المؤلفون: Schnitzler, Gavin R.^{Aff1, Aff2, Aff3}, Kang, Helen^{Aff4, Aff5}, Fang, Shi^{Aff1, Aff3}, Angom, Ramcharan S., Lee-Kim, Vivian S.^{Aff1, Aff3}, Ma, X. Rosa^{Aff4, Aff5}, Zhou, Ronghao^{Aff4, Aff5}, Zeng, Tony^{Aff4, Aff5}, Guo, Katherine^{Aff4, Aff5}, Taylor, Martin S., Vellarikkal, Shamsudheen K.^{Aff1, Aff3}, Barry, Aurelie E.^{Aff1, Aff3}, Sias-Garcia, Oscar^{Aff1, Aff3}, Bloemendal, Alex^{Aff1, Aff2}, Munson, Glen, Guckelberger, Philine, Nguyen, Tung H., Bergman, Drew T.^{Aff1, Aff8}, Hinshaw, Stephen, Cheng, Nathan, Cleary, Brian^{Aff1, Aff10}, Aragam, Krishna^{Aff1, Aff11}, Lander, Eric S.^{Aff1, Aff12, Aff13}, Finucane, Hilary K.^{Aff1, Aff14, Aff15, Aff16}, Mukhopadhyay, Debabrata, Gupta, Rajat M.^{Aff1, Aff2, Aff3, IDs4158602407022x_cor26}, Engreitz, Jesse M.^{Aff1, Aff2, Aff4, Aff5, Aff17, IDs4158602407022x_cor27}

المصدر: Nature: International weekly journal of science. 626(8000):799-807

المؤلفون: Ma, X Rosa, Prudencio, Mercedes, Koike, Yuka, Vatsavayai, Sarat C, Kim, Garam, Harbinski, Fred, Briner, Adam, Rodriguez, Caitlin M, Guo, Caiwei, Akiyama, Tetsuya, Schmidt, H Broder, Cummings, Beryl B, Wyatt, David W, Kurylo, Katherine, Miller, Georgiana, Mekhoubad, Shila, Sallee, Nathan, Mekonnen, Gemechu, Ganser, Laura, Rubien, Jack D, Jansen-West, Karen, Cook, Casey N, Pickles, Sarah, Oskarsson, Björn, Graff-Radford, Neill R, Boeve, Bradley F, Knopman, David S, Petersen, Ronald C, Dickson, Dennis W, Shorter, James, Myong, Sua, Green, Eric M, Seeley, William W, Petrucelli, Leonard, Gitler, Aaron D

المصدر: Nature. 603(7899)

مصطلحات موضوعية: Biological Sciences, Biomedical and Clinical Sciences, Genetics, Rare Diseases, Stem Cell Research - Nonembryonic - Human, Dementia, Neurosciences, Brain Disorders, Acquired Cognitive Impairment, Human Genome, Stem Cell Research, Neurodegenerative, ALS, 2.1 Biological and endogenous factors, Aetiology, Neurological, Amyotrophic Lateral Sclerosis, DNA-Binding Proteins, Exons, Frontotemporal Dementia, Genome-Wide Association Study, Humans, Motor Neurons, Nerve Tissue Proteins, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1062r1nd

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المؤلفون: Gschwind AR; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Basic Sciences and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford, CA, USA., Mualim KS; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Plant Biology, Carnegie Institute of Science, Stanford, CA, USA., Karbalayghareh A; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Sheth MU; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Basic Sciences and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford, CA, USA.; Department of Bioengineering, Stanford University, Stanford, CA, USA., Dey KK; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA., Jagoda E; The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Nurtdinov RN; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Catalonia, Spain., Xi W; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Tan AS; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Basic Sciences and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford, CA, USA., Jones H; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Basic Sciences and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford, CA, USA., Ma XR; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Basic Sciences and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford, CA, USA., Yao D; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Nasser J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Present Address: Department of Systems Biology, Harvard Medical School, Boston, MA, USA., Avsec Ž; Google DeepMind, London, UK., James BT; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA., Shamim MS; The Center for Genome Architecture, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.; Center for Theoretical Biological Physics, Rice University, Houston, TX, USA.; Department of Bioengineering, Rice University, Houston, TX, USA.; Medical Scientist Training Program, Baylor College of Medicine, Houston, Texas, USA., Durand NC; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; The Center for Genome Architecture, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.; Center for Theoretical Biological Physics, Rice University, Houston, TX, USA.; Department of Computer Science, Rice University, Houston, TX, USA., Rao SSP; The Center for Genome Architecture, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.; Department of Structural Biology, Stanford University, Stanford, CA, USA., Mahajan R; The Center for Genome Architecture, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.; Center for Theoretical Biological Physics, Rice University, Houston, TX, USA.; Department of Biosciences, Rice University, Houston, TX, USA., Doughty BR; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Andreeva K; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Ulirsch JC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Present Address: Artificial Intelligence Laboratory, Illumina, Inc., San Diego, CA, USA., Fan K; Program in Bioinformatics and Integrative Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.; Present Address: Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Perez EM; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Nguyen TC; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Basic Sciences and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford, CA, USA., Kelley DR; Calico Life Sciences, South San Francisco, CA, USA., Finucane HK; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Moore JE; Program in Bioinformatics and Integrative Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Weng Z; Program in Bioinformatics and Integrative Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Kellis M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA., Bassik MC; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Price AL; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA., Beer MA; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Guigó R; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Catalonia, Spain., Stamatoyannopoulos JA; Altius Institute for Biomedical Sciences, Seattle, WA, USA.; Clinical Research Division, Fred Hutch Cancer Center, Seattle, WA, USA., Lieberman Aiden E; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; The Center for Genome Architecture, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.; Center for Theoretical Biological Physics, Rice University, Houston, TX, USA.; Department of Computer Science, Rice University, Houston, TX, USA., Greenleaf WJ; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Applied Physics, Stanford University, Stanford, CA, USA., Leslie CS; Memorial Sloan Kettering Cancer Center, New York, NY, USA., Steinmetz LM; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Genome Technology Center, Palo Alto, CA, USA.; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany., Kundaje A; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Computer Science, Stanford University, Stanford, CA, USA., Engreitz JM; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Basic Sciences and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford, CA, USA.; The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Nov 13. Date of Electronic Publication: 2023 Nov 13.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Boeynaems S; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.; Therapeutic Innovation Center (THINC), Baylor College of Medicine, Houston, TX 77030, USA.; Center for Alzheimer's and Neurodegenerative Diseases (CAND), Texas Children's Hospital, Houston, TX 77030, USA.; Dan L Duncan Comprehensive Cancer Center (DLDCCC), Baylor College of Medicine, Houston, TX 77030, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA., Ma XR; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA., Yeong V; Department of Chemical Engineering, Columbia University, New York, NY, 10027, USA., Ginell GM; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110, USA.; Center for Biomolecular Condensates, Washington University in St Louis, St. Louis, MO 63130, USA., Chen JH; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.; Department of Anatomy, University of California, San Francisco, CA 94143, USA., Blum JA; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA., Nakayama L; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA., Sanyal A; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA., Briner A; Clem Jones Centre for Ageing Dementia Research (CJCADR), Queensland Brain Institute (QBI), The University of Queensland, Brisbane, QLD 4072, Australia., Haver DV; VIB-UGent Center for Medical Biotechnology, 9000 Gent, Belgium.; VIB Proteomics Core, 9000 Gent, Belgium.; Department of Biochemistry, Ghent University, 9000 Gent, Belgium., Pauwels J; VIB-UGent Center for Medical Biotechnology, 9000 Gent, Belgium.; VIB Proteomics Core, 9000 Gent, Belgium.; Department of Biochemistry, Ghent University, 9000 Gent, Belgium., Ekman A; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.; Department of Anatomy, University of California, San Francisco, CA 94143, USA., Schmidt HB; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA., Sundararajan K; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA., Porta L; Department of Pharmacology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), Sao Paulo, Brazil., Lasker K; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Larabell C; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.; Department of Anatomy, University of California, San Francisco, CA 94143, USA., Hayashi MAF; Department of Pharmacology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), Sao Paulo, Brazil., Kundaje A; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Computer Science, Stanford University, Stanford, CA 94305, USA., Impens F; VIB-UGent Center for Medical Biotechnology, 9000 Gent, Belgium.; VIB Proteomics Core, 9000 Gent, Belgium.; Department of Biochemistry, Ghent University, 9000 Gent, Belgium., Obermeyer A; Department of Chemical Engineering, Columbia University, New York, NY, 10027, USA., Holehouse AS; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110, USA.; Center for Biomolecular Condensates, Washington University in St Louis, St. Louis, MO 63130, USA., Gitler AD; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Mar 09. Date of Electronic Publication: 2023 Mar 09.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE