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1Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes
المؤلفون: Xavier Brazzolotto, Florian Nachon, Marko Živin, Jure Stojan, Maja Zorović, Damijan Knez, Jacques-Philippe Colletier, Urban Košak, Stanislav Gobec, Stane Pajk, Nicolas Coquelle
المساهمون: Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA), Institut Laue-Langevin (ILL), Institut de Recherche Biomédicale des Armées [Antenne Marseille] (IRBA), Institut de biologie structurale (IBS - UMR 5075), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), Institut de Recherche Biomédicale des Armées (IRBA), ILL, University of Ljubljana, Faculty of Pharmacy, Askerceva 7, 1000 Ljubljana, Slovenia, Faculty of Pharmacy, University of Ljubljana, Département de Toxicologie et Risques Chimiques, Institute of Biochemistry, Faculty of Medicine
المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020, 35 (1), pp.498-505. ⟨10.1080/14756366.2019.1710502⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, Informa Healthcare, 2020, 35 (1), pp.498-505. ⟨10.1080/14756366.2019.1710502⟩
Journal of enzyme inhibition and medicinal chemistry, vol. 35, no. 1, pp. 498-505, 2020.
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 498-505 (2020)مصطلحات موضوعية: Models, Molecular, [SDV]Life Sciences [q-bio], Crystallography, X-Ray, 01 natural sciences, Mice, chemistry.chemical_compound, Drug Discovery, MESH: Animals, Butyrylcholinesterase, chemistry.chemical_classification, zaviralci, Molecular Structure, biology, MESH: Butyrylcholinesterase, General Medicine, MESH: Fluorescent Dyes, Fluorescence, Acetylcholinesterase, MESH: Amides, 3. Good health, inhibitor, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM], Fluorescence intensity, Biochemistry, butyrylcholinesterase, fluorescence, patogeneza Alzheimerjeve bolezni, MESH: Cholinesterase Inhibitors, MESH: Models, Molecular, Research Paper, MESH: Molecular Structure, Mixed inhibition, RM1-950, probe, butiriliholinesteraza, Hydrolase, Animals, Humans, [CHIM]Chemical Sciences, udc:616.894+616.892.3:615.2, MESH: Mice, Fluorescent Dyes, Pharmacology, MESH: Humans, 010405 organic chemistry, Active site, MESH: Crystallography, X-Ray, Amides, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Enzyme, chemistry, biology.protein, Therapeutics. Pharmacology, Cholinesterase Inhibitors
وصف الملف: application/pdf; text/url
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المؤلفون: Janko Kos, Anja Pišlar, Xavier Brazzolotto, Marko Jukič, Stanislav Gobec, Jacques-Philippe Colletier, Nicolas Coquelle, Simon Žakelj, Florian Nachon, Janez Mravljak, Damijan Knez, Matej Sova
المساهمون: Faculty of Pharmacy, University of Ljubljana, Institut de biologie structurale (IBS - UMR 5075 ), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Toxicology, Centre de Recherches du Service de Santé des Armées, Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA), Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherche Biomédicale des Armées (IRBA)
المصدر: European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, 2018, 156, pp.598-617. ⟨10.1016/j.ejmech.2018.07.033⟩
European Journal of Medicinal Chemistry, Elsevier, 2018, 156, pp.598-617. ⟨10.1016/j.ejmech.2018.07.033⟩مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Antioxidant, DPPH, Multi-target-directed ligands, medicine.medical_treatment, MESH: Drug Design, Ligands, Antioxidants, chemistry.chemical_compound, 0302 clinical medicine, 8-hydroxyquinoline, Piperidines, Drug Discovery, MESH: Ligands, Butyrylcholinesterase, chemistry.chemical_classification, MESH: Butyrylcholinesterase, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], General Medicine, MESH: Neuroprotective Agents, Alzheimer's disease, MESH: Amyloid beta-Peptides, 3. Good health, MESH: Piperidines, Neuroprotective Agents, Biochemistry, Efflux, MESH: Caco-2 Cells, MESH: Cholinesterase Inhibitors, Intracellular, MESH: Models, Molecular, MESH: Cell Line, Tumor, Neuroprotection, 03 medical and health sciences, Alzheimer Disease, Cell Line, Tumor, medicine, Humans, Chelation, Pharmacology, Reactive oxygen species, MESH: Humans, Amyloid beta-Peptides, Organic Chemistry, MESH: Antioxidants, 030104 developmental biology, chemistry, Drug Design, Cholinesterase Inhibitors, Caco-2 Cells, 030217 neurology & neurosurgery, MESH: Alzheimer Disease
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المؤلفون: Monika C. Žužek, Robert Frangež, Marjana Grandič, Evelyne Benoit
المساهمون: University of Ljubljana, Service d'Ingénierie Moléculaire pour la Santé (ex SIMOPRO) (SIMoS), Médicaments et Technologies pour la Santé (MTS), Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut des Neurosciences Paris-Saclay (NeuroPSI), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Toxicology Letters
Toxicology Letters, Elsevier, 2017, 281, pp.95-101. ⟨10.1016/j.toxlet.2017.09.007⟩
Toxicology Letters, 2017, 281, pp.95-101. ⟨10.1016/j.toxlet.2017.09.007⟩مصطلحات موضوعية: 0301 basic medicine, Male, MESH: Phrenic Nerve, Polymers, MESH: Muscle Contraction, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Neuromuscular transmission, Pyridinium Compounds, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, Receptors, Nicotinic, AChE inhibitors, Toxicology, Synaptic Transmission, Membrane Potentials, Mice, MESH: Animals, MESH: Inhibitory Concentration 50, MESH: Muscle, Skeletal, Mice, Inbred BALB C, biology, General Medicine, MESH: Polymers, Phrenic Nerve, medicine.anatomical_structure, [SDV.TOX]Life Sciences [q-bio]/Toxicology, MESH: Pyridinium Compounds, MESH: Receptors, Nicotinic, Tetanic contraction, medicine.symptom, MESH: Cholinesterase Inhibitors, Muscle contraction, Muscle Contraction, medicine.medical_specialty, Diaphragm, MESH: Mice, Inbred BALB C, Neuromuscular Junction, Skeletal muscle contraction, Neuromuscular junction, Contractility, 03 medical and health sciences, Inhibitory Concentration 50, Internal medicine, MESH: Synaptic Transmission, medicine, MESH: Membrane Potentials, Animals, Muscle, Skeletal, MESH: Mice, Cholinesterase, Acetylcholine receptor, Motor endplate potential, Skeletal muscle, Motor endplate 38 potential, MESH: Male, Disease Models, Animal, 030104 developmental biology, Endocrinology, MESH: Diaphragm, Natural Poly-APS, biology.protein, Biophysics, MESH: Neuromuscular Junction, Cholinesterase Inhibitors, MESH: Disease Models, Animal
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المؤلفون: Thomas Freret, Véronique Lelong-Boulouard, Pierre Lecouflet, François Dauphin, Katia Hamidouche, Michel Boulouard
المساهمون: Groupe Mémoire et Plasticité comportementale (GMPc), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU), Mobilités : Vieillissement, Pathologie, Santé (COMETE), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Caen Normandie (UNICAEN), Université de Caen Normandie - UFR Santé (UNICAEN Santé)
المصدر: Psychopharmacology
Psychopharmacology, Springer Verlag, 2017, 234 (15), pp.2365-2374. ⟨10.1007/s00213-017-4664-z⟩مصطلحات موضوعية: Male, 0301 basic medicine, MESH: Serotonin 5-HT4 Receptor Agonists, Nicotinic Antagonists, Receptors, Nicotinic, Pharmacology, Neurodegenerative, MESH: Allosteric Regulation, Mice, 0302 clinical medicine, Piperidines, MESH: Animals, Aniline Compounds, [SDV.BA]Life Sciences [q-bio]/Animal biology, Spontaneous alternation, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, MESH: Memory Disorders, 3. Good health, Nicotinic agonist, MESH: Piperidines, Acetylcholinesterase inhibitor, MESH: Receptors, Nicotinic, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], MESH: Cholinesterase Inhibitors, medicine.drug, Agonist, Serotonin, Allosteric modulator, medicine.drug_class, Scopolamine, MESH: Receptors, Serotonin, 5-HT4, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Partial agonist, MESH: Scopolamine, MESH: Aniline Compounds, Serotonin 5-HT4 Receptor Agonists, 03 medical and health sciences, Allosteric Regulation, Alzheimer Disease, Memory, medicine, Galantamine, Animals, MESH: Mice, MESH: Galantamine, Memory Disorders, Behavior, business.industry, MESH: Nicotinic Antagonists, Symptomatic relief, MESH: Male, 030104 developmental biology, Cholinesterase Inhibitors, Receptors, Serotonin, 5-HT4, business, Neuroscience, 030217 neurology & neurosurgery, MESH: Alzheimer Disease
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المؤلفون: Florian Nachon, Marie Trovaslet, Xavier Brazzolotto, Patrick Masson
المساهمون: Institut de biologie structurale (IBS - UMR 5075 ), Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Métalloprotéine (MEP), Université Joseph Fourier - Grenoble 1 (UJF)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)
المصدر: Chemico-Biological Interactions
Chemico-Biological Interactions, Elsevier, 2013, 206 (3), pp.536-544. ⟨10.1016/j.cbi.2013.06.012⟩
Chemico-Biological Interactions, 2013, 206 (3), pp.536-544. ⟨10.1016/j.cbi.2013.06.012⟩مصطلحات موضوعية: Dipeptidases, CBDP, CHO, MESH: Chemical Warfare Agents, Antidotes, human paraoxonase, polyethyleneglycol, TOCP, organophosphorus nerve agent, Toxicology, chemistry.chemical_compound, 0302 clinical medicine, phosphotriesterase, Drug Discovery, PRAD, Chemical Warfare Agents, Butyrylcholinesterase, Nerve agent, chemistry.chemical_classification, 0303 health sciences, proline rich attachment domain, MESH: Butyrylcholinesterase, MESH: Dipeptidases, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], biology, MESH: Antidotes, Chemistry, OPNA, acetylcholinesterase, General Medicine, Directed evolution, Acetylcholinesterase, hPON-1, Biochemistry, high density lipoprotein, Bioscavenger, butyrylcholinesterase, TMPP, PTE, MESH: Cholinesterase Inhibitors, Pretreatment, medicine.drug, HDL, cholinesterase, MESH: Aryldialkylphosphatase, Organophosphate poisoning, triorthocresylphosphate, 03 medical and health sciences, Enzyme Reactivators, ChE, MESH: Drug Discovery, BChE, MESH: Enzyme Reactivators, medicine, Humans, 2-(o-cresyl)-4H-1, 030304 developmental biology, Cholinesterase, MESH: Genetic Therapy, 2-benzodioxaphosphoran-2-one or cresyl saligenin phosphate, MESH: Humans, Medical countermeasures, Aryldialkylphosphatase, MESH: Organophosphate Poisoning, Genetic Therapy, carboxylesterase, medicine.disease, PEG, Chinese hamster ovary, trimethylolpropane phosphate or ethyl bicylclophosphate, Treatment, Enzyme, PEGylation, biology.protein, AChE, Cholinesterase Inhibitors, CaE, 030217 neurology & neurosurgery
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المؤلفون: Hideo Akaoka, Jian-Sheng Lin, Yi-Ping Hou, Yan Zhao, Minnamaija Lintunen, Pertti Panula, Régis Parmentier, Takeshi Watanabe, Magali Perier, Patricia Franco
المساهمون: Centre de recherche en neurosciences de Lyon (CRNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Medicum, Pertti Panula / Principal Investigator, Neuroscience Center, Department of Anatomy
المصدر: Neuropharmacology
Neuropharmacology, Elsevier, 2016, 106, pp.20-34. ⟨10.1016/j.neuropharm.2015.12.014⟩مصطلحات موضوعية: 0301 basic medicine, Male, MESH: Triprolidine, SLEEP-WAKING CYCLE, Physostigmine, [SDV]Life Sciences [q-bio], Cortical activation, POSTERIOR HYPOTHALAMUS, MESH: Mice, Knockout, Cholinergic Antagonists, chemistry.chemical_compound, Histamine receptor, [SCCO]Cognitive science, 0302 clinical medicine, ANTAGONISTS, Ciproxifan, MESH: Animals, MESH: Cholinergic Antagonists, EEG, H1-receptor, NEURONS, ta317, Mice, Knockout, Triprolidine, Imidazoles, Brain, Histidine decarboxylase, RECEPTORS, Histamine H1 Antagonists, MESH: Histamine H1 Antagonists, Arousal, MESH: Cholinesterase Inhibitors, Compensation, MESH: Histamine H3 Antagonists, Histamine, MESH: Imidazoles, medicine.drug, Histamine H3 Antagonists, medicine.medical_specialty, MESH: Sleep, MESH: Receptors, Histamine H3, Scopolamine, Histamine H1 receptor, MESH: Receptors, Histamine H1, Cholinergic transmission, MESH: Scopolamine, 03 medical and health sciences, Cellular and Molecular Neuroscience, MESH: Brain, PARADOXICAL SLEEP, MESH: Mice, Inbred C57BL, CEREBRAL-CORTEX, Internal medicine, medicine, Inverse agonist, Animals, Receptors, Histamine H3, Receptors, Histamine H1, Wakefulness, Pharmacology, Behavior, OUT MICE, 3112 Neurosciences, Histaminergic, MESH: Physostigmine, ta3124, NERVOUS-SYSTEM, MESH: Male, Mice, Inbred C57BL, MESH: Wakefulness, 030104 developmental biology, Endocrinology, chemistry, Cholinergic, 3111 Biomedicine, Cholinesterase Inhibitors, Sleep, 030217 neurology & neurosurgery, Knockout mice
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المؤلفون: Charles Ramassamy, Lé Dao, Sihem Doggui, Jasjeet K Sahni, Javed Ali, Sanjula Baboota
المساهمون: Institut Armand Frappier (INRS-IAF), Institut National de la Recherche Scientifique [Québec] (INRS)-Réseau International des Instituts Pasteur (RIIP), Department of Pharmaceutics, Faculty of Pharmacy-Jamia Hamdard, Faculté de Médecine, Université Laval [Québec] (ULaval), The financial support from NSERC (LD) and FQRNT (LD, CR) is gratefully acknowledged.
المصدر: Journal of Controlled Release
Journal of Controlled Release, Elsevier, 2011, 152 (2), pp.208-31. ⟨10.1016/j.jconrel.2010.11.033⟩مصطلحات موضوعية: Pathology, Pharmaceutical Science, Disease, MESH: Chelating Agents, Bioinformatics, MESH: Blood-Brain Barrier, Drug Delivery Systems, MESH: Phenols, MESH: Hormones, Degenerative disease, MESH: Animals, Chelating Agents, media_common, education.field_of_study, MESH: Vasoactive Intestinal Peptide, Blood-Brain Barrier, [SDV.TOX]Life Sciences [q-bio]/Toxicology, Drug delivery, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Alzheimer's disease, MESH: Cholinesterase Inhibitors, Vasoactive Intestinal Peptide, Drug, Amyloid, medicine.medical_specialty, media_common.quotation_subject, MESH: Drug Delivery Systems, Population, Phenols, Alzheimer Disease, medicine, Animals, Humans, education, Flavonoids, MESH: Amyloid, MESH: Humans, business.industry, Polyphenols, medicine.disease, Hormones, Targeted drug delivery, Nanoparticles, Cholinesterase Inhibitors, Nanocarriers, business, MESH: Flavonoids, MESH: Alzheimer Disease, MESH: Nanoparticles, MESH: Polyphenols
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المؤلفون: Zoran Radić, Yves Bourne, Palmer Taylor, Pascale Marchot
المساهمون: Architecture et fonction des macromolécules biologiques (AFMB), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-Institut National de la Recherche Agronomique (INRA), Department of pharmacology, University of California [San Diego] (UC San Diego), University of California-University of California, Centre de recherche en neurobiologie - neurophysiologie de Marseille (CRN2M), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), University of California (UC)-University of California (UC)
المصدر: Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2010, 132 (51), pp.18292-300. ⟨10.1021/ja106820e⟩
Journal of the American Chemical Society, 2010, 132 (51), pp.18292-300. ⟨10.1021/ja106820e⟩مصطلحات موضوعية: Protein Conformation, MESH: Catalytic Domain, Crystallography, X-Ray, 01 natural sciences, Biochemistry, MESH: Tyrosine, Active center, chemistry.chemical_compound, MESH: Protein Conformation, Colloid and Surface Chemistry, Protein structure, Non-competitive inhibition, Catalytic Domain, MESH: Crystallization, 0303 health sciences, MESH: Kinetics, MESH: Phenanthridines, Acetylcholinesterase, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM], Phenanthridines, MESH: HEK293 Cells, Tacrine, Crystallization, MESH: Cholinesterase Inhibitors, medicine.drug, MESH: Mutation, Stereochemistry, Triazole, MESH: Binding, Competitive, 010402 general chemistry, Binding, Competitive, Article, Catalysis, 03 medical and health sciences, Hydrolase, medicine, Humans, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], 030304 developmental biology, MESH: Humans, General Chemistry, MESH: Acetylcholinesterase, MESH: Crystallography, X-Ray, 0104 chemical sciences, Kinetics, HEK293 Cells, chemistry, Mutation, Tyrosine, Cholinesterase Inhibitors, Azide, MESH: Tacrine
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المساهمون: Pharmacologie des Immunosuppresseurs et de la Transplantation (PIST), Université de Limoges (UNILIM)-CHU Limoges-Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST FR CNRS 3503)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Pharmacologie, toxicologie et pharmacovigilance [CHU Limoges], CHU Limoges, Université de Limoges (UNILIM), Institut universitaire de formation des maîtres - Limousin (IUFM Limousin), Institut de Mathématiques de Toulouse UMR5219 (IMT), Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Chimie des Substances Naturelles (LCSN), Université de Limoges (UNILIM)-Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST FR CNRS 3503), Groupement de Recherche Eau, Sol, Environnement (GRESE), Service de Médecine Gériatrique [CHU Limoges], Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)
المصدر: Analytical Biochemistry
Analytical Biochemistry, 2009, 389 (2), pp.97-101. ⟨10.1016/j.ab.2009.03.041⟩
Analytical Biochemistry, Elsevier Masson, 2009, 389 (2), pp.97-101. ⟨10.1016/j.ab.2009.03.041⟩مصطلحات موضوعية: MESH: Microchemistry, Tris, Isothermal microcalorimetry, Stereochemistry, MESH: Molecular Structure, MESH: Paraoxon, Kinetics, Biophysics, Calorimetry, Biochemistry, Paraoxon, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Reaction rate constant, medicine, Organophosphorus compound, Animals, MESH: Animals, Horses, Butyrylcholine, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], MESH: Calorimetry, MESH: Horses, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Molecular Structure, MESH: Butyrylcholinesterase, MESH: Kinetics, Microchemistry, Substrate (chemistry), Cell Biology, chemistry, Butyrylcholinesterase, 030220 oncology & carcinogenesis, Physical chemistry, Cholinesterase Inhibitors, MESH: Cholinesterase Inhibitors, medicine.drug
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المؤلفون: Judith Peters, Florian Nachon, Patrick Masson, Marcus Trapp, Moeava Tehei, M M Koza, Martin Weik, Marie Trovaslet, N Martinez
المساهمون: Thomas, Frank, Institute of human genetics, Medical University Graz, Biocomplexité des écosystèmes coralliens de l'Indo-Pacifique (CoReUS2), Institut de biologie structurale (IBS - UMR 5075 ), Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Institut Laue-Langevin (ILL), ILL, Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)
المصدر: Journal of the Royal Society Interface
Journal of the Royal Society Interface, the Royal Society, 2014, 11 (97), pp.20140372
Journal of the Royal Society Interface, 2014, 11 (97), pp.20140372مصطلحات موضوعية: MESH: Enzyme Activation, [SDV.BBM.BS] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Statistics as Topic, Biomedical Engineering, Biophysics, Thermal fluctuations, Bioengineering, Neutron scattering, Molecular Dynamics Simulation, Biochemistry, Inelastic neutron scattering, Catalysis, Biomaterials, Molecular dynamics, Alkaloids, MESH: Alkaloids, Humans, MESH: Protein Binding, MESH: Molecular Dynamics Simulation, Research Articles, MESH: Statistics as Topic, Binding Sites, MESH: Humans, MESH: Kinetics, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Chemistry, Relaxation (NMR), MESH: Models, Chemical, Nanosecond, MESH: Acetylcholinesterase, MESH: Catalysis, Enzyme Activation, Crystallography, Kinetics, Models, Chemical, MESH: Binding Sites, Chemical physics, Picosecond, Density of states, Acetylcholinesterase, MESH: Sesquiterpenes, Cholinesterase Inhibitors, MESH: Cholinesterase Inhibitors, Sesquiterpenes, Biotechnology, Protein Binding
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