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المؤلفون: Sandrina Kinet, Azra Raza, Lionel Blanc, Naomi Taylor, Erjing Gao, Abdullah Mahmood Ali, Hongxia Yan, Anupama Narla, Julien Papoin, John Hale, Narla Mohandas, Patrick G. Gallagher, Joseph M. Lane, Christopher D. Hillyer
المساهمون: New York Blood Center, Columbia University [New York], Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, The Feinstein Institute for Medical Research, Stanford University School of Medicine [CA, USA], Hospital for Special Surgery, Department of Linguistics, University of Georgia, Athens, GA 30602, USA, Hematopoïèse et Immunothérapie, Institut de Génétique Moléculaire de Montpellier (IGMM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Pediatric Oncology Branch, National Institutes of Health - NIH-Center for Cancer Research - CCR-National Cancer Institute - NCI, Yale University School of Medicine, Columbia University Irving Medical Center (CUIMC)
المصدر: American Journal of Hematology
American Journal of Hematology, Wiley, 2021, 96 (9), pp.1064-1076. ⟨10.1002/ajh.26247⟩
Am J Hematolمصطلحات موضوعية: Ineffective erythropoiesis, MESH: Immunophenotyping, [SDV]Life Sciences [q-bio], Population, CD34, Antigens, CD34, Bone Marrow Cells, MESH: Flow Cytometry, Stem cell factor, Biology, medicine.disease_cause, Article, Immunophenotyping, 03 medical and health sciences, 0302 clinical medicine, Erythroid Cells, Antigens, CD, hemic and lymphatic diseases, MESH: Erythroid Precursor Cells, medicine, Humans, Erythropoiesis, education, MESH: Antigens, CD, Cells, Cultured, Progenitor, Erythroid Precursor Cells, education.field_of_study, MESH: Humans, MESH: Bone Marrow Cells, MESH: Erythropoiesis, Endoglin, MESH: Antigens, CD34, Hematology, MESH: Erythroid Cells, Flow Cytometry, Cell biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Bone marrow, MESH: Endoglin, MESH: Cells, Cultured, 030215 immunology
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المؤلفون: Constance Onfray, Jia Ping Tan, Stéphanie Kilens, Xiaodong Liu, Jose Polo, Laurent David
المساهمون: Centre de Recherche en Transplantation et Immunologie - Center for Research in Transplantation and Translational Immunology (U1064 Inserm - CR2TI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Centre hospitalier universitaire de Nantes (CHU Nantes), Monash University [Clayton], Monash Biomedicine Discovery Institute, Structure fédérative de recherche François Bonamy (SFR François Bonamy), Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche en Santé de l'Université de Nantes (IRS-UN), Le Bihan, Sylvie
المصدر: Human Naïve Pluripotent Stem Cells
Human Naïve Pluripotent Stem Cells, 2416, Springer US, pp.39-51, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-1908-7_4⟩
Methods in Molecular Biology ISBN: 9781071619070مصطلحات موضوعية: MESH: Cell Differentiation, Pluripotent Stem Cells, Yamanaka factors, MESH: Germ Layers, [SDV]Life Sciences [q-bio], Induced Pluripotent Stem Cells, MESH: Induced Pluripotent Stem Cells, MESH: Cellular Reprogramming, Humans, Cells, Cultured, Primed pluripotent stem cells, MESH: Humans, MESH: Octamer Transcription Factor-3 / genetics, Naive pluripotent stem cells, SOXB1 Transcription Factors, Cell Differentiation, Fibroblasts, Cellular Reprogramming, [SDV] Life Sciences [q-bio], MESH: Fibroblasts, embryonic structures, MESH: Pluripotent Stem Cells, MESH: SOXB1 Transcription Factors / genetics, Somatic cell reprogramming, Octamer Transcription Factor-3, Germ Layers, MESH: Cells, Cultured
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b786384ba408f82a9fe3fe75fa6250b
https://pubmed.ncbi.nlm.nih.gov/34870829 -
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المؤلفون: Florence Jeny, Jean-François Bernaudin, Dominique Valeyre, Marianne Kambouchner, Marina Pretolani, Hilario Nunes, Carole Planès, Valérie Besnard
المساهمون: Service de pneumologie [Avicenne], Hôpital Avicenne [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Hypoxie et Poumon : pneumopathologies fibrosantes, modulations ventilatoires et circulatoires (H&P), UFR SMBH-Université Sorbonne Paris Nord, Sorbonne Université - Faculté de Médecine (SU FM), Sorbonne Université (SU), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Physiopathologie et Epidémiologie des Maladies Respiratoires (PHERE (UMR_S_1152 / U1152)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), AP-HP - Hôpital Bichat - Claude Bernard [Paris], Gestionnaire, Hal Sorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)
المصدر: Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology, 2021, 12, pp.719009. ⟨10.3389/fimmu.2021.719009⟩
Frontiers in Immunology, Frontiers, 2021, 12, pp.719009. ⟨10.3389/fimmu.2021.719009⟩مصطلحات موضوعية: MESH: Granuloma, MESH: Sarcoidosis, Pulmonary, MESH: NF-kappa B, hypoxia-inducible factor 1, 0302 clinical medicine, MESH: Hypoxia, Fibrosis, Immunology and Allergy, Macrophage, MESH: Phagocytosis, Hypoxia, Cells, Cultured, Original Research, MESH: Cytokines, 0303 health sciences, Granuloma, NF-kappa B, pulmonary sarcoidosis, MESH: Case-Control Studies, Immunohistochemistry, macrophages, 3. Good health, Phenotype, 030220 oncology & carcinogenesis, MESH: Fibrosis, [SDV.IMM]Life Sciences [q-bio]/Immunology, Cytokines, plasminogen activator inhibitor-1, Tumor necrosis factor alpha, Disease Susceptibility, Inflammation Mediators, medicine.symptom, monocytes, MESH: Cells, Cultured, MESH: Sarcoidosis, [SDV.IMM] Life Sciences [q-bio]/Immunology, Sarcoidosis, Phagocytosis, MESH: Inflammation Mediators, Immunology, MESH: Disease Susceptibility, MESH: Phenotype, MESH: Hypoxia-Inducible Factor 1, alpha Subunit, Proinflammatory cytokine, Fibroblast migration, 03 medical and health sciences, Immune system, Sarcoidosis, Pulmonary, medicine, Humans, 030304 developmental biology, MESH: Humans, business.industry, fibrosis, MESH: Macrophages, MESH: Immunohistochemistry, Fibroblasts, RC581-607, Hypoxia (medical), Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, MESH: Fibroblasts, Case-Control Studies, MESH: Biomarkers, Immunologic diseases. Allergy, business, Biomarkers
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df147dc9914b12fd62b733cb5a1900dc
https://doi.org/10.3389/fimmu.2021.719009 -
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المؤلفون: Sokha Dul, Erik A. Karlsson, Nicholas J. Martin, Jose A. Garcia-Rivera, Heidi Auerswald, Philippe Dussart, Saraden In, Sokhoun Yann
المساهمون: Unité de Virologie / Virology Unit [Phnom Penh], Institut Pasteur du Cambodge, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), US Naval Medical Research Unit n°2, Naval Medical Research Unit Two [Singapore] (NAMRU-2), Naval Medical Research, This work, including that of Dr Auerswald, was supported, in part, by internal funding through Institut Pasteur in Cambodia. Dr Karlsson is supported, in part, by the U.S. Department of Health and Human Services, Office of the Assistant Secretary for Preparedness and Response (Grant No. 1 IDSEP190051-01-00) and through internal funding at Institut Pasteur in Cambodia. The findings and conclusions in this report are those of the authors and do not necessarily represent the official views of the US Department of Health and Human Services. This work was also partially funded and supported by the Armed Forces Health Surveillance, Branch Global Emerging Infections Surveillance Section., We would like to acknowledge the patients, Cambodian Ministry of Health and Cambodian Center for Disease Control, Rapid Response Team members, and the doctors, nurses, and staff of the reference hospitals in Cambodia for their response to the COVID-19 pandemic. We thank all of the technicians and staff at Institut Pasteur du Cambodge in the Virology Unit and at NAMRU-2 in the Molecular Unit involved in this work.
المصدر: Journal of General Virology
Journal of General Virology, Microbiology Society, 2021, 102 (3), pp.001539. ⟨10.1099/jgv.0.001539⟩
The Journal of General Virologyمصطلحات موضوعية: 0301 basic medicine, Hot Temperature, viruses, Sample processing, Biosecurity, heat inactivation, Biosafety, 0302 clinical medicine, MESH: Chlorocebus aethiops, Chlorocebus aethiops, MESH: COVID-19, Medicine, MESH: Animals, 030212 general & internal medicine, Cells, Cultured, 0303 health sciences, Containment of Biohazards, Viral Load, MESH: Virus Inactivation, 3. Good health, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, chemical inactivation, Positive-strand RNA Viruses, Cambodia, MESH: Viral Load, Viral load, Research Article, MESH: Cells, Cultured, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), 030106 microbiology, Biology, MESH: Hot Temperature, Virus, Specimen Handling, MESH: Containment of Biohazards, 03 medical and health sciences, Virology, Animals, Humans, MESH: SARS-CoV-2, MESH: Specimen Handling, Live virus, MESH: Humans, Animal, SARS-CoV-2, 030306 microbiology, business.industry, MESH: Cambodia, biosafety, COVID-19, 030104 developmental biology, Virus Inactivation, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abadf2f5e3c0d04747da302c1101e064
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المؤلفون: Guy Serre, Marie Reynier, Alain Moga, Corinne Leprince, Sophie Allart, Dominique Goudounèche, Michel Simon
المساهمون: Unité différenciation épidermique et auto-immunité rhumatoïde (UDEAR), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de Physiopathologie Toulouse Purpan (CPTP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de Microscopie Électronique Appliquée à la Biologie (CMEAB), Hôpital de Rangueil, CHU Toulouse [Toulouse]-CHU Toulouse [Toulouse]-Toulouse Réseau Imagerie-Genotoul ( TRI-Genotoul), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), SYNELVIA, Toulouse Réseau Imagerie-Genotoul ( TRI-Genotoul), CCSD, Accord Elsevier
المصدر: Journal of Investigative Dermatology
Journal of Investigative Dermatology, Nature Publishing Group, 2019, 139 (7), pp.1430-1438. ⟨10.1016/j.jid.2018.12.021⟩
Journal of Investigative Dermatology, 2019, 139 (7), pp.1430-1438. ⟨10.1016/j.jid.2018.12.021⟩مصطلحات موضوعية: Keratinocytes, 0301 basic medicine, Lamellar granule, Biochemistry, Cell junction, 0302 clinical medicine, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Claudin-1, Myosin, MESH: Tight Junctions / metabolism, RNA, Small Interfering, MESH: Myosin Heavy Chains / genetics, Cytoskeleton, Cells, Cultured, MESH: Keratinocytes / metabolism, integumentary system, Chemistry, MESH: Epidermis / pathology, Cell biology, Actin Cytoskeleton, Protein Transport, MESH: Intercellular Signaling Peptides and Proteins / metabolism, medicine.anatomical_structure, 030220 oncology & carcinogenesis, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, symbols, Intercellular Signaling Peptides and Proteins, MESH: Myosin Heavy Chains / metabolism, Protein Binding, MESH: Cells, Cultured, MESH: Actin Cytoskeleton / metabolism, MESH: Protein Transport, Myosin Type V, Dermatology, MESH: Myosin Type V / genetics, Tight Junctions, MESH: Actins / metabolism, 03 medical and health sciences, symbols.namesake, MESH: Keratinocytes / pathology, medicine, Stratum corneum, Humans, MESH: Protein Binding, MESH: Claudin-1 / metabolism, Molecular Biology, Actin, MESH: Humans, Myosin Heavy Chains, MESH: rab GTP-Binding Proteins / metabolism, MESH: RNA, Small Interfering / genetics, MESH: Myosin Type V / metabolism, Cell Biology, Golgi apparatus, Actins, MESH: Epidermis / metabolism, 030104 developmental biology, rab GTP-Binding Proteins, Epidermis
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b23279e57f8e5cb9731c489548ae9e
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المؤلفون: Patrice Decker, Mireille Sebbag, Julie Mussard, Marie-Christophe Boissier, Matthieu Ribon, Luca Semerano, Sarra Seninet, Cyril Clavel, Guy Serre
المساهمون: Physiopathologie, cibles et thérapies de la polyarthrite rhumatoïde (Li2P), Institut National de la Santé et de la Recherche Médicale (INSERM)-UFR Santé, Médecine et Biologie Humaine-Université Sorbonne Paris Cité (USPC)-Université Paris 13 (UP13), Unité différenciation épidermique et auto-immunité rhumatoïde (UDEAR), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), CCSD, Accord Elsevier, Université Paris 13 (UP13)-Université Sorbonne Paris Cité (USPC)-UFR Santé, Médecine et Biologie Humaine-Institut National de la Santé et de la Recherche Médicale (INSERM)
المصدر: Journal of Autoimmunity
Journal of Autoimmunity, Elsevier, 2019, 98, pp.122-131. ⟨10.1016/j.jaut.2019.01.003⟩
Journal of Autoimmunity, 2019, 98, pp.122-131. ⟨10.1016/j.jaut.2019.01.003⟩مصطلحات موضوعية: Male, 0301 basic medicine, Lipopolysaccharide, Neutrophils, Autoimmunity, Neutrophil extracellular traps, Extracellular Traps, Anti-Citrullinated Protein Antibodies, Arthritis, Rheumatoid, chemistry.chemical_compound, MESH: Aged, 80 and over, 0302 clinical medicine, MESH: Arthritis, Rheumatoid / immunology, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Immunology and Allergy, Cells, Cultured, MESH: Aged, Aged, 80 and over, MESH: Middle Aged, biology, Chemistry, MESH: Anti-Citrullinated Protein, MESH: Neutrophils / immunology, Interleukin, Middle Aged, MESH: Antibodies / metabolism, 3. Good health, Pathogenic mechanisms, Integrin alpha M, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Female, medicine.symptom, Cell activation, MESH: Cells, Cultured, Adult, MESH: Antimicrobial Cationic Peptides / metabolism, Immunology, MESH: Immunomodulation, Inflammation, Immune complex formation, Proinflammatory cytokine, Immunomodulation, 03 medical and health sciences, Cathelicidins, MESH: Autoimmunity, medicine, Humans, MESH: Extracellular Traps / metabolism, Aged, MESH: Inflammation / immunology, 030203 arthritis & rheumatology, MESH: Humans, MESH: Complement C1q / metabolism, Complement C1q, Rheumatoid arthritis, MESH: Adult, MESH: Complement C1q / immunology, MESH: Male, 030104 developmental biology, biology.protein, MESH: Antimicrobial Cationic Peptides / immunology, MESH: Female, Antimicrobial Cationic Peptides
وصف الملف: application/pdf
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المؤلفون: Fogel, Olivier, Bugge Tinggaard, Andreas, Fagny, Maud, Sigrist, Nelly, Roche, Elodie, Leclere, Laurence, Deleuze, Jean-François, Batteux, Frederic, Dougados, Maxime, Miceli-Richard, Corinne, Tost, Jörg
المساهمون: Institut de Biologie François JACOB (JACOB), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Service de rhumatologie [CHU Cochin], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Descartes - Paris 5 (UPD5), Aarhus University [Aarhus], Hôpital Cochin [AP-HP], Immunorégulation - Immunoregulation, Institut Pasteur [Paris] (IP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Cité (UPCité), The research described in this manuscript was mainly funded by a Sirius research award (UCB Pharma S.A.). Additional funding was obtained through a Passerelle research award (Pfizer), iCARE (MSD Avenir) and the institutional budget of the CNRGH. O.F. is the recipient of a PhD fellowship from Assistance Publique - Hopitaux de Paris / CEA (poste accueil AP-HP)., Fagny, Maud
المصدر: Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-14 (2019)
Fogel, O, Bugge Tinggaard, A, Fagny, M, Sigrist, N, Roche, E, Leclere, L, Deleuze, J F, Batteux, F, Dougados, M, Miceli-Richard, C & Tost, J 2019, ' Deregulation of microRNA expression in monocytes and CD4 + T lymphocytes from patients with axial spondyloarthritis ', Arthritis Research and Therapy, vol. 21, no. 1, 51 . https://doi.org/10.1186/s13075-019-1829-7
Arthritis Research & Therapy
Arthritis Research & Therapy, 2019, 21 (1), pp.1-14. ⟨10.1186/s13075-019-1829-7⟩مصطلحات موضوعية: MESH: Antirheumatic Agents, lcsh:Diseases of the musculoskeletal system, MESH: Spondylarthritis, [SDV]Life Sciences [q-bio], MESH: Monocytes, Monocytes, MESH: Gene Expression Profiling, MESH: Reverse Transcriptase Polymerase Chain Reaction, Spondyloarthritis, MESH: Cohort Studies, [SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], MESH: Humans, MESH: Middle Aged, CD4 T lymphocytes, MESH: CD4-Positive T-Lymphocytes, MESH: Adult, CD4+ T lymphocytes, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], MESH: Male, [SDV] Life Sciences [q-bio], [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, Epigenetics, lcsh:RC925-935, MiRNA, MESH: Spine, MESH: Female, MESH: MicroRNAs, MESH: Cells, Cultured
وصف الملف: Electronic; application/pdf
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المؤلفون: David A. Patten, Céline Aguer, Marc Foretz, Léa Garneau, Lucien Nadeau, Le Bris S. Quinn, E.E. Pistilli, Michael W. McBurney, Barbara G. Anderson, P. Haddad, Audrey Caron, Mary-Ellen Harper, E. Pinault-Masson, Karen Jardine
المساهمون: Unité de Catalyse et Chimie du Solide - Equipes du Site Artois (UCCS Artois), Unité de Catalyse et Chimie du Solide - UMR 8181 (UCCS), Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Lille (ENSCL)-Ecole Centrale de Lille-Université d'Artois (UA)-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Lille (ENSCL)-Ecole Centrale de Lille-Université d'Artois (UA), Laboratoire Hubert Curien [Saint Etienne] (LHC), Institut d'Optique Graduate School (IOGS)-Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS), National Center for Atmospheric Research [Boulder] (NCAR)
المصدر: Biochimica et Biophysica Acta (BBA)-General Subjects
Biochimica et Biophysica Acta (BBA)-General Subjects, Elsevier, 2019, 1863 (2), pp.395-407. ⟨10.1016/j.bbagen.2018.10.021⟩مصطلحات موضوعية: MESH: Oxidation-Reduction, 0301 basic medicine, Glucose uptake, MESH: Interleukin-15, Respiratory chain, AMP-Activated Protein Kinases, Mitochondrion, Biochemistry, MESH: Dose-Response Relationship, Drug, Mice, 0302 clinical medicine, MESH: Animals, Mitochondrial supercomplexes, MESH: AMP-Activated Protein Kinases, Cells, Cultured, Interleukin-15, MESH: Muscle, Skeletal, Chemistry, Myogenesis, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Insulin sensitivity, Mitochondria, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM], MESH: Glucose, medicine.anatomical_structure, Oxidation-Reduction, MESH: Cells, Cultured, medicine.medical_specialty, MESH: Rats, MESH: Mitochondria, MESH: Mice, Transgenic, Cell Respiration, Biophysics, Mice, Transgenic, 030209 endocrinology & metabolism, Oxidative phosphorylation, Article, Electron Transport, 03 medical and health sciences, Myokine, Internal medicine, medicine, Animals, Muscle, Skeletal, MESH: Electron Transport, MESH: Mice, Molecular Biology, Dose-Response Relationship, Drug, AMPK, Skeletal muscle, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Rats, Glucose, 030104 developmental biology, Endocrinology, Myotubes, MESH: Cell Respiration
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المؤلفون: Simon Cauchemez, Elisabeth Carniel, Christian E. Demeure, Christiane Gerke, Chloé Guillas, Anne Derbise, Javier Pizarro-Cerdá
المساهمون: Yersinia, Institut Pasteur [Paris], Modélisation mathématique des maladies infectieuses, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Centre de Bioinformatique, Biostatistique et Biologie Intégrative (C3BI), The project was supported by an ANR Emergence grant (ANR-12-EMMA-0011-01) and an Institut Pasteur Accelerating Preclinical Candidates – GPF – Vaccinology 2015 grant (GPFVacc2-08)., ANR-12-EMMA-0011,PLAGVAC,Développement pré-clinique d'un vaccin vivant contre la peste(2012), Institut Pasteur [Paris] (IP), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Vaccine
Vaccine, Elsevier, 2019, 37 (1), pp.123-129. ⟨10.1016/j.vaccine.2018.11.022⟩
Vaccine, 2019, 37 (1), pp.123-129. ⟨10.1016/j.vaccine.2018.11.022⟩مصطلحات موضوعية: Yersinia pestis, 0302 clinical medicine, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Yersinia pseudotuberculosis, MESH: Animals, LcrV, 030212 general & internal medicine, Immunity, Cellular, Mice, Inbred BALB C, MESH: Cytokines, biology, Antibodies, Bacterial, 3. Good health, Vaccination, Infectious Diseases, [SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunology, MESH: Yersinia pseudotuberculosis, Molecular Medicine, Plague vaccine, Female, MESH: Cells, Cultured, Pneumonic plague, IgG, 030231 tropical medicine, MESH: Yersinia pestis, Live vaccine, Vaccines, Attenuated, MESH: Mice, Inbred Strains, MESH: Plague, Interferon-gamma, 03 medical and health sciences, Immune system, Bacterial Proteins, Antigen, Correlates of protection, MESH: Vaccines, Attenuated, medicine, Animals, MESH: Mice, Antigens, Bacterial, Plague Vaccine, Plague, General Veterinary, General Immunology and Microbiology, Public Health, Environmental and Occupational Health, biology.organism_classification, medicine.disease, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, Immunity, Humoral, Mice, Inbred C57BL, F1, Immunoglobulin G, Immunology, [SDV.IMM.VAC]Life Sciences [q-bio]/Immunology/Vaccinology, MESH: Female
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المؤلفون: Carys A. Croft, James P. Di Santo, Antonia Cama, Solenne Marie, Carmen Buchrieser, Davide Topazio, Olimpia Musumeci, Valerie Dardalhon, Laura Surace, Naomi Taylor, Jean-Marc Doisne, Vincent Guillemot, Natalia Petrosemoli, Pedro Escoll, Ido Amit, Anna Thaller
المساهمون: Immunité Innée - Innate Immunity, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), École Doctorale Bio Sorbonne Paris Cité [Paris] (ED562 - BioSPC), Université Sorbonne Paris Cité (USPC)-Université Paris Cité (UPCité), Biologie des Bactéries intracellulaires - Biology of Intracellular Bacteria, Université Paris Cité (UPCité)-Microbiologie Intégrative et Moléculaire (UMR6047), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité), Institut de Génétique Moléculaire de Montpellier (IGMM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Department of Otolaryngology, Ospedale 'Giuseppe Mazzini' di Teramo, Department of Maxillofacial and Otolaryngology, Hospital 'Floraspe Renzetti', Department of Immunology [Rehovot, Israël], Weizmann Institute of Science [Rehovot, Israël], Department of Clinical and Experimental Medicine [Messina, Italy], University of Messina, The Innate Immunity Unit is supported by grants from the Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur, the Agence National pour le Recherche (ANR) and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (695467, ILC_REACTIVITY). A.T. is supported by European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement no. 765104. C.B.’s group was supported by the Fondation pour la Recherche Médicale (FRM) grant no. EQU201903007847 and the grant no. ANR-10-LABX-62-IBEID. L.S. was supported by an SNSF-Early PostDoc. Mobility fellowship and a Marie Curie grant (H2020- MSCA-IF-2017)., We thank all the members of the Innate Immunity Unit for helpful discussions, the Centre de Recherche Translationnelle and the logistic department of Institut Pasteur. We thank the CB-UTechS platform for cytometry support and the Imagopole-CiTech (part of France-BioImaging supported by ANR grant no. ANR-10-INSB-04-01, Conseil de la Region Ile-de-France, FRM) for technical support., The study was conceptualized by L.S. and J.P.D. Experiments were coordinated by L.S. FACS and subsequent analyses were performed by L.S., C.A.C., A.T., J.-M.D. and S.M. Confocal microscopy analysis was performed by P.E., C.B. and L.S. Bioinformatic analyses were performed by N.P. and V.G. RNA-seq experiments were conducted by I.A. O.M., V.D., N.T., D.T. and A.C. provided resources. L.S. and J.P.D. wrote the paper. Funding was acquired by L.S. and J.P.D., and the study was supervised by J.P.D., ANR-10-INBS-0004,France-BioImaging,Développment d'une infrastructure française distribuée coordonnée(2010), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), European Project: 695467,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) ,ILC_REACTIVITY(2016), European Project: 765104,MATURE-NK, European Project: 796004,BIF-SCV, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), École Doctorale Bio Sorbonne Paris Cité [Paris] (ED BioSPC), Université Sorbonne Paris Cité (USPC)-Université de Paris (UP), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Hospital 'Giuseppe Mazzini'
المصدر: Nature Immunology
Nature Immunology, 2021, 22 (11), pp.1367-1374. ⟨10.1038/s41590-021-01043-8⟩
Nature Immunology, Nature Publishing Group, 2021, 22 (11), pp.1367-1374. ⟨10.1038/s41590-021-01043-8⟩مصطلحات موضوعية: Letter, Mitochondrial Diseases, Lymphocyte Activation, 0302 clinical medicine, Immunology and Allergy, Glycolysis, Receptor, Tissue homeostasis, Cells, Cultured, 0303 health sciences, MESH: Cytokines, Innate lymphoid cell, MESH: Energy Metabolism, MESH: Arginine, MESH: Mitochondrial Diseases, MESH: Case-Control Studies, Cell biology, Mitochondria, Phenotype, [SDV.IMM]Life Sciences [q-bio]/Immunology, Cytokines, MESH: Immunity, Innate, MESH: Cells, Cultured, MESH: Interleukin-33, MESH: Mitochondria, Immunology, Innate lymphoid cells, Oxidative phosphorylation, Biology, MESH: Phenotype, Arginine, 03 medical and health sciences, Th2 Cells, MESH: Th2 Cells, MESH: Cell Proliferation, Humans, MESH: Lymphocyte Activation, PI3K/AKT/mTOR pathway, 030304 developmental biology, Cell Proliferation, MESH: Humans, Interleukins, Metabolism, Interleukin-33, Immunity, Innate, Metabolic pathway, Case-Control Studies, Energy Metabolism, Amino Acids, Branched-Chain, 030215 immunology, MESH: Amino Acids, Branched-Chain