acids, Génomique métabolique (UMR 8030), Genoscope - Centre national de séquençage [Evry] (GENOSCOPE), Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), D.S. and P.S.G. were supported by an ERASynBio 'TNA episome' and by an ERACoBioTech 'Iron Plug’n Play' fellowship, respectively. S.G. acknowledges funding from the French National Agency for research grant Archaevol (ANR-16-CE02-0005-01). This study was funded from the French government’s Investissement d’Avenir program, Laboratoire d’Excellence Integrative Biology of Emerging Infectious Diseases (grant no. ANR-10-LABX-62-IBEID)., ANR-16-CE02-0005,Arch-Evol,Approches phylogenomiques pour étudier l'origine et évolution des Archées(2016), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS)-Université d'Évry-Val-d'Essonne (UEVE)
المصدر: Science
Science, 2021, 372 (6541), pp.516-520. ⟨10.1126/science.abe6494⟩
Science, American Association for the Advancement of Science, 2021, 372 (6541), pp.516-520. ⟨10.1126/science.abe6494⟩مصطلحات موضوعية: Purine, DNA polymerase, Guanine, Genome, Viral, Viral Nonstructural Proteins, Crystallography, X-Ray, Genome, 03 medical and health sciences, chemistry.chemical_compound, Adenylosuccinate Synthase, MESH: 2-Aminopurine, A-DNA, MESH: Adenylosuccinate Synthase, Bacteriophages, MESH: Bacteriophages, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], MESH: Phylogeny, 2-Aminopurine, Phylogeny, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Multidisciplinary, biology, ATP synthase, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], 030302 biochemistry & molecular biology, MESH: Crystallography, X-Ray, MESH: DNA, Viral, Biosynthetic Pathways, Enzyme, chemistry, Biochemistry, DNA, Viral, biology.protein, MESH: Viral Nonstructural Proteins, MESH: Biosynthetic Pathways, MESH: Genome, Viral, DNA
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8758f0aeb77cb3f97a12f3e0e04478
https://pubmed.ncbi.nlm.nih.gov/33926938