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المؤلفون: Maini Rekdal V; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, United States., Nol Bernadino P; Department of Chemistry and Molecular Biology, University of California, Irvine, Irvine, United States.; Department of Chemistry and Molecular Biochemistry, University of California, Irvine, Irvine, United States., Luescher MU; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, United States., Kiamehr S; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, United States., Le C; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, United States., Bisanz JE; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, United States., Turnbaugh PJ; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, United States.; Chan Zuckerberg Biohub, San Francisco, United States., Bess EN; Department of Chemistry and Molecular Biology, University of California, Irvine, Irvine, United States.; Department of Chemistry and Molecular Biochemistry, University of California, Irvine, Irvine, United States., Balskus EP; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, United States.

المصدر: ELife [Elife] 2020 Feb 18; Vol. 9. Date of Electronic Publication: 2020 Feb 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Diet* , Gastrointestinal Microbiome*, Catechols/*metabolism , Enzymes/*metabolism , Metalloproteins/*metabolism, Humans

المؤلفون: Maini Rekdal V; Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA., Bess EN; Department of Microbiology and Immunology, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA.; Department of Chemistry, University of California, Irvine, 1102 Natural Sciences 2, Irvine, CA 92617, USA.; Department of Molecular Biology and Biochemistry, University of California, Irvine, 1102 Natural Sciences 2, Irvine, CA 92617, USA., Bisanz JE; Department of Microbiology and Immunology, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA., Turnbaugh PJ; Department of Microbiology and Immunology, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA. balskus@chemistry.harvard.edu peter.turnbaugh@ucsf.edu.; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA., Balskus EP; Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA. balskus@chemistry.harvard.edu peter.turnbaugh@ucsf.edu.

المصدر: Science (New York, N.Y.) [Science] 2019 Jun 14; Vol. 364 (6445).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Gastrointestinal Microbiome*/genetics, Actinobacteria/*enzymology , Antiparkinson Agents/*metabolism , Bacterial Proteins/*metabolism , Enterococcus faecalis/*enzymology , Levodopa/*metabolism , Tyrosine/*analogs & derivatives , Tyrosine Decarboxylase/*metabolism, Actinobacteria/drug effects ; Actinobacteria/genetics ; Animals ; Antiparkinson Agents/administration & dosage ; Bacterial Proteins/antagonists & inhibitors ; Bacterial Proteins/genetics ; Decarboxylation/drug effects ; Dopamine/metabolism ; Enterococcus faecalis/drug effects ; Enterococcus faecalis/genetics ; Genome, Bacterial ; HeLa Cells ; Humans ; Levodopa/administration & dosage ; Male ; Metabolic Networks and Pathways/drug effects ; Mice, Inbred BALB C ; Tyrosine/administration & dosage ; Tyrosine/chemistry ; Tyrosine/pharmacology ; Tyrosine Decarboxylase/antagonists & inhibitors ; Tyrosine Decarboxylase/genetics

المؤلفون: Koppel N; Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA., Maini Rekdal V; Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA., Balskus EP; Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA. balskus@chemistry.harvard.edu.; Broad Institute, Cambridge, MA 02139, USA.

المصدر: Science (New York, N.Y.) [Science] 2017 Jun 23; Vol. 356 (6344).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Bacteria/*metabolism , Gastrointestinal Microbiome/*physiology , Xenobiotics/*metabolism, Bacteria/enzymology ; Bacteria/genetics ; Environmental Pollutants/chemistry ; Environmental Pollutants/metabolism ; Food ; Humans ; Pharmaceutical Preparations/chemistry ; Pharmaceutical Preparations/metabolism ; Research/trends ; Xenobiotics/chemistry