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1دورية أكاديمية
المؤلفون: Saiful Islam, Theodosia Teo, Malika Kumarasiri, Martin Slater, Jennifer H. Martin, Shudong Wang, Richard Head
المصدر: Pharmaceuticals, Vol 15, Iss 10, p 1186 (2022)
مصطلحات موضوعية: repurposing, kinase, cancer, rilpivirine, virtual screening, Medicine, Pharmacy and materia medica, RS1-441
وصف الملف: electronic resource
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المؤلفون: Saiful, Islam, Theodosia, Teo, Malika, Kumarasiri, Martin, Slater, Jennifer H, Martin, Shudong, Wang, Richard, Head
المصدر: Pharmaceuticals (Basel, Switzerland). 15(10)
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المؤلفون: Laychiluh Bantie, Saiful Islam, Malika Kumarasiri, Solomon Tadesse, Benjamin Noll, Robert W. Milne, Khamis Tomusange, Ge Zhu, Nataliya Bykovska, Mingfeng Yu, Shudong Wang, Frankie Lam, Peng Li
المصدر: British Journal of Pharmacology. 175:2399-2413
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, biology, Chemistry, Drug discovery, Cyclin-dependent kinase 4, Kinase, Cell cycle, 03 medical and health sciences, 030104 developmental biology, Cyclin-dependent kinase, Cancer cell, biology.protein, Cancer research, Cyclin-dependent kinase 6, E2F
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المؤلفون: Malika Kumarasiri, Mingfeng Yu, Stephen Philip, Theodosia Teo, Shudong Wang
المصدر: Journal of Medicinal Chemistry. 61:5073-5092
مصطلحات موضوعية: 0301 basic medicine, Oncogene, Chemistry, Kinase, medicine.disease_cause, 03 medical and health sciences, 030104 developmental biology, Mediator, Transcription (biology), Drug Discovery, Cancer research, medicine, Molecular Medicine, Cyclin-dependent kinase 8, Carcinogenesis, Transcription factor, Gene
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المؤلفون: Malika Kumarasiri, Mingfeng Yu, Solomon Tadesse, Robert W. Milne, Jimma L Lenjisa, Shudong Wang, Hugo Albrecht, Nishat Zareen Khair
المساهمون: Lenjisa, Jimma Likisa, Tadesse, Solomon, Khair, Nishat Zareen, Kumarasiri, Malika, Yu, Mingfeng, Albrecht, Hugo, Milne, Robert, Wang, Shudong
المصدر: Future Medicinal Chemistry. 9:1939-1962
مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, CDK, Druggability, Cancer therapy, Antineoplastic Agents, p35, targeted cancer therapy, Structure-Activity Relationship, 03 medical and health sciences, Cancer stem cell, Cyclin-dependent kinase, Drug Discovery, medicine, Humans, cancer, Molecular Targeted Therapy, Pharmacology, Molecular Structure, biology, Kinase, Cyclin-dependent kinase 5, Cell Cycle, Cancer, Cyclin-Dependent Kinase 5, medicine.disease, p25, Cancer treatment, 030104 developmental biology, nervous system, Immunology, Neoplastic Stem Cells, biology.protein, Cancer research, Molecular Medicine, cancer hallmarks, CDK5 inhibitors, Protein Binding
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المؤلفون: Peng Li, Aik Wye Goh, Malika Kumarasiri, Shudong Wang, Yi Long, Mingfeng Yu, Saiful Islam
المساهمون: Long, Yi, Yu, Mingfeng, Li, Peng, Islam, Saiful, Goh, Aik Wye, Kumarasiri, Malika, Wang, Shudong
المصدر: Bioorganic & Medicinal Chemistry Letters. 26:5674-5678
مصطلحات موضوعية: 0301 basic medicine, Cell cycle checkpoint, kinase inhibitor, Clinical Biochemistry, non-ATP competitive inhibition, Pharmaceutical Science, Antineoplastic Agents, Apoptosis, Hydrocarbons, Aromatic, Biochemistry, Sulfone, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, Neoplasms, Drug Discovery, Humans, Structure–activity relationship, Sulfones, Molecular Biology, Cell Proliferation, Cell growth, Organic Chemistry, Cell Cycle Checkpoints, anti-cancer agents, 030104 developmental biology, chemistry, Cell culture, 030220 oncology & carcinogenesis, polo-like kinase 1, Cancer cell, Molecular Medicine, ras-driven signaling pathways, Lead compound
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المؤلفون: Hugo Albrecht, Solomon Tadesse, Matthew J. Sykes, Nishat Zareen Khair, Shudong Wang, Malika Kumarasiri, Jimma L Lenjisa, Robert W. Milne, Laychiluh B. Mekonnen, Sarah Diab, Man-jun Li, Sunita K.C. Basnet
المساهمون: Khair, Nishat Z, Lenjisa, Jimma L, Tadesse, Solomon, Kumarasiri, Malika, Basnet, Sunita KC, Mekonnen, Laychiluh B, Li, Manjun, Diab, Sarah, Sykes, Matthew J, Albrecht, Hugo, Milne, Robert, Wang, Shudong
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: In silico, CDK5, Computational biology, 01 natural sciences, Biochemistry, AML, Drug Discovery, Virtual screening, biology, 010405 organic chemistry, Kinase, Chemistry, Drug discovery, Cyclin-dependent kinase 5, Organic Chemistry, Cyclin-dependent kinase 2, apoptosis, Myeloid leukemia, Cell cycle, virtual screening, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, nervous system, biology.protein, cell cycle, CDK5 inhibitors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::683ff5cd65cd9dc6bcc6078b1453b846
https://europepmc.org/articles/PMC6511963/ -
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المؤلفون: Bich Thuy Le, Mingfeng Yu, Malika Kumarasiri, Shudong Wang, Solomon Tadesse
المساهمون: Tadesse, Solomon, Yu, Mingfeng, Kumarasiri, Malika, Le, Bich Thuy, Wang, Shudong
المصدر: Cell Cycle. 14:3220-3230
مصطلحات موضوعية: Antineoplastic Agents, Review, Biology, Crystallography, X-Ray, targeted cancer therapy, Protein Structure, Secondary, drug discovery, Drug Delivery Systems, Cyclin-dependent kinase, Neoplasms, medicine, Animals, Humans, Molecular Biology, inhibitor design, Drug discovery, oncogene and tumor suppressor, Cell Cycle, Cancer, Cyclin-Dependent Kinase 6, Cell Biology, Cell cycle, medicine.disease, Cell biology, cyclin-dependent kinase, Drug development, Cancer cell, biology.protein, cell cycle, Cyclin-dependent kinase 6, Biological regulation, Developmental Biology
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المؤلفون: Daniel R. Marous, Malika Kumarasiri, Kiran V. Mahasenan, Juan A. Hermoso, Shahriar Mobashery, Jed F. Fisher, David A. Dik, Enrico Speri, Byungjin Byun
المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Digital.CSIC. Repositorio Institucional del CSIC
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Scientific Reportsمصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Stereochemistry, lcsh:Medicine, Flagellum, 010402 general chemistry, Cleavage (embryo), medicine.disease_cause, 01 natural sciences, Article, Bacterial cell structure, Cell wall, 03 medical and health sciences, chemistry.chemical_compound, Cell Wall, Catalytic Domain, Escherichia coli, medicine, lcsh:Science, Type VI secretion system, Multidisciplinary, Escherichia coli Proteins, lcsh:R, Acetal, Glycosyltransferases, Type VI Secretion Systems, 3. Good health, 0104 chemical sciences, 030104 developmental biology, chemistry, Lytic cycle, lcsh:Q
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المؤلفون: Stephen, Philip, Malika, Kumarasiri, Theodosia, Teo, Mingfeng, Yu, Shudong, Wang
المصدر: Journal of medicinal chemistry. 61(12)
مصطلحات موضوعية: Male, Neoplasms, Cytokines, Humans, Antineoplastic Agents, Tumor Escape, Molecular Targeted Therapy, Phosphorylation, Cyclin-Dependent Kinase 8, Protein Kinase Inhibitors, Transcription Factors