المؤلفون: Jacob C. Zbesko, Thuy-Vi V. Nguyen, Tao Yang, Jennifer Beischel Frye, Omar Hussain, Megan Hayes, Amanda Chung, W. Anthony Day, Kristina Stepanovic, Maj Krumberger, Justine Mona, Frank M. Longo, Kristian P. Doyle

المصدر: Neurobiology of Disease, Vol 112, Iss , Pp 63-78 (2018)

مصطلحات موضوعية: Chronic stroke, Neurodegeneration, Liquefactive necrosis, Glial scar, Inflammation, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S096999611830007X; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/cb1f7d33c0e248a5b6dcbf41b912a5fd

المؤلفون: Maj Krumberger, Xingyue Li, Adam G. Kreutzer, Aaron J. Peoples, Anthony G. Nitti, Andrew M. Cunningham, Chelsea R. Jones, Catherine Achorn, Losee L. Ling, Dallas E. Hughes, James S. Nowick

المصدر: The Journal of Organic Chemistry. 88:2214-2220

مصطلحات موضوعية: Organic Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0a2d64a5ff0558a29948aa18a37f16a0
https://doi.org/10.1021/acs.joc.2c02648

المؤلفون: Sheng Zhang, Michael A. Morris, James H Griffin, James S. Nowick, Chelsea Marie T. Parrocha, Maj Krumberger, Adam G. Kreutzer

المصدر: European Journal of Medicinal Chemistry
ChemRxiv
article-version (number) 1
article-version (status) pre

مصطلحات موضوعية: Computer science, medicine.medical_treatment, 01 natural sciences, Software, Catalytic Domain, Drug Discovery, Lung, Coronavirus 3C Proteases, 0303 health sciences, Drug discovery, Chemistry, Experimental validation, General Medicine, Pharmacology and Pharmaceutical Sciences, AutoDock vina, 5.1 Pharmaceuticals, Main protease (M(pro)) inhibitor, Pneumonia & Influenza, Structure-based drug design, Development of treatments and therapeutic interventions, Protein Binding, Molecular modeling tutorial, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Medicinal & Biomolecular Chemistry, Main protease (Mpro) inhibitor, Computational biology, Antiviral Agents, Article, Autodock vina, 03 medical and health sciences, Medicinal and Biomolecular Chemistry, medicine, Humans, Structure-based drug design (SBDD), Protease Inhibitors, UCSF Chimera, 030304 developmental biology, Pharmacology, Protease, Binding Sites, Drug candidate, 010405 organic chemistry, business.industry, SARS-CoV-2, Organic Chemistry, COVID-19, Main protease (M-pro) inhibitor, Pneumonia, 0104 chemical sciences, COVID-19 Drug Treatment, Emerging Infectious Diseases, Good Health and Well Being, Drug Design, Structure based, Design process, Generic health relevance, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d25034764bebe564ad8c85714aacc7
https://escholarship.org/uc/item/7mj1k9tq

المؤلفون: Michael A. Morris, Chelsea Marie T. Parrocha, Carter T. Butts, Maj Krumberger, Gretchen Guaglianone, Adam G. Kreutzer, James S. Nowick, Elizabeth M. Diessner

المصدر: European Journal of Medicinal Chemistry

مصطلحات موضوعية: Stereochemistry, Protein Conformation, Medicinal & Biomolecular Chemistry, medicine.medical_treatment, cyclic peptide inhibitor, Molecular Dynamics Simulation, Cleavage (embryo), cyclophane, 01 natural sciences, Peptides, Cyclic, Article, Medicinal and Biomolecular Chemistry, 03 medical and health sciences, Protein structure, Drug Discovery, medicine, Humans, Protease Inhibitors, Coronavirus 3C Proteases, Cyclic peptide inhibitor, Cyclophane, 030304 developmental biology, Pharmacology, chemistry.chemical_classification, Cyclic, 0303 health sciences, Protease, biology, 010405 organic chemistry, SARS-CoV-2, Organic Chemistry, Active site, COVID-19, Pharmacology and Pharmaceutical Sciences, General Medicine, Cyclic peptide, 0104 chemical sciences, Molecular Docking Simulation, Emerging Infectious Diseases, Enzyme, HEK293 Cells, chemistry, Docking (molecular), main protease, Main protease, Drug Design, biology.protein, Peptides, Linker

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8822a5694e3b277154fc0e02b518174a
https://pubmed.ncbi.nlm.nih.gov/34023738

المؤلفون: Gretchen Guaglianone, Maj Krumberger, James S. Nowick, Chelsea Marie T. Parrocha, Adam G. Kreutzer, Michael A. Morris

مصطلحات موضوعية: chemistry.chemical_classification, Protease, Biochemistry, Chemistry, medicine.medical_treatment, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), medicine, Structure based, Cleavage (embryo), In vitro, Cyclic peptide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3e4b35a8cef53b4f43528c14ed2b9222
https://doi.org/10.1101/2020.08.03.234872

المؤلفون: Kristian P. Doyle, Jennifer B. Frye, W. Anthony Day, Frank M. Longo, Justine Mona, Megan Hayes, Tao Yang, Omar Khadeer Hussain, Amanda Chung, Thuy-Vi V. Nguyen, Kristina Stepanovic, Maj Krumberger, Jacob C. Zbesko

المصدر: Neurobiology of Disease, Vol 112, Iss, Pp 63-78 (2018)

مصطلحات موضوعية: Male, 0301 basic medicine, Pathology, medicine.medical_specialty, Central nervous system, Liquefactive necrosis, Scars, Article, Glial scar, lcsh:RC321-571, Cicatrix, Mice, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Humans, Gliosis, Neurodegeneration, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Stroke, Cells, Cultured, Inflammation, Mice, Inbred BALB C, Cerebral infarction, business.industry, Brain, Cerebral Infarction, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Neurology, Chronic stroke, Neuroglia, medicine.symptom, business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2587a45dafdb9d5ac4bbb83a7af488
https://doi.org/10.1016/j.nbd.2018.01.007