المؤلفون: de Cordova Kindermann S; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina-UNESC, Criciúma, Brazil., Caon G; Laboratório de Metabolismo e Endocrinologia Comparada, Departamento de Fisiologia, Universidade Federal do Rio Grande do Sul-UFRGS, Porto Alegre, Brazil., Boeck CR; Mestrado em Ciências da Saúde e da Vida, Programa de Pós-graduação em Nanociências, Universidade Franciscana, Santa Maria, Brazil., de Oliveira Bauer C; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina-UNESC, Criciúma, Brazil., Dos Santos da Silva N; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina-UNESC, Criciúma, Brazil., Possamai OL; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina-UNESC, Criciúma, Brazil., Longaretti LM; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina-UNESC, Criciúma, Brazil., Magenis ML; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina-UNESC, Criciúma, Brazil., Damiani AP; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina-UNESC, Criciúma, Brazil., de Oliveira Monteiro I; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina-UNESC, Criciúma, Brazil., de Andrade VM; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina-UNESC, Criciúma, Brazil.

المصدر: Journal of the science of food and agriculture [J Sci Food Agric] 2024 Jul 08. Date of Electronic Publication: 2024 Jul 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons Country of Publication: England NLM ID: 0376334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0010 (Electronic) Linking ISSN: 00225142 NLM ISO Abbreviation: J Sci Food Agric Subsets: MEDLINE

المؤلفون: Macan TP; Laboratory of Translational Biomedicine, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Criciúma, SC, Brazil; Environmental Health Department, Portuguese National Institute of Health Dr. Ricardo Jorge, Porto, Portugal., Magenis ML; Laboratory of Translational Biomedicine, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Criciúma, SC, Brazil., Damiani AP; Laboratory of Translational Biomedicine, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Criciúma, SC, Brazil., Monteiro IO; Laboratory of Translational Biomedicine, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Criciúma, SC, Brazil., Silveira GB; Laboratory of Experimental Physiopathology, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Criciúma, SC, Brazil., Zaccaron RP; Laboratory of Experimental Physiopathology, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Criciúma, SC, Brazil., Silveira PCL; Laboratory of Experimental Physiopathology, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Criciúma, SC, Brazil., Teixeira JPF; Environmental Health Department, Portuguese National Institute of Health Dr. Ricardo Jorge, Porto, Portugal., Gajski G; Mutagenesis Unit, Institute for Medical Research and Occupational Health, Zagreb, Croatia., Andrade VM; Laboratory of Translational Biomedicine, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Criciúma, SC, Brazil. Electronic address: vmoraesdeandrade@yahoo.com.br.

المصدر: Mutation research. Genetic toxicology and environmental mutagenesis [Mutat Res Genet Toxicol Environ Mutagen] 2024 Apr; Vol. 895, pp. 503739. Date of Electronic Publication: 2024 Feb 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101632149 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3592 (Electronic) Linking ISSN: 13835718 NLM ISO Abbreviation: Mutat Res Genet Toxicol Environ Mutagen Subsets: MEDLINE

مواضيع طبية MeSH: Bertholletia*/chemistry , Selenium*/pharmacology , Diabetes Mellitus, Type 2*/genetics, Humans ; Overweight ; Mouth Mucosa ; Lipids ; DNA Damage ; Genomic Instability

المؤلفون: Magenis ML; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina-UNESC, Criciúma, SC, Brazil., Damiani AP; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina-UNESC, Criciúma, SC, Brazil., Monteiro IO; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina-UNESC, Criciúma, SC, Brazil., Dagostin LS; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina-UNESC, Criciúma, SC, Brazil., Silva NDS; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina-UNESC, Criciúma, SC, Brazil., Scussel R; Laboratory of Experimental Pathophysiology, Graduate Program of Health Sciences, University of Southern Santa Catarina-UNESC, Criciúma, SC, Brazil., Nagashima S; Laboratory of Experimental Pathology, Pontifical Catholic University of Paraná-PUCPR, Paraná, SC, Brazil., Langie SAS; Department of Pharmacology & Toxicology, School for Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, The Netherlands., Pinho RA; Laboratory of Biochemistry Exercise Health, Pontifical Catholic University of Paraná-PUCPR, Paraná, SC, Brazil., de Andrade VM; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina-UNESC, Criciúma, SC, Brazil.

المصدر: Mutagenesis [Mutagenesis] 2024 Mar 12; Vol. 39 (2), pp. 119-140.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 8707812 Publication Model: Print Cited Medium: Internet ISSN: 1464-3804 (Electronic) Linking ISSN: 02678357 NLM ISO Abbreviation: Mutagenesis Subsets: MEDLINE

مواضيع طبية MeSH: Fructose*/adverse effects , Prenatal Exposure Delayed Effects*/metabolism, Pregnancy ; Mice ; Male ; Female ; Animals ; Humans ; Obesity ; Body Weight ; Adiposity ; Lactation

المؤلفون: Cavalheiro EKFF; Laboratory of Neurobiology of Inflammatory and Metabolic Processes, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Tubarão, Santa Catarina, Brazil., da Silva LE; Laboratory of Neurobiology of Inflammatory and Metabolic Processes, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Tubarão, Santa Catarina, Brazil., Oliveira MP; Laboratory of Neurobiology of Inflammatory and Metabolic Processes, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Tubarão, Santa Catarina, Brazil., Silva MG; Laboratory of Behavioral Neuroscience, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Tubarão, Santa Catarina, Brazil., Damiani AP; Laboratório de Biologia Celular e Molecular, Universidade do Extremo Sul Catarinense, UNESC, Avenida Universitária, 1105, Criciúma, Santa Catarina, Brazil., Ribeiro CB; Laboratório de Biologia Celular e Molecular, Universidade do Extremo Sul Catarinense, UNESC, Avenida Universitária, 1105, Criciúma, Santa Catarina, Brazil., Magenis ML; Laboratório de Biologia Celular e Molecular, Universidade do Extremo Sul Catarinense, UNESC, Avenida Universitária, 1105, Criciúma, Santa Catarina, Brazil., Cucker L; Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, University of Southern Santa Catarina, Criciúma, Santa Catarina, Brazil., Michels M; Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, University of Southern Santa Catarina, Criciúma, Santa Catarina, Brazil., Joaquim L; Laboratory of Neurobiology of Inflammatory and Metabolic Processes, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Tubarão, Santa Catarina, Brazil., Machado RS; Laboratory of Neurobiology of Inflammatory and Metabolic Processes, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Tubarão, Santa Catarina, Brazil., Vilela TC; Laboratory of Neurobiology of Inflammatory and Metabolic Processes, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Tubarão, Santa Catarina, Brazil., Bitencourt RM; Laboratory of Behavioral Neuroscience, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Tubarão, Santa Catarina, Brazil., Andrade VM; Laboratório de Biologia Celular e Molecular, Universidade do Extremo Sul Catarinense, UNESC, Avenida Universitária, 1105, Criciúma, Santa Catarina, Brazil., Dal-Pizzol F; Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, University of Southern Santa Catarina, Criciúma, Santa Catarina, Brazil., Petronilho F; Laboratory of Neurobiology of Inflammatory and Metabolic Processes, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Tubarão, Santa Catarina, Brazil., Tuon T; Laboratory of Neurobiology of Inflammatory and Metabolic Processes, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Tubarão, Santa Catarina, Brazil., Rezin GT; Laboratory of Neurobiology of Inflammatory and Metabolic Processes, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Tubarão, Santa Catarina, Brazil. Electronic address: gitezza@hotmail.com.

المصدر: Behavioural brain research [Behav Brain Res] 2022 Sep 26; Vol. 434, pp. 114019. Date of Electronic Publication: 2022 Jul 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8004872 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7549 (Electronic) Linking ISSN: 01664328 NLM ISO Abbreviation: Behav Brain Res Subsets: MEDLINE

مواضيع طبية MeSH: Parkinson Disease*, Animals ; Disease Models, Animal ; Inflammation ; Obesity ; Oxidative Stress ; Reserpine

المؤلفون: Magenis ML; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Damiani AP; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Franca IB; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., de Marcos PS; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Effting PS; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Muller AP; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., de Bem Silveira G; Laboratory of Experimental Pathophysiology, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Borges Correa MEA; Laboratory of Experimental Pathophysiology, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Medeiros EB; Laboratory of Experimental Neurology, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Silveira PCL; Laboratory of Experimental Pathophysiology, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Budni J; Laboratory of Experimental Neurology, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Boeck CR; Graduate Program in Nanosciences, Franciscan University Center - UNIFRA, Santa Maria, RS, Brazil., de Andrade VM; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil. Electronic address: vmoraesdeandrade@yahoo.com.br.

المصدر: Reproductive toxicology (Elmsford, N.Y.) [Reprod Toxicol] 2022 Sep; Vol. 112, pp. 119-135. Date of Electronic Publication: 2022 Jul 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Pergamon In Cooperation With The Reproductive Toxicology Center Country of Publication: United States NLM ID: 8803591 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1708 (Electronic) Linking ISSN: 08906238 NLM ISO Abbreviation: Reprod Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Caffeine*/toxicity , Prenatal Exposure Delayed Effects*/metabolism, Animals ; Brain/metabolism ; Female ; Humans ; Lactation ; Male ; Mice ; Pregnancy ; Water/metabolism

المؤلفون: Magenis ML; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Damiani AP; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., de Bem Silveira G; Laboratory of Experimental Pathophysiology, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Dagostin LS; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., de Marcos PS; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., de Souza E; Course of Biomedicine, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., de Roch Casagrande L; Laboratory of Experimental Pathophysiology, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Longaretti LM; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Silveira PCL; Laboratory of Experimental Pathophysiology, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., de Andrade VM; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil.

المصدر: Journal of developmental origins of health and disease [J Dev Orig Health Dis] 2022 Aug; Vol. 13 (4), pp. 441-454. Date of Electronic Publication: 2021 Sep 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cambridge University Press Country of Publication: England NLM ID: 101517692 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2040-1752 (Electronic) Linking ISSN: 20401744 NLM ISO Abbreviation: J Dev Orig Health Dis Subsets: MEDLINE

مواضيع طبية MeSH: Insulin Resistance* , Metabolic Diseases* , Prenatal Exposure Delayed Effects*/metabolism, Animals ; Breast Feeding ; Female ; Fructose/adverse effects ; Humans ; Lactation ; Male ; Mice ; Pregnancy

المؤلفون: Damiani AP; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Magenis ML; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Dagostin LS; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Beretta ÂCDL; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Sarter RJ; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Longaretti LM; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Monteiro IO; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil., Andrade VM; Laboratory of Translational Biomedicine, Graduate Program of Health Sciences, University of Southern Santa Catarina - UNESC, Criciúma, SC, Brazil. Electronic address: vmoraesdeandrade@yahoo.com.br.

المصدر: Mutation research [Mutat Res] 2022 Jul-Dec; Vol. 825, pp. 111796. Date of Electronic Publication: 2022 Aug 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0400763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-135X (Electronic) Linking ISSN: 00275107 NLM ISO Abbreviation: Mutat Res Subsets: MEDLINE

مواضيع طبية MeSH: Alkylating Agents*/toxicity , DNA Damage*, Mice ; Bees ; Animals ; Fatty Acids/pharmacology ; Comet Assay ; Methyl Methanesulfonate/toxicity ; Mutagens/toxicity

المؤلفون: Macan TP; Translational Biomedicine Laboratory, Graduate Program of Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, Brazil.; Department of Environmental Health, National Institute of Health Dr. Ricardo Jorge, Porto, Portugal., de Amorim TA; Translational Biomedicine Laboratory, Graduate Program of Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, Brazil., Damiani AP; Translational Biomedicine Laboratory, Graduate Program of Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, Brazil., Beretta ÂCDL; Translational Biomedicine Laboratory, Graduate Program of Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, Brazil., Magenis ML; Translational Biomedicine Laboratory, Graduate Program of Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, Brazil., Vilela TC; Translational Biomedicine Laboratory, Graduate Program of Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, Brazil., Teixeira JP; Department of Environmental Health, National Institute of Health Dr. Ricardo Jorge, Porto, Portugal., Andrade VM; Translational Biomedicine Laboratory, Graduate Program of Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, Brazil.

المصدر: Drug and chemical toxicology [Drug Chem Toxicol] 2022 May; Vol. 45 (3), pp. 1066-1072. Date of Electronic Publication: 2020 Aug 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Group Country of Publication: United States NLM ID: 7801723 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6014 (Electronic) Linking ISSN: 01480545 NLM ISO Abbreviation: Drug Chem Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Bertholletia* , Diabetes Mellitus, Type 2* , Selenium*/pharmacology, Humans ; Hydrogen Peroxide/pharmacology ; Oxidative Stress

المؤلفون: Magenis ML; Universidade do Extremo Sul Catarinense, Brazil., de Faveri W; Universidade do Extremo Sul Catarinense, Brazil., Castro K; Universidade Federal do Rio Grande do Sul, Brazil., Forte GC; Faculdades Integradas Machado de Assis, Brazil., Grande AJ; Universidade Estadual de Mato Grosso do Sul, Brazil., Perry IS; Hospital de Clinicas de Porto Alegre (HCPA/UFRGS), Brazil.

المصدر: Journal of intellectual disabilities : JOID [J Intellect Disabil] 2022 Mar; Vol. 26 (1), pp. 244-263. Date of Electronic Publication: 2020 Nov 25.

نوع المنشور: Journal Article; Systematic Review

بيانات الدورية: Publisher: SAGE Publications Country of Publication: England NLM ID: 101229024 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-6309 (Electronic) Linking ISSN: 17446295 NLM ISO Abbreviation: J Intellect Disabil Subsets: MEDLINE

مواضيع طبية MeSH: Down Syndrome* , Intellectual Disability*, Breast Feeding ; Child ; Female ; Humans ; Infant ; Infant, Newborn

المؤلفون: Magenis ML; Laboratory of Translational Biomedicine, University of Southern Santa Catarina, UNESC, Criciúma, SC, Brazil., Damiani AP; Laboratory of Translational Biomedicine, University of Southern Santa Catarina, UNESC, Criciúma, SC, Brazil., de Marcos PS; Laboratory of Translational Biomedicine, University of Southern Santa Catarina, UNESC, Criciúma, SC, Brazil., de Pieri E; Laboratory of Translational Pathophysiology, University of Southern Santa Catarina, UNESC, Criciúma, SC, Brazil., de Souza E; Course of Biomedicine, Graduate Program of Health Sciences, Department of Health Sciences, University of Southern Santa Catarina, UNESC, Criciúma, SC, Brazil., Vilela TC; Laboratory of Translational Biomedicine, University of Southern Santa Catarina, UNESC, Criciúma, SC, Brazil., de Andrade VM; Laboratory of Translational Biomedicine, University of Southern Santa Catarina, UNESC, Criciúma, SC, Brazil.

المصدر: Mutagenesis [Mutagenesis] 2020 Mar 27; Vol. 35 (2), pp. 179-187.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 8707812 Publication Model: Print Cited Medium: Internet ISSN: 1464-3804 (Electronic) Linking ISSN: 02678357 NLM ISO Abbreviation: Mutagenesis Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage/*drug effects , Fructose/*adverse effects , Hyperglycemia/*genetics , Pregnancy Complications/*genetics, Animals ; DNA Damage/genetics ; Disease Models, Animal ; Female ; Fructose/pharmacology ; Humans ; Hyperglycemia/chemically induced ; Hyperglycemia/metabolism ; Hyperglycemia/pathology ; Lactation/drug effects ; Mice ; Micronucleus Tests ; Pregnancy ; Pregnancy Complications/chemically induced ; Pregnancy Complications/metabolism ; Pregnancy Complications/pathology ; Reactive Oxygen Species/metabolism