المؤلفون: Ruperto N, Brunner HI, Ramanan AV, Horneff G, Cuttica R, Henrickson M, Anton J, Boteanu AL, Penades IC, Minden K, Schmeling H, Hufnagel M, Weiss JE, Pardeo M, Nanda K, Roth J, Rubio-Pérez N, Hsu JC, Wimalasundera S, Wells C, Bharucha K, Douglass W, Bao M, Mallalieu NL, Martini A, Lovell D, De Benedetti F, Paediatric Rheumatology INternational Trials Organisation (PRINTO) and the Pedia

المصدر: Rheumatology
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Rheumatology (Oxford, England)
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe

مصطلحات موضوعية: musculoskeletal diseases, Autoinflammatory conditions, Biological therapies, Cytokines and inflammatory mediators, Inflammation, Juvenile Idiopathic Arthritis, biologic therapies, genetic structures, immune system diseases, inflammation, autoinflammatory conditions, cytokines and inflammatory mediators, skin and connective tissue diseases, juvenile idiopathic arthritis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1a314eb0bd4732c03544a4a95918677d
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=18829

المؤلفون: Mallalieu NL, Wimalasundera S, Hsu JC, Douglass W, Wells C, Penades IC, Cuttica R, Huppertz HI, Joos R, Kimura Y, Milojevic D, Rosenkranz M, Schikler K, Constantin T, Wouters C

المصدر: PEDIATRIC RHEUMATOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

مصطلحات موضوعية: Biological therapy, Inflammation, Juvenile idiopathic arthritis, Pharmacokinetics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::33b69f29ac7ee0210c11a3f18289cdf1
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=11041

المؤلفون: Mallalieu NL; Roche Innovation Center, New York, New York, USA., Winter E; Roche Innovation Center, New York, New York, USA., Fettner S; Roche Innovation Center, New York, New York, USA., Patel K; Roche Innovation Center, Welwyn, United Kingdom., Zwanziger E; Roche Innovation Center, Basel, Switzerland., Attley G; Roche Innovation Center, New York, New York, USA., Rodriguez I; Roche Innovation Center, New York, New York, USA., Kano A; Meiji Seika Pharma Co., Ltd., Tokyo, Japan., Salama SM; Fedora Pharmaceuticals, Inc., Edmonton, Alberta, Canada., Bentley D; Roche Innovation Center, Welwyn, United Kingdom., Geretti AM; Roche Innovation Center, Basel, Switzerland anna_maria.geretti@roche.com.; Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom.

المصدر: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2020 Apr 21; Vol. 64 (5). Date of Electronic Publication: 2020 Apr 21 (Print Publication: 2020).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Bacterial Agents/*adverse effects , Anti-Bacterial Agents/*pharmacokinetics , Azabicyclo Compounds/*adverse effects , Azabicyclo Compounds/*pharmacokinetics , Lactams/*adverse effects , Lactams/*pharmacokinetics , Meropenem/*adverse effects , Meropenem/*pharmacokinetics , beta-Lactamase Inhibitors/*adverse effects , beta-Lactamase Inhibitors/*pharmacokinetics, Adolescent ; Adult ; Aged ; Area Under Curve ; Dose-Response Relationship, Drug ; Double-Blind Method ; Drug Combinations ; Drug Interactions ; Electrocardiography/drug effects ; Female ; Humans ; Male ; Middle Aged ; Patient Safety ; Young Adult

المؤلفون: Fettner S; a Roche Innovation Center , New York , NY , USA., Mela C; b Roche Products Ltd ., Welwyn Garden City , UK., Wildenhahn F; c F. Hoffmann-La Roche Ltd ., Basel , Switzerland., Tavanti M; c F. Hoffmann-La Roche Ltd ., Basel , Switzerland., Wells C; b Roche Products Ltd ., Welwyn Garden City , UK., Douglass W; b Roche Products Ltd ., Welwyn Garden City , UK., Mallalieu NL; a Roche Innovation Center , New York , NY , USA.

المصدر: Expert opinion on drug delivery [Expert Opin Drug Deliv] 2019 May; Vol. 16 (5), pp. 551-561. Date of Electronic Publication: 2019 May 02.

نوع المنشور: Clinical Trial, Phase IV; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101228421 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7593 (Electronic) Linking ISSN: 17425247 NLM ISO Abbreviation: Expert Opin Drug Deliv Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Monoclonal, Humanized/*administration & dosage , Arthritis, Rheumatoid/*drug therapy , Receptors, Interleukin-6/*antagonists & inhibitors, Adult ; Aged ; Antibodies, Monoclonal, Humanized/pharmacokinetics ; Cross-Over Studies ; Female ; Humans ; Injections, Subcutaneous ; Male ; Middle Aged ; Syringes ; Therapeutic Equivalency

المؤلفون: Cosson V; Pharmaceutical Sciences Clinical Pharmacology, Roche Innovation Center Basel, F. Hoffmann-La Roche, Basel, Switzerland., Schaedeli-Stark F; Pharmaceutical Sciences Clinical Pharmacology, Roche Innovation Center Basel, F. Hoffmann-La Roche, Basel, Switzerland., Arab-Alameddine M; Pharmaceutical Sciences Clinical Pharmacology, Roche Innovation Center Basel, F. Hoffmann-La Roche, Basel, Switzerland., Chavanne C; Pharmaceutical Sciences Clinical Pharmacology, Roche Innovation Center Basel, F. Hoffmann-La Roche, Basel, Switzerland., Guerini E; Pharmaceutical Sciences Clinical Pharmacology, Roche Innovation Center Basel, F. Hoffmann-La Roche, Basel, Switzerland., Derks M; Pharmaceutical Sciences Clinical Pharmacology, Roche Innovation Center Welwyn, Roche Products, Welwyn, UK., Mallalieu NL; Pharmaceutical Sciences Clinical Pharmacology, Roche Innovation Center New York, F. Hoffmann-La Roche, New York, New York, USA.

المصدر: Clinical and translational science [Clin Transl Sci] 2018 Sep; Vol. 11 (5), pp. 523-531. Date of Electronic Publication: 2018 Jun 27.

نوع المنشور: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci

مواضيع طبية MeSH: Models, Biological*, Depressive Disorder, Major/*drug therapy , Dizziness/*chemically induced , Imidazoles/*adverse effects , Imidazoles/*pharmacokinetics , Pyridines/*adverse effects , Pyridines/*pharmacokinetics , Receptor, Metabotropic Glutamate 5/*metabolism, Allosteric Regulation ; Humans ; Imidazoles/therapeutic use ; Pyridines/therapeutic use

المؤلفون: Burmester GR; Department of Rheumatology and Clinical Immunology, Charité-University Medicine Berlin, Free University and Humboldt University of Berlin, Berlin, Germany., Choy E; Cardiff University, Cardiff, UK., Kivitz A; Altoona Center for Clinical Research, Duncansville, Pennsylvania, USA., Ogata A; Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine, Osaka, Japan.; Division of Allergy, Rheumatology and Connective Tissue Diseases, Department of Internal Medicine, NTT West Osaka Hospital, Osaka, Japan., Bao M; Genentech, Inc., South San Francisco, California, USA., Nomura A; Chugai Pharmaceutical Co., Ltd., Tokyo, Japan., Lacey S; Roche Products Limited, Welwyn Garden City, UK., Pei J; Genentech, Inc., South San Francisco, California, USA., Reiss W; Genentech, Inc., South San Francisco, California, USA., Pethoe-Schramm A; F. Hoffmann-La Roche Ltd, Basel, Switzerland., Mallalieu NL; Roche Innovation Center, New York, New York, USA., Wallace T; Genentech, Inc., South San Francisco, California, USA., Michalska M; Genentech, Inc., South San Francisco, California, USA., Birnboeck H; Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland., Stubenrauch K; Roche Pharma Research and Early Development, Roche Innovation Center, Munich, Germany., Genovese MC; Division of Immunology and Rheumatology, Stanford University Medical Center, Palo Alto, California, USA.

المصدر: Annals of the rheumatic diseases [Ann Rheum Dis] 2017 Jun; Vol. 76 (6), pp. 1078-1085. Date of Electronic Publication: 2016 Dec 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BMJ Country of Publication: England NLM ID: 0372355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2060 (Electronic) Linking ISSN: 00034967 NLM ISO Abbreviation: Ann Rheum Dis Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies/*blood , Antibodies, Monoclonal, Humanized/*immunology , Arthritis, Rheumatoid/*drug therapy , Drug Hypersensitivity/*immunology, Administration, Intravenous ; Anaphylaxis/chemically induced ; Antibodies, Monoclonal, Humanized/pharmacokinetics ; Antibodies, Monoclonal, Humanized/therapeutic use ; Clinical Trials, Phase III as Topic ; Drug Therapy, Combination ; Humans ; Injections, Subcutaneous

المؤلفون: Guerini E; a Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel , Basel , Switzerland and., Schadt S; a Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel , Basel , Switzerland and., Greig G; a Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel , Basel , Switzerland and., Haas R; a Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel , Basel , Switzerland and., Husser C; a Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel , Basel , Switzerland and., Zell M; a Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel , Basel , Switzerland and., Funk C; a Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel , Basel , Switzerland and., Hartung T; a Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel , Basel , Switzerland and., Gloge A; a Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel , Basel , Switzerland and., Mallalieu NL; b Roche Pharmaceutical Research and Early Development, Roche Innovation Center NYC , NY , USA.

المصدر: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2017 Feb; Vol. 47 (2), pp. 144-153. Date of Electronic Publication: 2016 Apr 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE

مواضيع طبية MeSH: Imidazoles/*pharmacokinetics , Pyridines/*pharmacokinetics, Administration, Oral ; Area Under Curve ; Half-Life ; Humans

المؤلفون: Fowler S; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Guerini E; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Qiu N; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Cleary Y; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Parrott N; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Greig G; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Mallalieu NL; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland navita_l.mallalieu@roche.com.

المصدر: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2017 Jan; Vol. 360 (1), pp. 164-173. Date of Electronic Publication: 2016 Nov 07.

نوع المنشور: Clinical Trial; Journal Article

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0376362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0103 (Electronic) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE

مواضيع طبية MeSH: Cytochrome P-450 Enzyme System/*metabolism , Imidazoles/*metabolism , Imidazoles/*pharmacology , Pyridines/*metabolism , Pyridines/*pharmacology, Adult ; Aged ; Carbamazepine/pharmacology ; Drug Interactions ; Female ; Fluvoxamine/pharmacology ; Humans ; Ketoconazole/pharmacology ; Kinetics ; Male ; Middle Aged ; Oxidation-Reduction ; Young Adult

المؤلفون: Brennan BJ; Hoffmann-La Roche Inc., Nutley, NJ, USA., Lemenuel-Diot A; F. Hoffmann-La Roche Ltd, Basel, Switzerland., Snoeck E; SGS Exprimo NV, Mechelen, Belgium and., McKenna M; Roche Products Ltd, Welwyn, UK., Solsky J; Hoffmann-La Roche Inc., Nutley, NJ, USA., Wat C; Roche Products Ltd, Welwyn, UK., Mallalieu NL; Hoffmann-La Roche Inc., Nutley, NJ, USA.

المصدر: British journal of clinical pharmacology [Br J Clin Pharmacol] 2016 Apr; Vol. 81 (4), pp. 658-66. Date of Electronic Publication: 2016 Jan 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Drug Dosage Calculations* , Models, Biological*, Antiviral Agents/*administration & dosage , Hepatitis C/*drug therapy , Interferon-alpha/*administration & dosage , Polyethylene Glycols/*administration & dosage, Adolescent ; Adult ; Antiviral Agents/pharmacokinetics ; Antiviral Agents/therapeutic use ; Body Surface Area ; Child ; Child, Preschool ; Clinical Trials as Topic ; Computer Simulation ; Drug Administration Schedule ; Humans ; Interferon-alpha/pharmacokinetics ; Interferon-alpha/therapeutic use ; Polyethylene Glycols/pharmacokinetics ; Polyethylene Glycols/therapeutic use ; Predictive Value of Tests ; Recombinant Proteins/administration & dosage ; Recombinant Proteins/pharmacokinetics ; Recombinant Proteins/therapeutic use ; Tissue Distribution ; Young Adult

المؤلفون: Mallalieu NL; Hoffmann-La Roche Inc, Nutley, New Jersey. Electronic address: navita_l.mallalieu@roche.com., Rahimy MH; Anadys Pharmaceuticals, San Diego, California., Crowley CA; Anadys Pharmaceuticals, San Diego, California., Appleman JR; Anadys Pharmaceuticals, San Diego, California., Smith PF; Hoffmann-La Roche Inc, Nutley, New Jersey., Freddo JL; Anadys Pharmaceuticals, San Diego, California.

المصدر: Clinical therapeutics [Clin Ther] 2014 Dec 01; Vol. 36 (12), pp. 2047-2063.e3. Date of Electronic Publication: 2014 Nov 04.

نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Excerpta Medica Country of Publication: United States NLM ID: 7706726 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-114X (Electronic) Linking ISSN: 01492918 NLM ISO Abbreviation: Clin Ther Subsets: MEDLINE

مواضيع طبية MeSH: Antiviral Agents/*pharmacology , Benzothiadiazines/*pharmacology , Hepatitis C, Chronic/*drug therapy , Quinolones/*pharmacology, Adolescent ; Adult ; Antiviral Agents/pharmacokinetics ; Antiviral Agents/therapeutic use ; Benzothiadiazines/pharmacokinetics ; Benzothiadiazines/therapeutic use ; Dose-Response Relationship, Drug ; Double-Blind Method ; Female ; Half-Life ; Hepacivirus ; Humans ; Male ; Middle Aged ; Quinolones/pharmacokinetics ; Quinolones/therapeutic use ; Young Adult