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المؤلفون: Ira Fleming, Carolyn Winston, Benjamin Kruft, Alex K. Shalek, Wolfram Goessling, Satdarshan P.S. Monga, Florian Mueller, Sungjin Ko, Udayan Apte, Chad Walesky, Kellie E. Kolb, Jake Henderson
المساهمون: Brigham and Women’s Hospital [Boston, MA], Harvard Medical School [Boston] (HMS), Institute of Medical Engineering & Science [Cambridge, MA] (IMES), Massachusetts Institute of Technology (MIT), Broad Institute of MIT and Harvard (BROAD INSTITUTE), Harvard Medical School [Boston] (HMS)-Massachusetts Institute of Technology (MIT)-Massachusetts General Hospital [Boston], Ragon Institute of MGH, MIT and Harvard, Koch Institute for Integrative Cancer Research at MIT [Cambridge, MA], University of Pittsburgh Medical Center [Pittsburgh, PA, États-Unis] (UPMC), Imagerie et Modélisation - Imaging and Modeling, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Centre de Bioinformatique, Biostatistique et Biologie Intégrative (C3BI), Department of Pharmacology, Toxicology, and Therapeutics [Kansas City, KS, USA], University of Kansas Medical Center [Kansas City, KS, USA], Harvard-MIT Division of Health Sciences and Technology [Cambridge], Dana-Farber Cancer Institute [Boston], Harvard Stem Cell Institute [Cambridge, USA] (HSCI), Harvard University, Massachusetts General Hospital [Boston, MA, USA], C..W. is supported by F32DK111151, the Cholangiocarcinoma Foundation Research Fellowship, and the American Liver Foundation Charles Trey, MD Memorial Post-doctoral Research Fellowship. W.G. is supported by R01DK090311, R01DK105198, R24OD017870, and the Claudia Adams Barr Program for Excellence in Cancer Research. W.G. is a Pew Scholar in Biomedical Sciences. A.K.S. was supported, in part, by the Searle Scholars Program, the Beckman Young Investigator Program, a Sloan Fellowship in Chemistry, the NIH (1DP2GM1194192 & RM1HG0061931), and the MIT Stem Cell Initiative through Fondation MIT. U.A. is supported by R01DK098414. S.P.M is supported by NIH/NIDDK P30DK120531, Pittsburgh Liver Research Centre Grant, and NIH/NIDDK (DK62277, DK100287, and CA204586)
المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications, 2020, 11 (1), pp.5785. ⟨10.1038/s41467-020-19558-3⟩مصطلحات موضوعية: 0301 basic medicine, MESH: beta Catenin, General Physics and Astronomy, MESH: Cell Cycle, MESH: Mice, Knockout, Biochemistry, Transcriptome, MESH: Hepatocytes, Mice, 0302 clinical medicine, Protein biosynthesis, MESH: Animals, lcsh:Science, Wnt Signaling Pathway, beta Catenin, Mice, Knockout, Multidisciplinary, Fluorescence in situ hybridization, Cell Cycle, MESH: Wnt Signaling Pathway, Wnt signaling pathway, Cell cycle, MESH: Hepatectomy, Liver regeneration, Cell biology, MESH: Wnt Proteins, Liver, 030211 gastroenterology & hepatology, MESH: Liver Regeneration, Reprogramming, Biotechnology, Science, MESH: Acetaminophen, Biology, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, MESH: Gene Expression Profiling, MESH: Mice, Inbred C57BL, MESH: Cell Proliferation, Detoxification, Genetics, Animals, Hepatectomy, Transcriptomics, MESH: Mice, Molecular Biology, Acetaminophen, Cell Proliferation, Mechanism (biology), Gene Expression Profiling, Macrophages, MESH: Macrophages, General Chemistry, Regenerative process, Liver Regeneration, Gene expression profiling, Mice, Inbred C57BL, Wnt Proteins, Disease Models, Animal, 030104 developmental biology, Hepatocytes, lcsh:Q, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Liver function, MESH: Disease Models, Animal, MESH: Liver
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المؤلفون: Matthieu Ribon, Lorenzo Schiaffino, Christian S Lobsiger, Michel Mallat, Pierre de la Grange, Félix Berriat, Danielle Seilhean, Delphine Bohl, Charlène Iltis, Séverine Boillée, Aude Chiot, Sakina Zaïdi, Ariane Jolly, Stéphanie Millecamps
المساهمون: Institut du Cerveau = Paris Brain Institute (ICM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Università degli studi di Verona = University of Verona (UNIVR), GenoSplice [Paris], Département de Neuropathologie, APHP, Hôpital Pitié-Salpêtrière, Paris, France., CHIOT, Aude
المصدر: Nature Neuroscience
Nature Neuroscience, 2020, 23 (11), pp.1339-1351. ⟨10.1038/s41593-020-00718-z⟩مصطلحات موضوعية: 0301 basic medicine, Therapeutic gene modulation, MESH: Axons, Myeloid, MESH: Mice, Transgenic, [SDV]Life Sciences [q-bio], Cell, Proinflammatory cytokine, MESH: Spinal Cord, 03 medical and health sciences, 0302 clinical medicine, MESH: Mice, Inbred C57BL, medicine, MESH: Animals, Amyotrophic lateral sclerosis, MESH: Amyotrophic Lateral Sclerosis, MESH: Aged, MESH: Middle Aged, MESH: Humans, Microglia, Chemistry, General Neuroscience, Neurodegeneration, MESH: Macrophages, MESH: Adult, medicine.disease, MESH: Male, Cell biology, MESH: Microglia, [SDV] Life Sciences [q-bio], MESH: Sciatic Nerve, 030104 developmental biology, medicine.anatomical_structure, Sciatic nerve, MESH: Female, Neuroscience, MESH: Motor Neurons, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Blanquart, Eve, Mandonnet, Audrey, Mars, Marion, Cenac, Claire, Anesi, Nina, Mercier, Pascale, Audouard, Christophe, Roga, Stephane, Serrano de Almeida, Gilberto, Bevan, Charlotte, Girard, Jean-Philippe, Pelletier, Lucette, Laffont, Sophie, Guéry, Jean-Charles
المساهمون: Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de pharmacologie et de biologie structurale (IPBS), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Centre de biologie du développement (CBD), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Centre de Biologie Intégrative (CBI), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Imperial College London, laffont-pradines, sophie, Toulouse Institute for Infectious and Inflammatory Diseases, University of Toulouse, CNRS, INSERM, UPS, Toulouse, France. (Infinity), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Université Fédérale Toulouse Midi-Pyrénées
المصدر: Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology, 2022, 149 (1), pp.237-251.e12. ⟨10.1016/j.jaci.2021.04.029⟩
Journal of Allergy and Clinical Immunology, Elsevier, 2021, ⟨10.1016/j.jaci.2021.04.029⟩مصطلحات موضوعية: Male, KLRG1, MESH: Signal Transduction, [SDV.IMM] Life Sciences [q-bio]/Immunology, MESH: Lung / pathology, androgen signaling, MESH: Mice, Knockout, [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity, ILC2, MESH: Testosterone / pharmacology, MESH: Pneumonia / immunology, MESH: Mice, Inbred C57BL, Animals, Lectins, C-Type, Testosterone, Sex differences in asthma, MESH: Animals, Lymphocytes, MESH: Pneumonia / pathology, Receptors, Immunologic, [SDV.IMM.ALL]Life Sciences [q-bio]/Immunology/Allergology, Lung, [SDV.IMM.II] Life Sciences [q-bio]/Immunology/Innate immunity, ComputingMilieux_MISCELLANEOUS, Mice, Knockout, Sex Characteristics, lung inflammation, MESH: Androgens / pharmacology, Pneumonia, MESH: Lung / immunology, Interleukin-33, MESH: Receptors, Immunologic / immunology, MESH: Male, Mice, Inbred C57BL, MESH: Lymphocytes / immunology, MESH: Lectins, C-Type / immunology, MESH: Interleukin-33 / immunology, Androgens, [SDV.IMM]Life Sciences [q-bio]/Immunology, Female, MESH: Female, [SDV.IMM.ALL] Life Sciences [q-bio]/Immunology/Allergology, Signal Transduction, MESH: Sex Characteristics
وصف الملف: application/pdf
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المؤلفون: Dimitri Belenki, José Américo N L F de Freitas, Utz Herbig, Maja Milanovic, Oliver Bischof, Jesús Gil, Pierre-François Roux, Bin Sun, Gregory J. Dore, Clemens A. Schmitt, Ricardo Iván Martínez-Zamudio, Lucas Robinson
المساهمون: Institut Pasteur [Paris] (IP), MRC London Institute of Medical Sciences (LMC), Imperial College London, R.I.M.-Z. was supported by La Ligue Nationale Contre le Cancer and is a Mexican National Scientific and Technology Council (CONACYT) and Mexican National Researchers System (SNI) fellow. L.R. was supported by the Pasteur–Paris University (PPU) International Ph.D. Program and by the Fondation pour la Recherche Médicale (FRM). J.A.N.L.F.d.F. was supported by La Ligue Nationale Contre le Cancer. J.G. was supported by the Medical Research Council (MRC, MC_U120085810) and by a grant from Worldwide Cancer Research (WCR, 18-0215). O.B. was supported by the Pasteur–Weizmann Foundation, ANR–BMFT, the Fondation ARC pour la recherche sur le Cancer, La Ligue Nationale Contre le Cancer and INSERM–AGEMED. Research reported in this publication was supported by the National Cancer Institute of the National Institutes of Health under award number R01CA136533., Institut Pasteur [Paris]
المصدر: Nat Cell Biol
Nature Cell Biology
Nature Cell Biology, 2020, 22 (7), pp.842-855. ⟨10.1038/s41556-020-0529-5⟩
Nature Cell Biology, Nature Publishing Group, 2020, 22 (7), pp.842-855. ⟨10.1038/s41556-020-0529-5⟩مصطلحات موضوعية: [SDV]Life Sciences [q-bio], Epigenesis, Genetic, Histones, 0302 clinical medicine, CHROMATIN IMMUNOPRECIPITATION, MESH: Animals, MESH: Epigenesis, Genetic, 11 Medical and Health Sciences, Epigenesis, MESH: Histones, Regulation of gene expression, 0303 health sciences, CELLULAR SENESCENCE, MESH: Gene Expression Regulation, MESH: Transcription Factor AP-1, Chromatin, Cell biology, 030220 oncology & carcinogenesis, Female, Life Sciences & Biomedicine, EXPRESSION, Senescence, PROTEINS, Biology, Article, MESH: Chromatin, 03 medical and health sciences, MESH: Mice, Inbred C57BL, Animals, Humans, Epigenetics, Enhancer, Transcription factor, JUN, 030304 developmental biology, MESH: Humans, Science & Technology, LANDSCAPE, MESH: Transcriptome, MESH: Cellular Senescence, Cell Biology, Epigenome, Fibroblasts, 06 Biological Sciences, Mice, Inbred C57BL, Transcription Factor AP-1, ENHANCERS, Gene Expression Regulation, MESH: Fibroblasts, Transcriptome, MESH: Female, Developmental Biology
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المؤلفون: Pires, Karla, Buffolo, Márcio, Pires, Karla Maria, Ferhat, Maroua, Ilkun, Olesya, Makaju, Aman, Achenbach, Alan, Bowman, Faith, Atkinson, Donald, Holland, William, Amri, Ez-Zoubir, Chaurasia, Bhagirath, Franklin, Sarah, Boudina, Sihem
المساهمون: Institut de Biologie Valrose (IBV), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Cell Reports, Vol 29, Iss 2, Pp 270-282.e5 (2019)
Cell Reports
Cell Reports, Elsevier Inc, 2019, 29 (2), pp.270-282.e5. ⟨10.1016/j.celrep.2019.08.092⟩مصطلحات موضوعية: MESH: Signal Transduction, 0301 basic medicine, MESH: Rosiglitazone, [SDV]Life Sciences [q-bio], visceral fat, MESH: Bone Morphogenetic Protein 4, Adipose tissue, Inflammation, MESH: Muscle, Smooth, MESH: Stem Cells, macromolecular substances, MESH: Phenotype, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Paracrine signalling, 0302 clinical medicine, Insulin resistance, adipose progenitors, MESH: Mice, Inbred C57BL, Fibrosis, medicine, MESH: Animals, MESH: Paracrine Communication, Progenitor cell, cell sorting, MESH: Intra-Abdominal Fat, lcsh:QH301-705.5, Chemistry, technology, industry, and agriculture, MESH: Antigens, CD34, medicine.disease, fat expansion, MESH: Male, humanities, Cell biology, MESH: Solubility, Transplantation, MESH: Insulin Resistance, 030104 developmental biology, MESH: Adipose Tissue, White, lcsh:Biology (General), MESH: Fibroblasts, Adipogenesis, MESH: Weight Gain, medicine.symptom, MESH: Adipogenesis, 030217 neurology & neurosurgery, transplantation
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المؤلفون: Scekic-Zahirovic, Jelena, Sanjuan-Ruiz, Inmaculada, Kan, Vanessa, Megat, Salim, De Rossi, Pierre, Dieterlé, Stéphane, Cassel, Raphaelle, Jamet, Marguerite, Kessler, Pascal, Wiesner, Diana, Tzeplaeff, Laura, Demais, Valérie, Sahadevan, Sonu, Hembach, Katharina M, Muller, Hans-Peter, Picchiarelli, Gina, Mishra, Nibha, Antonucci, Stefano, Dirrig-Grosch, Sylvie, Kassubek, Jan, Rasche, Volker, Ludolph, Albert, Boutillier, Anne-Laurence, Roselli, Francesco, Polymenidou, Magdalini, Lagier-Tourenne, Clotilde, Liebscher, Sabine, Dupuis, Luc
المساهمون: Mécanismes Centraux et Périphériques de la Neurodégénérescence, Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Ludwig-Maximilians University [Munich] (LMU), Universität Zürich [Zürich] = University of Zurich (UZH), Laboratoire de neurosciences cognitives et adaptatives (LNCA), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), CRBS - Centre de Recherche en Biomédecine de Strasbourg (Inserm UMS38/UNISTRA), University of Ulm (UUlm), Deutsches Zentrum für Neurodegenerative Erkrankungen [Ulm] (DZNE), German Research Center for Neurodegenerative Diseases - Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Centre de Neurochimie, Harvard Medical School [Boston] (HMS), Harvard University [Cambridge], Munich Cluster for systems neurology [Munich] (SyNergy), Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM)-Ludwig-Maximilians-Universität München (LMU), Université de Strasbourg Inserm Faculté de médecine, Klinikum der Universitat Munchen, Ludwig-Maximilians-Universität München (LMU), University hospital of Zurich [Zurich], Universität Ulm - Ulm University [Ulm, Allemagne], Massachusetts Institute of Technology (MIT), Ludwig-Maximilians University Hospital (LMU Munich), ANR-16-CE92-0031,EpiFUS,Rôle de FUS dans la régulation des modifications épigénétiques : conséquences pour la sclérose latérale amyotrophique et la démence frontotemporale(2016), ANR-16-CE16-0015,ToFU,Interactions entre TAU, FUS et TDP-43 dans les maladies neurodégénératives(2016), ANR-19-CE17-0016,SPREADALS,Propagation et toxicité des facteurs pathogéniques de la sclérose latérale amyotrophique(2019), Technische Universität München [München] (TUM)-Ludwig-Maximilians-Universität München (LMU), Anne Laurence, Boutillier, Rôle de FUS dans la régulation des modifications épigénétiques : conséquences pour la sclérose latérale amyotrophique et la démence frontotemporale - - EpiFUS2016 - ANR-16-CE92-0031 - AAPG2016 - VALID, Interactions entre TAU, FUS et TDP-43 dans les maladies neurodégénératives - - ToFU2016 - ANR-16-CE16-0015 - AAPG2016 - VALID, Propagation et toxicité des facteurs pathogéniques de la sclérose latérale amyotrophique - - SPREADALS2019 - ANR-19-CE17-0016 - AAPG2019 - VALID, University of Zurich, Liebscher, Sabine, Dupuis, Luc, Centre de Recherche en Biomédecine de Strasbourg (CRBS), Dieterle, Stéphane
المصدر: Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.3028. ⟨10.1038/s41467-021-23187-9⟩
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications 12(1), 3028 (2021). doi:10.1038/s41467-021-23187-9
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-23187-9⟩
Nature Communications, 2021, 12 (1), ⟨10.1038/s41467-021-23187-9⟩
Nature Communications, 2021, 12 (1), pp.3028. ⟨10.1038/s41467-021-23187-9⟩مصطلحات موضوعية: Male, Cytoplasm, [SDV]Life Sciences [q-bio], General Physics and Astronomy, Gene Expression, Synaptic Transmission, MESH: Synapses, Mice, MESH: Animals, Gene Knock-In Techniques, MESH: Amyotrophic Lateral Sclerosis, MESH: Gene Knock-In Techniques, metabolism [RNA-Binding Protein FUS], Motor Neurons, MESH: RNA-Binding Protein FUS, FUS protein, mouse, 3100 General Physics and Astronomy, [SDV] Life Sciences [q-bio], genetics [Amyotrophic Lateral Sclerosis], Phenotype, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Female, ddc:500, MESH: Motor Neurons, MESH: Mutation, MESH: Gene Expression, Science, 610 Medicine & health, 1600 General Chemistry, Genetics and Molecular Biology, MESH: Phenotype, Article, 1300 General Biochemistry, Genetics and Molecular Biology, MESH: Mice, Inbred C57BL, MESH: Synaptic Transmission, Animals, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], MESH: Mice, metabolism [Cytoplasm], metabolism [Amyotrophic Lateral Sclerosis], MESH: Cytoplasm, Amyotrophic Lateral Sclerosis, General Chemistry, metabolism [Motor Neurons], metabolism [Synapses], MESH: Male, Mice, Inbred C57BL, physiology [Synaptic Transmission], General Biochemistry, Mutation, Synapses, RNA-Binding Protein FUS, 11493 Department of Quantitative Biomedicine, genetics [RNA-Binding Protein FUS], MESH: Female
وصف الملف: application/pdf; 2021_NatureCummun.pdf - application/pdf
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المؤلفون: Rozier, Pauline, Maumus, Marie, Maria, Alexandre Thibault Jacques, Toupet, Karine, Jorgensen, Christian, Guilpain, Philippe, Noël, Danièle
المساهمون: Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Service de Rhumatologie [CHRU Montpellier], Salvy-Córdoba, Nathalie
المصدر: Cells
Volume 10
Issue 10
Cells, Vol 10, Iss 2727, p 2727 (2021)
Cells, MDPI, 2021, 10 (10), pp.2727. ⟨10.3390/cells10102727⟩مصطلحات موضوعية: MESH: Interferon-gamma, QH301-705.5, Pulmonary Fibrosis, Anti-Inflammatory Agents, exosomes, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, MESH: Scleroderma, Systemic, MESH: Immunosuppression Therapy, Article, Interferon-gamma, MESH: Skin, MESH: Mice, Inbred C57BL, MESH: Up-Regulation, Animals, MESH: Animals, scleroderma, MESH: Extracellular Vesicles, Biology (General), Skin, Immunosuppression Therapy, [SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, therapy, Scleroderma, Systemic, MESH: Pulmonary Fibrosis, Mesenchymal Stem Cells, [SDV.IMM.IMM]Life Sciences [q-bio]/Immunology/Immunotherapy, Up-Regulation, Mice, Inbred C57BL, MicroRNAs, MESH: Mesenchymal Stem Cells, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, MESH: Anti-Inflammatory Agents, mesenchymal stromal cell, [SDV.MHEP.PSR] Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, [SDV.IMM.IMM] Life Sciences [q-bio]/Immunology/Immunotherapy, extracellular vesicles, MESH: MicroRNAs, microvesicles
وصف الملف: application/pdf
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المؤلفون: Vishukumar Aimanianda, Jacob L. Steenwyk, Agostinho Carvalho, Cláudio Duarte-Oliveira, Laure Nicolas Annick Ries, Fernando Rodrigues, Fausto Almeida, Taicia Pacheco Fill, Antonis Rokas, Lilian Pereira Silva, Patrícia Alves de Castro, Iola F. Duarte, Sarah Sze Wah Wong, Jonas Henrique Costa, Gustavo H. Goldman, Clara Valero, Relber Aguiar Gonçales, Raquel Saborano, Gabriela F. Persinoti, Thaila Fernanda dos Reis
المساهمون: Universidade de São Paulo = University of São Paulo (USP), University of Birmingham [Birmingham], Universidade de Aveiro, Centro Nacional de Pesquisa em Energia e Materiais = Brazilian Center for Research in Energy and Materials (CNPEM), Vanderbilt University [Nashville], Universidade Estadual de Campinas = University of Campinas (UNICAMP), Mycologie moléculaire - Molecular Mycology, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Universidade do Minho = University of Minho [Braga], Life and Health Sciences Research Institute [Braga] (ICVS), University of Minho [Braga], We thank Universidade do Minho, Portugal and Universidade do São Paulo, Brazil for providing support for the scientific collaboration (G.H.G. and A.C., Edital USP-UMinho 2019). We thank the São Paulo Research Foundation (Fundacao de Amparo a Pesquisa do Estado de Sao Paulo [FAPESP], Brazil) grants 2017/14159-2 (L.N.A.R.), 2016/12948-7 (P.A.D.C.), 2017/08750-0 (T.F.D.R.), 2016/07870-9 (G.H.G.), 2018/00715-3 (C.V.), and the Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brazil (CNPq) grants 301058/2019-9 and 404735/2018-5 (G.H.G.) for financial support. I.F.D. acknowledges CICECO-Aveiro Institute of Materials (UIDB/50011/2020 and UIDP/50011/2020) financed by national funds through the Foundation for Science and Technology/MCTES, and the National NMR Network (PTNMR) partially supported by Infrastructure Project 022161 (cofinanced by FEDER through COMPETE 2020, POCI and PORL and FCT through PIDDAC). A.C., R.A.G., and C.D.-O. were supported by the Fundação para a Ciência e a Tecnologia (FCT) (PTDC/MED-GEN/28778/2017, UIDB/50026/2020, and UIDP/50026/2020). Additional support was provided by the Northern Portugal Regional Operational Program (NORTE 2020), under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (ERDF) (NORTE-01-0145-FEDER-000013 and NORTE-01-0145-FEDER-000023), the European Union’s Horizon 2020 research and innovation program under grant agreement 847507, and the 'la Caixa' Foundation (ID 100010434) and FCT under the agreement LCF/PR/HP17/52190003. Individual support was provided by FCT (SFRH/BD/141127/2018 to C.D.-O., and CEECIND/03628/2017 to A.C.). This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001 (J.H.C. scholarship). S.S.W.W. was supported by Pasteur-Roux-Cantarini fellowship. J.L.S. and A.R. are supported by the Howard Hughes Medical Institute through the James H. Gilliam Fellowships for Advanced Study program, A.R. is additionally supported by the National Institutes of Health/National Institute of Allergy and Infectious Diseases (1R56AI146096-01A1)., European Project: 847507,H2020-SC1-2019-Two-Stage-RTD,HDM-FUN(2020)
المصدر: mBio
mBio, 2021, 12 (4), pp.e0168221. ⟨10.1128/mBio.01682-21⟩
mBio, Vol 12, Iss 4 (2021)مصطلحات موضوعية: Male, Neutrophils, Secondary Metabolism, Acetates, Moths, MESH: Neutrophils, MESH: Virulence, Aspergillus fumigatus, Mice, Gene Expression Regulation, Fungal, MESH: Animals, skin and connective tissue diseases, transcription factor, [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, 0303 health sciences, Virulence, biology, secondary metabolites, MESH: Moths, QR1-502, MESH: Secondary Metabolism, Phenotype, Larva, acetate assimilation, MESH: Fungal Proteins, MESH: Acetates, MESH: Aspergillus fumigatus, Acetate utilization, MESH: Gene Expression Regulation, Fungal, Research Article, MESH: Phenotype, Microbiology, Fungal Proteins, 03 medical and health sciences, MESH: Mice, Inbred C57BL, Virology, Animals, Aspergillosis, Humans, MESH: Aspergillosis, Transcription factor, MESH: Mice, 030304 developmental biology, Final version, MESH: Humans, 030306 microbiology, biology.organism_classification, Pathogenicity, MESH: Male, Mice, Inbred C57BL, cell wall, MESH: Larva
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e21be1b24f840e2b7c2cf74161b5bf7a
https://hal.science/hal-03928997/file/mBio.01682-21.pdf -
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المؤلفون: Sophie Vinoy, Carlito B. Lebrilla, Jeffrey I. Gordon, Kyleigh Kirbach, Andrew C. Heath, Bernard Henrissat, Chandani Desai, Juan Jose Castillo, Ruteja A. Barve, Omar Delannoy-Bruno, Arjun S. Raman, Robert Y. Chen, David K. Hayashi, Andrei L. Osterman, Semen A. Leyn, Nathan D. Han, Jiye Cheng, Matthew C. Hibberd, Dmitry A. Rodionov, Alexandra Meynier, Garret Couture, Vincent Lombard, Tara Wilmot, Samuel Klein, Michael J. Barratt
المساهمون: Architecture et fonction des macromolécules biologiques (AFMB), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
المصدر: Nature
Nature, Nature Publishing Group, 2021, 595 (7865), pp.91-95. ⟨10.1038/s41586-021-03671-4⟩
Nature, vol 595, iss 7865
Nature, 2021, 595 (7865), pp.91-95. ⟨10.1038/s41586-021-03671-4⟩مصطلحات موضوعية: 0301 basic medicine, Dietary Fiber, Male, Proteome, [SDV]Life Sciences [q-bio], Disease, Overweight, MESH: Bacteroides, Inbred C57BL, Cardiovascular, Oral and gastrointestinal, Feces, Mice, 0302 clinical medicine, MESH: Blood Proteins, Bacteroides, MESH: Obesity, MESH: Animals, Food science, Cancer, 2. Zero hunger, Multidisciplinary, MESH: Middle Aged, Human studies, digestive, oral, and skin physiology, MESH: Feces, Blood Proteins, Middle Aged, 3. Good health, Stroke, MESH: Proteome, MESH: Young Adult, Female, Zero Hunger, medicine.symptom, MESH: Snacks, Adult, Adolescent, General Science & Technology, Biology, MESH: Gastrointestinal Microbiome, 03 medical and health sciences, Young Adult, MESH: Mice, Inbred C57BL, Controlled diets, MESH: Germ-Free Life, medicine, Animals, Humans, Germ-Free Life, Microbiome, Obesity, MESH: Overweight, MESH: Mice, Metabolic and endocrine, Nutrition, MESH: Adolescent, MESH: Humans, Prevention, Dietary fibre, MESH: Adult, medicine.disease, MESH: Male, Gastrointestinal Microbiome, 030104 developmental biology, MESH: Dietary Fiber, Snacks, MESH: Female, 030217 neurology & neurosurgery
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المؤلفون: Pierre De Rossi, Marian Hruska-Plochan, Magdalini Polymenidou, Mark D. Robinson, Elena Tantardini, Luc Dupuis, Salim Megat, Julien Weber, Katharina M. Hembach, Petra Schwarz, Sonu Sahadevan, Manuela Pérez-Berlanga
المساهمون: Universität Zürich [Zürich] = University of Zurich (UZH), Mécanismes Centraux et Périphériques de la Neurodégénérescence, Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), University hospital of Zurich [Zurich], Dieterle, Stéphane, University of Zurich, Polymenidou, Magdalini
المصدر: Nature Communications
Nature Communications, 2021, 12 (1), pp.3027. ⟨10.1038/s41467-021-23188-8⟩
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.3027. ⟨10.1038/s41467-021-23188-8⟩مصطلحات موضوعية: 0301 basic medicine, [SDV]Life Sciences [q-bio], General Physics and Astronomy, MESH: Synapses, Synapse, Mice, 0302 clinical medicine, MESH: Animals, Amyotrophic lateral sclerosis, MESH: Amyotrophic Lateral Sclerosis, Cerebral Cortex, Multidisciplinary, MESH: RNA-Binding Protein FUS, Neurodegeneration, 10124 Institute of Molecular Life Sciences, 3100 General Physics and Astronomy, Cell biology, [SDV] Life Sciences [q-bio], GABAergic, Microtubule-Associated Proteins, MESH: Cell Nucleus, Science, 1600 General Chemistry, Genetics and Molecular Biology, Biology, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, 1300 General Biochemistry, Genetics and Molecular Biology, MESH: Mice, Inbred C57BL, MESH: RNA, medicine, Animals, RNA, Messenger, Synapse organization, MESH: Mice, MESH: RNA, Messenger, RNA metabolism, Cell Nucleus, Messenger RNA, Amyotrophic Lateral Sclerosis, RNA, General Chemistry, medicine.disease, MESH: Cerebral Cortex, Mice, Inbred C57BL, MESH: Microtubule-Associated Proteins, Disease Models, Animal, 030104 developmental biology, General Biochemistry, Synapses, 570 Life sciences, biology, RNA-Binding Protein FUS, MESH: Disease Models, Animal, 11493 Department of Quantitative Biomedicine, 030217 neurology & neurosurgery, Nuclear localization sequence
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