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المؤلفون: Huot, Nicolas, Rascle, Philippe, Petitdemange, Caroline, Contreras, Vanessa, Stürzel, Christina M., Baquero, Eduard, Harper, Justin L., Passaes, Caroline, Legendre, Rachel, Varet, Hugo, Madec, Yoann, Sauermann, Ulrike, Stahl-Hennig, Christiane, Nattermann, Jacob, Saez-Cirion, Asier, Le Grand, Roger, Keith Reeves, R., Paiardini, Mirko, Kirchhoff, Frank, Jacquelin, Beatrice, Müller-Trutwin, Michaela
المساهمون: Varet, Hugo, Organisation et montée en puissance d'une Infrastructure Nationale de Génomique - - France-Génomique2010 - ANR-10-INBS-0009 - INBS - VALID, Infrastructures - Infrastructure nationale pour la modélisation des maladies infectieuses humaines - - IDMIT2011 - ANR-11-INBS-0008 - INBS - VALID, Développment d'une infrastructure française distribuée coordonnée - - France-BioImaging2010 - ANR-10-INBS-0004 - INBS - VALID, HIV, Inflammation et persistance - HIV, Inflammation and Persistence, Institut Pasteur [Paris] (IP), Immunologie des maladies virales, auto-immunes, hématologiques et bactériennes (IMVA-HB), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, University of Ulm (UUlm), Virologie Structurale - Structural Virology, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Yerkes National Primate Research Center [Lawrenceville, GA], Emory University [Atlanta, GA], Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Pôle Biomics (C2RT), Centre de Ressources et de Recherche Technologique - Center for Technological Resources and Research (C2RT), Institut Pasteur [Paris] (IP)-Institut Pasteur [Paris] (IP), Epidémiologie des Maladies Emergentes - Emerging Diseases Epidemiology, Pasteur-Cnam Risques infectieux et émergents (PACRI), Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM), German Primate Center - Deutsches Primatenzentrum -- Leibniz Insitute for Primate Research -- [Göttingen, Allemagne] (GPC - DPZ), Universitätsklinikum Bonn (UKB), Immunologie des Maladies Virales et Autoimmunes (IMVA - U1184), Université Paris-Sud - Paris 11 (UP11)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Harvard Medical School [Boston] (HMS), Emory University School of Medicine, The Biomics Platform (C2RT, Institut Pasteur) is supported by France Génomique (ANR-10-INBS-09-09) and IBISA NH was supported by the VRI Labex, the Fondation Jacquelin Beytout and Institut Pasteur, and PR was recipient of a PhD fellowship from the University Paris Diderot, Sorbonne Paris Cité. C.P. was supported by a MSDAvenir Postdoctoral Fellowship Grant. FK was supported by the DFG (CRC 1279 and SPP 1923. We would like to acknowledge grant support from ANRS, the Fondation Jacqueline Beytout, and the Fondation Les Ailes to M.M.T., from the NIH (R01AI143457) to M.M.T. and R.K.R. and from MSDAvenir to A.S.C. and M.M.T., J.L.H. and M.P. were supported by NIH grant R01AI116379 to M.P. and by ORIP/OD award P51OD011132 to Yerkes National Primate Research Center. J.N. was supported by the DFG (SPP 1937, SFB TR57), the Hector Foundation, and the DZIF (TTU-HIV). We gratefully acknowledge the support to IDMIT from the French government: Investments for the Future program for infrastructures (PIA) through the ANR-11-INBS-0008 grant as well as from the PIA grant ANR-10-EQPX-02-01 to the FlowCyTech facility at IDMIT. We equally acknowledge the Investments for Future grant ANR-10–INSB–04 to support the UtechS Photonic BioImaging (Imagopole) and C2RT facilities at Institut Pasteur., ANR-10-INBS-0009,France-Génomique,Organisation et montée en puissance d'une Infrastructure Nationale de Génomique(2010), ANR-11-INBS-0008,IDMIT,Infrastructure nationale pour la modélisation des maladies infectieuses humaines(2011), ANR-10-INBS-0004,France-BioImaging,Développment d'une infrastructure française distribuée coordonnée(2010), HIV, Inflammation et persistance, Institut Pasteur [Paris], Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris]-Institut Pasteur [Paris], Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM), Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)
المصدر: Nature Communications
Nature Communications, 2021, 12 (1), pp.1282. ⟨10.1038/s41467-021-21402-1⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.1282. ⟨10.1038/s41467-021-21402-1⟩
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, MESH: Killer Cells, Natural, MESH: Cell Differentiation, Lymphoid Tissue, Science, animal diseases, [SDV]Life Sciences [q-bio], MESH: Simian Immunodeficiency Virus, Simian Acquired Immunodeficiency Syndrome, Fluorescent Antibody Technique, MESH: Algorithms, MESH: Lymph Nodes, MESH: Flow Cytometry, NK cells, Article, MESH: Chlorocebus aethiops, Chlorocebus aethiops, Animals, Humans, MESH: Animals, MESH: Fluorescent Antibody Technique, MESH: K562 Cells, Retrovirus, MESH: Humans, MESH: Transcriptome, MESH: Macaca, MESH: CD4-Positive T-Lymphocytes, Cell Differentiation, Flow Cytometry, MESH: Male, Killer Cells, Natural, [SDV] Life Sciences [q-bio], MESH: NK Cell Lectin-Like Receptor Subfamily C, Viral infection, MESH: Lymphoid Tissue, Macaca, Lymph node, Female, Simian Immunodeficiency Virus, Lymph Nodes, MESH: Simian Acquired Immunodeficiency Syndrome, K562 Cells, NK Cell Lectin-Like Receptor Subfamily C, Transcriptome, MESH: Female, Algorithms
وصف الملف: application/pdf
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المؤلفون: Goehrig, Delphine, Nigri, Jérémy, Samain, Rémi, Wu, Zhichong, Cappello, Paola, Gabiane, Gaëlle, Zhang, Xinyi, Zhao, Yajie, Kim, In-San, Chanal, Marie, Curto, Roberta, Hervieu, Valerie, de La Fouchardière, Christelle, Novelli, Francesco, Milani, Pascale, Tomasini, Richard, Bousquet, Corinne, Bertolino, Philippe, Hennino, Ana
المساهمون: Physiopathologie, diagnostic et traitements des maladies osseuses / Pathophysiology, Diagnosis & Treatments of Bone Diseases (LYOS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de Recherche en Cancérologie de Marseille (CRCM), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Aix Marseille Université (AMU), Université Grenoble Alpes - UFR Pharmacie (UGA UFRP), Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), USC Institute for Creative Technologies (USC-ICT), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL), Tumeurs endocrines digestives : mécanismes de la tumorigenèse et de la progression tumorale, Centre Léon Bérard [Lyon], Génétique Humaine des Maladies Infectieuses (Inserm U980), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire Joliot Curie, École normale supérieure - Lyon (ENS Lyon)-Centre National de la Recherche Scientifique (CNRS), Institut de médecine moléculaire de Rangueil (I2MR), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-IFR150-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de Recherche en Cancérologie de Lyon (UNICANCER/CRCL), Centre Léon Bérard [Lyon]-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), École Pratique des Hautes Études (EPHE), École normale supérieure de Lyon (ENS de Lyon)-Centre National de la Recherche Scientifique (CNRS), Université de Toulouse (UT)-Université de Toulouse (UT)- Institut Fédératif de Recherche Bio-médicale Institution (IFR150)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Bidaut, Ghislain, Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées- Institut Fédératif de Recherche Bio-médicale Institution (IFR150)-Institut National de la Santé et de la Recherche Médicale (INSERM)
المصدر: Gut
Gut, BMJ Publishing Group, 2019, 68 (4), pp.693-707. ⟨10.1136/gutjnl-2018-317570⟩
Gut, 2019, 68 (4), pp.693-707. ⟨10.1136/gutjnl-2018-317570⟩مصطلحات موضوعية: MESH: Extracellular Matrix Proteins, T-Lymphocytes, animal diseases, [SDV]Life Sciences [q-bio], pancreatic cancer, t lymphocytes, Fluorescent Antibody Technique, MESH: Flow Cytometry, CD8-Positive T-Lymphocytes, Microscopy, Atomic Force, Transgenic, immune response, Mice, Transforming Growth Factor beta, MESH: Tumor Microenvironment, Tumor Microenvironment, MESH: Animals, MESH: Fluorescent Antibody Technique, MESH: Microscopy, Atomic Force, Microscopy, Extracellular Matrix Proteins, Gastroenterology, Atomic Force, Flow Cytometry, MESH: CD8-Positive T-Lymphocytes, Immunohistochemistry, [SDV] Life Sciences [q-bio], Editorial Commentary, Pancreatic Ductal, Adenocarcinoma, Animals, Carcinoma, Pancreatic Ductal, Fibroblasts, Humans, Macrophages, Mice, Transgenic, Pancreatic Neoplasms, Paracrine Communication, MESH: Pancreatic Neoplasms, MESH: Mice, Transgenic, chemical and pharmacologic phenomena, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, MESH: Paracrine Communication, Pancreas, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, MESH: Mice, MESH: Transforming Growth Factor beta, MESH: Humans, MESH: Carcinoma, Pancreatic Ductal, Carcinoma, MESH: Adenocarcinoma, MESH: Macrophages, MESH: Immunohistochemistry, biochemical phenomena, metabolism, and nutrition, MESH: Fibroblasts, bacteria
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المؤلفون: J.-F. Dufour, Jean-Marc Reynes, A. Bour, X. Plaisancie
المساهمون: Service de médecine interne et post-urgence [Bourg-en-Bresse], Centre Hospitalier Fleyriat [Bourg en Bresse], Centre National de Référence des Hantavirus - Biologie des Infections Virales Emergentes (CNR-UBIVE), Institut Pasteur [Paris], Institut Pasteur [Paris] (IP)
المصدر: La Revue De Médecine Interne
La Revue De Médecine Interne, Elsevier, 2016, 37 (7), pp.493-496. ⟨10.1016/j.revmed.2015.10.343⟩
La Revue de Médecine Interne
La Revue de Médecine Interne, 2016, 37 (7), pp.493-496. ⟨10.1016/j.revmed.2015.10.343⟩مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, MESH: Acute Kidney Injury, viruses, 030106 microbiology, Hemorrhagic fever with renal syndrome, 03 medical and health sciences, MESH: Hemorrhagic Fever with Renal Syndrome, MESH: Transaminases, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Internal Medicine, Medicine, MESH: Fluorescent Antibody Technique, MESH: Thrombocytopenia, Seoul virus, Hantavirus, Gynecology, MESH: Humans, business.industry, Fièvre hémorragique avec syndrome rénal, MESH: Hantavirus, Gastroenterology, virus diseases, MESH: Adult, MESH: Seoul, MESH: Male, 3. Good health, MESH: France, Virus Séoul, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, France, business
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المؤلفون: Valérie Gouyer, Jean-Luc Desseyn, Céline Portal, Frédéric Gottrand
المساهمون: Lille Inflammation Research International Center - U 995 (LIRIC), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)
المصدر: médecine/sciences
médecine/sciences, EDP Sciences, 2017, 33 (5), pp.478-480. ⟨10.1051/medsci/20173305006⟩
médecine/sciences, 2017, 33 (5), pp.478-480. ⟨10.1051/medsci/20173305006⟩مصطلحات موضوعية: MESH: Cell Differentiation, 0301 basic medicine, MESH: Mice, Transgenic, [SDV]Life Sciences [q-bio], Transgene, Mucous cell, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, In vivo, MESH: Mucus, MESH: Gene Expression Regulation, Developmental, MESH: Animals, MESH: Mice, MESH: Fluorescent Antibody Technique, ComputingMilieux_MISCELLANEOUS, Regulation of gene expression, MESH: Cells, MESH: Humans, MESH: Mucin-5B, Mucin, MESH: Embryo, Mammalian, Embryo, General Medicine, MESH: Fluorescent Dyes, MESH: Male, Cell biology, 030104 developmental biology, MESH: Drug Evaluation, Preclinical, MESH: Female, Ex vivo
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d82661f82ffde8b278b624b6230630
https://doi.org/10.1051/medsci/20173305006 -
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المؤلفون: M. Alejandra Tortorici, Danilo Dubrau, Norbert Tautz, Félix A. Rey
المساهمون: Universität zu Lübeck [Lübeck], Virologie Structurale - Structural Virology, Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], NT was funded by the German Science Foundation (DFG) (Grant TA 218 4-1) and by intramural funding from the University of Luebeck. MAT and FAR acknowledge support from the Institut Pasteur and the CNRS., We especially thank S. Schwindt and M. Alexander for excellent technical assistance. We are grateful to E. J. Dubovi (Cornell University, Ithaca, NY) for antibody 8.12.7, T. Rümenapf and B. Lamp (University of Veterinary Medicine, Vienna, Austria) for providing antibodies GH4A1 [4B7], GL4B1, GLBVD5A1 [11C] and GLBVD5B1 [9A], H.-J. Thiel for providing anti-E2 antibody (Justus-Liebig University, Gießen), S. Lemon (UNC, Chapel Hill, NC) for providing us with the Huh7-T7 cell line, and G. Sutter (LMU, Munich, Germany) for the MVA-T7pol vaccinia virus. We especially thank O. Isken and all members of the Tautz group for helpful discussion. We also thank I. König (Institute of Medical Biometry and Statistics, University of Luebeck) for help with the statistical analysis, A. Haouz (Plate forme de Cristallographie, Pasteur Institute) for help with crystallization trials, P. Guardado-Calvo and S. Duquerroy for initial help in model building and P. Vachette for helpful discussions. We are grateful to SLS, ESRF and Soleil synchrotrons staff for providing access to synchrotron facilities., Universität zu Lübeck = University of Lübeck [Lübeck], Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)
المصدر: PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2017, 13 (2), pp.e1006134. ⟨10.1371/journal.ppat.1006134⟩
PLoS Pathogens, Vol 13, Iss 2, p e1006134 (2017)
'PLoS Pathogens ', vol: 13, pages: e1006134-1-e1006134-30 (2017)
PLoS Pathogens, 2017, 13 (2), pp.e1006134. ⟨10.1371/journal.ppat.1006134⟩مصطلحات موضوعية: 0301 basic medicine, RNA viruses, viruses, Fluorescent Antibody Technique, Viral Nonstructural Proteins, medicine.disease_cause, Pathology and Laboratory Medicine, Crystallography, X-Ray, Virus Replication, Biochemistry, Virions, MESH: Dogs, Sense (molecular biology), Morphogenesis, Medicine and Health Sciences, MESH: Animals, MESH: Serine Endopeptidases, lcsh:QH301-705.5, MESH: Fluorescent Antibody Technique, biology, Chemistry, MESH: RNA Helicases, Serine Endopeptidases, Viral Replication Complex, virus diseases, Proteases, Poxviruses, Vaccinia Virus, Cell biology, Enzymes, MESH: Mutagenesis, Site-Directed, Medical Microbiology, MESH: RNA, Viral, Viral Pathogens, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Viruses, MESH: Virion, RNA, Viral, Pathogens, RNA Helicases, Research Article, lcsh:Immunologic diseases. Allergy, MESH: Virus Assembly, Viral protein, Immunology, Blotting, Western, RNA-dependent RNA polymerase, Viral Structure, Microbiology, Cell Line, 03 medical and health sciences, Dogs, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Virology, Genetics, medicine, MESH: Blotting, Western, Animals, Molecular Biology, Microbial Pathogens, NS3, Flaviviruses, Virus Assembly, MESH: Virus Replication, Organisms, Virion, RNA, Biology and Life Sciences, Proteins, RNA virus, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, MESH: Crystallography, X-Ray, Molecular biology, MESH: Morphogenesis, Viral Replication, MESH: Cell Line, 030104 developmental biology, Viral replication, lcsh:Biology (General), Viral replication complex, Pestivirus, Enzymology, Mutagenesis, Site-Directed, MESH: Viral Nonstructural Proteins, Parasitology, lcsh:RC581-607, DNA viruses, MESH: Pestivirus, Developmental Biology
وصف الملف: application/pdf
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المؤلفون: Fabio Midulla, Marie Legendre, Woolf T. Walker, Laura Behan, Andrew Bush, Deborah Snijders, Angelo Barbato, Robert A. Hirst, Sharon D. Dell, Claudia E. Kuehni, Bernhard Rindlisbacher, Margaret W. Leigh, Philipp Latzin, Estelle Escudier, Samuel Collins, Mark Jorissen, Thomy Tonia, Jean-François Papon, Francesca Santamaria, Claire Hogg, Amelia Shoemark, Myrofora Goutaki, Claudius Werner, Andrea Titieni, Daan Caudri, Heymut Omran, Ernst Eber, Beatrice Redfern, Jane S. Lucas, Kim G. Nielsen, David Rigau, Petr Pohunek
المساهمون: Lucas, Jane S, Barbato, Angelo, Collins, Samuel A, Goutaki, Myrofora, Behan, Laura, Caudri, Daan, Dell, Sharon, Eber, Ernst, Escudier, Estelle, Hirst, Robert A, Hogg, Claire, Jorissen, Mark, Latzin, Philipp, Legendre, Marie, Leigh, Margaret W, Midulla, Fabio, Nielsen, Kim G, Omran, Heymut, Papon, Jean Francoi, Pohunek, Petr, Redfern, Beatrice, Rigau, David, Rindlisbacher, Bernhard, Santamaria, Francesca, Shoemark, Amelia, Snijders, Deborah, Tonia, Thomy, Titieni, Andrea, Walker, Woolf T, Werner, Claudiu, Bush, Andrew, Kuehni, Claudia E., University of Southampton, University Hospital Southampton NHS Foundation Trust, Università degli Studi di Padova = University of Padua (Unipd), Universität Bern [Bern] (UNIBE), Bern University Hospital [Berne] (Inselspital), The University of Western Australia (UWA), Erasmus University Rotterdam, University of Toronto, The Hospital for sick children [Toronto] (SickKids), Medical University Graz, Service de génétique et embryologie médicales [CHU Trousseau], CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Maladies génétiques d'expression pédiatrique [CHU Trousseau] (Inserm U933), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Trousseau [APHP], Leicester Royal Infirmary, University Hospitals Leicester, Royal Brompton Hospital, Imperial College London, University Hospitals Leuven [Leuven], University of North Carolina [Chapel Hill] (UNC), University of North Carolina System (UNC), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), Copenhagen University Hospital, University Hospital Münster - Universitaetsklinikum Muenster [Germany] (UKM), Service d’ORL et de chirurgie cervico-faciale [CHU Le Kremlin-Bicêtre], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Université Paris-Sud - Paris 11 (UP11), Charles University [Prague] (CU), PCD Family Support Group [Milton Keynes, UK] (PCDFSG), Iberoamerican Cochrane Center [Barcelona, Spain] (IA2C), Kartagener Syndrom und Primäre Ciliäre Dyskinesie e. V. [Steffisburg, Switzerland] (KSPC), 'Federico II' University of Naples Medical School, Couvet, Sandrine
المصدر: EUROPEAN RESPIRATORY JOURNAL
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
European Respiratory Journal
European Respiratory Journal, 2017, 49 (1), pp.1601090. ⟨10.1183/13993003.01090-2016⟩مصطلحات موضوعية: 0301 basic medicine, Pathology, [SDV]Life Sciences [q-bio], Respiratory System, primary ciliary dyskinesia, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, MESH: Delphi Technique, OUTER DYNEIN ARM, IDENTIFIES MUTATIONS, 0302 clinical medicine, OF-FUNCTION MUTATIONS, outer dynein arm, nasal nitric-oxide, of-function mutations, radial-spoke defects, mucociliary clearance disorder, multiple motile cilia, beat pattern, regulatory complex, identifies mutations, electron-microscopy, Medicine, guidelines, Medical diagnosis, 610 Medicine & health, MESH: Fluorescent Antibody Technique, Primary ciliary dyskinesia, ELECTRON-MICROSCOPY, REGULATORY COMPLEX, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, MESH: Genetic Testing, medicine.diagnostic_test, BEAT PATTERN, 11 Medical And Health Sciences, MESH: Review Literature as Topic, [SDV] Life Sciences [q-bio], MESH: Microscopy, Electron, Transmission, Ciliary Motility Disorders, Life Sciences & Biomedicine, rare disease, primary ciliary dyskinesia, guidelines, 360 Social problems & social services, Pulmonary and Respiratory Medicine, medicine.medical_specialty, MESH: Societies, Medical, rare disease, MUCOCILIARY CLEARANCE DISORDER, NASAL NITRIC-OXIDE, MULTIPLE MOTILE CILIA, 03 medical and health sciences, MESH: Cilia, MESH: Diagnosis, Differential, Intensive care medicine, Genetic testing, Science & Technology, MESH: Humans, business.industry, Gold standard (test), Guideline, medicine.disease, MESH: Microscopy, Video, 030104 developmental biology, 030228 respiratory system, RADIAL-SPOKE DEFECTS, MESH: Nitric Oxide, MESH: Kartagener Syndrome, [SDV.MHEP.PSR] Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, MESH: Europe, Outer dynein arm, Differential diagnosis, business, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
وصف الملف: text
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08484598efe3b20c9071d5ff7503a464
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المؤلفون: Vergoni, Bastien, Cornejo, Pierre-Jean, Gilleron, Jérôme, Dedjani, Mansour, Ceppo, Franck, Jacquel, Arnaud, Bouget, Gwennaelle, Ginet, Clémence, Gonzalez, Teresa, Maillet, Julie, Dhennin, Véronique, Verbanck, Marie, Auberger, Patrick, Froguel, Philippe, Tanti, Jean-François, Cormont, Mireille
المساهمون: Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (... - 2019) (UNS), Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Physiopathologie Cellulaire et Moléculaire de l'Obésité et du Diabète (Equipe 7), Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Nice Sophia Antipolis (... - 2019) (UNS), Mort cellulaire, différenciation et cancer (Equipe 2), Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-C3M - Centre Méditerranéen de Médecine Moléculaire, Hôpital l'Archet - CHU de Nice-Hôpital l'Archet - CHU de Nice, Nutrition, obésité et risque thrombotique (NORT), Aix Marseille Université (AMU)-Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), European Genomic Institute for Diabetes (EGID), Faculté de Médecine-Université de Lille, Droit et Santé, Génomique Intégrative et Modélisation des Maladies Métaboliques (EGID), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Department of Genomics of Common Disease [London, UK], Imperial College London-School of public health, The University of Hong Kong (HKU)-The University of Hong Kong (HKU), This work was supported by INSERM, the Université Côte d'Azur, and by grants from the European Foundation for the Study of Diabetes (EFSD/Lilly), SFD-Abbott, Aviesan/AstraZeneca (Diabetes and the Vessel Wall Injury Program), and the French National Research Agency (ANR) through 'Investments for the Future' Labex SIGNALIFE (grant ANR-11-LABX-0028-01). Light microscopy was performed at the C3M Imaging core facility (part of the Microscopy and Imaging platform Côte d’Azur IBISA). The Nikon A1R-FLIM microscope used for this study was funded thanks to Conseil Général Alpes-Maritimes ('Appel à Projets Santé') and by Région Provence-Alpes-Côte d'Azur (PACA) ('Appel à Projets Plateforme'). The UMR 8199 Genotyping and Expression platform (Lille, France) belongs to the 'Federation de Recherche' 3508 funded by Labex EGID (European Genomics Institute for Diabetes, ANR-10-LABX-46) and by the ANR Equipex 2010 session (ANR-10-EQPX-07-01, 'LIGAN-PM'). The LIGAN-PM Genomics platform (Lille, France) is also supported by the Fonds Européen de Développement Régional (FEDR) and the Region Nord-Pas-de-Calais-Picardie. B.V. and P.-J.C. were supported by the French Ministry of Education and Research. J.G. was supported by a fellowship (postdoctoral grant) from the 'Fondation pour la Recherche Médicale.' F.C. was supported by a fellowship from INSERM/Région PACA/FEDER (PhD grant) and by a grant from the Société Francophone du Diabète (SFD/Abbott). G.B. was supported by the Labex SIGNALIFE grant (ANR-11-LABX-0028-01). J.-F.T. is an investigator of the CNRS., The authors thank the animal facility staff for animal care and breeding, Damien Alcor, head of the Cell Imaging core facility (INSERM UMR 1065, C3M, Nice, France), and also Prof. Marino Zerial and Dr. Yannis Lalaiszidis (Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany) for the free access to the motion-tracking software developed in Prof. Zerial’s laboratory., ANR: 11-LABX-0028,SIGNALIFE,Réseau d'Innovation sur les Voies de Signalisation en Sciences de la Vie(2011), ANR-10-LABX-0046/10-LABX-0046,EGID,EGID Diabetes Pole(2010), ANR-10-EQPX-07-01 ,[LIGAN-PM],ANR Equipex 2010 session, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-C3M - Centre Méditerranéen de Médecine Moléculaire, Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283 (GI3M), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), ANR-11-LABX-0028,SIGNALIFE,Réseau d'Innovation sur les Voies de Signalisation en Sciences de la Vie(2011), ANR-10-LABX-0046,EGID,EGID Diabetes Pole(2010), ANR-10-EQPX-0007,LIGAN PM,Plate forme Lilloise de séquençage du génome humain pour une médecine personnalisée(2010), ANR-15-IDEX-0001,UCA JEDI,Idex UCA JEDI(2015), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (1965 - 2019) (UNS), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Européen de Génomique du Diabète - European Genomic Institute for Diabetes - FR 3508 (EGID), Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283 (EGENODIA (GI3M)), Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Cormont, Mireille, Centres d'excellences - Réseau d'Innovation sur les Voies de Signalisation en Sciences de la Vie - - SIGNALIFE2011 - ANR-11-LABX-0028 - LABX - VALID, EGID Diabetes Pole - - EGID2010 - ANR-10-LABX-0046 - LABX - VALID, Plate forme Lilloise de séquençage du génome humain pour une médecine personnalisée - - LIGAN PM2010 - ANR-10-EQPX-0007 - EQPX - VALID, Idex UCA JEDI - - UCA JEDI2015 - ANR-15-IDEX-0001 - IDEX - VALID
المصدر: Diabetes
Diabetes, American Diabetes Association, 2016, 65 (10), pp.3062-3074. ⟨10.2337/db16-0014⟩
Diabetes, 2016, 65 (10), pp.3062-3074. ⟨10.2337/db16-0014⟩مصطلحات موضوعية: [SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, MESH: Signal Transduction/physiology, MESH: Humans, MESH: DNA Damage/genetics, MESH: Flow Cytometry, MESH: Chemotaxis/physiology, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, MESH: Reactive Oxygen Species/metabolism, MESH: 3T3-L1 Cells, MESH: Chemotaxis/genetics, [SDV.AEN] Life Sciences [q-bio]/Food and Nutrition, MESH: Glucose Transporter Type 4/metabolism, MESH: Glucose Transporter Type 4/genetics, MESH: Telomere/genetics, MESH: Tumor Suppressor Protein p53/genetics, MESH: DNA Damage/physiology, MESH: Blotting, Western, MESH: RAW 264.7 Cells, MESH: Animals, MESH: Signal Transduction/genetics, MESH: Tumor Suppressor Protein p53/metabolism, MESH: Adipocytes/metabolism, MESH: Fluorescent Antibody Technique, MESH: Mice, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9c8b20bbd82ba41801276eb174839a70
https://www.hal.inserm.fr/inserm-01345698 -
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المؤلفون: Regina P. Markus, Cathy Vaillancourt, Lucas Sagrillo-Fagundes, Eugania Maria Assuncao Salustiano, Rodrigo Ruano
المساهمون: Institut Armand Frappier (INRS-IAF), Réseau International des Instituts Pasteur (RIIP)-Institut National de la Recherche Scientifique [Québec] (INRS), Université du Québec à Montréal = University of Québec in Montréal (UQAM), Mayo Clinic [Rochester], University of São Paulo (USP), upported by grants from the Natural Sciences and Engineering Research Council of Canada (NSERC) (no. 262011‐2009) to CV as well as by fellowship to EMAS from the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) and from the Programme de bourses d'excellence pour étudiants étrangers du Ministère de l’Éducation, de l'Enseignement superieurs et de la recherche (MEESR)‐Fonds de recherché du Québec‐Nature et technologies (FRQNT), by studentship awards to LSF from the Ministère de l’Éducation, du loisir et du sport (MELS), du Québec‐Fonds de recherché du Québec‐Nature e technologies (FRQNT) and also studentship from Fondation Armand Frappier, and from Fondation Armand Frappier and Réseau Québécois en reproduction (RQR)‐NSERC‐Collaborative Research., The authors thank women who donated their placentas for this study. We would like to thank Laetitia Laurent, Ph.D., for her technical support in the laboratory
المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Journal of Pineal Research
Journal of Pineal Research, Wiley, 2018, 65 (4), pp.e12520. ⟨10.1111/jpi.12520⟩مصطلحات موضوعية: 0301 basic medicine, MESH: Melatonin/metabolism, [SDV]Life Sciences [q-bio], Placenta, syncytiotrophoblast, TNF, Fluorescent Antibody Technique, Chorionic Gonadotropin, MESH: Pregnancy, Endocrinology, interleukin (IL)-6, Pregnancy, PLACENTA, Phosphorylation, MESH: Fluorescent Antibody Technique, Cells, Cultured, Melatonin, MESH: Immunoblotting, Chemistry, NF-kappa B, MESH: Trophoblasts/metabolism, Cell Hypoxia, Interleukin-10, Trophoblasts, medicine.anatomical_structure, IL-10, embryonic structures, Female, Tumor necrosis factor alpha, MESH: NF-kappa B/metabolism, medicine.symptom, hormones, hormone substitutes, and hormone antagonists, MESH: Cells, Cultured, medicine.drug, medicine.medical_specialty, MESH: Inflammation/metabolism, Immunoblotting, Inflammation, arylalkylamine N-acetyltransferase (AANAT), villous cytotrophoblasts, 03 medical and health sciences, MESH: Chorionic Gonadotropin/metabolism, Syncytiotrophoblast, Internal medicine, Autophagy, medicine, Humans, MESH: Interleukin-10/metabolism, MESH: Humans, MESH: Phosphorylation, L-Lactate Dehydrogenase, Interleukin-6, MESH: Interleukin-6/metabolism, MESH: Autophagy/physiology, Trophoblast, MESH: Cell Hypoxia/physiology, MESH: Placenta/cytology, 030104 developmental biology, MESH: L-Lactate Dehydrogenase/metabolism, Apoptosis, MESH: Female, NFκB
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9
المؤلفون: Nathalie Daval, Mohamed Kasbari, Nicolas Keck, Laurent Guillaumot, Céline Marchal, Christophe Ravel, Thomas Hüe
المساهمون: Direction des Affaires Vétérinaires, Alimentaires et Rurales (DAVAR), Institut Pasteur de Nouvelle-Calédonie, Réseau International des Instituts Pasteur (RIIP), Institut Agronomique Néo-Calédonien (IAC), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Centre National de Référence des Leishmanioses [CHRU Montpellier] (CNR-L), Université de Montpellier (UM)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Laboratoire Départemental Vétérinaire de l'Hérault, Conseil Général de l'Hérault, Laboratoire de santé animale, sites de Maisons-Alfort et de Dozulé, Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES)
المصدر: Parasites & Vectors
Parasites and Vectors
Parasites and Vectors, BioMed Central, 2016, 9 (1), pp.108. ⟨10.1186/s13071-016-1388-6⟩مصطلحات موضوعية: MESH: Histocytochemistry, Entomology, Veterinary medicine, MESH: Leishmaniasis, Importation risk, 0403 veterinary science, MESH: Dogs, MESH: Communicable Disease Control, 0302 clinical medicine, Zoonoses, Canine leishmaniasis, MESH: Animals, Dog Diseases, Leishmania infantum, Fluorescent Antibody Technique, Indirect, Leishmaniasis, Transmission (medicine), MESH: Real-Time Polymerase Chain Reaction, Histocytochemistry, 04 agricultural and veterinary sciences, MESH: Leishmania infantum, 3. Good health, Isoenzymes, Infectious Diseases, MESH: Isoenzymes, MESH: Zoonoses, Non-vectorial transmission, 040301 veterinary sciences, MESH: Dog Diseases, 030231 tropical medicine, Zoology, Biology, MESH: Disease Transmission, Infectious, Real-Time Polymerase Chain Reaction, 03 medical and health sciences, Dogs, New Caledonia, Transplacental and venereal transmission routes, medicine, Disease Transmission, Infectious, MESH: Fluorescent Antibody Technique, Indirect, Animals, [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, Direct fluorescent antibody, [SDV.BA.MVSA]Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health, Research, medicine.disease, biology.organism_classification, MESH: New Caledonia, Parasitology, Vector (epidemiology), Communicable Disease Control, Phlebotomine sandflies, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
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10
المؤلفون: B. Mograbi, Juliana Tournebize, B. Foliguet, I. Aboukhamis, Philippe Maincent, Housam Eidi, Olivier Joubert, A. Le Faou, Bertrand H. Rihn, C. Némos, Stéphanie Grandemange
المساهمون: Cibles thérapeutiques, formulation et expertise pré-clinique du médicament (CITHEFOR), Université de Lorraine (UL), Signalisation, Génomique et Recherche Translationnelle en Oncologie (SIGRETO), Université Henri Poincaré - Nancy 1 (UHP), Infection bactérienne, inflammation, et carcinogenèse digestive, Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-IFR50-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), Service de Foetopathologie et placentologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)
المصدر: International Journal of Pharmaceutics
International Journal of Pharmaceutics, Elsevier, 2012, 422 (1-2), pp.495-503. ⟨10.1016/j.ijpharm.2011.11.020⟩مصطلحات موضوعية: MESH: Macrophages, Alveolar, Chemistry, Pharmaceutical, Fluorescent Antibody Technique, Pharmaceutical Science, 02 engineering and technology, MESH: Reverse Transcriptase Polymerase Chain Reaction, Chemical Precipitation, Nanotechnology, MESH: Animals, MESH: Nanotechnology, MESH: Fluorescent Antibody Technique, Oligonucleotide Array Sequence Analysis, MESH: Glutathione, MESH: Technology, Pharmaceutical, Drug Carriers, 0303 health sciences, medicine.diagnostic_test, Reverse Transcriptase Polymerase Chain Reaction, Chemistry, MESH: Reactive Oxygen Species, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, 021001 nanoscience & nanotechnology, Glutathione, MESH: Gene Expression Regulation, Endocytosis, Mitochondria, 3. Good health, Blot, MESH: Drug Carriers, MESH: Endocytosis, Drug delivery, MESH: Microscopy, Electron, Transmission, 0210 nano-technology, Drug carrier, MESH: Chemical Precipitation, MESH: Microscopy, Electron, Scanning, MESH: Rats, MESH: Mitochondria, Drug Compounding, Blotting, Western, Cell Line, MESH: Chemistry, Pharmaceutical, 03 medical and health sciences, Microscopy, Electron, Transmission, Polymethacrylic Acids, Western blot, Macrophages, Alveolar, Autophagy, medicine, Animals, Technology, Pharmaceutical, MESH: Autophagy, MESH: Blotting, Western, MESH: Particle Size, Particle Size, 030304 developmental biology, MESH: Polymethacrylic Acids, Molecular biology, Rats, MESH: Cell Line, Gene Expression Regulation, Cell culture, Apoptosis, MESH: Oligonucleotide Array Sequence Analysis, MESH: Drug Compounding, Microscopy, Electron, Scanning, Biophysics, Nanoparticles, Reactive Oxygen Species, MESH: Nanoparticles
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