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المؤلفون: Steven B. Blanchard, Cécile Méjécase, Thierry Léveillard, Sandra Chantot-Bastaraud, Marion Neuillé, Christelle Michiels, Saddek Mohand-Said, Elise Orhan, Christina Zeitz, Juliette Wohlschlegel, Frédéric Blond, Audrey Schalk, Sébastien Augustin, Christel Condroyer, Amrit Estivalet, Lisa Emmenegger, Aline Antonio, Vanessa Démontant, Crystel Bonnet, José-Alain Sahel, Camille Andrieu, Isabelle Audo, Marine Foussard
المساهمون: Institut de la Vision, Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts (CHNO), Institut de l'Audition [Paris] (IDA), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Genopole Research, Fondation Ophtalmologique Adolphe de Rothschild [Paris], Maladies génétiques d'expression pédiatrique [CHU Trousseau] (Inserm U933), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), UF de Génétique chromosomique [CHU Trousseau], CHU Trousseau [APHP], Académie des Sciences [Paris], Institut de France, Department of Ophthalmology [Pittsburgh, PA, États-Unis], University of Pittsburgh School of Medicine [Pittsburgh, PA, États-Unis], University of Pittsburgh Medical Center [Pittsburgh, PA, États-Unis] (UPMC)-University of Pittsburgh Medical Center [Pittsburgh, PA, États-Unis] (UPMC), Institute of Ophthalmology [London], University College of London [London] (UCL), This research was funded by Fondation Voir et Entendre (CZ), Prix Dalloz for 'La recherche en ophtalmologie' (CZ), LABEX LIFESENSES (reference ANR-10-LABX-65) supported by French state funds managed by the Agence Nationale de la Recherche within the Investissements d’Avenir program (ANR-11-IDEX-0004-0), IHU FOReSIGHT (ANR-18-IAHU-0001) supported by French state funds managed by the Agence Nationale de la Recherche within the Investissements d’Avenir program, Foundation Fighting Blindness center grant [C-CMM-0907-0428-INSERM04], grant (BR-GE-0619-0761-INSERM) Prix de la Fondation de l’Œil (IA), UNADEV (Union Nationale des Aveugles et Déficients Visuels) in partnership with ITMO NNP/AVIESAN (alliance nationale pour les sciences de la vie et de la santé) for research in visual disorders, and doctoral funding from the Ministère de l’Enseignement Supérieur et de la Recherche (MESR) and Fondation de France (CM)., ANR-10-LABX-0065,LIFESENSES,DES SENS POUR TOUTE LA VIE(2010), ANR-11-IDEX-0004,SUPER,Sorbonne Universités à Paris pour l'Enseignement et la Recherche(2011), ANR-18-IAHU-0001,FOReSIGHT,Enabling Vision Restoration(2018), Couvet, Sandrine, DES SENS POUR TOUTE LA VIE - - LIFESENSES2010 - ANR-10-LABX-0065 - LABX - VALID, Sorbonne Universités à Paris pour l'Enseignement et la Recherche - - SUPER2011 - ANR-11-IDEX-0004 - IDEX - VALID, Enabling Vision Restoration - - FOReSIGHT2018 - ANR-18-IAHU-0001 - IAHU - VALID, Maladies génétiques d'expression pédiatrique (U933), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)
المصدر: International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences, 2021, 22 (15), pp.7875. ⟨10.3390/ijms22157875⟩
International Journal of Molecular Sciences, Vol 22, Iss 7875, p 7875 (2021)مصطلحات موضوعية: 0301 basic medicine, Male, Candidate gene, retina, Potassium Channels, [SDV]Life Sciences [q-bio], mitochondrial protein, 030105 genetics & heredity, Mitochondrion, medicine.disease_cause, Gene duplication, Biology (General), Spectroscopy, Genetics, Mutation, inner segments, MESH: Mitochondrial Proteins, General Medicine, MESH: Potassium Channels, Computer Science Applications, Pedigree, MESH: Cone-Rod Dystrophies, [SDV] Life Sciences [q-bio], Chemistry, Phenotype, Female, rod-cone dystrophy, Adult, MESH: Mutation, QH301-705.5, MESH: Pedigree, Genes, Recessive, Biology, [SDV.GEN.GH] Life Sciences [q-bio]/Genetics/Human genetics, MESH: Phenotype, CCDC51, Catalysis, Article, Frameshift mutation, Inorganic Chemistry, Mitochondrial Proteins, 03 medical and health sciences, retinitis pigmentosa, Retinitis pigmentosa, medicine, Rod-cone dystrophy, Humans, Physical and Theoretical Chemistry, QD1-999, Molecular Biology, Gene, MESH: Genes, Recessive, MESH: Humans, Organic Chemistry, MITOK, candidate gene, MESH: Adult, medicine.disease, MESH: Male, 030104 developmental biology, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, MESH: Female, Cone-Rod Dystrophies
وصف الملف: application/pdf
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المؤلفون: Tobias Sahr, Platon L, Dramé M, Pedro Escoll, Carmen Buchrieser, Christophe Rusniok, Silke Schmidt
المساهمون: Biologie des Bactéries intracellulaires - Biology of Intracellular Bacteria, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Université de Montpellier (UM), Université de Paris (UP), Collège doctoral [Sorbonne universités], Sorbonne Université (SU), This research was funded by the Institut Pasteur, DARRI - Institut Carnot - Microbe et santé (grant number INNOV-SP10-19) to PE, the Agence National de Recherche (grant number ANR-10-LABX- 62-IBEID) and the Fondation de la Recherché Médicale (FRM) (grant number EQU201903007847) to CB, and the Région Ile-de-France (program DIM1Health) to PBI (part of FranceBioImaging, ANR-10-INSB-04-01). MD was supported by the Ecole Doctorale FIRE – 'Programme Bettencourt'. SS was supported by the Pasteur Paris-University (PPU) International PhD Program., We acknowledge C.B.’s, P. Glaser’s lab members and F. Stavru at Institut Pasteur for fruitful discussions. We thank N. Aulner, A. Danckaert, Photonic BioImaging (PBI) UTechS and M. Hassan, Center for Translational Science (CRT) at Institut Pasteur, for support, ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-10-INBS-0004,France-BioImaging,Développment d'une infrastructure française distribuée coordonnée(2010), Université Paris Cité (UPCité)-Microbiologie Intégrative et Moléculaire (UMR6047), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Mémoires - Université de Montpellier - Faculté des sciences (UM FS), Faculté des sciences de Paris, Université de Paris (1896-1970), Collège Doctoral, This research was funded by the Institut Pasteur, DARRI-Institut Carnot-Microbe et santé (grant number INNOV-SP10-19) to PE, the Agence National de Recherche (grant number ANR-10-LABX-62-IBEID to CB and ANR-21-CE15-0038-01 to PE), the Fondation de la Recherché Médicale (FRM) (grant number EQU201903007847) to CB, and the Région Ile-de-France (program DIM1Health) to PBI (part of FranceBioImaging, ANR-10-INSB-04–01). MD was supported by the Ecole Doctorale FIRE – 'Programme Bettencourt.' SS was supported by the Pasteur Paris-University (PPU) International PhD Program., We acknowledge CB’s, P Glaser’s lab members, and F Stavru at Institut Pasteur for fruitful discussions. We specially thank Daniel Schator for help and discussions regarding HEK-293 infection and transfec- tion. We thank N Aulner, A Danckaert, Photonic BioImaging (PBI) UTechS and M Hassan, Center for Translational Science (CRT) at Institut Pasteur, for support., ANR-21-CE15-0038,MITOBAC,Interactions Métaboliques Hôte-Pathogène: Comment des Bactéries Intracellulaires détournent l'OXPHOS Mitochondriale pendant l'infection(2021), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Université Paris Cité (UPCité)
المصدر: eLife
eLife, 2021, 10, ⟨10.7554/eLife.71978⟩
eLife, Vol 10 (2021)مصطلحات موضوعية: Programmed cell death, QH301-705.5, MESH: Mitochondria, Science, infectious disease, FOF1-ATPase, Oxidative phosphorylation, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biology, Legionella pneumophila, MESH: Proton-Translocating ATPases, 03 medical and health sciences, 0302 clinical medicine, mitochondrial membrane potential, MESH: Adenosine Triphosphate, Biology (General), MESH: Bacterial Proteins, MESH: Type IV Secretion Systems, 030304 developmental biology, Membrane potential, 0303 health sciences, Effector, microbiology, MESH: Mitochondrial Proteins, Metabolism, Microphthalmia-associated transcription factor, biology.organism_classification, MESH: Legionella pneumophila, OXPHOS, 3. Good health, Cell biology, macrophages, mitochondria, cell death, Medicine, Reprogramming, 030217 neurology & neurosurgery
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المؤلفون: Alžběta Motyčková, Čestmír Vlček, Vladimír Klimeš, B. Franz Lang, Michael W. Gray, Zuzana Vaitová, Anastasios D. Tsaousis, Tomáš Pánek, Ingrid Guilvout, Marek Eliáš, Romain Derelle, Vojtěch Žárský, Markéta Petrů, Mohamed Chami, Karel Harant, Lenka Horváthová, Jan Pyrih, Olivera Francetic, Luboš Voleman, Pavel Doležal, Lenka Marková, Veronika Klápšťová, Ivan Čepička, Klára Hryzáková, Martina Vinopalová
المساهمون: Dpt of Parasitology [Prague], Charles University [Prague] (CU), Ostravská univerzita / University of Ostrava, University of Birmingham [Birmingham], University of Kent [Canterbury], Czech Academy of Sciences [Prague] (CAS), Faculty of Medicine [Brno] (MED / MUNI), Masaryk University [Brno] (MUNI), Dalhousie University [Halifax], Center for Cellular Imaging and Nanoanalytics, University of Basel (Unibas), Biochimie des Interactions Macromoléculaires / Biochemistry of Macromolecular Interactions, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Université de Montréal (UdeM), This work was supported by Czech Science Foundation grants 13-29423S to P.D. and 18-18699S to M.E., and the KONTAKT II grant LH15253 provided by Ministry of Education, Youth and Sports of CR (MEYS) to P.D., This work was also supported by MEYS within the National Sustainability Program II (Project BIOCEV-FAR, LQ1604) the project BIOCEV (CZ.1.05/1.1.00/02.0109), and the project 'Centre for research of pathogenicity and virulence of parasites' (No. CZ.02.1.01/0.0/0.0/16_019/0000759) funded by European Regional Development Fund (ERDF) and MEYS and by Moore-Simons Project on the Origin of the Eukaryotic Cell to P.D. https://doi.org/10.37807/GBMF9738, The work in the OF laboratory was funded by the ANR-14-CE09-0004 grant. J.P. was supported by a grant from the Gordon and Betty Moore Foundation to ADT. This work was supported by The Ministry of Education, Youth and Sports from the Large Infrastructures for Research, Experimental Development and Innovations project 'IT4Innovations National Supercomputing Center – LM2015070'., ANR-14-CE09-0004,FiberSpace,Pili de type IV et pseudopili: structure, dynamique, assemblage et fonction moléculaire(2014), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2947. ⟨10.1038/s41467-021-23046-7⟩
Nature Communications, 2021, 12 (1), pp.2947. ⟨10.1038/s41467-021-23046-7⟩
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)مصطلحات موضوعية: Models, Molecular, Protein family, MESH: Mitochondria, MESH: Sequence Homology, Amino Acid, Science, [SDV]Life Sciences [q-bio], Protozoan Proteins, MESH: Amino Acid Sequence, Mitochondrion, Biology, MESH: Naegleria, Models, Biological, Article, Evolutionary genetics, Evolution, Molecular, Mitochondrial Proteins, Gram-Negative Bacteria, Type II Secretion Systems, parasitic diseases, MESH: Gram-Negative Bacteria, Peroxisomes, Secretion, Amino Acid Sequence, MESH: Phylogeny, MESH: Protozoan Proteins, Conserved Sequence, Phylogeny, MESH: Evolution, Molecular, Sequence (medicine), Genetics, MESH: Type II Secretion Systems, Protein translocation, MESH: Conserved Sequence, Sequence Homology, Amino Acid, Phylogenetic tree, Type II secretion system, fungi, MESH: Models, Biological, Eukaryota, MESH: Mitochondrial Proteins, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Naegleria, Peroxisome, MESH: Peroxisomes, Mitochondria, MESH: Eukaryota, Bacterial outer membrane, MESH: Models, Molecular
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المؤلفون: Catherine Brenner, Kostas Tokatlidis, Nazanine Modjtahedi, Ruairidh Edwards, Kenza Nedara, Giuseppe Arena, Camille Reinhardt
المساهمون: Radiothérapie Moléculaire et Innovation Thérapeutique (RaMo-IT), Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Aspects métaboliques et systémiques de l'oncogénèse pour de nouvelles approches thérapeutiques (METSY), Institut Gustave Roussy (IGR)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut Gustave Roussy (IGR), Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Signalisation et physiopathologie cardiaque, Université Paris-Sud - Paris 11 (UP11)-IFR141-Institut National de la Santé et de la Recherche Médicale (INSERM), Modjtahedi, Nazanine
المصدر: Biochimica et Biophysica Acta-Molecular Basis of Disease
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2020, 1866 (6), pp.165746. ⟨10.1016/j.bbadis.2020.165746⟩
Biochimica et Biophysica Acta-Molecular Basis of Disease, 2020, 1866 (6), pp.165746. ⟨10.1016/j.bbadis.2020.165746⟩مصطلحات موضوعية: 0301 basic medicine, Apoptosis Inducing Factor/genetics/metabolism, [SDV]Life Sciences [q-bio], Respiratory chain, Mitochondrion, Biochemistry, biophysics & molecular biology [F05] [Life sciences], Mitochondrial Membrane Transport Proteins, Respiratory chain machinery, 0302 clinical medicine, Mitochondrial Precursor Protein Import Complex Proteins, Disulfides, Biochimie, biophysique & biologie moléculaire [F05] [Sciences du vivant], MESH: Electron Transport Complex I, Chemistry, Apoptosis Inducing Factor, MESH: Mitochondrial Proteins, Translation (biology), MESH: Mitochondrial Membrane Transport Proteins, MESH: Saccharomyces cerevisiae, MESH: Gene Expression Regulation, Mitochondrial protein import, Cell biology, Mitochondria, [SDV] Life Sciences [q-bio], Electron Transport Complex I/genetics/metabolism, Protein Transport, Disulfides/metabolism, 030220 oncology & carcinogenesis, Mitochondrial Proteins/genetics, Molecular Medicine, Intermembrane space, Saccharomyces cerevisiae/genetics/metabolism, Disulfide relay system, MESH: Protein Transport, MESH: Mutation, Mutation/genetics, MESH: Mitochondria, Protein subunit, Saccharomyces cerevisiae, Mitochondrial Proteins, 03 medical and health sciences, Downregulation and upregulation, Humans, MESH: Disulfides, Cysteine, Molecular Biology, Mitochondria/genetics/metabolism, Electron Transport Complex I, MESH: Humans, Protein Transport/genetics, MESH: Cysteine, Cysteine/genetics/metabolism, 030104 developmental biology, MESH: Apoptosis Inducing Factor, Metabolism, Gene Expression Regulation, Mutation, Mitochondrial Membrane Transport Proteins/genetics, Function (biology), Biogenesis
وصف الملف: application/pdf
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المؤلفون: Mariette Matondo, Pascale Cossart, Filipe Carvalho, Fabrizia Stavru, Anna Spier, T. Chaze
المساهمون: Interactions Bactéries-Cellules (UIBC), Institut National de la Recherche Agronomique (INRA)-Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris Diderot - Paris 7 (UPD7), Spectrométrie de Masse pour la Biologie – Mass Spectrometry for Biology (UTechS MSBio), Institut Pasteur [Paris]-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), This study was supported by grants to P.C. from the European Research Council (H2020-ERC-2014-409ADG 670823-BacCellEpi), the Agence Nationale de la Recherche (ANR) and the French Government’s 'Investissements d’Avenir' program Laboratoires d’Excellence 'Integrative Biology of Emerging Infectious Diseases' (LabEx IBEID, ANR-10-LABX-62-IBEID). A.S. was supported by a BioSPC doctoral fellowship from the Université Paris Diderot. P.C. is a Senior International Research Scholar of the Howard Hughes Medical Institute. F.S. is a CNRS permanent researcher, We thank current and past lab members for helpful discussions, Francis Impens and Evy Timmerman (VIB Proteomics Core, University of Ghent, Belgium) for training and assistance with proteomic analyses, and Alessandro Pagliuso for critical reading of the manuscript, ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), European Project: 670823,H2020,ERC-2014-ADG,BacCellEpi(2015), Centre National de la Recherche Scientifique (CNRS)-Centre de Ressources et de Recherche Technologique - Center for Technological Resources and Research (C2RT), Institut Pasteur [Paris]-Institut Pasteur [Paris], ANR-10-LABX-62-IBEID,IBEID,Laboratoire d'Excellence 'Integrative Biology of Emerging Infectious Diseases'(2010), Institut National de la Recherche Agronomique (INRA)-Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris] (IP)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Stavru, Fabrizia, Integrative Biology of Emerging Infectious Diseases - - IBEID2010 - ANR-10-LABX-0062 - LABX - VALID, Bacterial, cellular and epigenetic factors that control enteropathogenicity - BacCellEpi - - H20202015-10-01 - 2018-09-30 - 670823 - VALID, Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur [Paris]-Institut National de la Recherche Agronomique (INRA)
المصدر: mBio
mBio, American Society for Microbiology, 2020, 11 (1), ⟨10.1128/mBio.03171-19⟩
mBio, 2020, 11 (1), ⟨10.1128/mBio.03171-19⟩مصطلحات موضوعية: Mic10, MESH: HCT116 Cells, MESH: Mitochondria, [SDV]Life Sciences [q-bio], [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Mitochondrion, Biology, MESH: Listeria monocytogenes, medicine.disease_cause, 03 medical and health sciences, proteomics, 0302 clinical medicine, Listeria monocytogenes, Organelle, MESH: Up-Regulation, medicine, Inner mitochondrial membrane, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, [SDV.MP] Life Sciences [q-bio]/Microbiology and Parasitology, 030304 developmental biology, 0303 health sciences, MESH: Humans, MICOS complex, mitochondrial fission, MESH: Proteomics, Listeriolysin O, MESH: Mitochondrial Proteins, MESH: Mitochondrial Dynamics, Cell biology, [SDV] Life Sciences [q-bio], [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Mitochondrial fission, MESH: Membrane Proteins, 030217 neurology & neurosurgery, Intracellular
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e9e3457ca897166d9cfa7bbc722cc9
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المؤلفون: Thomas, James A., Baker, Nicola, Hutchinson, Sebastian, Dominicus, Caia, Trenaman, Anna, Glover, Lucy, Alsford, Sam, Horn, David
المساهمون: London School of Hygiene and Tropical Medicine (LSHTM), University of York [York, UK], Institut Pasteur [Paris], The Francis Crick Institute [London], University of Dundee, We thank Philippa Radley for assistance with assembly of tagging constructs, Richard Wheeler (Uni. of Oxford) for advice on ImageJ analysis and Achim Schnaufer (Uni. of Edinburgh) for the ATP-synthase antibody, Institut Pasteur [Paris] (IP)
المصدر: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Public Library of Science, 2018, 12 (11), pp.e0006980. ⟨10.1371/journal.pntd.0006980⟩
PLoS Neglected Tropical Diseases, Vol 12, Iss 11, p e0006980 (2018)
PLoS Neglected Tropical Diseases, 2018, 12 (11), pp.e0006980. ⟨10.1371/journal.pntd.0006980⟩مصطلحات موضوعية: Physiology, [SDV]Life Sciences [q-bio], RC955-962, Melarsoprol, MESH: Melarsoprol, Biochemistry, Arctic medicine. Tropical medicine, Medicine and Health Sciences, Cell Cycle and Cell Division, MESH: Trypanocidal Agents, Energy-Producing Organelles, Protozoans, Chromosome Biology, Pharmaceutics, Eukaryota, MESH: Mitochondrial Proteins, Trypanocidal Agents, Mitochondria, Electrophysiology, Nucleic acids, Cell Processes, MESH: Pentamidine, Cellular Structures and Organelles, Public aspects of medicine, RA1-1270, Research Article, Trypanosoma, MESH: Mitochondria, Trypanosoma brucei brucei, Mitosis, Suramin, Bioenergetics, DNA replication, Membrane Potential, MESH: Cell Biology, Mitochondrial Proteins, Drug Therapy, parasitic diseases, Trypanosoma Brucei, Genetics, Humans, MESH: Suramin, Pentamidine, MESH: Humans, MESH: Nifurtimox, Organisms, Biology and Life Sciences, MESH: Trypanosoma brucei brucei, Cell Biology, DNA, MESH: Mitosis, Parasitic Protozoans, Kinetoplasts, Trypanosomiasis, African, MESH: Trypanosomiasis, African, Nifurtimox, Lysosomes, Trypanosoma Brucei Gambiense, MESH: Lysosomes
وصف الملف: application/pdf
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المؤلفون: Julie Lorent, Maritza Jaramillo, Laia Masvidal, Tommy Alain, Ola Larsson, Visnu Chaparro, Bruno D. Fonseca, Tyson E. Graber, Léon C van Kempen, Maria Aguirre, Louis-Philippe Leroux
المساهمون: Institut Armand Frappier (INRS-IAF), Réseau International des Instituts Pasteur (RIIP)-Institut National de la Recherche Scientifique [Québec] (INRS), Karolinska Institutet [Stockholm], University of Ottawa [Ottawa], Jewish General Hospital, McGill University = Université McGill [Montréal, Canada], University Medical Center Groningen [Groningen] (UMCG), This work was supported by a Basil O'Connor starter scholar research award (5-FY14-78) and a research grant (6-FY16-151) from The March of Dimes Foundation to M.J. The Centre for Host-Parasite Interactions is supported by a Subvention de Regroupement Stratégique from the Fonds de Recherche du Québec en Nature et Technologies (FRQ-NT). M.J. is a recipient of a Bourse de Chercheur-Boursier Junior 1 from the Fonds de Recherche du Québec en Santé (FRQ-S) and a Subvention d'Établissement de Jeune Chercheur from the FRQ-S. V.C. is supported by a Ph.D. scholarship from the Fondation Universitaire Armand Frappier. Research in the laboratory of O.L. is supported by grants from the Swedish Research Council and the Wallenberg Academy Fellows program., We are grateful to Nahum Sonenberg for providing bone marrow from C57BL/6 s6k1−/− s6k2−/− mice (McGill University, Montreal, QC, Canada). We thank Medhi Jafarnejad (McGill University) for technical advice. We are thankful to Annie Sylvestre and Annik Lafrance for invaluable technical assistance. We acknowledge support from the Science for Life Laboratory, the National Genomics Infrastructure (NGI), and Uppmax for providing assistance in massive parallel sequencing and computational infrastructure.
المصدر: Infection and Immunity
Infection and Immunity, American Society for Microbiology, 2018, 86 (9), pp.e00244-18. ⟨10.1128/IAI.00244-18⟩
Infection and Immunity, 86(9):ARTN e00244-18. AMER SOC MICROBIOLOGYمصطلحات موضوعية: MESH: Signal Transduction, 0301 basic medicine, DIFFERENTIAL TRANSLATION, Protozoan Proteins, MESH: Toxoplasma/pathogenicity, RNA 5' Terminal Oligopyrimidine Sequence, MESH: Mice, Knockout, Mice, Poly(A)-binding protein, Protein biosynthesis, host-pathogen interactions, MESH: Animals, Cells, Cultured, Mice, Knockout, biology, IMMUNE-RESPONSES, TOR Serine-Threonine Kinases, translational control, Translation (biology), Cell biology, macrophages, Infectious Diseases, MESSENGER-RNA TRANSLATION, mTOR, PROTEIN-SYNTHESIS, MESH: Host-Parasite Interactions, [SDV.IMM]Life Sciences [q-bio]/Immunology, Toxoplasma, Signal Transduction, MESH: Cells, Cultured, Translational efficiency, Immunology, ENDOPLASMIC-RETICULUM, MESH: RNA 5' Terminal Oligopyrimidine Sequence, Toxoplasma gondii, Microbiology, DENDRITIC CELLS, Host-Parasite Interactions, POLY(A)-BINDING PROTEINS, Mitochondrial Proteins, 03 medical and health sciences, MESH: Protein Biosynthesis/genetics, MESH: Mice, Inbred C57BL, PARASITOPHOROUS VACUOLE MEMBRANE, parasitic diseases, Animals, MESH: Mice, Mechanistic target of rapamycin, Cellular Microbiology: Pathogen-Host Cell Molecular Interactions, 030102 biochemistry & molecular biology, Intracellular parasite, biology.organism_classification, MESH: Protozoan Proteins/immunology, Cytoplasm organization, Mice, Inbred C57BL, MESH: Mitochondrial Proteins/genetics, MAMMALIAN-TARGET, 030104 developmental biology, Protein Biosynthesis, MESH: TOR Serine-Threonine Kinases/genetics, biology.protein, INNATE IMMUNITY, MESH: Macrophages/parasitology, Parasitology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615ebb9a78a49ce9a9e41a7e1dacffad
https://doi.org/10.1128/iai.00244-18 -
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المؤلفون: Pfeiffer, Friedhelm, Bagyan, Irina, Alfaro-Espinoza, Gabriela, Zamora-Lagos, Maria-A, Marin-Sanguino, Alberto, Oesterhelt, Dieter, Kunte, Hans, Zamora-Lagos, Maria-A., Sun, Su, Habermann, Bianca
المساهمون: Bitop, Max-Planck-Institut für Biochemie (MPIB), Max-Planck-Gesellschaft, Scionics Computer Innovation GmbH, Scionics Computer Innovation
المصدر: Mitochondria
Mitochondria, 6 (4), pp.e00465, 2017, ⟨10.1002/mbo3.465⟩مصطلحات موضوعية: Mitochondrial protein localization, MESH: Databases, Protein, MESH: Protein Transport, MESH: Web Browser, genome annotation, sequence revision, MESH: Mitochondria, [SDV]Life Sciences [q-bio], In silico, Halomonas elongata, MESH: Mitochondrial Proteins, MESH: Algorithms, Prediction methods, frameshift, Mitochondrial targeting peptide, genome sequencing, MESH: Software, Protein localization algorithms, halophilic bacteria, MESH: Computational Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::bcb52bd0d3bfff902e7dde0fb2176f3d
https://hal.archives-ouvertes.fr/hal-02000495 -
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المؤلفون: B. Closs, Sylvie Bordes, Abdel Aouacheria, Célia Da Silva, Josselin Breugnot, Romain Jugé
المساهمون: SILAB, Institut des Sciences de l'Evolution de Montpellier (UMR ISEM), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Institut de recherche pour le développement [IRD] : UR226-Centre National de la Recherche Scientifique (CNRS), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-École Pratique des Hautes Études (EPHE)
المصدر: Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 6 (1), ⟨10.1038/srep35065⟩
Scientific Reports, 2016, 6 (1), ⟨10.1038/srep35065⟩مصطلحات موضوعية: Keratinocytes, 0301 basic medicine, MESH: Keratinocytes/cytology, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, Cell, MESH: Microtubule-Associated Proteins/genetics, Apoptosis, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], Mitochondrion, medicine.disease_cause, Mitochondrial Dynamics, MESH: Cell Survival/radiation effects, MESH: Mitochondria/genetics, MESH: Mitochondrial Proteins/genetics, GTP Phosphohydrolases, law.invention, 0302 clinical medicine, law, MESH: Microscopy, Confocal, MESH: Computational Biology/methods, MESH: Healthy Volunteers, [INFO.INFO-BT]Computer Science [cs]/Biotechnology, skin and connective tissue diseases, Cells, Cultured, chemistry.chemical_classification, education.field_of_study, Microscopy, Confocal, Multidisciplinary, integumentary system, MESH: Keratinocytes/radiation effects, Healthy Volunteers, Mitochondria, 3. Good health, Cell biology, medicine.anatomical_structure, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, [INFO.INFO-TI]Computer Science [cs]/Image Processing [eess.IV], MESH: Mitochondria/radiation effects, Microtubule-Associated Proteins, MESH: Cells, Cultured, Dynamins, Cell Survival, DNA damage, Population, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Article, Mitochondrial Proteins, MESH: GTP Phosphohydrolases/genetics, 03 medical and health sciences, Confocal microscopy, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], medicine, Humans, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], education, MESH: Mitochondrial Dynamics/radiation effects, MESH: DNA Damage, Reactive oxygen species, MESH: Humans, MESH: Apoptosis, Computational Biology, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, MESH: Reactive Oxygen Species/metabolism, MESH: Gene Knockdown Techniques, 030104 developmental biology, chemistry, Reactive Oxygen Species, Oxidative stress, DNA Damage
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المؤلفون: Vadim N. Gladyshev, Maxim V. Gerashchenko, Michel B. Toledano, Inge Seim, Jean Labarre, Alaattin Kaya
المساهمون: Division of Genetics, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Physiologie et Pathogénicité des Stress (PEPS), Département Biologie des Génomes (DBG), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Biologie et de Technologies de Saclay (IBITECS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Stress Oxydatif et Cancer (SOC), Département Biologie Cellulaire (BioCell), Physiologie et Pathogénicité des Stress ( PEPS ), Département Biologie des Génomes ( DBG ), Institut de Biologie Intégrative de la Cellule ( I2BC ), Université Paris-Sud - Paris 11 ( UP11 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Centre National de la Recherche Scientifique ( CNRS ) -Université Paris-Sud - Paris 11 ( UP11 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Centre National de la Recherche Scientifique ( CNRS ) -Institut de Biologie Intégrative de la Cellule ( I2BC ), Université Paris-Sud - Paris 11 ( UP11 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Centre National de la Recherche Scientifique ( CNRS ) -Université Paris-Sud - Paris 11 ( UP11 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Centre National de la Recherche Scientifique ( CNRS ), Institut de Biologie et de Technologies de Saclay ( IBITECS ), Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ), Laboratoire Stress Oxydants et Cancer ( LSOC ), Département Biologie Cellulaire ( BioCell )
المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2015, 112 (34), pp.10685-90. ⟨10.1073/pnas.1505315112⟩
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (34), pp.10685-90. ⟨10.1073/pnas.1505315112⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2015, 112 (34), pp.10685-90. 〈10.1073/pnas.1505315112〉مصطلحات موضوعية: MESH : Chromosomes, Fungal, [SDV]Life Sciences [q-bio], MESH : Peroxidases, MESH : Saccharomyces cerevisiae, Gene Dosage, MESH : Reactive Oxygen Species, Antimycin A, MESH : Gene Deletion, MESH: Oligomycins, Mitochondrion, MESH: Heat-Shock Proteins, medicine.disease_cause, MESH : Aneuploidy, MESH : Antimycin A, MESH: Gene Dosage, MESH : Rotenone, MESH: Peroxidases, thiol peroxidase, 0302 clinical medicine, MESH: Saccharomyces cerevisiae Proteins, oxidative stress, MESH : Gene Dosage, Oxidoreductases Acting on Sulfur Group Donors, MESH : Oligomycins, MESH : Adaptation, Physiological, Heat-Shock Proteins, MESH : Electron Transport, 2. Zero hunger, chemistry.chemical_classification, 0303 health sciences, Multidisciplinary, Dosage compensation, biology, Cytochrome c peroxidase, MESH: Mitochondrial Proteins, MESH: Reactive Oxygen Species, Biological Sciences, MESH: Saccharomyces cerevisiae, MESH: Chromosomes, Fungal, Adaptation, Physiological, Biochemistry, Peroxidases, MESH: Hydrogen Peroxide, MESH: Membrane Proteins, MESH: Oxidoreductases Acting on Sulfur Group Donors, Chromosome Deletion, Chromosomes, Fungal, Peroxidase, Saccharomyces cerevisiae Proteins, Cellular respiration, MESH: Chromosome Deletion, Saccharomyces cerevisiae, Genes, Fungal, MESH : Saccharomyces cerevisiae Proteins, Electron Transport, Mitochondrial Proteins, 03 medical and health sciences, Rotenone, medicine, MESH: Aneuploidy, MESH : Cytochrome-c Peroxidase, MESH: Cytochrome-c Peroxidase, MESH: Electron Transport, MESH : Mitochondrial Proteins, 030304 developmental biology, Reactive oxygen species, [ SDV ] Life Sciences [q-bio], Membrane Proteins, Hydrogen Peroxide, MESH : Heat-Shock Proteins, Cytochrome-c Peroxidase, biology.organism_classification, MESH : Chromosome Deletion, Aneuploidy, MESH: Adaptation, Physiological, MESH : Oxidoreductases Acting on Sulfur Group Donors, chemistry, MESH : Membrane Proteins, MESH: Gene Deletion, biology.protein, Oligomycins, MESH : Genes, Fungal, MESH : Hydrogen Peroxide, MESH: Rotenone, MESH: Antimycin A, MESH: Genes, Fungal, Reactive Oxygen Species, 030217 neurology & neurosurgery, Oxidative stress, respiration, Gene Deletion
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d62c216f758d47b792b39b62ce037a0
https://europepmc.org/articles/PMC4553801/
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