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المؤلفون: Margaux Sala, Nathalie Allain, Mélanie Moreau, Arnaud Jabouille, Elodie Henriet, Aya Abou-Hammoud, Arnaud Uguen, Sylvaine Di-Tommaso, Cyril Dourthe, Anne-Aurélie Raymond, Jean-William Dupuy, Emilie Gerard, Nathalie Dugot-Senant, Benoit Rousseau, Jean-Phillipe Merlio, Anne Pham-Ledart, Béatrice Vergier, Sophie Tartare-Deckert, Violaine Moreau, Frédéric Saltel
المساهمون: BoRdeaux Institute in onCology (Inserm U1312 - BRIC), Université de Bordeaux (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM), Johns Hopkins University (JHU), Microbiologie Fondamentale et Pathogénicité (MFP), Université Bordeaux Segalen - Bordeaux 2-Centre National de la Recherche Scientifique (CNRS), Hôpital Morvan - CHRU de Brest (CHU - BREST ), TBM-Core [Bordeaux] (CNRS UMS 3427 - INSERM US 005), Université de Bordeaux (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université de Bordeaux (UB), CHU Bordeaux [Bordeaux], Bordeaux Research In Translational Oncology [Bordeaux] (BaRITOn), Université de Bordeaux (UB)-CHU Bordeaux [Bordeaux]-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), TARTARE-DECKERT, Sophie
المصدر: Oncogene
Oncogene, 2022, 41 (18), pp.2571-2586. ⟨10.1038/s41388-022-02266-1⟩مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, MESH: Proto-Oncogene Proteins B-raf, Cancer Research, MESH: Cell Line, Tumor, MESH: Humans, MESH: Melanoma, [SDV]Life Sciences [q-bio], MESH: Phenotype, MESH: Drug Resistance, Neoplasm, [SDV] Life Sciences [q-bio], Discoidin Domain Receptor 2, Phenotype, Drug Resistance, Neoplasm, Cell Line, Tumor, MESH: Cell Proliferation, MESH: Discoidin Domain Receptor 2, Genetics, Humans, MESH: Protein Kinase Inhibitors, Melanoma, Protein Kinase Inhibitors, Molecular Biology, Cell Proliferation
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المؤلفون: Jérémy Dufloo, Cyril Planchais, Stéphane Frémont, Valérie Lorin, Florence Guivel-Benhassine, Karl Stefic, Nicoletta Casartelli, Arnaud Echard, Philippe Roingeard, Hugo Mouquet, Olivier Schwartz, Timothée Bruel
المساهمون: Virus et Immunité - Virus and immunity (CNRS-UMR3569), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), École Doctorale Bio Sorbonne Paris Cité [Paris] (ED562 - BioSPC), Université Sorbonne Paris Cité (USPC)-Université Paris Cité (UPCité), Immunologie humorale - Humoral Immunology, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Trafic membranaire et Division cellulaire - Membrane Traffic and Cell Division, Hôpital Bretonneau, Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Plateforme IBISA de Microscopie Electronique [CHRU de Tours] (UNIV Tours), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours)-Université de Tours (UT), Vaccine Research Institute [Créteil, France] (VRI), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), O.S. is funded by Institut Pasteur, Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS), Sidaction, the Vaccine Research Institute (ANR-10-LABX-77), Labex IBEID (ANR-10-LABX-62-IBEID), 'TIMTAMDEN' ANR-14-CE14-0029, 'CHIKV-Viro-Immuno' ANR-14-CE14-0015-01, and the Gilead HIV cure program. J.D. is funded by a Ph.D grant from the French Ministry of Higher Education and Research. H.M. is funded by the Institut Pasteur, the Milieu Intérieur Program (ANR-10-LABX-69-01), INSERM, ANRS, and Gilead HIV cure program. C.P. was supported by an ANRS fellowship. A.E. and S.F. are funded by Institut Pasteur, CNRS, and ANRS (ANRS-21020 AP2020-2). P.R. is funded by INSERM, Université de Tours and ANRS., ANR-10-LABX-0077,VRI,Initiative for the creation of a Vaccine Research Institute(2010), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-14-CE14-0029,TIMTAMDEN,Rôle des récepteurs TIM et TAM dans l'infection des cellules cibles par le virus de la dengue(2014), ANR-14-CE14-0015,CHIKV-Viro-Immuno,Multiplication et Relation avec l'hôte du virus Chikungunya(2014), ANR-10-LABX-0069,MILIEU INTERIEUR,GENETIC & ENVIRONMENTAL CONTROL OF IMMUNE PHENOTYPE VARIANCE: ESTABLISHING A PATH TOWARDS PERSONALIZED MEDICINE(2010), Virus et Immunité - Virus and immunity, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Vaccine Research Institute (VRI), Institut Pasteur, Agence Nationale de la Recherche (France), Ministére de l'Education Nationale de la Recherche et de la Technologie (France), Université de Tours
المصدر: Nature Communications
Nature Communications, 2022, 13 (1), pp.630. ⟨10.1038/s41467-022-28307-7⟩
Nature Communications, Nature Publishing Group, 2022, 13 (1), pp.630. ⟨10.1038/s41467-022-28307-7⟩
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)مصطلحات موضوعية: MESH: Epitopes, T-Lymphocytes, Science, viruses, General Physics and Astronomy, HIV Infections, MESH: Host Microbial Interactions, HIV Antibodies, General Biochemistry, Genetics and Molecular Biology, Cell Line, MESH: Antibodies, Neutralizing, MESH: HIV-1, Epitopes, MESH: Antibody-Dependent Cell Cytotoxicity, Humans, MESH: Broadly Neutralizing Antibodies, Multidisciplinary, MESH: Humans, Host Microbial Interactions, MESH: HIV Antibodies, Antibody-Dependent Cell Cytotoxicity, Virion, env Gene Products, Human Immunodeficiency Virus, virus diseases, General Chemistry, MESH: HIV Infections, Antibodies, Neutralizing, MESH: Cell Line, MESH: T-Lymphocytes, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, HIV-1, MESH: Virion, MESH: env Gene Products, Human Immunodeficiency Virus, Broadly Neutralizing Antibodies
وصف الملف: application/pdf
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المؤلفون: de Krijger, Inge, Föhr, Bastian, Pérez, Santiago Hernández, Vincendeau, Estelle, Serrat, Judit, Thouin, Alexander Marc, Susvirkar, Vivek, Lescale, Chloé, Paniagua, Inés, Hoekman, Liesbeth, Kaur, Simranjeet, Altelaar, Maarten, Deriano, Ludovic, Faesen, Alex C, Jacobs, Jacqueline J L, Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
المساهمون: Netherlands Cancer Institute (NKI), Antoni van Leeuwenhoek Hospital, Max Planck Institute for Biophysical Chemistry (MPI-BPC), Max-Planck-Gesellschaft, Université Paris Diderot, Sorbonne Paris Cité, Paris, France, Université Paris Diderot - Paris 7 (UPD7), Intégrité du génome, immunité et cancer - Genome integrity, Immunity and Cancer, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Physiopathologie du système immunitaire (Inserm U1223), Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University [Utrecht], This work was supported by project grant 10999/2017-1 from the Dutch Cancer Society (KWF) to J.J.L.J., by the Institut Pasteur to L.D., by the Institut National Du Cancer (INCA_13852) to L.D., by the Ligue Nationale Contre le Cancer (Equipe labellisée 2019) to L.D. The Proteomics Facility of the Netherlands Cancer Institute was supported by the X-omics Initiative, partially funded by the Dutch Research Council (NWO)(project 184.034.019). E.V. received funding from Université de Paris, Sorbonne Paris Cité. A.C.F. is grateful for generous core funding by the Max Planck Society., Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Université Sorbonne Paris Cité (USPC), Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics, Institut Pasteur [Paris], Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur [Paris], Lescale, Chloé
المصدر: Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.5421. ⟨10.1038/s41467-021-25724-y⟩
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, 12(1). Nature Publishing Group
Nature Communications, 2021, 12 (1), pp.5421. ⟨10.1038/s41467-021-25724-y⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-25724-y⟩مصطلحات موضوعية: DNA Repair, Chemistry(all), ATPase, MESH: DNA Breaks, Double-Stranded, Gene Expression, General Physics and Astronomy, Cell Cycle Proteins, [SDV.GEN] Life Sciences [q-bio]/Genetics, [SDV.BBM.BM] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Biochemistry, Piperazines, MESH: Recombinant Proteins, Mice, chemistry.chemical_compound, 0302 clinical medicine, DNA Breaks, Double-Stranded, MESH: Animals, 0303 health sciences, Multidisciplinary, biology, Chemistry, MESH: Protein Multimerization, DNA damage and repair, MESH: DNA, Recombinant Proteins, 3. Good health, Cell biology, DNA-Binding Proteins, MESH: ATPases Associated with Diverse Cellular Activities, MESH: HEK293 Cells, Mad2 Proteins, MESH: Phthalazines, MESH: Mad2 Proteins, Protein Binding, MESH: Cell Line, Tumor, MESH: Gene Expression, DNA repair, Science, Physics and Astronomy(all), Article, Chromosomes, General Biochemistry, Genetics and Molecular Biology, Cell Line, 03 medical and health sciences, MESH: Cell Cycle Proteins, Cell Line, Tumor, Animals, Humans, MESH: Protein Binding, Protein Interaction Domains and Motifs, MESH: Mice, 030304 developmental biology, MESH: Protein Interaction Domains and Motifs, [SDV.GEN]Life Sciences [q-bio]/Genetics, Binding Sites, MESH: Humans, TRIP13, Biochemistry, Genetics and Molecular Biology(all), [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, DNA, General Chemistry, DNA Repair Pathway, Fibroblasts, MESH: Cell Line, HEK293 Cells, MESH: Binding Sites, MESH: Cisplatin, MESH: Fibroblasts, MESH: HeLa Cells, biology.protein, ATPases Associated with Diverse Cellular Activities, Phthalazines, Cisplatin, Protein Multimerization, 030217 neurology & neurosurgery, Function (biology), MESH: DNA-Binding Proteins, HeLa Cells, Genetics and Molecular Biology(all)
وصف الملف: application/pdf
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المؤلفون: Tobias Sahr, Pedro Escoll, Christophe Rusniok, Sheryl Bui, Gérard Pehau-Arnaudet, Gregory Lavieu, Carmen Buchrieser
المساهمون: Biologie des Bactéries intracellulaires - Biology of Intracellular Bacteria, Université Paris Cité (UPCité)-Microbiologie Intégrative et Moléculaire (UMR6047), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Paris Cité (UPCité), Matière et Systèmes Complexes (MSC), Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Plateforme BioImagerie Ultrastructurale – Ultrastructural BioImaging Platform (UTechS UBI), Institut Pasteur [Paris] (IP), Work in the C.B. laboratory was financed by the grant n° ANR-20-CE15-0021-01-BIOEV, the Institut Pasteur, the Fondation pour la Recherche Médicale (FRM) grant N° EQU201903007847 and the grant n°ANR-10-LABX-62-IBEID. For electron microscopy experiments M. Nilges and the Equipex CACSICE (n° ANR-11-EQPX-0008) provided funding for the Falcon II direct detector. G.L. lab is funded by ANR-20-CE15-0021-02, ANR-19-CE18-0020-03, and ANR-18-IDEX-0001, IdEx Université de Paris. S.B. is a recipient of a PhD fellowship from PSL University. The funders, other than the authors, did not play any role in the study or in the preparation of the article or decision to publish., We thank Monica Rolando for critically reading of the manuscript and helpful discussions and Nathalie Aulner and Anne Danckaert, Photonic BioImaging (PBI) UTechS for support., T.S., P.E., S.B., and G.L. performed the experiments, C.R. performed the bioinformatics analyses, GPA performed the electron and cryoTEM experiments, T.S., P.E., and C.B. designed the experiments, T.S. and C.B. wrote the article, C.B. supervised the work and acquired funds., ANR-20-CE15-0021,BioEV,Biogenèse, trafic et rôles des vésicules extracllulaires de Legionella pneumophila au cours de l'infection(2020), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-11-EQPX-0008,CACSICE,Centre d'analyse de systèmes complexes dans les environnements complexes(2011), ANR-19-CE18-0020,EXCELLDISC,Vésicules Extracellulaires et thérapie du disque intervertébral(2019), ANR-18-IDEX-0001,Université de Paris,Université de Paris(2018)
المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Nature Communications
Nature Communications, 2022, 13 (1), pp.762. ⟨10.1038/s41467-022-28454-x⟩مصطلحات موضوعية: MESH: Signal Transduction, Science, General Physics and Astronomy, MESH: Legionnaires' Disease, MESH: DEAD Box Protein 58, General Biochemistry, Genetics and Molecular Biology, Cell Line, Legionella pneumophila, MESH: Interleukin-1 Receptor-Associated Kinases, Extracellular Vesicles, Bacterial Proteins, Humans, Receptors, Immunologic, MESH: Extracellular Vesicles, MESH: Bacterial Proteins, MESH: Receptors, Immunologic, MESH: Humans, Multidisciplinary, MESH: Host-Pathogen Interactions, Eukaryota, General Chemistry, bacterial infections and mycoses, MESH: Legionella pneumophila, Immunity, Innate, MESH: Cell Line, respiratory tract diseases, MicroRNAs, MESH: Eukaryota, Interleukin-1 Receptor-Associated Kinases, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Host-Pathogen Interactions, DEAD Box Protein 58, bacteria, MESH: Immunity, Innate, Legionnaires' Disease, MESH: MicroRNAs, Signal Transduction
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المؤلفون: Jean-François Eléouët, Monika Bajorek, Luis Checa Ruano, Marie Galloux, Jenna Fix, Charles-Adrien Richard, Hortense Decool, Olivier Sperandio, Irina Gutsche, Benjamin Bardiaux
المساهمون: Virologie et Immunologie Moléculaires (VIM (UR 0892)), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Bioinformatique structurale - Structural Bioinformatics, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Molécules Thérapeutiques in silico (MTI), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut de biologie structurale (IBS - UMR 5075), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), ANR-19-CE11-0017, Agence Nationale de la Recherche, ANR, This work was carried out with the financial support of the French Agence Nationale de la Recherche, specific program ANR DecRisP, grant no. ANR-19-CE11-0017. We declare that we have no conflicts of interest with the contents of this article., ANR-19-CE11-0017,DecRisP,Décrypter les synthèses d'ARN par les pneumovirus(2019)
المصدر: J Virol
Journal of Virology
Journal of Virology, 2022, 96 (2), pp.e0090921. ⟨10.1128/JVI.00909-21⟩مصطلحات موضوعية: Models, Molecular, viruses, MESH: Cricetinae, Virus Replication, chemistry.chemical_compound, Protein-protein interaction, Transcription (biology), MESH: Metapneumovirus, RNA polymerase, Cricetinae, Structural modeling, MESH: Animals, Polymerase, Inclusion Bodies, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], HMPV, Nucleocapsid Proteins, Phosphoprotein, MESH: RNA, Viral, MESH: RNA-Dependent RNA Polymerase, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, RNA, Viral, MESH: Models, Molecular, Protein Binding, MESH: Mutation, Immunology, Biology, MESH: Phosphoproteins, Microbiology, Cell Line, Human metapneumovirus, Virology, MESH: Protein Binding, Animals, Protein Interaction Domains and Motifs, Nucleoprotein, MESH: Protein Interaction Domains and Motifs, Binding Sites, Structure and Assembly, MESH: Virus Replication, RNA, MESH: Nucleocapsid Proteins, biology.organism_classification, Phosphoproteins, RNA-Dependent RNA Polymerase, MESH: Inclusion Bodies, MESH: Cell Line, MESH: Binding Sites, Viral replication, chemistry, Insect Science, Mutation, biology.protein, Metapneumovirus
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7efcc80720167008066e4d77c332fd
https://europepmc.org/articles/PMC8791268/ -
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المؤلفون: Cherif, Chaïma, Nguyen, Dang Tan, Paris, Clément, Le, Thi Khanh, Sefiane, Thibaud, Carbuccia, Nadine, Finetti, Pascal, Chaffanet, Max, Kaoutari, Abdessamad El, Vernerey, Julien, Fazli, Ladan, Gleave, Martin, Manai, Mohamed, Barthélémy, Philippe, Birnbaum, Daniel, Bertucci, François, Taïeb, David, Rocchi, Palma
المساهمون: Centre de Recherche en Cancérologie de Marseille (CRCM), Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), University of British Columbia (UBC), University of Tunis El Manar, Acides Nucléiques : Régulations Naturelle et Artificielle (ARNA), Université de Bordeaux (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Rocchi, Palma
المصدر: Oncogene
Oncogene, 2022, 41 (1), pp.125-137. ⟨10.1038/s41388-021-02039-2⟩مصطلحات موضوعية: Male, congenital, hereditary, and neonatal diseases and abnormalities, endocrine system, MESH: Cell Line, Tumor, MESH: Humans, endocrine system diseases, MESH: Genomics, [SDV]Life Sciences [q-bio], Genomics, Hormone receptors, urologic and male genital diseases, Article, MESH: Male, MESH: Proto-Oncogene Proteins, [SDV] Life Sciences [q-bio], Prostatic Neoplasms, Castration-Resistant, Cell Line, Tumor, Proto-Oncogene Proteins, MESH: Cell Proliferation, MESH: Prostatic Neoplasms, Castration-Resistant, Animals, Humans, MESH: Animals, Cancer genetics, Cell Proliferation
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المؤلفون: Elia Bozzato, Nikolaos Tsakiris, Adrien Paquot, Giulio G. Muccioli, Chiara Bastiancich, Véronique Préat
المساهمون: Institut de neurophysiopathologie (INP), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)
المصدر: International Journal of Pharmaceutics
International Journal of Pharmaceutics, 2022, 628, pp.122341. ⟨10.1016/j.ijpharm.2022.122341⟩مصطلحات موضوعية: MESH: Hydrogels, Local delivery, MESH: Cell Line, Tumor, Curcumin, [SDV]Life Sciences [q-bio], Pharmaceutical Science, [SDV.CAN]Life Sciences [q-bio]/Cancer, Cell Line, MESH: Glioma, MESH: Curcumin, Cell Line, Tumor, Glioma stem cells, Humans, MESH: Humans, Tumor, Gemcitabine, Glioblastoma, Hydrogel, Salinomycin, Nanomedicine, Hydrogels, Lipids, Neoplastic Stem Cells, Brain Neoplasms, Glioma, MESH: Glioblastoma, MESH: Lipids, MESH: Neoplastic Stem Cells, MESH: Nanomedicine, MESH: Brain Neoplasms
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المؤلفون: Benoît Arragain, Quentin Durieux Trouilleton, Florence Baudin, Jan Provaznik, Nayara Azevedo, Stephen Cusack, Guy Schoehn, Hélène Malet
المساهمون: Groupe Imagerie microscopique d'assemblages complexes / Microscopic Imaging of complex Assemblies group (IBS MICA), Institut de biologie structurale (IBS - UMR 5075), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), EMBL Heidelberg, European Molecular Biology Laboratory [Grenoble] (EMBL), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), EMBL Eukaryotic Expression facility, IBS Electron Miroscopy Platform, EMBL GeneCore, Institut Universitaire de France, ANR-19-CE11-0024,HiPathBunya,Caractérisation des machineries de réplication de Bunyavirus hautement pathogènes par une approche de biologie structurale intégrée(2019), European Project: FDT202012010396
المصدر: Nature Communications
Nature Communications, 2022, 13 (1), pp.902. ⟨10.1038/s41467-022-28428-z⟩مصطلحات موضوعية: Transcription, Genetic, Protein Conformation, General Physics and Astronomy, Genome, Viral, Virus Replication, General Biochemistry, Genetics and Molecular Biology, Cell Line, MESH: Protein Conformation, La Crosse virus, MESH: Sequence Analysis, RNA, Humans, Multidisciplinary, MESH: Humans, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Sequence Analysis, RNA, MESH: Transcription, Genetic, Cryoelectron Microscopy, MESH: Virus Replication, General Chemistry, RNA-Dependent RNA Polymerase, MESH: Cell Line, HEK293 Cells, MESH: La Crosse virus, MESH: RNA, Viral, MESH: RNA-Dependent RNA Polymerase, MESH: HEK293 Cells, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, RNA, Viral, MESH: Cryoelectron Microscopy, MESH: Genome, Viral
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المؤلفون: Gavin R. Screaton, Pablo Guardado-Calvo, Félix A. Rey, Xinghong Dai, Danyang Gong, Patrick England, Alexander Rouvinski, Marie-Christine Vaney, Ahmed Haouz, Z. Hong Zhou, Wanwisa Dejnirattisai, Stéphane Duquerroy, Ren Sun, Arvind Sharma, Xiaokang Zhang, Wiyada Wongwiwat, Juthathip Mongkolsapaya
المساهمون: Virologie Structurale - Structural Virology, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université Paris Cité (UPCité), Institut Pasteur de Shanghai, Académie des Sciences de Chine - Chinese Academy of Sciences (IPS-CAS), Réseau International des Instituts Pasteur (RIIP), University of Oxford, University of California [Los Angeles] (UCLA), University of California (UC), Université Paris-Saclay, Centre de Ressources et de Recherche Technologique - Center for Technological Resources and Research (C2RT), Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité), Cristallographie (Plateforme) - Crystallography (Platform), Siriraj Hospital, Mahidol University, Mahidol University [Bangkok], This project was supported by a Wellcome Trust collaborative grant (UNS22082 to G.R.S., J.M., and F.A.R.), by the National Institute for Health Research Biomedical Research Centre Funding Scheme (to G.R.S.), and by grants from the National Institutes of Health (DE028583, AI094386, and DE025567 to Z.H.Z. and R.S.)., We thank Fabrice Agou and the staff of the Chemogenomic and Biological Screening Platform for access to the MALS equipment as well as the staff of the Crytallography core facility at the Institut Pasteur for robot-driven crystallization screens. We acknowledge the use of synchrotron beam lines PX1 and PX2 at SOLEIL (St Aubin, France), ID29 and ID23-1 at ESRF (Grenoble, France) and X06SA at SLS (Villigen, Switzerland), and we thank their staff for assistance. We also acknowledge the use of the resources at the Electron Imaging Center for Nanomachines, supported in part by 1S10RR23057, 1S10OD018111, 1U24GM116792 and NSF DBI-1338135 and DMR-1548924 at UCLA. G.R.S. is supported as a Wellcome Trust Senior Investigator (095541/A/11/Z). F.A.R. is supported by Institut Pasteur and the CNRS.
المصدر: Cell
Cell, 2021, 184 (25), pp.6052-6066.e18. ⟨10.1016/j.cell.2021.11.010⟩
'Cell ', vol: 184, pages: 6052-6066 (2021)مصطلحات موضوعية: medicine.drug_class, [SDV]Life Sciences [q-bio], MESH: Vero Cells, MESH: Zika Virus, MESH: Dengue, Biology, Dengue virus, Monoclonal antibody, medicine.disease_cause, MESH: Dengue Virus, complex mixtures, General Biochemistry, Genetics and Molecular Biology, Epitope, Neutralization, Zika virus, MESH: Antibodies, Monoclonal, MESH: Antibodies, Neutralizing, MESH: Drosophila melanogaster, MESH: Cross Reactions, MESH: Protein Conformation, MESH: Zika Virus Infection, MESH: Chlorocebus aethiops, medicine, MESH: Protein Binding, MESH: Animals, X-ray crystallography, MESH: Humans, Flaviviruses, broadly neutralizing antibodies, biology.organism_classification, Virology, MESH: Cell Line, Flavivirus, MESH: HEK293 Cells, MESH: Viral Envelope Proteins, biology.protein, vaccine design, cryo-EM, Paratope, lipids (amino acids, peptides, and proteins), Antibody, MESH: Antibodies, Viral
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed324443d134d4421f6eaae4a0c0717
https://hal-pasteur.archives-ouvertes.fr/pasteur-03524447/document -
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المؤلفون: Wei-Liang Liu, Chia-Wei Hsu, Shih-Peng Chan, Pei-Shi Yen, Matthew P. Su, Jian-Chiuan Li, Hsing-Han Li, Lie Cheng, Cheng-Kang Tang, Shih-Hsun Ko, Huai-Kuang Tsai, Zing Tsung-Yeh Tsai, Omar S. Akbari, Anna-Bella Failloux, Chun-Hong Chen
المساهمون: National Health Research Institutes [Taiwan] (NHRI), National Taiwan University [Taiwan] (NTU), Arbovirus et Insectes Vecteurs - Arboviruses and Insect Vectors, Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité), Nagoya University, Academia Sinica, University of California [San Diego] (UC San Diego), University of California (UC), This study also was supported by the National Health Research Institutes (NHRI), Taiwan (Grant No. NHRI-MR-110-GP-12) and Ministry of Health and Welfare (Grant No. MOHW103-TDU-B-212-000005) awarded to Chun-Hong Chen.
المصدر: Scientific Reports
Scientific reports, vol 11, iss 1
Scientific Reports, 2021, 11 (1), pp.23865. ⟨10.1038/s41598-021-03229-4⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)مصطلحات موضوعية: Mosquito Control, [SDV]Life Sciences [q-bio], viruses, MESH: Cricetinae, Transposases, MESH: Dengue, Pathogenesis, MESH: Dengue Virus, Dengue, MESH: Cricetulus, Aedes, Cricetinae, MESH: RNA, Small Interfering, 2.2 Factors relating to the physical environment, MESH: Animals, Aetiology, MESH: Mosquito Control, Multidisciplinary, virus diseases, MESH: Aedes, Viral Load, Infectious Diseases, Medicine, MESH: Mosquito Vectors, MESH: Viral Load, Infection, Biotechnology, Science, Genetically Modified, Mosquito Vectors, Small Interfering, Serogroup, Article, Cell Line, MESH: Animals, Genetically Modified, Vaccine Related, Cricetulus, Rare Diseases, Biodefense, Genetics, Animals, Prevention, MESH: Serogroup, Fibroblasts, Dengue Virus, MESH: Cell Line, Vector-Borne Diseases, Emerging Infectious Diseases, Good Health and Well Being, MESH: Fibroblasts, RNAi, MESH: Transposases, RNA
وصف الملف: application/pdf