المؤلفون: Julia Hoeng, David Bovard, Karsta Luettich, Albert Giralt, Stefan Frentzel, Athanasios Kondylis, Keyur Trivedi, Anita Iskandar, Laurent Neau, Petros Kanellos, Manuel C. Peitsch

المصدر: Current Research in Toxicology, Vol 1, Iss, Pp 56-69 (2020)
Current Research in Toxicology

مصطلحات موضوعية: Health, Toxicology and Mutagenesis, TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin, Stimulation, Toxicology, Applied Microbiology and Biotechnology, Article, BTUB4, β-tubulin 4, ALI, air–liquid interface, TEER, transepithelial electrical resistance, Basal (phylogenetics), PBS, phosphate buffered saline, Donor variability, lcsh:RA1190-1270, Organotypic, medicine, Lung toxicology, lcsh:Toxicology. Poisons, Lung, biology, Cytochrome P450, CBF, cilia beating frequency, respiratory system, In vitro, Epithelium, Cell biology, medicine.anatomical_structure, MUC5AC, mucin 5AC, Bronchial culture, Small airway culture, Toxicity, biology.protein, CYP, cytochrome P450, Drug metabolism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209f9d4739d978406cce3bbc04e2d3fb
https://doi.org/10.1016/j.crtox.2020.08.002

المؤلفون: Jessica Budde, Oleg Brinster, Fan Yu, Lukasz Czekala, Roman Wieczorek, Matthew Stevenson, Kathryn Rudd, Thomas Verron, Tanvir Walele, Edgar Trelles Sticken, Liam Simms

المصدر: Current Research in Toxicology
Current Research in Toxicology, Vol 2, Iss, Pp 99-115 (2021)

مصطلحات موضوعية: THR, Tobacco Harm Reduction, MIE, Molecular Initiating Event, Health, Toxicology and Mutagenesis, DPBS, Dulbecco's phosphate-buffered saline containing Ca2+ and Mg2+, EVP, Electronic Vapor Product, AOP, Adverse Outcome Pathway, Pharmacology, Toxicology, Applied Microbiology and Biotechnology, MWP, Multi-Well Plate, TNF-α, Tumor Necrosis Factor Alpha, RA1190-1270, Cigarette smoke, 3D, Three Dimensional, Respiratory system, Cigarette, Tobacco harm reduction, ANOVA, Analysis of Variance, FOX-J1, Forkhead Box J1 protein, H&E, Hematoxylin and Eosin, Immunohistochemistry, NKT, Natural Killer T Cells, medicine.anatomical_structure, CAA, Cilia Active Area, IIVS, Institute for In Vitro Sciences, TEER, Transepithelial Electrical Resistance, IL-8, Interleukin-8, PBS, Phosphate Buffered Saline, Organotypic tissue model, CBF, Cilia Beat Frequency, ALI, Air-Liquid Interface, PMN, polymorphonuclear, KERs, Key Event Relationships, Article, MMP-1, Matrix Metalloproteinase-1, MMP-3, Matrix Metalloproteinase-3, medicine, IL-13, Interleukin 13, Cilia, IL-6, Interleukin-6, MUC5AC, Mucin 5AC Protein, ComputingMethodologies_COMPUTERGRAPHICS, Smoke, Lung, LDH, Lactate Dehydrogenase, business.industry, COPD, Chronic Obstructive Pulmonary Disease, CYP450, Cytochrome P450, TPM, Total Particulate Matter, Human airway, 3R4F, Scientific Reference Tobacco Cigarette (University of Kentucky), Aerosol, SAEIVS, Smoke Aerosol Exposure In Vitro System, Pro-inflammatory markers, Electronic vapor product, Toxicology. Poisons, Respiratory epithelium, ISO, International Organization for Standardization, EGFR, Epidermal Growth Factor Receptor, business, 2D, Two Dimensional, KEs, Key Events, MMP-9, Matrix Metalloproteinase-9, IL-1β, Interleukin 1 Beta

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba67fdc3a02685b761410ce5bf3b080
https://pubmed.ncbi.nlm.nih.gov/34345855

المؤلفون: Eduard F. Stange

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 1, Pp 352-353 (2021)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: GFHP, glucose-free high-protein, SDS, sodium dodecyl sulfate, OXPHOS, oxidative phosphorylation, SPDEF, SAM pointed domain-containing Ets transcription factor, RC799-869, Mitochondrion, KLF4, Kruppel-like factor 4, Bioinformatics, IgA, immunoglobulin A, Text mining, CD, Crohn’s disease, Medicine, Humans, OCR, oxygen consumption rate, C1QBP, Mucus Barrier, Original Research, ATOH1, atonal basic helix-loop-helix transcription factor 1, ECAR, extracellular acidification rate, Hepatology, IBD, inflammatory bowel disease, business.industry, Inflammatory Bowel Disease, Gastroenterology, siRNA, silencing RNA, HRP, horseradish peroxidase, ELISA, enzyme-linked immunosorbent assay, respiratory system, Diseases of the digestive system. Gastroenterology, medicine.disease, Ulcerative colitis, WT, wild-type, mRNA, messenger RNA, Mitochondria, MUC2, mucin 2, UC, ulcerative colitis, MUC5AC, mucin 5AC, Colitis, Ulcerative, DMEM, Dulbecco’s modified Eagle medium, business, Mitochondrial Function

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33a6365d030a91b98e53ff324d45a2e
http://www.sciencedirect.com/science/article/pii/S2352345X21000394

المؤلفون: Guo Ping Shi, Cong Lin Liu

المصدر: World Allergy Organization Journal, Vol 12, Iss 11, Pp-(2019)
The World Allergy Organization Journal

مصطلحات موضوعية: Respiratory diseases, KCNMB1, potassium calcium-activated channel subfamily M regulatory beta subunit 1, TNF-α, tumor necrosis factor-α, Cystic fibrosis, AMCase, acidic mammalian chitinase, Bpifa1, bactericidal/permeability-increasing protein (BPI) fold-containing family A member 1, CeO2NPs, cerium dioxide nanoparticles, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, CLCA1, calcium-activated chloride channel regulator 1, BALF, bronchoalveolar lavage fluid, Immunology and Allergy, Medicine, β4BMs, β4-binding motifs, DSS, dextran sodium sulfate, 030223 otorhinolaryngology, Cancer, Innate immunity, biology, NFA, niflumic acid, Gastrointestinal disease, STAT6, signal transducer and activator of transcription 6, Cystic fibrosis transmembrane conductance regulator, cAMP, cyclic adenosine monophosphate, Lymphatic Endothelium, Lymphatic system, medicine.anatomical_structure, MUC5AC, mucin 5AC, FAK, focal adhesion kinase, SPDEF, sterile alpha motif [SAM] domain-containing prostate-derived Ets transcription factor, EMT, epithelial-mesenchymal transition, Gob-5, goblet cell protein-5, lcsh:Immunologic diseases. Allergy, Pulmonary and Respiratory Medicine, IAD, inflammatory airway diseases, CXCL-1, C-X-C motif chemokine ligand 1, LFC, log2 fold change, government.form_of_government, Immunology, CaCCs, calcium-activated chloride channels, Article, OVA, ovalbumin, 03 medical and health sciences, CFTR, cystic fibrosis transmembrane conductance regulator, TMEM16A, transmembrane protein 16A, CLCA1, CF, cystic fibrosis, Goblet cell, Innate immune system, VWA, von Willebrand factor type A, business.industry, Mucin, HDMA, house dust mite allergen, medicine.disease, WT, wild-type, LFA-1, lymphocyte function-associated antigen 1, Mucus, EGFR, epidermal growth factor receptor, EpOCs, epithelial organoid cultures, COPD, chronic obstructive pulmonary disease, 030228 respiratory system, DOG1, discovered on gastrointestinal stromal tumours-1, Cancer research, government, biology.protein, rIFABP, rat intestinal fatty acid binding protein promoter, lcsh:RC581-607, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1085881760dd3b6693c8aa6edbb2de
https://doi.org/10.1016/j.waojou.2019.100077

المؤلفون: Richard Leigh, David Proud

المصدر: Pharmacology & Therapeutics

مصطلحات موضوعية: Rhinovirus, Syk, spleen tyrosine kinase, Respiratory Tract Diseases, RIP-1, receptor interacting protein-1, Epithelial cells, ICAM-1, intercellular adhesion molecule-1, Cystic fibrosis, Human rhinovirus, OAS, 2′5′-oligoadenylate synthetase, TRAF-3, TNF receptor-associated factor-3, Pathogenesis, CCL, chemokine (C-C motif) ligand, Pharmacology (medical), Respiratory system, mda-5, melanoma differentiation-associated gene-5, Innate immunity, COPD, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, Airway remodeling, CXCR, C-X-C chemokine receptor, VEGF, vascular endothelial growth factor, medicine.anatomical_structure, iNOS, inducible nitric oxide synthase, PAMP, pathogen-associated molecular pattern, TRIF, TIR-domain-containing adapter-inducing interferon-β, IPS-1, interferon-β promoter stimulating protein-1, COAST, Childhood Origins of Asthma, RT-PCR, reverse transcription-polymerase chain reaction, T helper 2, Th2, GM-CSF, granulocyte–macrophage colony-stimulating factor, HRV, human rhinovirus, ERK, extracellular-signal-regulated kinase, Antiviral Agents, Virus, Article, LABA, Long-acting β2-adrenergic agonist, medicine, Animals, Humans, ISG, interferon-stimulated gene, IFN, interferon, TLR, toll-like receptor, OCT, octamer transcription factor, Asthma, Respiratory Sounds, Pharmacology, CF, cystic fibrosis, CXCL, chemokine (C-X-C motif) ligand, FADD, fas-associated protein with death domain, MUC5AC, Mucin 5AC, NO, nitric oxide, Picornaviridae Infections, business.industry, MMP-9, matrix metalloproteinase-9, medicine.disease, G-CSF, granulocyte colony-stimulating factor, ICS, inhaled corticosteroids, Immunity, Innate, respiratory tract diseases, IL, interleukin, RIG-I, retinoic acid inducible gene-I, COPD, chronic obstructive pulmonary disease, PI-3 kinase, phosphatidylinositol-4,5-bisphosphate 3-kinase, PRR, pattern recognition receptors, Immunology, RNA, ribonucleic acid, dsRNA, double-stranded RNA, RSV, respiratory syncytial virus, business, Airway, Respiratory tract, IRF, interferon regulatory factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ceb543ec1943de9596fcd25ba010883
https://pubmed.ncbi.nlm.nih.gov/25550230

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المؤلفون: Czekala L; Imperial Brands PLC, 121 Winterstoke Road, Bristol BS3 2LL, United Kingdom., Wieczorek R; Reemtsma Cigarettenfabriken GmbH, An Imperial Brands PLC Company, Albert-EinsteinRing-7, D-22761 Hamburg, Germany., Simms L; Imperial Brands PLC, 121 Winterstoke Road, Bristol BS3 2LL, United Kingdom., Yu F; Imperial Brands PLC, 121 Winterstoke Road, Bristol BS3 2LL, United Kingdom., Budde J; Reemtsma Cigarettenfabriken GmbH, An Imperial Brands PLC Company, Albert-EinsteinRing-7, D-22761 Hamburg, Germany., Trelles Sticken E; Reemtsma Cigarettenfabriken GmbH, An Imperial Brands PLC Company, Albert-EinsteinRing-7, D-22761 Hamburg, Germany., Rudd K; Imperial Brands PLC, 121 Winterstoke Road, Bristol BS3 2LL, United Kingdom., Verron T; Imperial Brands PLC, 121 Winterstoke Road, Bristol BS3 2LL, United Kingdom., Brinster O; Reemtsma Cigarettenfabriken GmbH, An Imperial Brands PLC Company, Albert-EinsteinRing-7, D-22761 Hamburg, Germany., Stevenson M; Imperial Brands PLC, 121 Winterstoke Road, Bristol BS3 2LL, United Kingdom., Walele T; Imperial Brands PLC, 121 Winterstoke Road, Bristol BS3 2LL, United Kingdom.

المصدر: Current research in toxicology [Curr Res Toxicol] 2021 Feb 20; Vol. 2, pp. 99-115. Date of Electronic Publication: 2021 Feb 20 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101771915 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-027X (Electronic) Linking ISSN: 2666027X NLM ISO Abbreviation: Curr Res Toxicol Subsets: PubMed not MEDLINE

المؤلفون: Bovard D; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland., Giralt A; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland., Trivedi K; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland., Neau L; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland., Kanellos P; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland., Iskandar A; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland., Kondylis A; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland., Luettich K; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland., Frentzel S; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland., Hoeng J; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland., Peitsch MC; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland.

المصدر: Current research in toxicology [Curr Res Toxicol] 2020 Sep 04; Vol. 1, pp. 56-69. Date of Electronic Publication: 2020 Sep 04 (Print Publication: 2020).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101771915 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-027X (Electronic) Linking ISSN: 2666027X NLM ISO Abbreviation: Curr Res Toxicol Subsets: PubMed not MEDLINE

المؤلفون: Liu CL; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China.; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA., Shi GP; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China.; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.

المصدر: The World Allergy Organization journal [World Allergy Organ J] 2019 Nov 29; Vol. 12 (11), pp. 100077. Date of Electronic Publication: 2019 Nov 29 (Print Publication: 2019).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101481283 Publication Model: eCollection Cited Medium: Print ISSN: 1939-4551 (Print) Linking ISSN: 19394551 NLM ISO Abbreviation: World Allergy Organ J Subsets: PubMed not MEDLINE