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المؤلفون: Rozier, Pauline, Maumus, Marie, Maria, Alexandre Thibault Jacques, Toupet, Karine, Jorgensen, Christian, Guilpain, Philippe, Noël, Danièle
المساهمون: Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Service de Rhumatologie [CHRU Montpellier], Salvy-Córdoba, Nathalie
المصدر: Cells
Volume 10
Issue 10
Cells, Vol 10, Iss 2727, p 2727 (2021)
Cells, MDPI, 2021, 10 (10), pp.2727. ⟨10.3390/cells10102727⟩مصطلحات موضوعية: MESH: Interferon-gamma, QH301-705.5, Pulmonary Fibrosis, Anti-Inflammatory Agents, exosomes, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, MESH: Scleroderma, Systemic, MESH: Immunosuppression Therapy, Article, Interferon-gamma, MESH: Skin, MESH: Mice, Inbred C57BL, MESH: Up-Regulation, Animals, MESH: Animals, scleroderma, MESH: Extracellular Vesicles, Biology (General), Skin, Immunosuppression Therapy, [SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, therapy, Scleroderma, Systemic, MESH: Pulmonary Fibrosis, Mesenchymal Stem Cells, [SDV.IMM.IMM]Life Sciences [q-bio]/Immunology/Immunotherapy, Up-Regulation, Mice, Inbred C57BL, MicroRNAs, MESH: Mesenchymal Stem Cells, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, MESH: Anti-Inflammatory Agents, mesenchymal stromal cell, [SDV.MHEP.PSR] Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, [SDV.IMM.IMM] Life Sciences [q-bio]/Immunology/Immunotherapy, extracellular vesicles, MESH: MicroRNAs, microvesicles
وصف الملف: application/pdf
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المؤلفون: Martial Marbouty, Stefano Cairo, Christine Neuveut, Romain Koszul, Agnès Thierry, Gianna Aurora Palumbo, Marc Lavigne, Shogofa Mortaza, Axel Cournac, Pierrick Moreau
المساهمون: Hépacivirus et Immunité innée, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Régulation spatiale des Génomes - Spatial Regulation of Genomes, XenTech [Évry], Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Département de Virologie - Department of Virology, Institut Pasteur [Paris], This work was supported by funding to C.N. from the Agence Nationale de la Recherche sur le Sida et les Hépatites Virales (ANRS) and Fondation pour la Recherche sur le Cancer (ARC). This research was also supported by funding to R.K. from the European Research Council under the 7th and H2020 Framework Program (FP7/2007-2013, ERC grant agreement 260822 and H2020 ERC grant agreement DLV-771813), and from Agence Nationale pour la Recherche (MeioRec ANR-13-BSV6-0012). P.M. was supported by ANRS and Institut Carnot. This study makes use of data generated by the ENCODE Consortium and the ENCODE production laboratories., We thank C. Seeger and S. Urban for kindly providing cell lines used in this study. We thank the UTechS PBI (Imagopole)-DTPS/C2RT, part of the France-BioImaging infrastructure network supported by the ANR (ANR-10-INSB-04, Investments for theFuture), for the use of the Zeiss widefield apotome microscope., ANR-13-BSV6-0012,MeioRec,Dynamique chromosomique et recombinaison au cours de la méiose(2013), European Project: 260822,EC:FP7:ERC,ERC-2010-StG_20091118,DICIG(2011), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut Pasteur [Paris] (IP), THIERRY, AGNES, Blanc 2013 - Dynamique chromosomique et recombinaison au cours de la méiose - - MeioRec2013 - ANR-13-BSV6-0012 - Blanc 2013 - VALID, Dynamic Interplay between Eukaryotic Chromosomes: Impact on Genome Stability - DICIG - - EC:FP7:ERC2011-06-01 - 2017-05-31 - 260822 - VALID
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.4268. ⟨10.1038/s41467-018-06739-4⟩
Nature Communications, 2018, 9 (1), pp.4268. ⟨10.1038/s41467-018-06739-4⟩مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, viruses, General Physics and Astronomy, MESH: Base Sequence, Genome, chemistry.chemical_compound, MESH: Chromatin / metabolism, 0302 clinical medicine, Transcription (biology), Adenovirus, Viral Regulatory and Accessory Proteins, lcsh:Science, [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Multidisciplinary, Virus–host interactions, Hep G2 Cells, MESH: Gene Expression Regulation, Chromatin, 3. Good health, Cell biology, Up-Regulation, CpG site, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, MESH: Transcription Initiation Site, Transcription Initiation Site, Plasmids, Hepatitis B virus, Science, MESH: Hep G2 Cells, Biology, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, MESH: Plasmids / metabolism, MESH: Genome, Human, MESH: Up-Regulation / genetics, Humans, MESH: DNA, Viral / genetics, Enhancer, Gene, Transcription factor, MESH: Humans, Base Sequence, Genome, Human, MESH: Transcription, Genetic, MESH: Models, Biological, General Chemistry, MESH: Hepatitis B virus / physiology, MESH: CpG Islands / genetics, MESH: Hepatocytes / virology, MESH: Trans-Activators / metabolism, 030104 developmental biology, chemistry, Gene Expression Regulation, DNA, Viral, Hepatocytes, Trans-Activators, CpG Islands, lcsh:Q, 030217 neurology & neurosurgery, DNA
وصف الملف: application/pdf
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المؤلفون: Chantal Etievant, Audrey Delmas, Paola B. Arimondo, Arnaud Pillon, Gilles Favre, Joëlle Riond, Jörg Tost, Arnaud Carrier, Florence Busato, Cécile Desjobert, Antoine Daunay, Diego M. Marzese
المساهمون: Pharmacochimie de la Régulation Epigénétique du Cancer (ETaC), PIERRE FABRE-Centre National de la Recherche Scientifique (CNRS), Centre de biologie du développement (CBD), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Centre d'Etude du Polymorphisme Humain (CEPH), Université Paris Diderot - Paris 7 (UPD7)-Institut Universitaire d'Hématologie (IUH), Université Paris Diderot - Paris 7 (UPD7)-Fondation Jean Dausset, Centre National de Génotypage (CNG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Laboratoires Pierre Fabre, Laboratoire d'Epigénétique et d'Environnement [Evry] (CNG - CEA), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de Genotypage-Institut de Génomique [Evry], Centre de Recherches en Cancérologie de Toulouse (CRCT), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS), PIERRE FABRE-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Centre de Biologie Intégrative (CBI), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), John Wayne Cancer Institute [Santa Monica, CA, USA], Chimie biologique épigénétique - Epigenetic Chemical Biology (EpiCBio), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), This work was supported to P.B.A. by Centre National de la Recherche Scientifique (CNRS) [ATIP], Région Midi Pyrenées [Equipe d’Excellence and FEDER CNRS/Région Midi Pyrenées], Fondation InNaBioSanté, and PlanCancer2014 (N°EPIG201401)., Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre de Biologie Intégrative (CBI), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Fondation Jean Dausset-Institut Universitaire d'Hématologie (IUH), Université Paris Diderot - Paris 7 (UPD7)-Université Paris Diderot - Paris 7 (UPD7), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Centre de Biologie Intégrative (CBI), Riond, Joelle
المصدر: Clinical Epigenetics
Clinical Epigenetics, BioMed Central, 2019, 11 (1), pp.9. ⟨10.1186/s13148-018-0600-2⟩
Clinical Epigenetics, 2019, 11 (1), pp.9. ⟨10.1186/s13148-018-0600-2⟩
Clinical Epigenetics, Vol 11, Iss 1, Pp 1-14 (2019)مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, [SDV]Life Sciences [q-bio], lcsh:Medicine, MESH: Spheroids, Cellular, Transcriptome, Mice, chemistry.chemical_compound, 0302 clinical medicine, MESH: DNA Methylation, MESH: Up-Regulation, MESH: Sequence Analysis, RNA, Gene Regulatory Networks, MESH: Animals, Promoter Regions, Genetic, Melanoma, Genetics (clinical), MESH: Gene Regulatory Networks, DNA methylation, microRNA, MESH: Gene Expression Regulation, Neoplastic, Up-Regulation, 3. Good health, Gene Expression Regulation, Neoplastic, [SDV] Life Sciences [q-bio], MESH: Cell Survival, 030220 oncology & carcinogenesis, Female, Deoxycytidine, Epigenetics, MESH: Cell Line, Tumor, lcsh:QH426-470, Cell Survival, MESH: Melanoma, education, Biology, Decitabine, 03 medical and health sciences, MESH: Gene Expression Profiling, In vivo, Cell Line, Tumor, Spheroids, Cellular, MESH: Promoter Regions, Genetic, Genetics, medicine, Animals, Humans, Neoplasm Invasiveness, Molecular Biology, MESH: Mice, neoplasms, MESH: Humans, MESH: Decitabine, Sequence Analysis, RNA, Research, Gene Expression Profiling, lcsh:R, MESH: Neoplasm Invasiveness, medicine.disease, Demethylating agent, MESH: Lung Neoplasms, lcsh:Genetics, MicroRNAs, 030104 developmental biology, chemistry, Cancer research, Melanoma aggressiveness, MESH: Female, MESH: MicroRNAs, Neoplasm Transplantation, MESH: Neoplasm Transplantation, Developmental Biology
وصف الملف: application/pdf
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المؤلفون: Mariette Matondo, Pascale Cossart, Filipe Carvalho, Fabrizia Stavru, Anna Spier, T. Chaze
المساهمون: Interactions Bactéries-Cellules (UIBC), Institut National de la Recherche Agronomique (INRA)-Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris Diderot - Paris 7 (UPD7), Spectrométrie de Masse pour la Biologie – Mass Spectrometry for Biology (UTechS MSBio), Institut Pasteur [Paris]-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), This study was supported by grants to P.C. from the European Research Council (H2020-ERC-2014-409ADG 670823-BacCellEpi), the Agence Nationale de la Recherche (ANR) and the French Government’s 'Investissements d’Avenir' program Laboratoires d’Excellence 'Integrative Biology of Emerging Infectious Diseases' (LabEx IBEID, ANR-10-LABX-62-IBEID). A.S. was supported by a BioSPC doctoral fellowship from the Université Paris Diderot. P.C. is a Senior International Research Scholar of the Howard Hughes Medical Institute. F.S. is a CNRS permanent researcher, We thank current and past lab members for helpful discussions, Francis Impens and Evy Timmerman (VIB Proteomics Core, University of Ghent, Belgium) for training and assistance with proteomic analyses, and Alessandro Pagliuso for critical reading of the manuscript, ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), European Project: 670823,H2020,ERC-2014-ADG,BacCellEpi(2015), Centre National de la Recherche Scientifique (CNRS)-Centre de Ressources et de Recherche Technologique - Center for Technological Resources and Research (C2RT), Institut Pasteur [Paris]-Institut Pasteur [Paris], ANR-10-LABX-62-IBEID,IBEID,Laboratoire d'Excellence 'Integrative Biology of Emerging Infectious Diseases'(2010), Institut National de la Recherche Agronomique (INRA)-Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris] (IP)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Stavru, Fabrizia, Integrative Biology of Emerging Infectious Diseases - - IBEID2010 - ANR-10-LABX-0062 - LABX - VALID, Bacterial, cellular and epigenetic factors that control enteropathogenicity - BacCellEpi - - H20202015-10-01 - 2018-09-30 - 670823 - VALID, Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur [Paris]-Institut National de la Recherche Agronomique (INRA)
المصدر: mBio
mBio, American Society for Microbiology, 2020, 11 (1), ⟨10.1128/mBio.03171-19⟩
mBio, 2020, 11 (1), ⟨10.1128/mBio.03171-19⟩مصطلحات موضوعية: Mic10, MESH: HCT116 Cells, MESH: Mitochondria, [SDV]Life Sciences [q-bio], [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Mitochondrion, Biology, MESH: Listeria monocytogenes, medicine.disease_cause, 03 medical and health sciences, proteomics, 0302 clinical medicine, Listeria monocytogenes, Organelle, MESH: Up-Regulation, medicine, Inner mitochondrial membrane, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, [SDV.MP] Life Sciences [q-bio]/Microbiology and Parasitology, 030304 developmental biology, 0303 health sciences, MESH: Humans, MICOS complex, mitochondrial fission, MESH: Proteomics, Listeriolysin O, MESH: Mitochondrial Proteins, MESH: Mitochondrial Dynamics, Cell biology, [SDV] Life Sciences [q-bio], [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Mitochondrial fission, MESH: Membrane Proteins, 030217 neurology & neurosurgery, Intracellular
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e9e3457ca897166d9cfa7bbc722cc9
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المؤلفون: Narimane Al Kattani, Antoine Kimmoun, Chaojie Wei, Nicolas Dessales, Pierre-Yves Marie, Julie Delemazure, Bruno Levy, Huguette Louis, Khodor Issa
المساهمون: Défaillance Cardiovasculaire Aiguë et Chronique (DCAC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL)
المصدر: Critical Care Medicine
Critical Care Medicine, Lippincott, Williams & Wilkins, 2015, 43 (9), pp.e332-e340. ⟨10.1097/CCM.0000000000001078⟩مصطلحات موضوعية: Male, MESH: NF-kappa B, Adrenergic, Critical Care and Intensive Care Medicine, Propanolamines, Norepinephrine, MESH: Reverse Transcriptase Polymerase Chain Reaction, MESH: Up-Regulation, Vasoconstrictor Agents, MESH: Animals, Reverse Transcriptase Polymerase Chain Reaction, NF-kappa B, Esmolol, Adrenergic beta-1 Receptor Antagonists, Shock, Septic, Up-Regulation, 3. Good health, MESH: Adrenergic beta-1 Receptor Antagonists, Shock (circulatory), Cardiology, Drug Therapy, Combination, Inflammation Mediators, medicine.symptom, MESH: Nitric Oxide Synthase Type III, medicine.drug, Cardiac function curve, MESH: Hemodynamics, medicine.medical_specialty, MESH: Rats, Nitric Oxide Synthase Type III, MESH: Shock, Septic, MESH: Inflammation Mediators, Sepsis, MESH: Vasoconstrictor Agents, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, In vivo, MESH: Norepinephrine, Receptors, Adrenergic, alpha-1, Internal medicine, medicine, Animals, Rats, Wistar, MESH: Propanolamines, Septic shock, business.industry, Hemodynamics, MESH: Rats, Wistar, medicine.disease, MESH: Male, Rats, MESH: Drug Therapy, Combination, Disease Models, Animal, MESH: Disease Models, Animal, business, MESH: Receptors, Adrenergic, alpha-1, Ex vivo
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49109269aa1353a3ee195f382c70cbcf
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المؤلفون: Olivier Alibeu, Lam Son Nguyen, Julien Fregeac, Eleonora Aronica, Christine Bole-Feysot, Anand Iyer, Patrick Nitschké, Laurence Colleaux, Jasper J. Anink, Nicolas Cagnard
المساهمون: Pathology, ANS - Cellular & Molecular Mechanisms, APH - Aging & Later Life, APH - Mental Health, Imagine - Institut des maladies génétiques (IMAGINE - U1163), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Necker - Enfants Malades [AP-HP], Université Paris Descartes - Paris 5 (UPD5), Université Sorbonne Paris Cité (USPC), Genome Analysis, Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)
المصدر: Molecular Autism
Molecular autism, 9(1):38. BioMed Central
Molecular Autism, BioMed Central, 2019, 9, pp.38. ⟨10.1186/s13229-018-0219-3⟩
Molecular Autism, Vol 9, Iss 1, Pp 1-12 (2018)مصطلحات موضوعية: 0301 basic medicine, MESH: Neural Stem Cells, Male, Human neural stem cell, Autism Spectrum Disorder, lcsh:RC346-429, Transcriptome, Neural Stem Cells, MESH: Child, MESH: Up-Regulation, Child, MESH: Autism Spectrum Disorder, Neocortex, microRNA, Human brain, Autism spectrum disorders, Neural stem cell, Temporal Lobe, Up-Regulation, Psychiatry and Mental health, medicine.anatomical_structure, Female, Cell type, Neurite, Neurogenesis, Biology, Cell Line, 03 medical and health sciences, Developmental Neuroscience, Downregulation and upregulation, medicine, MESH: Temporal Lobe, Humans, Cell Lineage, Molecular Biology, lcsh:Neurology. Diseases of the nervous system, MESH: Humans, Research, MESH: Cell Lineage, MESH: Male, MESH: Cell Line, MESH: Neurogenesis, MicroRNAs, 030104 developmental biology, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, Neuroscience, MESH: Female, MESH: MicroRNAs, Developmental Biology
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المؤلفون: F. Valentin, Juliette Mazereeuw-Hautier, Nathalie Jonca, Guy Serre, Anne Huchenq, M. Pichery, Vinzenz Oji, Sarra Zaafouri
المساهمون: CARBILLET, Véronique, Unité différenciation épidermique et auto-immunité rhumatoïde (UDEAR), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), University Hospital Münster - Universitaetsklinikum Muenster [Germany] (UKM), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), CHU Toulouse [Toulouse]
المصدر: Journal of Investigative Dermatology
Journal of Investigative Dermatology, 2018, 138 (6), pp.1431-1435. ⟨10.1016/j.jid.2017.12.020⟩
Journal of Investigative Dermatology, Nature Publishing Group, 2018, 138 (6), pp.1431-1435. ⟨10.1016/j.jid.2017.12.020⟩مصطلحات موضوعية: 0301 basic medicine, Disease, Biochemistry, MESH: Mice, Knockout, MESH: Down-Regulation, MESH: Dermatitis, Exfoliative / pathology, Transcriptome, Mice, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Deficient mouse, MESH: Up-Regulation, MESH: Animals, MESH: Skin Diseases, Genetic / pathology, ComputingMilieux_MISCELLANEOUS, Mice, Knockout, MESH: Dermatitis, Exfoliative / genetics, Skin Diseases, Genetic, MESH: Epidermis / pathology, MESH: Skin Diseases, Genetic / genetics, Up-Regulation, 3. Good health, MESH: Glycoproteins / genetics, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Intercellular Signaling Peptides and Proteins, Female, Dermatitis, Exfoliative, Down-Regulation, Dermatology, Computational biology, MESH: Transcriptome / genetics, Biology, 03 medical and health sciences, MESH: Gene Expression Profiling, Text mining, Downregulation and upregulation, Animals, Humans, MESH: Intercellular Signaling Peptides and Proteins, Molecular Biology, Gene, MESH: Mice, Glycoproteins, MESH: Humans, business.industry, Gene Expression Profiling, Cell Biology, Fold change, Gene expression profiling, Disease Models, Animal, 030104 developmental biology, Epidermis, MESH: Disease Models, Animal, business, MESH: Female
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e201792c5cf12a7e6df164ddfb8a7a5
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المؤلفون: Frederic A. Carvalho, Agathe Gelot, Nicolas Barnich, Amandine Lashermes, Ludivine Boudieu, Julie Barbier, Benoit Sion, Denis Ardid
المساهمون: Neuro-Dol (Neuro-Dol), Université d'Auvergne - Clermont-Ferrand I (UdA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire d'endocrinologie moléculaire, Hôpital de la Conception [CHU - APHM] (LA CONCEPTION), Pharmacologie fondamentale et clinique de la douleur, Université d'Auvergne - Clermont-Ferrand I (UdA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université d'Auvergne - Clermont-Ferrand I (UdA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université d'Auvergne - Clermont-Ferrand I (UdA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne), Hôpital de la Conception [CHU - APHM] (LA CONCEPTION ), Université d'Auvergne - Clermont-Ferrand I (UdA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université d'Auvergne - Clermont-Ferrand I (UdA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte - Clermont Auvergne (M2iSH), Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne (UCA)-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne), Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne)-Institut National de la Recherche Agronomique (INRA)
المصدر: Gut microbes
Gut microbes, Taylor & Francis, 2017, 9 (1), pp.26-37. ⟨10.1080/19490976.2017.1361091⟩
Gut microbes, 2017, 9 (1), pp.26-37. ⟨10.1080/19490976.2017.1361091⟩مصطلحات موضوعية: Male, 0301 basic medicine, MESH: Inflammation, MESH: Receptors, Purinergic P2X, Inflammatory bowel disease, Mice, Adherent invasive E. coli, 0302 clinical medicine, Crohn Disease, MESH: Colitis, MESH: Up-Regulation, MESH: Animals, Intestinal Mucosa, Receptor, MESH: Antigens, CD, Escherichia coli Infections, Irritable bowel syndrome, 2. Zero hunger, colonic hypersensitivity, MESH: Escherichia coli, Gastroenterology, Colitis, Up-Regulation, 3. Good health, Infectious Diseases, medicine.anatomical_structure, Receptors, Purinergic P2X, MESH: Permeability, MESH: Intestinal Mucosa, MESH: Cell Adhesion Molecules, Female, 030211 gastroenterology & hepatology, visceral pain, medicine.symptom, Microbiology (medical), Genetically modified mouse, Colon, MESH: Mice, Transgenic, Mice, Transgenic, Inflammation, Ileum, GPI-Linked Proteins, Microbiology, Permeability, 03 medical and health sciences, Antigens, CD, MESH: Mice, Inbred C57BL, Escherichia coli, medicine, Animals, MESH: Colon, MESH: Mice, MESH: Escherichia coli Infections, Intestinal permeability, MESH: Crohn Disease, business.industry, intestinal permeability, P2X receptors, Visceral pain, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, medicine.disease, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, MESH: Male, Mice, Inbred C57BL, 030104 developmental biology, MESH: Ileum, Research Paper/Report, Immunology, MESH: GPI-Linked Proteins, business, Cell Adhesion Molecules, MESH: Female
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المؤلفون: Guillaume Laval, Luis B. Barreiro, Yohann Nédélec, Erwin Schurr, Jeremy Manry, Vu Hong Thai, Vinicius M. Fava, Nguyen Van Thuc, Aurélie Cobat, Marianna Orlova
المساهمون: McGill University = Université McGill [Montréal, Canada], CHU Sainte Justine [Montréal], CRSN/Faculté de médecine Université de Montréal, Génétique Humaine des Maladies Infectieuses (Inserm U980), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Imagine - Institut des maladies génétiques (IMAGINE - U1163), Hospital for Tropical Diseases - HTD [Ho Chi Minh City, Vietnam], Génétique Evolutive Humaine - Human Evolutionary Genetics, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Centre de Bioinformatique, Biostatistique et Biologie Intégrative (C3BI), Université de Montréal (UdeM), This work was supported by a Foundation grant from the Canadian Institutes of Health Research (CIHR FDN – 14332) to ES. This research was supported through resource allocation in the Guillimin high performance computing cluster by Compute Canada (www.computecanada.ca) and Calcul Québec (http://www.calculquebec.ca/) (jrt-675-01). JM was supported by a CIHR fellowship (MFE-127384) and in part by a grant from the Laboratory of Excellence Integrative Biology of Emerging Infectious Diseases (LabEx IBEID: http://www.pasteur.fr/labex/ibeid), We thank all leprosy patients who participated in this study. We thank the members of the Schurr lab and the members of the laboratory for Human Genetics of Infectious Diseases in Paris for useful discussions and suggestions on this work. We thank the members of the Human Evolutionary Genetics laboratory, Institut Pasteur, Paris, and especially Maxime Rotival for useful discussions and suggestions on this work., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), Bidault, Floran, Integrative Biology of Emerging Infectious Diseases - - IBEID2010 - ANR-10-LABX-0062 - LABX - VALID, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)
المصدر: PLoS Genetics
PLoS Genetics, Public Library of Science, 2017, 13 (8), pp.e1006952. ⟨10.1371/journal.pgen.1006952⟩
PLoS Genetics, 2017, 13 (8), pp.e1006952. ⟨10.1371/journal.pgen.1006952⟩
PLoS Genetics, Vol 13, Iss 8, p e1006952 (2017)مصطلحات موضوعية: 0301 basic medicine, Bacterial Diseases, Cancer Research, Genome-wide association study, Genome-wide association studies, MESH: Down-Regulation, 0302 clinical medicine, Human genetics, Gene expression, Medicine and Health Sciences, MESH: Up-Regulation, Pathogen, Mycobacterium leprae, Genetics of disease, Genetics (clinical), MESH: Genetic Association Studies, Genetics, Principal Component Analysis, MESH: Polymorphism, Single Nucleotide, MESH: Genetic Predisposition to Disease, Genomics, 3. Good health, Up-Regulation, Actinobacteria, RNA, Bacterial, Infectious Diseases, Host-Pathogen Interactions, Gene ontologies, [SDV.IMM]Life Sciences [q-bio]/Immunology, Leprosy, MESH: RNA, Bacterial, Research Article, Neglected Tropical Diseases, lcsh:QH426-470, [SDV.IMM] Life Sciences [q-bio]/Immunology, Quantitative Trait Loci, Immunology, Down-Regulation, [SDV.GEN.GH] Life Sciences [q-bio]/Genetics/Human genetics, Biology, Polymorphism, Single Nucleotide, 03 medical and health sciences, Immune system, medicine, Humans, Genetic Predisposition to Disease, Immune response, Molecular Biology, Gene, Ecology, Evolution, Behavior and Systematics, Genetic Association Studies, MESH: Principal Component Analysis, Antigens, Bacterial, MESH: Humans, Bacteria, MESH: Host-Pathogen Interactions, Organisms, Biology and Life Sciences, Computational Biology, medicine.disease, biology.organism_classification, Tropical Diseases, Genome Analysis, MESH: Quantitative Trait Loci, MESH: Leprosy, lcsh:Genetics, 030104 developmental biology, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, Expression quantitative trait loci, MESH: Mycobacterium leprae, 030217 neurology & neurosurgery, MESH: Antigens, Bacterial
وصف الملف: application/pdf
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المؤلفون: Kint, Nicolas, Janoir, Claire, Monot, Marc, Hoys, Sandra, Soutourina, Olga, Dupuy, Bruno, Martin-Verstraete, Isabelle
المساهمون: Pathogénèse des Bactéries Anaérobies / Pathogenesis of Bacterial Anaerobes (PBA (U-Pasteur_6)), Institut Pasteur [Paris]-Université Paris Diderot - Paris 7 (UPD7), Université Paris Diderot - Paris 7 (UPD7), Bactéries, Pathogènes et Santé (UBaPS), Faculté de Pharmacie, Université Paris-Sud - Paris 11 (UP11)-Université Paris-Sud - Paris 11 (UP11), This work was funded by the Institut Pasteur and the University Paris 7., We are thankful to Thomas Dubois and Al Claiborne for helpful discussions and to Jovana Mihajlovic and Jean-Marc Ghigo for their help with oxygen assays., Institut Pasteur [Paris] (IP)-Université Paris Diderot - Paris 7 (UPD7), Université Paris-Sud - Paris 11 (UP11)-Université Paris-Saclay-Université Paris-Sud - Paris 11 (UP11)-Université Paris-Saclay
المصدر: Environmental Microbiology
Environmental Microbiology, Society for Applied Microbiology and Wiley-Blackwell, 2017, Special Issue on Pathogen and Antibiotic Resistance Ecology 19 (5), pp.1933-1958. ⟨10.1111/1462-2920.13696⟩
Environmental Microbiology, 2017, Special Issue on Pathogen and Antibiotic Resistance Ecology 19 (5), pp.1933-1958. ⟨10.1111/1462-2920.13696⟩
Environmental Microbiology, Wiley-Blackwell, 2017, Special Issue on Pathogen and Antibiotic Resistance Ecology 19 (5), pp.1933-1958. ⟨10.1111/1462-2920.13696⟩مصطلحات موضوعية: MESH: DNA Repair, MESH: Gene Expression Regulation, Bacterial, MESH: Oxidative Stress, MESH: Sigma Factor, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, MESH: Drug Resistance, Multiple, Bacterial, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, MESH: Diarrhea, MESH: Gene Expression Profiling, MESH: Spores, Bacterial, MESH: Germ-Free Life, MESH: Up-Regulation, MESH: Animals, MESH: Gastrointestinal Tract, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], MESH: Mice, Inbred C3H, MESH: Bacterial Proteins, MESH: Mice, MESH: Female, MESH: Clostridium difficile, MESH: Virulence Factors