المؤلفون: Malone CF; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA., Mabe NW; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA., Forman AB; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Alexe G; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA., Engel KL; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Chen YC; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; The Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Soeung M; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA., Salhotra S; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Basanthakumar A; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Liu B; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; The Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Dent SYR; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; The Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Stegmaier K; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.

المصدر: Science advances [Sci Adv] 2024 May 31; Vol. 10 (22), pp. eadm9449. Date of Electronic Publication: 2024 May 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: Neuroblastoma*/genetics , Neuroblastoma*/metabolism , Neuroblastoma*/pathology , N-Myc Proto-Oncogene Protein*/genetics , N-Myc Proto-Oncogene Protein*/metabolism , Gene Expression Regulation, Neoplastic*, Humans ; Cell Line, Tumor ; Histone Acetyltransferases/metabolism ; Histone Acetyltransferases/genetics ; Acetylation ; Histones/metabolism ; Animals ; Gene Amplification ; Chromatin/metabolism ; Chromatin/genetics ; Mice

المؤلفون: Lu DY; Harvard/MIT MD-PhD Program, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ellegast JM; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ross KN; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Malone CF; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lin S; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Mabe NW; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Dharia NV; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Meyer A; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Conway A; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Su AH; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Selich-Anderson J; Center for Childhood Cancer and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA., Taslim C; Center for Childhood Cancer and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA., Byrum AK; Center for Childhood Cancer and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA., Seong BKA; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Adane B; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Gray NS; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Rivera MN; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA., Lessnick SL; Center for Childhood Cancer and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.; Division of Pediatric Hematology, Oncology and BMT, The Ohio State University College of Medicine, Columbus, OH, USA., Stegmaier K; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA. Kimberly_Stegmaier@dfci.harvard.edu.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA. Kimberly_Stegmaier@dfci.harvard.edu.

المصدر: Nature cell biology [Nat Cell Biol] 2023 Feb; Vol. 25 (2), pp. 285-297. Date of Electronic Publication: 2023 Jan 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: Sarcoma, Ewing*/genetics, Child ; Humans ; Cell Line, Tumor ; Cell Transformation, Neoplastic/genetics ; Gene Expression Regulation, Neoplastic ; Oncogene Proteins, Fusion/genetics ; Oncogene Proteins, Fusion/metabolism ; Proto-Oncogene Protein c-fli-1/genetics ; Proto-Oncogene Protein c-fli-1/metabolism ; Proto-Oncogene Proteins c-ets/genetics ; RNA-Binding Protein EWS/genetics ; RNA-Binding Protein EWS/metabolism

المؤلفون: So J; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Mabe NW; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorder Center and Harvard Medical School, Boston, Massachusetts, USA., Englinger B; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorder Center and Harvard Medical School, Boston, Massachusetts, USA.; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria., Chow KH; Department of Oncologic Pathology and.; Center for Patient Derived Models, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA., Moyer SM; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Yerrum S; Department of Oncologic Pathology and.; Center for Patient Derived Models, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA., Trissal MC; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorder Center and Harvard Medical School, Boston, Massachusetts, USA., Marques JG; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorder Center and Harvard Medical School, Boston, Massachusetts, USA., Kwon JJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Shim B; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Pal S; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Panditharatna E; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorder Center and Harvard Medical School, Boston, Massachusetts, USA., Quinn T; Department of Oncologic Pathology and.; Center for Patient Derived Models, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA., Schaefer DA; Department of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorder Center and Harvard Medical School, Boston, Massachusetts, USA., Jeong D; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorder Center and Harvard Medical School, Boston, Massachusetts, USA., Mayhew DL; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Radiation Oncology, Tufts Medical Center, Boston, Massachusetts, USA., Hwang J; Department of Medicine and.; Masonic Cancer Center, University of Minnesota-Twin Cities, Minneapolis, Minnesota, USA., Beroukhim R; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Ligon KL; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.; Department of Oncologic Pathology and., Stegmaier K; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorder Center and Harvard Medical School, Boston, Massachusetts, USA., Filbin MG; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorder Center and Harvard Medical School, Boston, Massachusetts, USA., Hahn WC; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

المصدر: JCI insight [JCI Insight] 2022 Oct 10; Vol. 7 (19). Date of Electronic Publication: 2022 Oct 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Glioma*/genetics , Neuroblastoma*/genetics , Vaccinia*, Child ; Humans ; Intracellular Signaling Peptides and Proteins ; Nervous System ; Protein Serine-Threonine Kinases/genetics ; Vaccinia virus

المؤلفون: Mabe NW; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Huang M; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA., Dalton GN; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA., Alexe G; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Schaefer DA; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA, USA., Geraghty AC; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Robichaud AL; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA, USA., Conway AS; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA, USA., Khalid D; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA, USA., Mader MM; Institute for Stem Cell Biology and Regenerative Medicine, Stanford, CA, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Belk JA; Department of Computer Science, Stanford University School of Medicine, Stanford, CA, USA., Ross KN; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sheffer M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Linde MH; Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, CA, USA.; Immunology Graduate Program, Stanford University School of Medicine, Stanford, CA, USA., Ly N; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Yao W; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Rotiroti MC; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA., Smith BAH; Department of Chemical & Systems Biology, Stanford University School of Medicine, Stanford, CA, USA., Wernig M; Institute for Stem Cell Biology and Regenerative Medicine, Stanford, CA, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Bertozzi CR; Department of Chemistry, Stanford University School of Medicine, Stanford, CA, USA.; Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA., Monje M; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.; Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA., Mitsiades CS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Majeti R; Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, CA, USA., Satpathy AT; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA., Stegmaier K; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA, USA. Kimberly_stegmaier@dfci.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Kimberly_stegmaier@dfci.harvard.edu., Majzner RG; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA. rmajzner@stanford.edu.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA. rmajzner@stanford.edu.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA. rmajzner@stanford.edu.

المصدر: Nature cancer [Nat Cancer] 2022 Aug; Vol. 3 (8), pp. 976-993. Date of Electronic Publication: 2022 Jul 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Gangliosides* , Neuroblastoma*/drug therapy, Antibodies, Monoclonal ; Child ; Humans ; Immunotherapy ; Neoplasm Recurrence, Local/chemically induced

المؤلفون: Mabe NW; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA., Garcia NMG; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA., Wolery SE; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA., Newcomb R; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA., Meingasner RC; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA., Vilona BA; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA., Lupo R; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA., Lin CC; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA; Center for Genomic and Computational Biology, Duke University, Durham, NC 27710, USA., Chi JT; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA; Center for Genomic and Computational Biology, Duke University, Durham, NC 27710, USA., Alvarez JV; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA. Electronic address: james.alvarez@duke.edu.

المصدر: Cell reports [Cell Rep] 2020 Nov 03; Vol. 33 (5), pp. 108341.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Histone-Lysine N-Methyltransferase/*metabolism , Inflammation/*pathology , Mammary Neoplasms, Animal/*enzymology , Mammary Neoplasms, Animal/*pathology , Neoplasm Recurrence, Local/*pathology, Animals ; Cell Death ; Cell Survival ; Epigenesis, Genetic ; Female ; Gene Expression Regulation, Neoplastic ; Gene Silencing ; Histone-Lysine N-Methyltransferase/antagonists & inhibitors ; Mammary Neoplasms, Animal/genetics ; Mice, Nude ; Necroptosis ; Receptor-Interacting Protein Serine-Threonine Kinases/metabolism ; Risk Factors ; Transcription, Genetic ; Tumor Necrosis Factor-alpha/metabolism ; Tumor Suppressor Protein p53/metabolism

المؤلفون: Walens A; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA., Lin J; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, 27710, USA., Damrauer JS; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA., McKinney B; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA., Lupo R; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA., Newcomb R; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA., Fox DB; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA., Mabe NW; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA., Gresham J; Duke Cancer Institute, Duke University, Durham, NC, 27710, USA., Sheng Z; Duke Cancer Institute, Duke University, Durham, NC, 27710, USA., Sibley AB; Duke Cancer Institute, Duke University, Durham, NC, 27710, USA., De Buysscher T; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, 27599, USA.; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA., Kelkar H; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA., Mieczkowski PA; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, 27599, USA.; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA., Owzar K; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, 27710, USA.; Duke Cancer Institute, Duke University, Durham, NC, 27710, USA., Alvarez JV; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA. james.alvarez@duke.edu.

المصدر: Nature communications [Nat Commun] 2020 Oct 06; Vol. 11 (1), pp. 5017. Date of Electronic Publication: 2020 Oct 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Neoplastic*, Breast Neoplasms/*pathology , Neoplasm Recurrence, Local/*genetics , Neoplasm Recurrence, Local/*pathology, Animals ; Cell Line, Tumor ; Crizotinib/pharmacology ; Doxycycline/pharmacology ; Epithelial-Mesenchymal Transition/genetics ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Lung Neoplasms/pathology ; Lung Neoplasms/secondary ; Mice, Nude ; Neoplasm Recurrence, Local/drug therapy ; Proto-Oncogene Proteins c-met/antagonists & inhibitors ; Proto-Oncogene Proteins c-met/genetics ; Receptor, ErbB-2/genetics ; Single-Cell Analysis ; Xenograft Model Antitumor Assays

المؤلفون: Lin CC; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, 27710, USA.; Center for Genomic and Computational Biology, Duke University School of Medicine, Durham, NC, 27710, USA., Mabe NW; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, 27710, USA., Lin YT; Division Pediatric Hematology-Oncology, Duke University School of Medicine, Durham, NC, 27710, USA., Yang WH; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, 27710, USA.; Center for Genomic and Computational Biology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Biochemistry, Duke University School of Medicine, Durham, NC, 27710, USA., Tang X; Department of Biological Sciences, Michigan Technological University, Houghton, MI, 49931, USA., Hong L; Department of Chemistry and Biochemistry, University of Maryland, Baltimore County, Baltimore, MD, 21250, USA., Sun T; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, 27710, USA.; Center for Genomic and Computational Biology, Duke University School of Medicine, Durham, NC, 27710, USA., Force J; Duke Cancer Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Marks JR; Department of Surgery and Division of Surgical Sciences, Duke University School of Medicine, Durham, NC, 27710, USA., Yao TP; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, 27710, USA., Alvarez JV; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, 27710, USA., Chi JT; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, 27710, USA. jentsan.chi@duke.edu.; Center for Genomic and Computational Biology, Duke University School of Medicine, Durham, NC, 27710, USA. jentsan.chi@duke.edu.

المصدر: Cell death and differentiation [Cell Death Differ] 2020 Jul; Vol. 27 (7), pp. 2234-2247. Date of Electronic Publication: 2020 Jan 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5403 (Electronic) Linking ISSN: 13509047 NLM ISO Abbreviation: Cell Death Differ Subsets: MEDLINE

مواضيع طبية MeSH: Cystine/*metabolism , Mammary Neoplasms, Animal/*pathology , Neoplasm Recurrence, Local/*pathology , Receptor-Interacting Protein Serine-Threonine Kinases/*genetics , Up-Regulation/*genetics, Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Cell Proliferation/drug effects ; Epigenesis, Genetic/drug effects ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Mammary Neoplasms, Animal/genetics ; Mitosis/drug effects ; Neoplasm Recurrence, Local/genetics ; Piperazines/pharmacology ; Receptor-Interacting Protein Serine-Threonine Kinases/metabolism ; Signal Transduction/drug effects ; Transcriptome/genetics ; Tumor Stem Cell Assay ; Tumor Suppressor Protein p53/metabolism ; Up-Regulation/drug effects ; YAP-Signaling Proteins

المؤلفون: Rorabaugh BR; Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, Ohio Northern University, Ada, OH, USA., Mabe NW; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Seeley SL; Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, Ohio Northern University, Ada, OH, USA., Stoops TS; Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, Ohio Northern University, Ada, OH, USA., Mucher KE; Department of Psychology, Sociology, & Criminal Justice, Ohio Northern University, Ada, OH, USA., Ney CP; Department of Psychology, Sociology, & Criminal Justice, Ohio Northern University, Ada, OH, USA., Goodman CS; Department of Psychology, Sociology, & Criminal Justice, Ohio Northern University, Ada, OH, USA., Hertenstein BJ; Department of Psychology, Sociology, & Criminal Justice, Ohio Northern University, Ada, OH, USA., Rush AE; Department of Psychology, Sociology, & Criminal Justice, Ohio Northern University, Ada, OH, USA., Kasler CD; Department of Psychology, Sociology, & Criminal Justice, Ohio Northern University, Ada, OH, USA., Sargeant AM; Charles River Laboratories, Spencerville, OH, USA., Zoladz PR; Department of Psychology, Sociology, & Criminal Justice, Ohio Northern University, Ada, OH, USA.

المصدر: Stress (Amsterdam, Netherlands) [Stress] 2020 Mar; Vol. 23 (2), pp. 125-135. Date of Electronic Publication: 2019 Jul 26.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9617529 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1607-8888 (Electronic) Linking ISSN: 10253890 NLM ISO Abbreviation: Stress Subsets: MEDLINE

مواضيع طبية MeSH: Stress Disorders, Post-Traumatic*/genetics, Animals ; Cats ; Disease Models, Animal ; Endothelial Cells ; Fibrosis ; Inflammation/genetics ; Male ; Rats ; Stress, Psychological/genetics ; Transcriptome

المؤلفون: Mabe NW; Department of Pharmacology and Cancer Biology, and., Fox DB; Department of Pharmacology and Cancer Biology, and., Lupo R; Department of Pharmacology and Cancer Biology, and., Decker AE; Department of Pharmacology and Cancer Biology, and., Phelps SN; Department of Pharmacology and Cancer Biology, and., Thompson JW; Department of Pharmacology and Cancer Biology, and.; Center for Genomics and Computational Biology, Duke University, Durham, North Carolina, USA., Alvarez JV; Department of Pharmacology and Cancer Biology, and.

المصدر: The Journal of clinical investigation [J Clin Invest] 2018 Oct 01; Vol. 128 (10), pp. 4413-4428. Date of Electronic Publication: 2018 Aug 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: Drug Resistance, Neoplasm* , Epithelial-Mesenchymal Transition* , Gene Expression Regulation, Neoplastic* , Gene Silencing*, Apoptosis Regulatory Proteins/*biosynthesis , Breast Neoplasms/*metabolism , Neoplasm Recurrence, Local/*metabolism , Tumor Suppressor Proteins/*biosynthesis, Animals ; Antineoplastic Agents/pharmacology ; Apoptosis Regulatory Proteins/genetics ; Breast Neoplasms/drug therapy ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Enhancer of Zeste Homolog 2 Protein/genetics ; Enhancer of Zeste Homolog 2 Protein/metabolism ; Female ; Histone Deacetylase 1/genetics ; Histone Deacetylase 1/metabolism ; Histone Deacetylase 2/genetics ; Histone Deacetylase 2/metabolism ; Humans ; Mice ; Mice, Nude ; Neoplasm Recurrence, Local/drug therapy ; Neoplasm Recurrence, Local/genetics ; Neoplasm Recurrence, Local/pathology ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Tumor Suppressor Proteins/genetics ; Twist-Related Protein 1/genetics ; Twist-Related Protein 1/metabolism

المؤلفون: Damrauer JS; Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina., Phelps SN; Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina., Amuchastegui K; Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina., Lupo R; Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina., Mabe NW; Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina., Walens A; Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina., Kroger BR; Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina., Alvarez JV; Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina. james.alvarez@duke.edu.

المصدر: Molecular cancer research : MCR [Mol Cancer Res] 2018 Apr; Vol. 16 (4), pp. 599-609. Date of Electronic Publication: 2018 Jan 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101150042 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3125 (Electronic) Linking ISSN: 15417786 NLM ISO Abbreviation: Mol Cancer Res

مواضيع طبية MeSH: Up-Regulation*, Apoptosis Regulatory Proteins/*genetics , Breast Neoplasms/*metabolism , Forkhead Transcription Factors/*metabolism , Lapatinib/*pharmacology , Neoplasm Recurrence, Local/*metabolism, Apoptosis Regulatory Proteins/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; MCF-7 Cells ; Phosphatidylinositol 3-Kinases/metabolism ; Promoter Regions, Genetic ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction/drug effects