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المؤلفون: Fran Robson, Palma Rocchi, Sinem Demirbag, Thi Khanh Le, Khadija Shahed Khan, Clément Paris, Peter Barfuss, Wai-Lung Ng
المساهمون: University of Bristol [Bristol], The Chinese University of Hong Kong [Hong Kong], Centre de Recherche en Cancérologie de Marseille (CRCM), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Aix Marseille Université (AMU), Hanoi University of Science and Technology (HUST), Sabanci University, Nanotechnology Research and Application Center, Sabanci University [Istanbul], Université Paris-Est (UPE), Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Rocchi, Palma
المصدر: Molecular Cell
Molecular Cell, Elsevier, 2020, 79 (5), pp.710-727. ⟨10.1016/j.molcel.2020.07.027⟩
Molecular Cell, 2020, 79 (5), pp.710-727. ⟨10.1016/j.molcel.2020.07.027⟩مصطلحات موضوعية: antisense oligonucleotide, Transcription, Genetic, MESH: Coronavirus Infections, viruses, [SDV]Life Sciences [q-bio], Cell, coronavirus, Cytidine, Viral Nonstructural Proteins, medicine.disease_cause, Virus Replication, Genome, Severity of Illness Index, 0302 clinical medicine, Transcription (biology), MESH: Molecular Targeted Therapy, MESH: COVID-19, Nucleotide, MESH: Adenosine Monophosphate, Molecular Targeted Therapy, Coronavirus, chemistry.chemical_classification, 0303 health sciences, Alanine, non-structural protein 14, virus diseases, ExoN, MESH: Amides, 3. Good health, [SDV] Life Sciences [q-bio], medicine.anatomical_structure, 030220 oncology & carcinogenesis, MESH: Pyrazines, MESH: RNA, Viral, Pyrazines, Proofreading, MESH: Betacoronavirus, RNA, Viral, MESH: Genome, Viral, Coronavirus Infections, MESH: Cytidine, medicine.drug, MESH: Antiviral Agents, MESH: Pandemics, MESH: Mutation, exonuclease, MESH: Alanine, CoV, Pneumonia, Viral, antisense oligonucleotide (ASO), Computational biology, Genome, Viral, Biology, Therapeutic targeting, Hydroxylamines, Antiviral Agents, Article, ASO, 03 medical and health sciences, Betacoronavirus, MESH: Severity of Illness Index, Coronavirus (CoV), medicine, Humans, MESH: SARS-CoV-2, anti-coronavirus drugs, Molecular Biology, Pandemics, 030304 developmental biology, Exonuclease (ExoN), MESH: Ribonucleosides, MESH: Humans, Nucleoside analogue, SARS-CoV-2, MESH: Transcription, Genetic, MESH: Virus Replication, nucleoside analog, RNA, COVID-19, Correction, MESH: Hydroxylamines, Cell Biology, Amides, Adenosine Monophosphate, non-structural protein 14 (nsp14), respiratory tract diseases, nucleoside analogue (NA), Viral replication, chemistry, MESH: Pneumonia, Viral, Mutation, nsp14, MESH: Viral Nonstructural Proteins, NA, Ribonucleosides, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e7c3d34b3a0e2ab6d0db7eece5c7f1
https://pubmed.ncbi.nlm.nih.gov/33338403 -
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المساهمون: Medical oncology laboratory, AGEM - Re-generation and cancer of the digestive system, CCA - Imaging and biomarkers, Division of Pharmacology and Chemotherapy, Department of Internal Medicine, University of Pisa - Università di Pisa, Simulation and Modeling of Adaptive Response for Therapeutics in Cancer (SMARTc), Centre de Recherche en Cancérologie de Marseille (CRCM), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Aix Marseille Université (AMU), Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
المصدر: British Journal of Clinical Pharmacology, 85(6), 1213-1214. Wiley-Blackwell
British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology, Wiley, 2019, 85 (6), pp.1213-1214. ⟨10.1111/bcp.13921⟩
Br J Clin Pharmacol
British Journal of Clinical Pharmacology, 2019, 85 (6), pp.1213-1214. ⟨10.1111/bcp.13921⟩
Peters, G J, Giovannetti, E, Honeywell, R J & Ciccolini, J 2019, ' Can cytidine deaminase be used as predictive biomarker for gemcitabine toxicity and response? ', British Journal of Clinical Pharmacology, vol. 85, no. 6, pp. 1213-1214 . https://doi.org/10.1111/bcp.13921مصطلحات موضوعية: therapeutic drug monitoring, [SDV]Life Sciences [q-bio], [SDV.BC]Life Sciences [q-bio]/Cellular Biology, 030226 pharmacology & pharmacy, Deoxycytidine, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, medicine, Humans, Pharmacology (medical), MESH: Neoplasms, ComputingMilieux_MISCELLANEOUS, Predictive biomarker, cytidine deaminase, MESH: Cytidine Deaminase, Pharmacology, MESH: Humans, medicine.diagnostic_test, business.industry, MESH: Deoxycytidine, gemcitabine, Cytidine deaminase, Original Articles, Gemcitabine, 3. Good health, Therapeutic drug monitoring, 030220 oncology & carcinogenesis, Toxicity, Cancer research, MESH: Biomarkers, business, Biomarkers, medicine.drug
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المؤلفون: Caval, Mohamed S. Bouzidi, Jean-Pierre Vartanian, Michel Henry, Rodolphe Suspène, Simon Wain-Hobson
المساهمون: Rétrovirologie Moléculaire, Institut Pasteur [Paris] (IP), This work was supported by grants from the Institut Pasteur, INCa and the CNRS. VC and MSB were supported by OSEO and the Ligue Nationale Contre le Cancer.
المصدر: British Journal of Cancer
British Journal of Cancer, 2014, 110 (10), pp.2615-2622. ⟨10.1038/bjc.2014.176⟩مصطلحات موضوعية: MESH: Neoplasm Proteins, CD4-Positive T-Lymphocytes, Cancer Research, [SDV]Life Sciences [q-bio], MESH: beta Catenin, Cytidine, medicine.disease_cause, Nucleic Acid Denaturation, Genome, Polymerase Chain Reaction, law.invention, Cytosine Deaminase, chemistry.chemical_compound, MESH: Liver Neoplasms, law, APOBEC Deaminases, APOBEC3A, MESH: Carcinoma, Hepatocellular, Polymerase chain reaction, Cells, Cultured, beta Catenin, Genetics, Recombination, Genetic, Mutation, Liver Neoplasms, MESH: APOBEC Deaminases, Temperature, MESH: CD4-Positive T-Lymphocytes, APOBEC3, DNA, Neoplasm, MESH: Temperature, MESH: Hepatitis C, Chronic, Nuclear DNA, Neoplasm Proteins, Oncology, MESH: Recombination, Genetic, MESH: Interferon-alpha, MESH: Cytidine, MESH: Cells, Cultured, MESH: Mutation, Carcinoma, Hepatocellular, MESH: Hepatitis B, Chronic, MESH: DNA, Neoplasm, Context (language use), Genomics, MESH: Nucleic Acid Denaturation, Biology, MESH: Phytohemagglutinins, Hepatitis B, Chronic, Cytidine Deaminase, medicine, Humans, 3DPCR, Phytohemagglutinins, MESH: Cytidine Deaminase, cancer genomics, MESH: Humans, MESH: Cytosine Deaminase, hypermutation, Interferon-alpha, MESH: Interleukin-2, MESH: Polymerase Chain Reaction, Genetics and Genomics, Hepatitis C, Chronic, chemistry, Interleukin-2, DNA
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المساهمون: Rétrovirologie Moléculaire, Institut Pasteur [Paris] (IP), This work was supported by grants from the Institut Pasteur and Oséo (grant number FUI AAP 12). V.C. was supported by a postdoctoral grant from OSEO.
المصدر: Molecular Biology and Evolution
Molecular Biology and Evolution, 2014, 31 (2), pp.330-340. ⟨10.1093/molbev/mst195⟩مصطلحات موضوعية: Models, Molecular, Genome instability, [SDV]Life Sciences [q-bio], MESH: DNA Breaks, Double-Stranded, MESH: Protein Structure, Secondary, MESH: Amino Acid Sequence, Cytidine, Protein Structure, Secondary, Madin Darby Canine Kidney Cells, MESH: Dogs, chemistry.chemical_compound, Gene cluster, MESH: Animals, MESH: Proteins, DNA Breaks, Double-Stranded, APOBEC3A, MESH: Phylogeny, Phylogeny, Mammals, Genetics, double-strand breaks, MESH: Genomic Instability, MESH: DNA, APOBEC3, Cytidine deaminase, Nuclear DNA, Deamination, MESH: HEK293 Cells, MESH: Cytidine, MESH: Models, Molecular, MESH: Mutation, Molecular Sequence Data, MESH: Sequence Alignment, Biology, MESH: Mammals, Genomic Instability, Dogs, Cytidine Deaminase, Animals, Humans, Amino Acid Sequence, Molecular Biology, Ecology, Evolution, Behavior and Systematics, MESH: Cytidine Deaminase, MESH: Deamination, MESH: Humans, MESH: Molecular Sequence Data, hypermutation, nuclear DNA, MESH: Madin Darby Canine Kidney Cells, Proteins, DNA, methylcytidine, genomic DNA, HEK293 Cells, chemistry, MESH: HeLa Cells, Mutation, Sequence Alignment, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47840f223a21ab569487e3e51ecd161
https://doi.org/10.1093/molbev/mst195 -
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المؤلفون: Vincent Caval, J Thalmensi, T Bestetti, E Pliquet, L Fiette, M Julithe, T. Huet, Anna Kostrzak, M Escande, Simon Wain-Hobson, Pierre Langlade-Demoyen
المساهمون: Invectys [Paris], Rétrovirologie moléculaire, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Histopathologie humaine et Modèles animaux, Institut Pasteur [Paris], Université Sorbonne Paris Cité (USPC), Département Infection et Epidémiologie - Department of Infection and Epidemiology, This work was supported by Invectys., Rétrovirologie moléculaire - Molecular Retrovirology, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP)
المصدر: Gene Therapy
Gene Therapy, Nature Publishing Group, 2017, 24 (2), pp.74-83. ⟨10.1038/gt.2016.77⟩
Gene Therapy, 2017, 24 (2), pp.74-83. ⟨10.1038/gt.2016.77⟩مصطلحات موضوعية: 0301 basic medicine, Male, [SDV.BIO]Life Sciences [q-bio]/Biotechnology, Cancer therapy, Hydrolases, Genetic enhancement, [SDV]Life Sciences [q-bio], MESH: Electroporation/methods, Melanoma, Experimental, Mice, 0302 clinical medicine, Tumor Cells, Cultured, MESH: Animals, Fibrosarcoma, Melanoma, MESH: Lymphocytes, Tumor-Infiltrating/immunology, MESH: Cytidine Deaminase/genetics, Electroporation, MESH: Melanoma, Experimental/therapy, Cytidine deaminase, Cytological techniques, 030220 oncology & carcinogenesis, Molecular Medicine, Female, Plasmids, Somatic hypermutation, Vectors in gene therapy, Gene delivery, Biology, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, MESH: Melanoma, Experimental/genetics, MESH: Mice, Inbred C57BL, Cytidine Deaminase, Genetics, medicine, MESH: Genetic Therapy, Animals, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, MESH: Tumor Cells, Cultured, Molecular Biology, MESH: Mice, Proteins, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Genetic Therapy, medicine.disease, Molecular biology, MESH: Male, Mice, Inbred C57BL, 030104 developmental biology, MESH: Proteins/genetics, Genetic engineering, MESH: Melanoma, Experimental/immunology, MESH: Plasmids/genetics, MESH: Female
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المؤلفون: Denise Guetard, Marc Sitbon, Jean-Pierre Vartanian, Anne Keriel, Myrtille Renard, Simon Wain-Hobson, Vincent Petit
المساهمون: Rétrovirologie Moléculaire, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Moléculaire de Montpellier (IGMM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique ( CNRS ), Institut de Génétique Moléculaire de Montpellier ( IGMM ), Université de Montpellier ( UM ) -Centre National de la Recherche Scientifique ( CNRS )
المصدر: Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2009, 385 (1), pp.65-78. ⟨10.1016/j.jmb.2008.10.043⟩
Journal of Molecular Biology, 2009, 385 (1), pp.65-78. ⟨10.1016/j.jmb.2008.10.043⟩
Journal of Molecular Biology, Elsevier, 2009, 385 (1), pp.65-78. 〈10.1016/j.jmb.2008.10.043〉مصطلحات موضوعية: Hypoxanthine Phosphoribosyltransferase, MESH : Molecular Sequence Data, MESH : RNA, Messenger, MESH : DNA, Complementary, MESH : NIH 3T3 Cells, viruses, Muscle Proteins, MESH: Base Sequence, Nucleic Acid Denaturation, MESH : Retroviridae Infections, MESH: Animals, Newborn, Mice, chemistry.chemical_compound, MESH : Hypoxanthine Phosphoribosyltransferase, Structural Biology, Murine leukemia virus, MESH : RNA, MESH: Animals, APOBEC Deaminases, MESH : Cytidine Deaminase, Gammaretrovirus, MESH : Muscle Proteins, 0303 health sciences, biology, Nucleotides, MESH : Animals, Newborn, 030302 biochemistry & molecular biology, MESH: Leukemia Virus, Murine, Cytidine, Cytidine deaminase, MESH: Apolipoproteins B, 3. Good health, Leukemia Virus, Murine, MESH: Retroviridae Infections, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, MESH : Mutation, MESH: Genome, Viral, MESH : Genome, Viral, MESH : Leukemia Virus, Murine, MESH : Nucleic Acid Denaturation, APOBEC, DNA, Complementary, MESH: Mutation, APOBEC-1 Deaminase, Molecular Sequence Data, MESH: Leukemia, Experimental, Genome, Viral, MESH: Nucleic Acid Denaturation, [ SDV.MP.VIR ] Life Sciences [q-bio]/Microbiology and Parasitology/Virology, MESH: Muscle Proteins, 03 medical and health sciences, MESH: RNA, Cytidine Deaminase, MESH : Mice, MESH : RNA Editing, Animals, Humans, MESH: RNA Editing, RNA, Messenger, MESH: Mice, Molecular Biology, Apolipoproteins B, MESH: RNA, Messenger, MESH: Cytidine Deaminase, 030304 developmental biology, Messenger RNA, Leukemia, Experimental, MESH: Molecular Sequence Data, MESH: Humans, Base Sequence, APOBEC1, MESH : Humans, MESH: Tumor Virus Infections, RNA, MESH : Apolipoproteins B, MESH: DNA, Complementary, biology.organism_classification, MESH: Hypoxanthine Phosphoribosyltransferase, Molecular biology, MESH: Nucleotides, Tumor Virus Infections, Animals, Newborn, chemistry, Mutation, NIH 3T3 Cells, MESH : Nucleotides, MESH : Leukemia, Experimental, MESH : Base Sequence, MESH : Animals, RNA Editing, MESH : Tumor Virus Infections, Retroviridae Infections, MESH: NIH 3T3 Cells
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المؤلفون: Benoit Arcangioli, Hanen Ouadani, Beya Larguèche, Imen Ben-Mustapha, Hatem Masmoudi, François Rougeon, Houda Elloumi-Zghal, Mohamed-Ridha Barbouche, Tihana Jovanic, Meriem Ben-Ali, Mongia Hachicha, Dahmani M. Fathallah, Sylvie Garcia
المساهمون: Laboratoire de Transmission, Contrôle et Immunobiologie des Infections - Laboratory of Transmission, Control and Immunobiology of Infection (LR11IPT02), Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Université de Tunis El Manar (UTM), Génétique et Biochimie du Développement, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Biologie des Populations Lymphocytaires, Dynamique du Génome - Dynamics of the genome, Hedi Chaker Hospital [Sfax], This work was supported by the Ministry of Health (Tunisia)., Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS)
المصدر: Molecular Immunology
Molecular Immunology, 2016, 79, pp.77-82. ⟨10.1016/j.molimm.2016.09.025⟩
Molecular Immunology, Elsevier, 2016, 79, pp.77-82. ⟨10.1016/j.molimm.2016.09.025⟩مصطلحات موضوعية: 0301 basic medicine, MESH: Somatic Hypermutation, Immunoglobulin, MESH: Mutation, [SDV]Life Sciences [q-bio], Immunology, Mutant, Nonsense mutation, Blotting, Western, Reversion, Somatic hypermutation, chemical and pharmacologic phenomena, medicine.disease_cause, Hyper-IgM Immunodeficiency Syndrome, 03 medical and health sciences, Jurkat Cells, Cytidine Deaminase, Activation-induced (cytidine) deaminase, medicine, MESH: Jurkat Cells, Humans, MESH: Blotting, Western, AID mutagenic activity, Molecular Biology, MESH: Cytidine Deaminase, Mutation, MESH: Humans, biology, Cofactors, Activation induced cytidine deaminase, Molecular biology, Immunoglobulin Class Switching, 3. Good health, Class switch recombination, MESH: Mutagenesis, Site-Directed, 030104 developmental biology, Immunoglobulin class switching, MESH: Hyper-IgM Immunodeficiency Syndrome, MESH: Immunoglobulin Class Switching, biology.protein, Mutagenesis, Site-Directed, Hyper IgM 2, Somatic Hypermutation, Immunoglobulin, DNA deamination
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المؤلفون: Samuel Aparicio, Jessica Zucman-Rossi, Julia Richter, Stefan M. Pfister, Matthias Schlesner, Nikhil C. Munshi, Sean M. Grimmond, Andrew V. Biankin, Christine Desmedt, Rafael Valdés-Mas, Ton N. Schumacher, Elias Campo, Marina Pajic, Peter J. Campbell, Lucy R. Yates, David T. W. Jones, Laura van ’t Veer, Michael R. Stratton, Carlos Caldas, Matthew Meyerson, Hiromi Nakamura, Sandrine Boyault, Anne Vincent-Salomon, Keiran Raine, Peter Lichter, Marit M. van Buuren, Tomislav Ilicic, Stian Knappskog, Ultan McDermott, Sancha Martin, Andrew Tutt, Icgc PedBrain, Helen Davies, Barbara Hutter, Philip Rosenstiel, Sunil R. Lakhani, Marcin Imielinsk, John A. Foekens, Fumie Hosoda, Sandrine Imbeaud, Elli Papaemmanuil, David T. Jones, Nicola Waddell, Serena Nik-Zainal, Marcel Kool, Graham R. Bignell, Yasushi Totoki, Manasa Ramakrishna, Paul A. Northcott, Niccolo Bolli, Xose S. Puente, Adam Butler, Åke Borg, David C. Wedge, Jon W. Teague, Andrea L. Richardson, Reiner Siebert, Tatsuhiro Shibata, John V. Pearson, Carlos López-Otín, Angelo Paradiso, P. Andrew Futreal, Anne Lise Børresen-Dale, Sam Behjati, Birgit Burkhardt, Paul N. Span, Jorunn E. Eyfjord, Mel Greaves, Roland Eils, Ludmil B. Alexandrov, Natalie Jäger
المساهمون: Other departments, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, CCA -Cancer Center Amsterdam, Oncology, Medical Oncology, Pulmonary Medicine, Centre de Recherche en Automatique de Nancy (CRAN), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Centre Alexis Vautrin (CAV), Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL)
المصدر: Nature, 500(7463), 415-421. Nature Publishing Group
Nature, 500, 7463, pp. 415-21
Nature, 500(7463), 415-+. Nature Publishing Group
Nature
Nature, Nature Publishing Group, 2013, 500 (7463), pp.415-421. ⟨10.1038/nature12477⟩
Nature, 500, 415-21مصطلحات موضوعية: Male, 0302 clinical medicine, Neoplasms, APOBEC Deaminases, DNA Mutational Analysis, MESH: Neoplasms, MESH: Aging, MESH: Models, Genetic, MESH: DNA Mutational Analysis, Exome, MESH: Organ Specificity, MESH: Mutagenesis, Genetics, 0303 health sciences, Multidisciplinary, MESH: DNA, MESH: Sequence Deletion, 3. Good health, MESH: Reproducibility of Results, Cell Transformation, Neoplastic, 030220 oncology & carcinogenesis, Female, DNA mismatch repair, APOBEC, MESH: Mutation, Somatic hypermutation, MESH: Algorithms, Biology, Article, Quality of Care [ONCOL 4], 03 medical and health sciences, SDG 3 - Good Health and Well-being, Translational research [ONCOL 3], Cytidine Deaminase, MESH: Mutagens, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Humans, ddc:610, MESH: Cytidine Deaminase, 030304 developmental biology, MESH: Humans, MESH: Transcription, Genetic, MESH: Mutagenesis, Insertional, Mutagenesis, MESH: Cell Transformation, Neoplastic, Evaluation of complex medical interventions [NCEBP 2], Kataegis, Mutation, Hormonal regulation Aetiology, screening and detection [IGMD 6], Human genome
وصف الملف: application/pdf
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المؤلفون: Alexis Saintamand, Yves Denizot, Michel Cogné, Christelle Vincent-Fabert, Bernardo Reina-San-Martin, Pauline Rouaud, Isabelle Robert, Rémi Fiancette, Eric Pinaud, Marie Marquet
المساهمون: Contrôle de la Réponse Immune B et des Lymphoproliférations (CRIBL), Centre National de la Recherche Scientifique (CNRS)-Université de Limoges (UNILIM)-Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST FR CNRS 3503), Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
المصدر: The Journal of Experimental Medicine
Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2013, 210 (8), pp.1501-7. ⟨10.1084/jem.20130072⟩مصطلحات موضوعية: MESH: VDJ Exons, Transcription, Genetic, Immunoglobulin Variable Region, MESH: Immunoglobulin Variable Region, Gene Expression, Regulatory Sequences, Nucleic Acid, MESH: Mice, Knockout, Mice, 0302 clinical medicine, MESH: Germinal Center, Immunology and Allergy, MESH: Animals, 3' Untranslated Regions, MESH: Chromatin Immunoprecipitation, Mice, Knockout, B-Lymphocytes, 0303 health sciences, MESH: 3' Untranslated Regions, Cytidine deaminase, MESH: Gene Expression Regulation, [SDV.IMM]Life Sciences [q-bio]/Immunology, Immunoglobulin Heavy Chains, MESH: Immunoglobulin Heavy Chains, MESH: Somatic Hypermutation, Immunoglobulin, Chromatin Immunoprecipitation, MESH: Gene Expression, Immunology, MESH: Immunoglobulin kappa-Chains, Somatic hypermutation, Biology, Immunoglobulin light chain, Immunoglobulin kappa-Chains, 03 medical and health sciences, MESH: B-Lymphocytes, Cytidine Deaminase, MESH: Regulatory Sequences, Nucleic Acid, Animals, Enhancer, MESH: Mice, Central element, MESH: Cytidine Deaminase, 030304 developmental biology, MESH: Transcription, Genetic, Brief Definitive Report, Germinal center, Germinal Center, Molecular biology, Gene Expression Regulation, Immunoglobulin class switching, Immunoglobulin heavy chain, VDJ Exons, Somatic Hypermutation, Immunoglobulin, 030215 immunology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f80c73517706ccf8515835fcf135780f
https://doi.org/10.1084/jem.20130072 -
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المؤلفون: Pierre Briozzo, Thomas Bertrand, Augustin Ofiteru, Béatrice Golinelli-Pimpaneau, Nadia Bucurenci, Anne-Marie Gilles, Octavian Bârzu, Liliane Assairi, Hélène Munier-Lehmann
المساهمون: Laboratoire d'enzymologie et biochimie structurales (LEBS), Centre National de la Recherche Scientifique (CNRS), Chimie Biologique (UCB), Institut National de la Recherche Agronomique (INRA)-Institut National Agronomique Paris-Grignon (INA P-G), Chimie Structurale des Macromolécules (CSM), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Laboratory of Enzymology and Applied Microbiology, Institut Cantacuzène, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2002, 315 (5), pp.1099-110. ⟨10.1006/jmbi.2001.5286⟩
Journal of Molecular Biology, 2002, 315 (5), pp.1099-110. ⟨10.1006/jmbi.2001.5286⟩مصطلحات موضوعية: Models, Molecular, Protein Conformation, [SDV]Life Sciences [q-bio], MESH: Arabinonucleotides, MESH: Amino Acid Sequence, MESH: Drug Design, Crystallography, X-Ray, Cytidine Diphosphate, Substrate Specificity, chemistry.chemical_compound, MESH: Protein Conformation, MESH: Structure-Activity Relationship, Models, Structural Biology, [SDV.IDA]Life Sciences [q-bio]/Food engineering, Serine, Nucleotide, Phosphorylation, chemistry.chemical_classification, 0303 health sciences, Crystallography, Nucleoside-phosphate kinase, MESH: Kinetics, MESH: Escherichia coli, 030302 biochemistry & molecular biology, MESH: Arginine, MESH: Cytidine Diphosphate, Deoxyribose, Biochemistry, MESH: Deoxycytosine Nucleotides, MESH: Pentoses, MESH: Models, Molecular, Protein Binding, Cytidine monophosphate, MESH: Mutation, MESH: Deoxycytidine Monophosphate, Molecular Sequence Data, Pentoses, MESH: Sequence Alignment, Arginine, Catalysis, Structure-Activity Relationship, 03 medical and health sciences, Ribose, Cytidine Monophosphate, Escherichia coli, [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, MESH: Protein Binding, MESH: Cytidine Monophosphate, [SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering, Amino Acid Sequence, MESH: Serine, Molecular Biology, 030304 developmental biology, Binding Sites, MESH: Molecular Sequence Data, Arabinonucleotides, MESH: Phosphorylation, Molecular, DCMP phosphorylation, Deoxycytidine Monophosphate, MESH: Catalysis, MESH: Crystallography, X-Ray, CMP phosphorylation, carbohydrates (lipids), Kinetics, MESH: Binding Sites, chemistry, Drug Design, Deoxycytosine Nucleotides, Mutation, X-Ray, MESH: Substrate Specificity, Nucleoside-Phosphate Kinase, Sequence Alignment, MESH: Nucleoside-Phosphate Kinase, Nucleoside, Dideoxynucleotides
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