نتائج البحث - "Magalie Lalanne"

المساهمون: Biothérapies des maladies génétiques et cancers, Université Bordeaux Segalen - Bordeaux 2-Institut National de la Santé et de la Recherche Médicale (INSERM), Physiopathologie du cancer du foie

المصدر: Biochemical and Biophysical Research Communications
Biochemical and Biophysical Research Communications, Elsevier, 2019, 517, pp.677-683. ⟨10.1016/j.bbrc.2019.07.109⟩

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4fece8c35c965ad2109e31c1db5f84
https://doi.org/10.1016/j.bbrc.2019.07.109

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5

Iron chelation rescues hemolytic anemia and skin photosensitivity in congenital erythropoietic porphyria

المؤلفون: Jean-Marc Blouin, Raed Daher, Zoubida Karim, Cécile Ged, Aurélie Bedel, Fanny Morice-Picard, Laurent Gouya, Magalie Lalanne, Hervé Puy, François Moreau-Gaudry, Pierre Costet, Isabelle Lamrissi-Garcia, Emmanuel Richard

المساهمون: Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)

المصدر: Blood
Blood, American Society of Hematology, 2020, 136 (21), pp.2457-2468. ⟨10.1182/blood.2020006037⟩

مصطلحات موضوعية: Hemolytic anemia, Porphyria, Erythropoietic, Uroporphyrinogen III synthase, Congenital erythropoietic porphyria, Pharmacology, Biochemistry, Mice, chemistry.chemical_compound, 0302 clinical medicine, Deferiprone, Gene Knock-In Techniques, RNA, Small Interfering, Heme, ComputingMilieux_MISCELLANEOUS, 0303 health sciences, biology, Skin photosensitivity, Hematology, Hemolysis, 3. Good health, 030220 oncology & carcinogenesis, Female, RNA Interference, BLOOD Commentary, 5-Aminolevulinate Synthetase, Adult, Anemia, Hemolytic, Iron Overload, Porphyrins, Iron, Immunology, Iron Chelating Agents, Cell Line, 03 medical and health sciences, Erythroid Cells, Cell Line, Tumor, medicine, Animals, Humans, Photosensitivity Disorders, 030304 developmental biology, Cell Biology, medicine.disease, ALAS2, Disease Models, Animal, chemistry, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, Porphyria, Acute Intermittent, Peripheral Blood Stem Cells, biology.protein, Leukemia, Erythroblastic, Acute, CRISPR-Cas Systems

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b910936d3819515eac5c040e5dad1e9
https://hal.archives-ouvertes.fr/hal-03045807

6

Mutation-Specific Guide RNA for Compound Heterozygous Porphyria On-target Scarless Correction by CRISPR/Cas9 in Stem Cells

المؤلفون: Jérôme Toutain, Grégoire Cullot, Samuel Amintas, Emmanuel Richard, Isabelle Moranvillier, François Moreau-Gaudry, Florence Prat, Sandrine Dabernat, Aurélie Bedel, Magalie Lalanne, Isabelle Lamrissi-Garcia, Julian Boutin, Jean-Marc Blouin

المساهمون: Biothérapies des maladies génétiques et cancers, Université Bordeaux Segalen - Bordeaux 2-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Bordeaux [Bordeaux], Université de Bordeaux (UB), Laboratoire d'Excellence : Biogenèse et pathologies du globule rouge (Labex Gr-Ex), Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), CCSD, Accord Elsevier

المصدر: Stem Cell Reports
Stem Cell Reports, Elsevier, 2020, 15, pp.677-693. ⟨10.1016/j.stemcr.2020.07.015⟩

مصطلحات موضوعية: 0301 basic medicine, Heterozygote, precise genome editing, [SDV]Life Sciences [q-bio], Induced Pluripotent Stem Cells, Congenital erythropoietic porphyria, iPSCs, Biology, congenital erythropoietic porphyria, Compound heterozygosity, medicine.disease_cause, Biochemistry, Article, 03 medical and health sciences, Porphyrias, 0302 clinical medicine, CRISPR-Associated Protein 9, compound heterozygous recessive disease, Genetics, medicine, CRISPR, Humans, Guide RNA, Allele, Gene, CRISPR/Cas9, Alleles, Gene Editing, Mutation, Base Sequence, mutation specific, Cas9, Stem Cells, Cell Biology, Exons, Genetic Therapy, Uroporphyrinogen III Synthetase, gene therapy, 3. Good health, Clone Cells, [SDV] Life Sciences [q-bio], 030104 developmental biology, Karyotyping, CRISPR-Cas Systems, 030217 neurology & neurosurgery, Developmental Biology, RNA, Guide, Kinetoplastida

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51053ec3d97d81cab94b46e24416bec
https://hal.archives-ouvertes.fr/hal-03492339

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7

Genetic background influences hepcidin response to iron imbalance in a mouse model of hemolytic anemia (Congenital erythropoietic porphyria)

المؤلفون: Emmanuel Richard, Pierre Costet, Said Lyoumi, Cécile Ged, Thibaud Lefebvre, Magalie Lalanne, Hervé Puy, Zoubida Karim, Hubert de Verneuil, François Moreau-Gaudry, Isabelle Lamrissi-Garcia, Jean-Marc Blouin, Sarah Millot, Laurent Gouya

المساهمون: Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)

المصدر: Biochemical and Biophysical Research Communications
Biochemical and Biophysical Research Communications, Elsevier, 2019, 520 (2), pp.297-303. ⟨10.1016/j.bbrc.2019.09.141⟩

مصطلحات موضوعية: 0301 basic medicine, Hemolytic anemia, Male, medicine.medical_specialty, Iron Overload, Porphyrins, Anemia, Iron, Porphyria, Erythropoietic, Ferroportin, Biophysics, Congenic, Congenital erythropoietic porphyria, Mice, Inbred Strains, Biochemistry, Hemolysis, 03 medical and health sciences, 0302 clinical medicine, Hepcidins, Hepcidin, hemic and lymphatic diseases, Internal medicine, medicine, Animals, Molecular Biology, Cation Transport Proteins, ComputingMilieux_MISCELLANEOUS, Mice, Inbred BALB C, biology, business.industry, Cell Biology, medicine.disease, Uroporphyrinogen III Synthetase, 3. Good health, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Endocrinology, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, 030220 oncology & carcinogenesis, biology.protein, Erythropoiesis, Female, business