نتائج البحث - "MESH : Conserved Sequence"

1

Analysis of diverse eukaryotes suggests the existence of an ancestral mitochondrial apparatus derived from the bacterial type II secretion system

المساهمون: Dpt of Parasitology [Prague], Charles University [Prague] (CU), Ostravská univerzita / University of Ostrava, University of Birmingham [Birmingham], University of Kent [Canterbury], Czech Academy of Sciences [Prague] (CAS), Faculty of Medicine [Brno] (MED / MUNI), Masaryk University [Brno] (MUNI), Dalhousie University [Halifax], Center for Cellular Imaging and Nanoanalytics, University of Basel (Unibas), Biochimie des Interactions Macromoléculaires / Biochemistry of Macromolecular Interactions, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Université de Montréal (UdeM), This work was supported by Czech Science Foundation grants 13-29423S to P.D. and 18-18699S to M.E., and the KONTAKT II grant LH15253 provided by Ministry of Education, Youth and Sports of CR (MEYS) to P.D., This work was also supported by MEYS within the National Sustainability Program II (Project BIOCEV-FAR, LQ1604) the project BIOCEV (CZ.1.05/1.1.00/02.0109), and the project 'Centre for research of pathogenicity and virulence of parasites' (No. CZ.02.1.01/0.0/0.0/16_019/0000759) funded by European Regional Development Fund (ERDF) and MEYS and by Moore-Simons Project on the Origin of the Eukaryotic Cell to P.D. https://doi.org/10.37807/GBMF9738, The work in the OF laboratory was funded by the ANR-14-CE09-0004 grant. J.P. was supported by a grant from the Gordon and Betty Moore Foundation to ADT. This work was supported by The Ministry of Education, Youth and Sports from the Large Infrastructures for Research, Experimental Development and Innovations project 'IT4Innovations National Supercomputing Center – LM2015070'., ANR-14-CE09-0004,FiberSpace,Pili de type IV et pseudopili: structure, dynamique, assemblage et fonction moléculaire(2014), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2947. ⟨10.1038/s41467-021-23046-7⟩
Nature Communications, 2021, 12 (1), pp.2947. ⟨10.1038/s41467-021-23046-7⟩
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)

مصطلحات موضوعية: Models, Molecular, Protein family, MESH: Mitochondria, MESH: Sequence Homology, Amino Acid, Science, [SDV]Life Sciences [q-bio], Protozoan Proteins, MESH: Amino Acid Sequence, Mitochondrion, Biology, MESH: Naegleria, Models, Biological, Article, Evolutionary genetics, Evolution, Molecular, Mitochondrial Proteins, Gram-Negative Bacteria, Type II Secretion Systems, parasitic diseases, MESH: Gram-Negative Bacteria, Peroxisomes, Secretion, Amino Acid Sequence, MESH: Phylogeny, MESH: Protozoan Proteins, Conserved Sequence, Phylogeny, MESH: Evolution, Molecular, Sequence (medicine), Genetics, MESH: Type II Secretion Systems, Protein translocation, MESH: Conserved Sequence, Sequence Homology, Amino Acid, Phylogenetic tree, Type II secretion system, fungi, MESH: Models, Biological, Eukaryota, MESH: Mitochondrial Proteins, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Naegleria, Peroxisome, MESH: Peroxisomes, Mitochondria, MESH: Eukaryota, Bacterial outer membrane, MESH: Models, Molecular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b800b20644833bfb7b700b78814074d6
https://hal-pasteur.archives-ouvertes.fr/pasteur-03247185

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2

Self-association of MreC as a regulatory signal in bacterial cell wall elongation

المؤلفون: Carlos Contreras-Martel, Leandro F. Estrozi, Daniel M. Trindade, Mayara M. Miyachiro, Fernanda Rodrigues-Costa, Ina Attrée, Guy Schoehn, Caíque C. Malospirito, Alexandre Martins, Viviana Job, Andréa Dessen, Lionel Imbert, Manon Janet-Maitre

المساهمون: Institut de biologie structurale (IBS - UMR 5075), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), Groupe Pathogenèse Bactérienne et Réponses Cellulaires / Bacterial Pathogenesis and Cellular Responses Group (IBS-PBRC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Brazilian Biosciences National Laboratory (LNBio), National Center for Research in Energy and Materials, Groupe de RMN biomoléculaire (IBS-NMR), ANR-18-CE11-0019,PSEUDO-WALL,Architecture et fonction de complexes de la biosynthèse de la paroi cellulaire de Pseudomonas aeruginosa(2018)

المصدر: Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-22957-9⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2987. ⟨10.1038/s41467-021-22957-9⟩
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications, 2021, 12 (1), pp.2987. ⟨10.1038/s41467-021-22957-9⟩

مصطلحات موضوعية: 0301 basic medicine, Science, General Physics and Astronomy, MESH: Amino Acid Sequence, MreB, General Biochemistry, Genetics and Molecular Biology, Bacterial cell structure, Article, MESH: Recombinant Proteins, 03 medical and health sciences, 0302 clinical medicine, Protein structure, MESH: Cell Wall, Phylogenetics, Cryoelectron microscopy, MESH: Phylogeny, MESH: Bacterial Proteins, MESH: Mutagenesis, X-ray crystallography, chemistry.chemical_classification, MESH: Protein Conformation, alpha-Helical, Bacterial structural biology, Multidisciplinary, MESH: Conserved Sequence, biology, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Chemistry, MESH: Protein Multimerization, Mutagenesis, General Chemistry, biology.organism_classification, MESH: Crystallography, X-Ray, Cell biology, 030104 developmental biology, Enzyme, MESH: Pseudomonas aeruginosa, MESH: Protein Domains, MESH: Protein Conformation, beta-Strand, MESH: Cryoelectron Microscopy, Elongation, 030217 neurology & neurosurgery, Bacteria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10cfc0966af3321d6631a2a3d7bddc79
http://europepmc.org/articles/PMC8137920

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3

The steroid derivative 6-aminocholestanol inhibits the DEAD-box helicase eIF4A (LieIF4A) from the Trypanosomatid parasite Leishmania by perturbing the RNA and ATP binding sites

المؤلفون: N. Kyle Tanner, Mourad Barhoumi, Emna Harigua-Souiai, Arnaud Blondel, Josette Banroques, Yosser Zina Abdelkrim, Ikram Guizani

المساهمون: Expression Génétique Microbienne (EGM (UMR_8261 / FRE_3630)), Institut de biologie physico-chimique (IBPC (FR_550)), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP), Faculté des Sciences de Bizerte [Université de Carthage], Université de Carthage - University of Carthage, Bioinformatique structurale - Structural Bioinformatics, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), This work was supported by the Centre National de la Recherche Scientifique, France, by the HelicaRN [2010 BLAN 1503 01] and HeliDEAD grants [ANR-13-BSV8-0009-01] from the Agence Nationale de la Recherche, France, and by the Initiative d'Excellence program from the French State [Grant DYNAMO, ANR-11-LABX-0011-01] to NKT. This work received financial support from the Pasteur Institute Transversal Research Program (grant PTR426), France, and partially from the Ministry of Higher Education and Research in Tunisia (LR11IPT04 & LR16IPT04) to IG. EHS received support from the UNESCO-L'Oréal, 'For Women in Science,' international fellowship and the Institut Pasteur International Network (Calmette and Yersin programme)., We thank Patrick Linder, Centre Médical Universitaire, Geneva, Switzerland, for the eIF4AIMus clone. The 6-aminocholestanol was a gift from Dr. Leila el Kihel, Centre d'Etudes et de Recherche sur le Médicament de Normandie (CERMN), UFR des Sciences Pharmaceutiques, Université de Caen de Basse-Normandie, France, for the minimal costs of shipping fees. We thank Damien Monet for his assistance in the cavity generation and analyses., ANR-13-BSV8-0009,HeliDEAD,Les ARN hélicases à boite DEAD: quels sont leurs rôles, leurs partenaires, leurs substrats ARN et comment elles fonctionnent.(2013), ANR-11-LABX-0011,DYNAMO,Dynamique des membranes transductrices d'énergie : biogénèse et organisation supramoléculaire.(2011), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Faculté des Sciences de Bizerte, Bioinformatique structurale, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), ANR-11-LABX-0011/11-LABX-0011,DYNAMO,Dynamique des membranes transductrices d'énergie : biogénèse et organisation supramoléculaire.(2011), Institut de biologie physico-chimique (IBPC)

المصدر: Molecular and Biochemical Parasitology
Molecular and Biochemical Parasitology, 2018, 226, pp.9-19. ⟨10.1016/j.molbiopara.2018.10.001⟩
Molecular and Biochemical Parasitology, Elsevier, 2018, 226, pp.9-19. ⟨10.1016/j.molbiopara.2018.10.001⟩

مصطلحات موضوعية: Hippuristanol, 0301 basic medicine, Antifungal Agents, MESH: Sequence Homology, Amino Acid, ATPase, Protozoan Proteins, Gene Expression, MESH: Protein Structure, Secondary, MESH: Amino Acid Sequence, Protein Structure, Secondary, MESH: Eukaryotic Initiation Factor-4A, MESH: Recombinant Proteins, Mice, chemistry.chemical_compound, Adenosine Triphosphate, MESH: Cholesterol, MESH: Genetic Vectors, MESH: Adenosine Triphosphate, MESH: Animals, MESH: Trypanocidal Agents, Cloning, Molecular, Leishmania infantum, MESH: Protozoan Proteins, Conserved Sequence, Ergosterol, MESH: Conserved Sequence, MESH: Kinetics, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], MESH: Escherichia coli, Trypanocidal Agents, RNA Helicase A, Recombinant Proteins, MESH: Leishmania infantum, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Cholesterol, Biochemistry, Translation-initiation factor, MESH: Drug Repositioning, Protein Binding, RNA helicase, MESH: Gene Expression, Genetic Vectors, MESH: Sequence Alignment, MESH: Binding, Competitive, Biology, Binding, Competitive, Drug design, 03 medical and health sciences, Escherichia coli, Animals, Humans, MESH: Protein Binding, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Protein Interaction Domains and Motifs, MESH: Cloning, Molecular, Amino Acid Sequence, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], Binding site, MESH: Mice, Molecular Biology, MESH: Protein Interaction Domains and Motifs, Binding Sites, MESH: Humans, Sequence Homology, Amino Acid, MESH: RNA, Helminth, 030102 biochemistry & molecular biology, Drug Repositioning, RNA, Helicase, MESH: Antifungal Agents, Kinetics, 030104 developmental biology, MESH: Binding Sites, chemistry, eIF4A, Eukaryotic Initiation Factor-4A, Nucleic acid, biology.protein, Parasitology, RNA, Helminth, Sequence Alignment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1cab00f461442b882b9cc5b78e1a41
https://doi.org/10.1016/j.molbiopara.2018.10.001

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4

Conserved domains and structure prediction of human cytomegalovirus UL27 protein

المؤلفون: Gaël Champier, Anthony Couvreux, Laurène Trapes, Sébastien Cotin, Sébastien Hantz, François Denis, Sophie Alain, Serge Bouaziz

المساهمون: Biologie moléculaire et cellulaire des microorganismes (EA3175), Université de Limoges (UNILIM)-Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST FR CNRS 3503)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Bactériologie, Virologie, Hygiène [CHU Limoges], CHU Limoges, Laboratoire d'informatique Fondamentale de Marseille - UMR 6166 (LIF), Université de la Méditerranée - Aix-Marseille 2-Université de Provence - Aix-Marseille 1-Centre National de la Recherche Scientifique (CNRS), Unité de Pharmacologie Chimique et Génétique (UPCG - UMR_S 640/UMR 8151), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Descartes - Paris 5 (UPD5)-Institut des sciences du Médicament -Toxicologie - Chimie - Environnement (IFR71), Institut National de la Santé et de la Recherche Médicale (INSERM)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Paris Descartes - Paris 5 (UPD5)-Institut de Chimie du CNRS (INC), Bouaziz, Serge, Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut des sciences du Médicament -Toxicologie - Chimie - Environnement (IFR71), Institut de Recherche pour le Développement (IRD)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Antiviral Therapy
Antiviral Therapy, International Medical Press, 2019, 14 (5), pp.663-72
Antiviral Therapy, 2019, 14 (5), pp.663-72
HAL
ResearcherID

مصطلحات موضوعية: Human cytomegalovirus, MESH: Sequence Analysis, DNA, viruses, Cytomegalovirus, MESH: Amino Acid Sequence, medicine.disease_cause, chemistry.chemical_compound, MESH: Structure-Activity Relationship, Pharmacology (medical), Peptide sequence, Conserved Sequence, Mutation, MESH: Conserved Sequence, MESH: Drug Resistance, Viral, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], virus diseases, Maribavir, Cell biology, Phosphotransferases (Alcohol Group Acceptor), Infectious Diseases, MESH: Antiviral Agents, MESH: Cytomegalovirus, MESH: Mutation, [SDV.BBM.BS] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Sequence analysis, Molecular Sequence Data, MESH: Sequence Alignment, Sequence alignment, Biology, Antiviral Agents, Herpesviridae, Structure-Activity Relationship, Drug Resistance, Viral, medicine, Humans, Amino Acid Sequence, Pharmacology, MESH: Ribonucleosides, MESH: Humans, MESH: Molecular Sequence Data, Sequence Analysis, DNA, medicine.disease, Virology, MESH: Phosphotransferases (Alcohol Group Acceptor), MESH: DNA, Viral, chemistry, DNA, Viral, Benzimidazoles, Ribonucleosides, MESH: Benzimidazoles, Sequence Alignment, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dac8e709bf4d7ae85991f44bec4d3bd
https://hal.archives-ouvertes.fr/hal-02122495

5

Peptidomic analysis of the host-defense peptides in skin secretions of the Trinidadian leaf frog Phyllomedusa trinitatis (Phyllomedusidae)

المؤلفون: Milena Mechkarska, J. Michael Conlon, Laurent Coquet, Thierry Jouenne, Jérôme Leprince, Renoir J. Auguste, Maria Luisa Mangoni

المساهمون: The University of the West Indies, Plate-forme de Protéomique PISSARO, Institute for Research and Innovation in Biomedicine (IRIB), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Plate-Forme de Recherche en Imagerie Cellulaire de Haute-Normandie (PRIMACEN), Normandie Université (NU)-Normandie Université (NU)-Institute for Research and Innovation in Biomedicine (IRIB), Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Department of Biochemical Sciences 'Rossi Fanelli', Institut Pasteur, Fondation Cenci Bolognetti - Istituto Pasteur Italia, Fondazione Cenci Bolognetti, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], University of Ulster, Support for this study was provided to MM by Campus Research and Publication Fund (CRP.3.NOV16.8 grant #26600-457118) and a Study and Travel grant for visiting Ulster University from the University of the West Indies., Special thanks are extended to Mr. Romano McFarlane, Wildlife Section, Forestry Division for help with obtaining the frog collection permit. The authors thank Mr. Mike Rutherford, curator at the UWIZM, for providing help, advice and reagents to deposit the frog voucher specimens and Philip Chan Tchi Song of the PISSARO platform for MS/MS measurements.

المصدر: Comparative Biochemistry and Physiology-Part D: Genomics and Proteomics
Comparative Biochemistry and Physiology-Part D: Genomics and Proteomics, Elsevier, 2018, 28, pp.72-79. ⟨10.1016/j.cbd.2018.06.006⟩

مصطلحات موضوعية: 0301 basic medicine, Phyllomedusa tarsius, Male, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Peptide, MESH: Amino Acid Sequence, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, Phyllomedusa, MESH: Anti-Infective Agents/analysis, Anti-Infective Agents, Phylloseptin, Candida albicans, [SDV.BC.IC]Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB], MESH: Amphibian Proteins/pharmacology, molecular biology, genetics, MESH: Animals, Peptide sequence, Conserved Sequence, Plasticin, Skin, chemistry.chemical_classification, MESH: Candidiasis/drug therapy, MESH: Conserved Sequence, biology, Candidiasis, Bacterial Infections, MESH: Antimicrobial Cationic Peptides/analysis, MESH: Anti-Infective Agents/pharmacology, Biochemistry, Host-defense peptide, Female, Anura, MESH: Bacteria/drug effects, MESH: Skin/metabolism, MESH: Antimicrobial Cationic Peptides/pharmacology, Antioxidant peptide, MESH: Candida albicans/drug effects, Amphibian Proteins, Frog skin, 03 medical and health sciences, Dermaseptin, MESH: Anti-Infective Agents/metabolism, Animals, Humans, biochemistry, Amino Acid Sequence, MESH: Bacterial Infections/drug therapy, MESH: Antimicrobial Cationic Peptides/metabolism, MESH: Humans, Edman degradation, Bacteria, antioxidant peptide, dermaseptin, frog skin, host-defense peptide, phyllomedusa, phylloseptin, plasticin, physiology, MESH: Anura/metabolism, Phyllomedusa trinitatis, MESH: Amphibian Proteins/metabolism, MESH: Amphibian Proteins/analysis, biology.organism_classification, MESH: Male, MESH: Skin/chemistry, 030104 developmental biology, chemistry, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, Frog Skin, MESH: Female, Antimicrobial Cationic Peptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d8ac132402e20bcd83e05d84ec442a
https://hal-normandie-univ.archives-ouvertes.fr/hal-01973119

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6

Polar N-terminal Residues Conserved in Type 2 Secretion Pseudopilins Determine Subunit Targeting and Membrane Extraction Steps during Fibre Assembly

المؤلفون: Ingrid Guilvout, Alexandra East, Guy Tran Van Nhieu, Olivera Francetic, Nathalie Nadeau, Peter J. Bond, Javier Santos-Moreno

المساهمون: Centre interdisciplinaire de recherche en biologie (CIRB), Labex MemoLife, École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Collège de France (CdF (institution))-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Collège de France (CdF (institution))-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris Diderot - Paris 7 (UPD7), Université Paris sciences et lettres (PSL)-Collège de France (CdF (institution)), University of Cambridge [UK] (CAM), Biochimie des Interactions Macromoléculaires / Biochemistry of Macromolecular Interactions, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Systèmes macromoléculaires et Signalisation, Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Agency for science, technology and research [Singapore] (A*STAR), National University of Singapore (NUS), This work was funded by the ANR FiberSpace grant N°ANR-14-CE09-0004. Javier Santos-Moreno was funded by a fellowship from the Basque Government, and Alexandra East was supported by an EPSRC PhD studentship. The computational work benefited from use of the Darwin Supercomputer of the University of Cambridge High Performance Computing Service (http://www.hpc.cam.ac.uk/), provided by Dell Inc. using Strategic Research, Infrastructure Funding from the Higher Education Funding Council for England., We thank Evelyne Richet and Jenny-Lee Thomassin for insightful comments and critical reading of the manuscript. We thank Cesar Valencia and Jenny-Lee Thomassin for help with IF data processing and statistical analysis, Mariette Bonnet for help and advice, and Stéphane Romero for stimulating discussions about biological fibres. We are grateful to all members of the Laboratory of Intercellular Communication and Microbial Infections, the Laboratory for Macromolecular Systems and Signalling and of the Biochemstry of Macromolecular Interactions Unit for helpful discussions and friendly support. We thank Gouzel Karimova and Daniel Ladant for the strains, plasmids, and advice concerning the BAC2H analysis., ANR-14-CE09-0004,FiberSpace,Pili de type IV et pseudopili: structure, dynamique, assemblage et fonction moléculaire(2014), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Collège de France (CdF (institution))-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Francetic, Olivera, Appel à projets générique - Pili de type IV et pseudopili: structure, dynamique, assemblage et fonction moléculaire - - FiberSpace2014 - ANR-14-CE09-0004 - Appel à projets générique - VALID

المصدر: Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2017, 429 (11), pp.1746-1765. ⟨10.1016/j.jmb.2017.04.005⟩
Journal of Molecular Biology, 2017, 429 (11), pp.1746-1765. ⟨10.1016/j.jmb.2017.04.005⟩

مصطلحات موضوعية: 0301 basic medicine, Protein subunit, 030106 microbiology, Mutant, membrane proteins, Flagellum, Molecular Dynamics Simulation, Pilus, 03 medical and health sciences, MESH: Mutant Proteins, Structural Biology, Type II Secretion Systems, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, MESH: Protein Binding, MESH: Molecular Dynamics Simulation, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Molecular Biology, Conserved Sequence, Phospholipids, MESH: Phospholipids, MESH: Type II Secretion Systems, MESH: Conserved Sequence, biology, MESH: Protein Multimerization, Cell Membrane, immunofluorescence microscopy, molecular dynamics simulations, N-methylation, type 4 fibre assembly, MESH: Fimbriae Proteins, N-terminus, 030104 developmental biology, Membrane protein, Biochemistry, Chaperone (protein), Pilin, biology.protein, Biophysics, Mutant Proteins, Fimbriae Proteins, Protein Multimerization, Protein Binding, MESH: Cell Membrane

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::022b2d80464c28bf227f46bdbbb0cae7
https://hal-pasteur.archives-ouvertes.fr/pasteur-01602354

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7

Micro-time scale genome evolution among natural populations of Streptomyces

المؤلفون: TOUSSAINT, Maxime, Tidjani, Abdoul-Razak, Lorenzi, Jean-Noël, Hotel, Laurence, Lespinet, Olivier, Cyril, Bontemps, Leblond, Pierre

المساهمون: Dynamique des Génomes et Adaptation Microbienne (DynAMic), Université de Lorraine (UL)-Institut National de la Recherche Agronomique (INRA), Institut de génétique et microbiologie [Orsay] (IGM), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS)

المصدر: International Symposium of the Biology of Actinomycetes
International Symposium of the Biology of Actinomycetes, May 2017, Jeju, South Korea

مصطلحات موضوعية: MESH: Chromosomes, Bacterial, MESH: Base Pairing, MESH: Streptomyces, MESH: Amino Acid Sequence, MESH: Base Sequence, MESH: Sequence Homology, Nucleic Acid, [SDV.EE.ECO]Life Sciences [q-bio]/Ecology, environment/Ecosystems, MESH: Plasmids, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], MESH: Polymorphism, Genetic, MESH: Species Specificity, MESH: Bacterial Proteins, MESH: Restriction Mapping, MESH: Repetitive Sequences, Nucleic Acid, MESH: Conserved Sequence, MESH: Molecular Sequence Data, [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE], MESH: Sigma Factor, MESH: Open Reading Frames, MESH: Sequence Deletion, MESH: Chromosome Inversion, MESH: DNA, Bacterial, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, MESH: Multigene Family, MESH: Recombination, Genetic, MESH: Genes, Bacterial

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::fef9afad07ce96a8dde26bf1ee643343
https://hal.univ-lorraine.fr/hal-01625360

8

Homologous Capsid Proteins Testify to the Common Ancestry of Retroviruses, Caulimoviruses, Pseudoviruses, and Metaviruses

المؤلفون: Eugene V. Koonin, Mart Krupovic

المساهمون: Biologie Moléculaire du Gène chez les Extrêmophiles (BMGE), Institut Pasteur [Paris] (IP), National Center for Biotechnology Information (NCBI), E.V.K. is supported by intramural funds of the U.S. Department of Health and Human Services (to the National Library of Medicine)., Institut Pasteur [Paris]

المصدر: Journal of Virology
Journal of Virology, 2017, 91 (12), pp.e00210-17. ⟨10.1128/JVI.00210-17⟩
Journal of Virology, American Society for Microbiology, 2017, 91 (12), pp.e00210-17. ⟨10.1128/JVI.00210-17⟩

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Retroelements, MESH: Sequence Homology, Amino Acid, [SDV]Life Sciences [q-bio], Immunology, MESH: Sequence Alignment, Sequence alignment, Caulimoviridae, Microbiology, Conserved sequence, Evolution, Molecular, MESH: Viruses, 03 medical and health sciences, MESH: Retroelements, Phylogenetics, Virology, reverse-transcribing viruses, Metaviridae, MESH: Phylogeny, Letter to the Editor, Conserved Sequence, Phylogeny, MESH: Capsid Proteins, MESH: Evolution, Molecular, Genetics, virus evolution, Ty3/Gypsy and Ty1/Copia LTR retrotransposons, MESH: Conserved Sequence, biology, Sequence Homology, Amino Acid, structural polyprotein Gag, Pseudoviridae, biology.organism_classification, 3. Good health, nucleocapsid proteins, 030104 developmental biology, Retroviridae, Capsid, Insect Science, Viral evolution, Viruses, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Capsid Proteins, Sequence Alignment, MESH: Models, Molecular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03502644cc4ca4a6cf255c512e1f027e
https://hal-pasteur.archives-ouvertes.fr/pasteur-01977363

9

Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator

المؤلفون: Charlotte Passemar, Alexandre Pawlik, Wladimir Malaga, Flavie Moreau, Mamadou Daffé, Carlos Martin, Roland Brosch, Christophe Guilhot, Catherine Astarie-Dequeker, Françoise Laval, Jesús Gonzalo-Asensio

المساهمون: University of Zaragoza - Universidad de Zaragoza [Zaragoza], Institut de pharmacologie et de biologie structurale (IPBS), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Pathogénomique mycobactérienne intégrée - Integrated Mycobacterial Pathogenomics, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), This work was supported in part by the Juan de la Cierva Programme JCI-2009-03799 from the Spanish Ministry of Science and Innovation (to J.G.-A.), the Centre National de la Recherche Scientifique, the Fondation pour la Recherche Médicale ('Equipe FRM' DEQ20090515399 and DEQ20130326471), the European Union 7th Framework Programme (Contracts NEWTBVAC 241745, MM4TB 260872, and FEDER/POCTEFA/REFBIO EFA237/11), the Spanish Ministry of Economy and Competitiveness (Contracts BIO2011-23555 and FIS12/1970), and the Région Midi-Pyrénées (CPER 2007-2013) for the scientific project and for the ASB3 animal facility., We thank Dr. Geanncarlo Lugo-Villarino and Dr. Stephen V. Gordon for critical reading of the manuscript. We thank the members of the Genotoul platforms TRI and ANEXPLO (Institut de Pharmacologie et de Biologie Structurale) for epifluorescence microscopy imaging and for animal experiments, respectively, and Dr. Marie-Agnès Dillies and Dr. Jean-Yves Coppée from the Transcriptome Platform PF2 at the Institut Pasteur for advice., European Project: 241745,EC:FP7:HEALTH,FP7-HEALTH-2009-single-stage,NEWTBVAC(2010), European Project: 260872,EC:FP7:HEALTH,FP7-HEALTH-2010-single-stage,MM4TB(2011), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS)

المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (31), pp.11491-11496. ⟨10.1073/pnas.1406693111⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2014, 111 (31), pp.11491-11496. ⟨10.1073/pnas.1406693111⟩
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname

مصطلحات موضوعية: adaptation, MESH: Animals, MESH: Phylogeny, Conserved Sequence, Phylogeny, Genetics, Mycobacterium bovis, Multidisciplinary, Virulence, Genetic transfer, Biological Sciences, Biological Evolution, 3. Good health, MESH: Cattle, Host-Pathogen Interactions, MESH: Mycobacterium tuberculosis / genetics, MESH: Conserved Sequence / genetics, Locus (genetics), MESH: Mycobacterium tuberculosis / pathogenicity, Biology, Polymorphism, Single Nucleotide, MESH: Biological Evolution, Mycobacterium, Microbiology, Mycobacterium tuberculosis, Bacterial Proteins, evolution, MESH: Virulence / genetics, Animals, Humans, Tuberculosis, Secretion, MESH: Mycobacterium bovis / pathogenicity, MESH: Bacterial Proteins / metabolism, Alleles, Antigens, Bacterial, MESH: Humans, MESH: Alleles, MESH: Host-Pathogen Interactions, zoonosis, biology.organism_classification, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, MESH: Mycobacterium / genetics, Mutagenesis, Insertional, Regulon, MESH: Mutagenesis, Insertional, MESH: Bacterial Proteins / genetics, MESH: Gene Deletion, MESH: Mutation / genetics, MESH: Mycobacterium bovis / genetics, Mutation, Cattle, MESH: Polymorphism, Single Nucleotide / genetics, MESH: Tuberculosis / microbiology, MESH: Tuberculosis / genetics, Mycobacterium africanum, MESH: Antigens, Bacterial, Gene Deletion

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d71c0a455726970b4a1c9fe0ec44b4
https://doi.org/10.1073/pnas.1406693111

10

Selective Methylation of Histone H3 Variant H3.1 Regulates Heterochromatin Replication

المؤلفون: Philipp Voigt, Danny Reinberg, Yannick Jacob, Mark T.A. Donoghue, Chantal LeBlanc, Charles J Underwood, Joseph S. Brunzelle, Vanessa Mongeon, Jean-François Couture, Robert A. Martienssen, E. Bergamin, Scott D. Michaels

المساهمون: Cold Spring Harbor Laboratory (CSHL), University of Ottawa [Ottawa], Northwestern Synchrotron Research Center (NSRC), Northwestern Synchrotron, Indiana University [Bloomington], Indiana University System, New York University School of Medicine (NYU), New York University School of Medicine, NYU System (NYU)-NYU System (NYU)

المصدر: iScience
iScience, Elsevier, 2014, 343 (6176), pp.1249-1253. ⟨10.1126/science.1248357⟩

مصطلحات موضوعية: DNA Replication, Threonine, [SDV]Life Sciences [q-bio], Molecular Sequence Data, Arabidopsis, Mitosis, MESH: Catalytic Domain, MESH: DNA Replication, MESH: Amino Acid Sequence, MESH: Arabidopsis Proteins, Biology, Crystallography, X-Ray, Methylation, Article, Epigenesis, Genetic, Histones, MESH: Methylation, Histone H3, Histone H1, Gene Expression Regulation, Plant, Catalytic Domain, Heterochromatin, MESH: Methyltransferases, Histone methylation, Histone H2A, Histone code, MESH: Arabidopsis, Amino Acid Sequence, MESH: Epigenesis, Genetic, MESH: Threonine, MESH: Gene Expression Regulation, Plant, Conserved Sequence, MESH: Histones, Genetics, MESH: Molecular Sequence Data, MESH: Conserved Sequence, Multidisciplinary, Arabidopsis Proteins, EZH2, Methyltransferases, MESH: Mitosis, MESH: Crystallography, X-Ray, 3. Good health, MESH: Heterochromatin, MESH: Protein Processing, Post-Translational, Histone methyltransferase, Heterochromatin protein 1, Protein Processing, Post-Translational

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddafe6bc2dbe2ac2f498db3891fff342
https://doi.org/10.1126/science.1248357

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