المؤلفون: Biljana Arsic, Jill Barber, Ana Cikos, Manikandan Kadirvel, Emilija Kostic, Andrew J. McBain, Jelena Milicevic, Angela Oates, Andrew Regan

المصدر: Molecules, Vol 27, Iss 21, p 7280 (2022)

مصطلحات موضوعية: macrolides, bacteria, 2D ROESY NMR, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/21/7280; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/6e59cbb94b5942ef9cc0601635fdd2a8

المؤلفون: Rok Krašovec, Roman V. Belavkin, John A.D. Aston, Alastair Channon, Elizabeth Aston, Bharat M. Rash, Manikandan Kadirvel, Sarah Forbes, Christopher G. Knight

المصدر: Microbial Cell, Vol 1, Iss 7, Pp 250-252 (2014)

مصطلحات موضوعية: evolution, mutagenesis, fluctuation test, autoinducer 2, autoinducer 3, stress-induced mutagenesis, DNA methylation, optimal control, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://microbialcell.com/researcharticles/where-antibiotic-resistance-mutations-meet-quorum-sensing/; https://doaj.org/toc/2311-2638

URL الوصول: https://doaj.org/article/a2914fa396a4493e8794be5d25869947

المؤلفون: Mai A. Elhemely, Asma A. Belgath, Sherihan El-Sayed, Kepa K. Burusco, Manikandan Kadirvel, Annalisa Tirella, Katherine Finegan, Richard A. Bryce, Ian J. Stratford, Sally Freeman

المصدر: Journal of Medicinal Chemistry. 65:4783-4797

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ff7960c4d8e54664eab5163e9be558
https://doi.org/10.1021/acs.jmedchem.1c01936

المؤلفون: Thomas J. Smith, Paula G. Chirila, L Jaques, Melissa M. Lacey, KL Parkin, Sarah Forbes, Manikandan Kadirvel, EL Henly, Karl Norris, K Rawson, Christopher J. Whiteoak, N Zoulias

مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), 030106 microbiology, Microbial Sensitivity Tests, medicine.disease_cause, Microbiology, 03 medical and health sciences, Gene expression, medicine, Humans, Uropathogenic Escherichia coli, Pharmacology (medical), Gene, Escherichia coli, Pharmacology, Regulation of gene expression, biology, Biofilm, Quorum Sensing, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, Anti-Bacterial Agents, Galleria mellonella, Bacterial adhesin, Quorum sensing, 030104 developmental biology, Infectious Diseases, Biofilms, Urinary Tract Infections

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82529ba679d770e18013f92be345d892
https://shura.shu.ac.uk/28017/10/Forbes-ImpactLong-term(AM).pdf

المؤلفون: Manikandan Kadirvel, Sally Freeman, Gavin Brown, Déborah Cardoso

المساهمون: Brown, Gavin [0000-0003-4443-0785], Apollo - University of Cambridge Repository

المصدر: Journal of Radioanalytical and Nuclear Chemistry
Kadirvel, M, Cardoso, D, Freeman, S & Brown, G 2018, ' Radiosynthesis and reactivity of N-[11C]methyl carbamoylimidazole ', Journal of Radioanalytical and Nuclear Chemistry, vol. 317, no. 2 . https://doi.org/10.1007/s10967-018-5948-4

مصطلحات موضوعية: Health, Toxicology and Mutagenesis, Methyl isocyanate, 010402 general chemistry, 01 natural sciences, Medicinal chemistry, Article, Analytical Chemistry, chemistry.chemical_compound, Radiology, Nuclear Medicine and imaging, Reactivity (chemistry), Chemical route, Spectroscopy, 11C, Radiochemistry, 010405 organic chemistry, Radiosynthesis, Synthon, Public Health, Environmental and Occupational Health, Pet imaging, Pollution, 0104 chemical sciences, PET, Nuclear Energy and Engineering, chemistry, Yield (chemistry), Carbamoylation, Methyl iodide

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf58bff3c674767fe5e56cd74f88680
http://europepmc.org/articles/PMC6061098

المؤلفون: Sally Freeman, Izzeddin Alsalahat, Manikandan Kadirvel, Ian J. Stratford, Soraya Alnabulsi, Buthaina Hussein, Richard A. Bryce, Elham Santina, Rachael N. Magwaza, Alex G. Baldwin, Ilaria Russo, Carl H. Schwalbe

المصدر: Alnabulsi, S, Hussein, B, Santina, E, Alsalahat, I, Kadirvel, M, Magwaza, R N, Bryce, R A, Schwalbe, C H, Baldwin, A G, Russo, I, Stratford, I J & Freeman, S 2018, ' Evaluation of analogues of furan-amidines as inhibitors of NQO2 ', Bioorganic & medicinal chemistry letters . https://doi.org/10.1016/j.bmcl.2018.03.025

مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Plasmodium falciparum, Clinical Biochemistry, Amidines, Pharmaceutical Science, Thiophenes, 01 natural sciences, Biochemistry, Benzamidine, Amidine, Antimalarials, Structure-Activity Relationship, QH301, 03 medical and health sciences, chemistry.chemical_compound, Furan, Oximes, Drug Discovery, Thiophene, Imidazole, Enzyme Inhibitors, Quinone Reductases, Solubility, Furans, Oxazoles, Molecular Biology, Oxazole, chemistry.chemical_classification, Molecular Structure, 010405 organic chemistry, QH, Organic Chemistry, Imidazoles, 0104 chemical sciences, 030104 developmental biology, Enzyme, chemistry, Molecular Medicine

وصف الملف: application/pdf; application/msword

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1fefe3aeaedbb824fac418a62e2b723
https://doi.org/10.1016/j.bmcl.2018.03.025

المؤلفون: Sally Freeman, Richard A. Bryce, Rachael N. Magwaza, Ian J. Stratford, Balqees Ikhmais, Manikandan Kadirvel, Gavin Halbert, Buthaina Hussein

المصدر: Freeman, S, Stratford, I, Kadirvel, M & Bryce, R 2019, ' Discovery of potent 4-aminoquinoline hydrazone inhibitors of NRH:quinoneoxidoreductase-2 (NQO2) ', European Journal of Medicinal Chemistry . https://doi.org/10.1016/j.ejmech.2019.111649

مصطلحات موضوعية: Models, Molecular, Stereochemistry, Cell Survival, Substituent, Hydrazone, Hydrazide, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, Tumor Cells, Cultured, Humans, Hydrazine (antidepressant), Enzyme Inhibitors, Quinone Reductases, Cytotoxicity, IC50, 030304 developmental biology, Pharmacology, chemistry.chemical_classification, 0303 health sciences, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Organic Chemistry, Hydrazones, NQO2 inhibitors, anticancer, 4-aminoquinoline, hydrazine, ovarian cancer, SKOV-3 cells, TOV-112D cells, CB1954, Active site, General Medicine, 0104 chemical sciences, chemistry, 4-Aminoquinoline, biology.protein, Aminoquinolines

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd6ef829791385f3284d46add7c94a5
https://pubmed.ncbi.nlm.nih.gov/31514018

المؤلفون: Karen A. Nolan, Richard A. Bryce, Constantinos Demonacos, Ian J. Stratford, Sally Freeman, Buthaina Hussein, Amy L. Chadwick, Elena V. Bichenkova, Elham Santina, Ilaria Russo, Manikandan Kadirvel, Soraya Alnabulsi

المصدر: Alnabulsi, S, Santina, E, Russo, I, Hussein, B, Kadirvel, M, Chadwick, A, Bichenkova, E, Bryce, R, Nolan, K, Demonacos, C, Stratford, I & Freeman, S 2016, ' Non-symmetrical furan-amidines as novel leads for the treatment of cancer and malaria ', European Journal of Medicinal Chemistry, vol. 111, pp. 33-45 . https://doi.org/10.1016/j.ejmech.2016.01.022

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Plasmodium, Stereochemistry, Amidines, Antineoplastic Agents, Quinone oxidoreductase, 01 natural sciences, Antimalarials, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Nucleic acid thermodynamics, Parasitic Sensitivity Tests, Furan, Drug Discovery, Journal Article, Humans, Structure–activity relationship, Furans, IC50, Cell Proliferation, Pharmacology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Cell growth, Research Support, Non-U.S. Gov't, Organic Chemistry, General Medicine, Malaria, 0104 chemical sciences, 030104 developmental biology, Enzyme, Drug Screening Assays, Antitumor, DNA

وصف الملف: application/msword

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f400e810cef184cc2586a95fb363f62
https://doi.org/10.1016/j.ejmech.2016.01.022

المؤلفون: Gavin Brown, Nigel Westwood, Michael Green, Sue Siew Chen Chua, Jonathan Lowe, Adam McMahon, Manikandan Kadirvel

المصدر: Green, M, Lowe, J, Kadirvel, M, Mcmahon, A, Westwood, N, Chua, S S C & Brown, G 2017, ' Radiosynthesis of no-carrier-added meta-[124I] iodobenzylguanidine for PET imaging of metastatic neuroblastoma ' Journal of Radioanalytical and Nuclear Chemistry, vol 311, no. 1 . DOI: 10.1007/s10967-016-5073-1
Green, M, Lowe, J, Kadirvel, M, Mcmahon, A, Westwood, N, Chua, S S C & Brown, G 2017, ' Radiosynthesis of no-carrier-added meta-[124I] iodobenzylguanidine for PET imaging of metastatic neuroblastoma ', Journal of Radioanalytical and Nuclear Chemistry, vol. 311, no. 1 . https://doi.org/10.1007/s10967-016-5073-1

مصطلحات موضوعية: Health, Toxicology and Mutagenesis, Metastatic neuroblastoma, No carrier added, Diagnostic accuracy, 030218 nuclear medicine & medical imaging, Analytical Chemistry, Inorganic Chemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Neuroblastoma, medicine, Radiology, Nuclear Medicine and imaging, Spectroscopy, Cancer, medicine.diagnostic_test, business.industry, Radiosynthesis, Public Health, Environmental and Occupational Health, ResearchInstitutes_Networks_Beacons/03/03, Pet imaging, medicine.disease, Pollution, Nuclear Energy and Engineering, chemistry, Positron emission tomography, 030220 oncology & carcinogenesis, Sodium iodide, Nuclear medicine, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898e77cf8ac80eff58c94a19259cf926
https://pure.manchester.ac.uk/ws/files/54096051/art_10.1007_s10967_016_5073_1.pdf

المؤلفون: Gavin Brown, Muhammad Babur, Alison Smigova, Christopher Cawthorne, Kaye J. Williams, Paul Birkket, Manikandan Kadirvel, Emily J. Rowling, Michael Fairclough, Adam McMahon, Sally Freeman

المصدر: Bioorganic & Medicinal Chemistry. 22:341-349

مصطلحات موضوعية: integumentary system, Chemistry, Stereochemistry, organic chemicals, Organic Chemistry, Clinical Biochemistry, Radiosynthesis, Pharmaceutical Science, Halogenation, complex mixtures, Biochemistry, Small molecule, In vitro, chemistry.chemical_compound, Nucleophile, In vivo, Yield (chemistry), Drug Discovery, Molecular Medicine, Molecular Biology, Fluoride, Nuclear chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cb2d029480028deca027fa40e2445bd3
https://doi.org/10.1016/j.bmc.2013.11.019