المؤلفون: Le Ribeuz, Hélène, Dumont, Florent, Ruellou, Guillaume, Lambert, Mélanie, Balliau, Thierry, Quatredeniers, Marceau, Girerd, Barbara, Cohen-Kaminsky, Sylvia, Mercier, Olaf, Yen-Nicolaÿ, Stéphanie, Humbert, Marc, Montani, David, Capuano, Véronique, Antigny, Fabrice

المساهمون: Faculté de Médecine Paris-Saclay, AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre)-Université Paris-Saclay, Hypertension pulmonaire : physiopathologie et innovation thérapeutique (HPPIT), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Ingénierie et Plateformes au Service de l'Innovation Thérapeutique (IPSIT), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Génétique Quantitative et Evolution - Le Moulon (Génétique Végétale) (GQE-Le Moulon), AgroParisTech-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut National de la Santé et de la Recherche Médicale (INSERM), INSERM, Université Paris-Saclay, Marie Lannelongue Hospital, Therapeutic Innovation Doctoral School (ED569), Région Ile de France (convention n◦ EX024607), ANR-18-CE14-0023,KAPAH,KCNK3 une nouvelle cible thérapeutique dans l'hypertension artérielle pulmonaire(2018), Adhésion et Inflammation (LAI), Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre Chirurgical Marie Lannelongue (CCML), Hôpital Bicêtre, Plateforme d'Analyse Protéomique de Paris Sud Ouest (PAPPSO), AgroParisTech, Antigny, Fabrice

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21 (19), pp.1-21. ⟨10.3390/ijms21197400⟩
International Journal of Molecular Sciences, Vol 21, Iss 7400, p 7400 (2020)
International Journal of Molecular Sciences, 2020, 21 (19), pp.7400. ⟨10.3390/ijms21197400⟩
Volume 21
Issue 19

مصطلحات موضوعية: Proteomics, MESH: Signal Transduction, Proteome, [SDV]Life Sciences [q-bio], Myocytes, Smooth Muscle, MESH: Pulmonary Artery, Nerve Tissue Proteins, MESH: Molecular Sequence Annotation, Pulmonary Artery, Article, lcsh:Chemistry, Potassium Channels, Tandem Pore Domain, Humans, MESH: Endothelial Cells, MESH: Nerve Tissue Proteins, lcsh:QH301-705.5, Cells, Cultured, proteomic, MESH: Humans, MESH: Proteomics, Computational Biology, Endothelial Cells, MESH: Potassium Channels, Tandem Pore Domain, Molecular Sequence Annotation, MESH: Myocytes, Smooth Muscle, PAH, MESH: Gene Knockdown Techniques, MESH: Gene Expression Regulation, [SDV] Life Sciences [q-bio], MESH: Proteome, Gene Expression Regulation, lcsh:Biology (General), lcsh:QD1-999, Gene Knockdown Techniques, MESH: Biomarkers, Biomarkers, Signal Transduction, MESH: Cells, Cultured, MESH: Computational Biology, potassium channel

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e6378b5b5ce2157dfda3ba916cc7f522
https://hal.archives-ouvertes.fr/hal-03096431/document

المؤلفون: Margaret Buckingham, Sigolène M. Meilhac

المساهمون: Coordination des Cellules et Morphogenèse / Heart Morphogenesis (Imagine - Institut Pasteur U1163), Institut Pasteur [Paris] (IP)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Département de Biologie du Développement et Cellules souches - Department of Developmental and Stem Cell Biology, Institut Pasteur [Paris] (IP), Biologie du Développement et Cellules souches (CNRS UMR3738), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Work in the group of S.M.M. is supported by the Institut Imagine, the Institut Pasteur, INSERM and the Université Paris Descartes. M.E.B. acknowledges support from the Institut Pasteur and the Centre National de la Recherche Scientifique (CNRS, UMR 3738).

المصدر: Nature Reviews Cardiology
Nature Reviews Cardiology, 2018, 15 (11), pp.705-724. ⟨10.1038/s41569-018-0086-9⟩

مصطلحات موضوعية: 0301 basic medicine, MESH: Signal Transduction, Heart malformation, Organogenesis, Gene regulatory network, MESH: Myocytes, Cardiac, Regenerative Medicine, Regenerative medicine, Transcriptome, MESH: Gene Expression Regulation, Developmental, Medicine, MESH: Animals, MESH: Endothelial Cells, Gene Regulatory Networks, Myocytes, Cardiac, MESH: Gene Regulatory Networks, MESH: Regeneration, Gene Expression Regulation, Developmental, MESH: Myocytes, Smooth Muscle, Cell Differentiation, Phenotype, Cardiology and Cardiovascular Medicine, Signal Transduction, MESH: Cell Differentiation, Heart Defects, Congenital, Cell type, Lineage (genetic), Myocytes, Smooth Muscle, Cell fate determination, MESH: Phenotype, 03 medical and health sciences, Fetal Heart, MESH: Cell Proliferation, Animals, Humans, Regeneration, Cell Lineage, Progenitor cell, Cell Proliferation, MESH: Humans, business.industry, Endothelial Cells, [SDV.BDD.MOR]Life Sciences [q-bio]/Development Biology/Morphogenesis, MESH: Heart Defects, Congenital, MESH: Cell Lineage, Fibroblasts, MESH: Organogenesis, 030104 developmental biology, MESH: Fetal Heart, Evolutionary biology, MESH: Fibroblasts, MESH: Regenerative Medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5201a5bac3eef64fc0870d95afc2a71e
https://pubmed.ncbi.nlm.nih.gov/30266935

المؤلفون: Marc Foretz, Sandy MacMillan, Benoit Viollet, Javier Moral-Sanz, D. Grahame Hardie, Carmel M. Moran, Sophronia A. Lewis, A. Mark Evans, Fiona A. Ross, Adrian Thomson

المساهمون: Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), College of Life Sciences, University of Dundee

المصدر: Science Signaling
Science Signaling, American Association for the Advancement of Science, 2018, 11 (550), pp.eaau0296. ⟨10.1126/scisignal.aau0296⟩
Moral-Sanz, J, Lewis, S A, MacMillan, S, Ross, F A, Thomson, A, Viollet, B, Foretz, M, Moran, C, Hardie, D G & Evans, A M 2018, ' The LKB1-AMPK-α1 signalling pathway triggers hypoxic pulmonary vasoconstriction downstream of mitochondria ', Science Signaling, vol. 11, no. 550 . https://doi.org/10.1126/scisignal.aau0296

مصطلحات موضوعية: 0301 basic medicine, MESH: Signal Transduction, AMP-Activated Protein Kinases, Mitochondrion, Biochemistry, MESH: Mice, Knockout, MESH: Hypoxia, Hypoxic pulmonary vasoconstriction, Myocyte, MESH: Animals, MESH: AMP-Activated Protein Kinases, Hypoxia, CAMKK2, Mice, Knockout, chemistry.chemical_classification, MESH: Reactive Oxygen Species, MESH: Myocytes, Smooth Muscle, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM], Mitochondria, 3. Good health, Cell biology, MESH: HEK293 Cells, MESH: Vasoconstriction, medicine.symptom, Signal transduction, Signal Transduction, MESH: Mice, Transgenic, MESH: Mitochondria, Myocytes, Smooth Muscle, MESH: Pulmonary Artery, Mice, Transgenic, Protein Serine-Threonine Kinases, Pulmonary Artery, MESH: Protein-Serine-Threonine Kinases, 03 medical and health sciences, MESH: Mice, Inbred C57BL, medicine, Animals, Humans, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], Molecular Biology, Reactive oxygen species, MESH: Humans, AMPK, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Cell Biology, Hypoxia (medical), Mice, Inbred C57BL, HEK293 Cells, 030104 developmental biology, chemistry, Vasoconstriction, Reactive Oxygen Species

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c754dea92d6a8f84a902dff8e5998ade
https://hal.archives-ouvertes.fr/hal-02348836

المؤلفون: Joffrey Zoll, Jean-François Decaux, Mathias Mericskay, Marie Breton, Anne Garnier, Boris Manoury, Mélanie Gressette, Cynthia Tannous, Jérôme Piquereau, Charles Brenner, Nicolas Diguet, István Baczkó, Samuel A.J. Trammell, Jocelyne Blanc, Zhenlin Li, Anne Gouge, Nathalie Mougenot, Gareth G. Lavery, Robin Deloux

المساهمون: Adaptation Biologique et Vieillissement = Biological Adaptation and Ageing (B2A), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Signalisation et physiopathologie cardiovasculaire (UMRS1180), Institut National de la Santé et de la Recherche Médicale (INSERM), Phénotypage du petit animal (UMS28), Université Pierre et Marie Curie - Paris 6 (UPMC), Détoxication et réparation tissulaire, Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire de Photophysique et Photochimie Supramoléculaires et Macromoléculaires (PPSM), École normale supérieure - Cachan (ENS Cachan)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche Cardiovasculaire de Lariboisiere, Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), This study was supported by the Association Française contre les Myopathies (AFM N 16282), the Agence Nationale de la Recherche (ANR) grant NAD-Heart ANR-17-CE17-0015-01 and ANR-08-GENOPAT-038, Fondation de France grant 00075811 and fundings from Institut National pour la Santé Et la Recherche Médicale (INSERM), Center National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie Paris 6, and University Paris Sud. Drs Diguet and Tannous, and Mr Deloux were supported by a PhD fellowship of French Ministère de la Recherche et de l’Enseignement Supérieur. Dr Diguet was further supported by a 1-year PhD fellowship from AFM. Dr Brenner is supported by the Roy J. Carver Trust. GGL is supported by a Wellcome Trust Senior Fellowship (104612/Z/14/Z)., The authors thank V. Veksler and R. Ventura-Clapier (Inserm UMR-S 1180) for expert advice on respiration assays, Luc Bertrand (UCL, Belgium) for expert advice on AMPK detection, A. Angelini (UMR 8256) for technical help in these assays, A. Grosfeld (UMR 8256) for preliminary setup experiments for Nmrk2 cloning, Florence Lefebvre for adult rat cardiomyocyte isolation., ANR-17-CE17-0015,NAD-HEART,Supplémentation en précurseur du NAD+ pour le traitement de l'insuffisance cardiaque(2017), ANR-08-GENO-0038,REMODEL-SRF,Remodelage des organes creux musculaires et dilatations: établir un lien avec le Facteur de Réponse au Sérum(2008), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM), SIGNALISATION ET PHYSIOPATHOLOGIE CARDIOVASCULAIRE (UMRS1180, LabEx LERMIT), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-IFR140-Institut National de la Santé et de la Recherche Médicale (INSERM), École normale supérieure - Cachan (ENS Cachan)-Centre National de la Recherche Scientifique (CNRS), ANR-17-CE17-0015,NAD-HEART,Supplémentation en précurseur du NAD+ pour le traitement de l’insuffisance cardiaque(2017), DECAUX, Jean-François, Supplémentation en précurseur du NAD+ pour le traitement de l'insuffisance cardiaque - - NAD-HEART2017 - ANR-17-CE17-0015 - AAPG2017 - VALID, Du gène à la physiopathologie, des maladies rares aux maladies communes - Remodelage des organes creux musculaires et dilatations: établir un lien avec le Facteur de Réponse au Sérum - - REMODEL-SRF2008 - ANR-08-GENO-0038 - GENOPAT - VALID

المصدر: Circulation
Circulation, 2018, 137 (21), pp.2256-2273. ⟨10.1161/CIRCULATIONAHA.116.026099⟩
Circulation, American Heart Association, 2018, 137 (21), pp.2256-2273. ⟨10.1161/CIRCULATIONAHA.116.026099⟩

مصطلحات موضوعية: 0301 basic medicine, MESH: Niacinamide/analogs & derivatives, Serum Response Factor, MESH: Cytokines/genetics, Cardiomyopathy, MESH: Dietary Supplements, Pyridinium Compounds, Pharmacology, MESH: Acrylamides/therapeutic use, MESH: Myocytes, Cardiac/cytology, AMP-Activated Protein Kinases, [SDV.BBM.BM] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, nicotinamide-beta-riboside, MESH: Cardiomyopathy, Dilated/drug therapy, chemistry.chemical_compound, Mice, Piperidines, energy metabolism, Glycolysis, MESH: Animals, MESH: PPAR alpha/metabolism, Myocytes, Cardiac, MESH: Piperidines/therapeutic use, Nicotinamide Phosphoribosyltransferase, Dilated cardiomyopathy, glycolysis, MESH: Myocytes, Cardiac/metabolism, MESH: Phosphotransferases (Alcohol Group Acceptor)/metabolism, Phosphotransferases (Alcohol Group Acceptor), MESH: Heart Failure/prevention & control, Metabolome, Cytokines, MESH: NAD/metabolism, Cardiology and Cardiovascular Medicine, dilated, acetyl coenzyme A, Cardiac function curve, Cardiomyopathy, Dilated, Niacinamide, MESH: Rats, MESH: Mice, Transgenic, Mice, Transgenic, Oxidative phosphorylation, MESH: Serum Response Factor/genetics, Citric Acid, MESH: Metabolome/drug effects, MESH: Nicotinamide Phosphoribosyltransferase/metabolism, 03 medical and health sciences, MESH: Gene Expression Profiling, MESH: Citric Acid/metabolism, Physiology (medical), medicine, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, MESH: Niacinamide/therapeutic use, Animals, MESH: Serum Response Factor/deficiency, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, PPAR alpha, MESH: Myocytes, Cardiac/drug effects, MESH: Mice, Heart Failure, Acrylamides, business.industry, MESH: Phosphotransferases (Alcohol Group Acceptor)/genetics, Gene Expression Profiling, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, MESH: Nicotinamide Phosphoribosyltransferase/genetics, medicine.disease, NAD, Rats, MESH: AMP-Activated Protein Kinases/metabolism, Disease Models, Animal, 030104 developmental biology, chemistry, Heart failure, Nicotinamide riboside, Dietary Supplements, NAD+ kinase, MESH: Cytokines/metabolism, MESH: Disease Models, Animal, business, cardiomyopathy, MESH: Phosphotransferases (Alcohol Group Acceptor)/antagonists & inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff8c9d79a5527d8a72b3544c248b40d
https://pubmed.ncbi.nlm.nih.gov/29784693

المؤلفون: Emmanuelle Plaisier, Nicolas Mezouar, Ambre Rochey, Anne Joutel, Julien Ratelade, Valérie Domenga-Denier

المساهمون: Génétique et Physiopathologie des Maladies Cérébro-Vasculaires (U1161 / UMR_S 1161), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Des Maladies Rénales Rares aux Maladies Fréquentes, Remodelage et Réparation, Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), CHU Tenon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), DHU NeuroVasc Sorbonne Paris-Cité, Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Dupuis, Christine

المصدر: The Journal of Pathology
The Journal of pathology and bacteriology
The Journal of pathology and bacteriology, John Wiley & Sons, 2018, 244 (4), pp.408-420. ⟨10.1002/path.5023⟩

مصطلحات موضوعية: 0301 basic medicine, MESH: Cerebral Hemorrhage, Pathology, Time Factors, [SDV]Life Sciences [q-bio], Penetrance, Degeneration (medical), MESH: Mice, Knockout, Muscle, Smooth, Vascular, MESH: Blood-Brain Barrier, chemistry.chemical_compound, 0302 clinical medicine, MESH: Penetrance, MESH: Animals, MESH: Endothelial Cells, MESH: Peptide Fragments, Stroke, Mice, Knockout, MESH: Genetic Predisposition to Disease, intracerebral haemorrhage, MESH: Myocytes, Smooth Muscle, MESH: Muscle, Smooth, Vascular, 3. Good health, [SDV] Life Sciences [q-bio], medicine.anatomical_structure, Blood-Brain Barrier, retinal imaging, Disease Progression, MESH: Disease Progression, Collagen Type IV, medicine.medical_specialty, Mice, 129 Strain, Retinal Artery, COL4A1, Myocytes, Smooth Muscle, COL4A2, MESH: Stroke, Pathology and Forensic Medicine, 03 medical and health sciences, MESH: Mice, 129 Strain, MESH: Mice, Inbred C57BL, MESH: Cell Proliferation, Parenchyma, medicine, Animals, Genetic Predisposition to Disease, Pathological, MESH: Collagen Type IV, smooth muscle cell, Cell Proliferation, Cerebral Hemorrhage, Basement membrane, Retina, MESH: Retinal Artery, business.industry, MESH: Time Factors, Endothelial Cells, Retinal, medicine.disease, basement membrane, Peptide Fragments, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, chemistry, MESH: Disease Models, Animal, business, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85ded6d977fa4727e5ff262dc4f880b

المؤلفون: C. Richer, M.-P. Vincent, G. Youcef, François Alhenc-Gelas, Anne Pizard, Elise Belaidi, M. Clemessy, L. Fazal, Ludovic Waeckel, G. Zadigue, Michel Ovize

المساهمون: Centre de Recherche des Cordeliers (CRC), Université Pierre et Marie Curie - Paris 6 (UPMC)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National de la Recherche Agronomique (INRA), Défaillance Cardiovasculaire Aiguë et Chronique (DCAC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Centre d'investigation clinique [Nancy] (CIC), Université Paris Diderot - Paris 7 (UPD7)-École pratique des hautes études (EPHE)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM), CIC-Nancy, Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu [Nancy]-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Pierre et Marie Curie - Paris 6 (UPMC)-École Pratique des Hautes Études (EPHE), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hospices Civils de Lyon (HCL), Université de Lorraine (UL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)

المصدر: Biochemical Pharmacology
Biochemical Pharmacology, Elsevier, 2015, 94 (1), pp.22-29. ⟨10.1016/j.bcp.2015.01.007⟩
Biochemical Pharmacology, 2015, 94 (1), pp.22-29. ⟨10.1016/j.bcp.2015.01.007⟩

مصطلحات موضوعية: Male, MESH: Signal Transduction, Myocardial Ischemia, Gene Expression, MESH: Myocytes, Cardiac, Mitochondrion, Pharmacology, MESH: Voltage-Dependent Anion Channel 1, Mitochondrial Membrane Transport Proteins, MESH: Mice, Knockout, MESH: Cyclosporine, Biochemistry, Mitochondria, Heart, Oxidative Phosphorylation, Cyclophilins, Mice, chemistry.chemical_compound, Cyclosporin a, Myocytes, Cardiac, MESH: Animals, Ischemic Postconditioning, Inner mitochondrial membrane, MESH: Heterozygote, Mice, Knockout, Cardioprotection, Tissue kallikrein, MPTP, Homozygote, MESH: Mitochondrial Membrane Transport Proteins, Mitochondria, Knockout mouse, Cyclosporine, cardiovascular system, Cardiac ischemia–reperfusion, MESH: Myocardial Ischemia, MESH: Mitochondria, Heart, Tissue Kallikreins, Cyclophilin D, Signal Transduction, MESH: Homozygote, Heterozygote, Cardiotonic Agents, MESH: Myocardium, MESH: Gene Expression, MESH: Rats, MESH: Tissue Kallikreins, Ischemia, Biology, MESH: Cyclophilins, MESH: Ischemic Postconditioning, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, MESH: Oxidative Phosphorylation, medicine, Animals, cardiovascular diseases, MESH: Mice, Mitochondrial Permeability Transition Pore, Myocardium, Voltage-Dependent Anion Channel 1, MESH: Cardiotonic Agents, medicine.disease, MESH: Male, Rats, Cyclosporin A, Mitochondrial permeability transition pore, chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db81b18cd655788987a4450d868fcf43
https://doi.org/10.1016/j.bcp.2015.01.007

المؤلفون: Claudio Caccia, Alain Berdeaux, Stéphanie Paradis, Didier Morin, Valerio Leoni

المساهمون: INSERM U955, équipe 3, Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Laboratory of Clinical Pathology and Medical Genetics, Fondazione IRCCS Istituto Neurologico 'Carlo Besta', S. Paradis was supported by a doctoral grant from the Ministère de la Recherche et de la Technologie and by a grant from Trophos. V. Leoni was supported by Italian Mini ster of Health, Fondi per giovani Ricercatori 2008 (GR-2008-1145270). This work was supported by grants of the Fondation de France (grant numbers 2009-002496, 2012- 00029514)., Paradis, S, Leoni, V, Caccia, C, Berdeaux, A, Morin, D

المصدر: Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2013, 98 (3), pp.420-7. ⟨10.1093/cvr/cvt079⟩

مصطلحات موضوعية: Male, Time Factors, Physiology, MESH: Myocytes, Cardiac, Pharmacology, Mitochondrion, Ligands, medicine.disease_cause, Mitochondrial Membrane Transport Proteins, Mitochondria, Heart, Oxidative Phosphorylation, MESH: Benzodiazepinones, MESH: Lipid Peroxidation, MESH: Cholesterol, 0302 clinical medicine, MESH: Membrane Potential, Mitochondrial, MESH: Mitochondrial Membranes, Oximes, MESH: Ligands, MESH: Thiobarbituric Acid Reactive Substances, Myocytes, Cardiac, MESH: Animals, oxysterols, sterols, cholesterol, mass spectrometry, metabolomics, MESH: Receptors, GABA-A, Membrane Potential, Mitochondrial, Cardioprotection, Benzodiazepinones, 0303 health sciences, MESH: Oxidative Stress, biology, MESH: Mitochondrial Membrane Transport Proteins, MESH: Oximes, MESH: Myocardial Reperfusion Injury, Cholesterol, Biochemistry, Mitochondrial matrix, Mitochondrial Membranes, MESH: Mitochondria, Heart, Cardiology and Cardiovascular Medicine, MESH: Rats, Oxysterol, Membrane Fluidity, MESH: Biological Transport, MESH: Protective Agents, MESH: Secosteroids, Myocardial Reperfusion Injury, MESH: Carrier Proteins, Oxidative phosphorylation, Protective Agents, Thiobarbituric Acid Reactive Substances, 03 medical and health sciences, MESH: Oxidative Phosphorylation, Physiology (medical), Translocator protein, medicine, Animals, Secosteroids, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Rats, Wistar, 030304 developmental biology, Mitochondrial Permeability Transition Pore, MESH: Time Factors, Biological Transport, MESH: Rats, Wistar, Receptors, GABA-A, MESH: Male, Rats, Disease Models, Animal, Oxidative Stress, MESH: Cytoprotection, Mitochondrial permeability transition pore, Cytoprotection, biology.protein, Lipid Peroxidation, MESH: Disease Models, Animal, Carrier Proteins, MESH: Membrane Fluidity, 030217 neurology & neurosurgery, Oxidative stress

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2d474a23f56c926f99b5acae10a104
https://doi.org/10.1093/cvr/cvt079

المؤلفون: Alexandre Lucas, Aude Saulière, George S. Baillie, Anne-Coline Laurent, Céline Galés, Magali Berthouze-Duquesnes, Yuan Yan Sin, Frank Lezoualc'h

المساهمون: Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute of Cardiovascular and Medical Sciences [Glasgow], University of Glasgow, Simon, Marie Francoise

المصدر: Cell Signal
Cell Signal, 2013, 25 (4), pp.970-80. ⟨10.1016/j.cellsig.2012.12.007⟩

مصطلحات موضوعية: MESH: Signal Transduction, Scaffold protein, MESH: Fluorescence Resonance Energy Transfer, Arrestins, MESH: Myocytes, Cardiac, 030204 cardiovascular system & hematology, 0302 clinical medicine, MESH: RNA, Small Interfering, Fluorescence Resonance Energy Transfer, Guanine Nucleotide Exchange Factors, MESH: Guanine Nucleotide Exchange Factors, Myocytes, Cardiac, MESH: Animals, Protein Interaction Maps, RNA, Small Interfering, Cells, Cultured, beta-Arrestins, MESH: Protein Interaction Maps, 0303 health sciences, Gene knockdown, Cardiac myocyte, Phosphodiesterase, Cell biology, Biochemistry, MESH: HEK293 Cells, RNA Interference, Rap1, MESH: Arrestins, MESH: Cyclic Nucleotide Phosphodiesterases, Type 3, Signal Transduction, MESH: Cells, Cultured, MESH: Rats, MESH: RNA Interference, Cardiomegaly, Small G Protein, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biology, Proto-Oncogene Proteins p21(ras), MESH: Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Animals, Humans, Nuclear export signal, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, 030304 developmental biology, MESH: Humans, Cell Biology, HDAC4, Cyclic Nucleotide Phosphodiesterases, Type 3, Cyclic Nucleotide Phosphodiesterases, Type 4, Rats, HEK293 Cells, Receptors, Adrenergic, beta-2, MESH: Receptors, Adrenergic, beta-1, Receptors, Adrenergic, beta-1, MESH: Cardiomegaly, MESH: Receptors, Adrenergic, beta-2

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50921a6ab1201fc63978c7e0932db035
https://doi.org/10.1016/j.cellsig.2012.12.007

المؤلفون: Jean-Christophe Olivo-Marin, Chiara V. Ragni, Sigolène M. Meilhac, Jean-François Le Garrec, Margaret Buckingham, Sorin Pop, Alexandre Dufour

المساهمون: Génétique Moléculaire du Développement, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Analyse d'Images Quantitative (AIQ), The work was funded by the Institut Pasteur [PTR335 to S.M.], L’Agence Nationale de la Recherche [11-JSV2-00601 to S.M.], Le Centre National de la Recherche Scientifique and Institut National de la Santé et de la Recherche Médicale. C.V.R. has benefited from a fellowship from the French Ministry of Research. J.F.L.G. was financed with grants from the EU Project ‘CardioCell’ [LT2009-223372 to M.E.B.] and from the Lefoulon-Delalande Foundation., Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2013, 140 (2), pp.395-404. ⟨10.1242/dev.087940⟩
Development; Vol 140
Development (Cambridge, England), 2013, 140 (2), pp.395-404. ⟨10.1242/dev.087940⟩

مصطلحات موضوعية: Surface (mathematics), Time Factors, Cell division, MESH: Myocytes, Cardiac, MESH: Centrosome, Mice, Directional statistics, 0302 clinical medicine, Image Processing, Computer-Assisted, Myocytes, Cardiac, MESH: Animals, [SDV.BDD]Life Sciences [q-bio]/Development Biology, 0303 health sciences, Heart, Anatomy, MESH: Image Processing, Computer-Assisted, Mouse heart morphogenesis, Cell polarity, MESH: Cell Division, Biological system, Cell Division, MESH: Body Patterning, MESH: Cell Nucleus, MESH: Myocardium, Polarity (physics), MESH: Developmental Biology, Morphogenesis, MESH: Imaging, Three-Dimensional, Biology, Clustering, 03 medical and health sciences, Imaging, Three-Dimensional, Animals, Cluster analysis, MESH: Mice, Molecular Biology, Process (anatomy), Body Patterning, 030304 developmental biology, Cell Nucleus, Centrosome, Plane (geometry), Myocardium, MESH: Time Factors, Image segmentation, MESH: Heart, MESH: Anisotropy, Anisotropy, Axial correlation, 030217 neurology & neurosurgery, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c777566624854cd40fcec2d1c11162dc
https://doi.org/10.1242/dev.087940

المؤلفون: Patrick Lacolley, Françoise Poirier, Faiez Zannad, Victoria Cachofeiro, Ernesto Martínez-Martínez, Rudolf A. de Boer, Natalia López-Andrés, María Miana, Pascal Reboul, Laurent Calvier, Patrick Rossignol

المساهمون: Risque cardiovasculaire, rigidité-fibrose et hypercoagulabilité (RCV), Université Henri Poincaré - Nancy 1 (UHP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Universidad Complutense de Madrid [Madrid] (UCM), Ingénierie Moléculaire et Physiopathologie Articulaire (IMoPA), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Department of Cardiology [UMCG], University Medical Center Groningen [Groningen] (UMCG), Institut Jacques Monod (IJM (UMR_7592)), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Défaillance Cardiovasculaire Aiguë et Chronique (DCAC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Centre d'Investigation Clinique - Epidemiologie Clinique/essais Cliniques Nancy, Cancéropôle du Grand Est-Institut National de la Santé et de la Recherche Médicale (INSERM), Universidad Complutense de Madrid = Complutense University of Madrid [Madrid] (UCM), Cardiovascular Centre (CVC)

المصدر: Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2013, 33 (1), pp.67-75. ⟨10.1161/ATVBAHA.112.300569⟩
Arteriosclerosis thrombosis and vascular biology, 33(1), 67-+. LIPPINCOTT WILLIAMS & WILKINS

مصطلحات موضوعية: Male, MESH: Inflammation, CARDIOTROPHIN-1, Time Factors, Vascular smooth muscle, Galectin 3, SMOOTH-MUSCLE-CELLS, MESH: Collagen Type I, Blood Pressure, 030204 cardiovascular system & hematology, MESH: Mice, Knockout, Muscle, Smooth, Vascular, MESH: Vascular Stiffness, MESH: Hypertension, Muscle hypertrophy, chemistry.chemical_compound, 0302 clinical medicine, Fibrosis, MESH: Up-Regulation, vascular smooth muscle cells, Myocyte, MESH: Animals, Cells, Cultured, Mineralocorticoid Receptor Antagonists, Mice, Knockout, 0303 health sciences, Aldosterone, MESH: Myocytes, Smooth Muscle, [SDV.MHEP.HEM]Life Sciences [q-bio]/Human health and pathology/Hematology, MESH: Muscle, Smooth, Vascular, MESH: Blood Pressure, Up-Regulation, 3. Good health, INSIGHTS, Galectin-3, Hypertension, MESH: Fibrosis, HEART-FAILURE, RNA Interference, medicine.symptom, Cardiology and Cardiovascular Medicine, MESH: Cells, Cultured, EXPRESSION, endocrine system, medicine.medical_specialty, MESH: Rats, Cardiotrophin 1, Myocytes, Smooth Muscle, MESH: RNA Interference, collagen type I, Inflammation, MESH: Mineralocorticoid Receptor Antagonists, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biology, Transfection, 03 medical and health sciences, Vascular Stiffness, LEFT-VENTRICULAR DYSFUNCTION, INFLAMMATION, MESH: Mice, Inbred C57BL, Internal medicine, galectin-3, EXTRACELLULAR-MATRIX, medicine, Animals, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Rats, Wistar, MESH: Mice, 030304 developmental biology, MESH: Humans, aldosterone, MESH: Transfection, MESH: Time Factors, fibrosis, MESH: Aldosterone, MESH: Rats, Wistar, medicine.disease, ENDOTHELIAL-CELLS, MESH: Male, MESH: Galectin 3, Rats, Mice, Inbred C57BL, Disease Models, Animal, MICE, Endocrinology, chemistry, MESH: Disease Models, Animal

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::252478ec7969580e64c626a8c87462bb
https://doi.org/10.1161/atvbaha.112.300569