المؤلفون: Jean-Yves Tinevez, Vanessa Ribes, Cécile St Cloment, Miguel Lopes, Philippe Daubas, Céline Bourcier de Carbon, Nathalie Duval, Benoît Robert

المساهمون: Génétique Moléculaire de la Morphogénèse, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Génétique Moléculaire du Développement, Imagerie Dynamique (Plate-Forme) (PFID), Institut Pasteur [Paris], Groupe Myologie, Institut de Myologie, Université Pierre et Marie Curie - Paris 6 (UPMC)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Association française contre les myopathies (AFM-Téléthon)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Association française contre les myopathies (AFM-Téléthon)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by the Institut Pasteur, the Centre National de la Recherche Scientifique and the Agence Nationale de la Recherche [Laboratoire d'Excellence Revive, Investissement d'Avenir, ANR-10-LABX-73]. M.L. was supported by grants from the Fundação para a Ciência e a Tecnologia (FCT) [SFRH/BD/36875/2007]., We are grateful to Dr A. Mansouri for the Pax7lacZ mouse strain, Prof. C. Petit and Dr L. Lepelletier for the Math1/mCherry mouse strain, Prof. J. Johnson for murine Atoh1 3′ enhancer plasmid, Prof. C. Birchmeier for anti-Olig3 antibody and Drs B. Durand and S. Rétaux for the Barhl2 and Lmx1a probes. We thank the Mouse Genetics Engineering Center (Institut Pasteur), J. F. Ouimette and C. Rougeulle for advice in setting up the ChIP experiments, C. Cimper and L. Papon for technical assistance, and I. Le Roux for critical reading of the manuscript., ANR-10-LABX-0073,REVIVE,Stem Cells in Regenerative Biology and Medicine(2010), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP), Tinevez, Jean-Yves, Laboratoires d'excellence - Stem Cells in Regenerative Biology and Medicine - - REVIVE2010 - ANR-10-LABX-0073 - LABX - VALID

المصدر: Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2014, 141 (8), pp.1726-1736. ⟨10.1242/dev.099002⟩
Development (Cambridge, England), 2014, 141 (8), pp.1726-1736. ⟨10.1242/dev.099002⟩

مصطلحات موضوعية: [SDV]Life Sciences [q-bio], MESH: Embryo, Mammalian / metabolism, MESH: Interneurons / cytology, MESH: Enhancer Elements, Genetic / genetics, MESH: Base Sequence, Mice, 0302 clinical medicine, MESH: Spinal Cord / embryology, Transcriptional regulation, Basic Helix-Loop-Helix Transcription Factors, MESH: Animals, MESH: Stem Cells / metabolism, 0303 health sciences, Stem Cells, MESH: Basic Helix-Loop-Helix Transcription Factors / genetics, MESH: Spinal Cord / metabolism, Neurogenesis, Gene Expression Regulation, Developmental, Cell Differentiation, MESH: Cell Differentiation / genetics, [SDV] Life Sciences [q-bio], ASCL1, Enhancer Elements, Genetic, MESH: Interneurons / metabolism, Spinal Cord, Developing spinal cord, Bone Morphogenetic Proteins, Spinal cord patterning, MESH: Signal Transduction / genetics, Protein Binding, Signal Transduction, Molecular Sequence Data, MESH: Basic Helix-Loop-Helix Transcription Factors / metabolism, MESH: Bone Morphogenetic Proteins / metabolism, Cell fate determination, Biology, Homeodomain transcription factor, 03 medical and health sciences, Interneurons, MESH: Protein Binding / genetics, Animals, MESH: Gene Expression Regulation, Developmental, Enhancer, Molecular Biology, Transcription factor, MESH: Mice, 030304 developmental biology, Homeodomain Proteins, MSX1 Transcription Factor, Binding Sites, MESH: Molecular Sequence Data, Base Sequence, MESH: Mutation / genetics, Embryo, Mammalian, Molecular biology, stomatognathic diseases, MESH: Binding Sites, MESH: Homeodomain Proteins / metabolism, Mutation, Homeobox, MESH: MSX1 Transcription Factor / metabolism, 030217 neurology & neurosurgery, Developmental Biology

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https://hal-pasteur.archives-ouvertes.fr/pasteur-02616459