المؤلفون: Alpizar-Sosa EA; Department of Biosciences, University of Durham, South Road, Durham, DH1 3LE, U.K., Zimbres FM; Department of Biosciences, University of Durham, South Road, Durham, DH1 3LE, U.K., Mantilla BS; Department of Biosciences, University of Durham, South Road, Durham, DH1 3LE, U.K., Dickie EA; School of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, U.K., Wei W; Department of Biosciences, University of Durham, South Road, Durham, DH1 3LE, U.K., Burle-Caldas GA; Department of Biosciences, University of Durham, South Road, Durham, DH1 3LE, U.K.; Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Caixa Postal 486 31270-901, Belo Horizonte, Minas Gerais, Brazil., Filipe LNS; Department of Biosciences, University of Durham, South Road, Durham, DH1 3LE, U.K., Van Bocxlaer K; York Biomedical Research Institute, Hull York Medical School, University of York, York YO10 5NG, U.K., Price HP; School of Life Sciences, Keele University, Staffordshire, ST5 5BG, U.K., Ibarra-Meneses AV; Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, Quebec J2S 2M2, Canada., Beaudry F; Département de Biomédecine, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, Quebec J2S 2M2, Canada., Fernandez-Prada C; Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, Quebec J2S 2M2, Canada., Whitfield PD; School of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, U.K., Barrett MP; School of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, U.K., Denny PW; Department of Biosciences, University of Durham, South Road, Durham, DH1 3LE, U.K.

المصدر: ACS infectious diseases [ACS Infect Dis] 2024 Aug 09; Vol. 10 (8), pp. 2913-2928. Date of Electronic Publication: 2024 Jul 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Antiprotozoal Agents*/pharmacology , Antiprotozoal Agents*/chemistry, Sphingolipids/metabolism ; Hexosyltransferases/genetics ; Hexosyltransferases/metabolism ; Hexosyltransferases/antagonists & inhibitors ; Leishmania/drug effects ; Leishmania/genetics ; Leishmania/enzymology ; Animals ; Leishmania mexicana/drug effects ; Leishmania mexicana/genetics ; Leishmania mexicana/enzymology ; Glycosphingolipids/metabolism ; Transferases (Other Substituted Phosphate Groups)/genetics ; Transferases (Other Substituted Phosphate Groups)/metabolism

المؤلفون: Negrão NW; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA.; Department of Cellular Biology, University of Georgia, Athens, GA 30602, USA., Crowe LP; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA., Mantilla BS; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA.; Department of Biosciences, Durham University, Durham DHI 3LE, UK., Baptista RP; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA., King-Keller S; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA.; School of Science of Technology (Biology), Georgia Gwinnett College, Lawrenceville, GA 30043, USA., Huang G; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA., Docampo R; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA.; Department of Cellular Biology, University of Georgia, Athens, GA 30602, USA.

المصدر: Pathogens (Basel, Switzerland) [Pathogens] 2023 Feb 28; Vol. 12 (3). Date of Electronic Publication: 2023 Feb 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101596317 Publication Model: Electronic Cited Medium: Print ISSN: 2076-0817 (Print) Linking ISSN: 20760817 NLM ISO Abbreviation: Pathogens Subsets: PubMed not MEDLINE

المؤلفون: Kalesh K; Department of Chemistry, Durham Universitygrid.8250.f, Durham, United Kingdom., Wei W; Department of Biosciences, Durham Universitygrid.8250.f, Durham, United Kingdom., Mantilla BS; Department of Biosciences, Durham Universitygrid.8250.f, Durham, United Kingdom., Roumeliotis TI; Functional Proteomics Group, The Institute of Cancer Research, London, United Kingdom., Choudhary J; Functional Proteomics Group, The Institute of Cancer Research, London, United Kingdom., Denny PW; Department of Biosciences, Durham Universitygrid.8250.f, Durham, United Kingdom.

المصدر: Microbiology spectrum [Microbiol Spectr] 2022 Feb 23; Vol. 10 (1), pp. e0242221. Date of Electronic Publication: 2022 Feb 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: ASM Press Country of Publication: United States NLM ID: 101634614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2165-0497 (Electronic) Linking ISSN: 21650497 NLM ISO Abbreviation: Microbiol Spectr Subsets: MEDLINE

مواضيع طبية MeSH: Transcriptome*, Leishmania mexicana/*genetics , Protozoan Proteins/*genetics , RNA, Protozoan/*genetics , RNA, Untranslated/*genetics , RNA-Binding Proteins/*genetics, Leishmania mexicana/metabolism ; Mass Spectrometry ; Open Reading Frames ; Protein Binding ; Proteomics ; Protozoan Proteins/metabolism ; RNA, Protozoan/metabolism ; RNA, Untranslated/metabolism ; RNA-Binding Proteins/metabolism ; Ribosomal Proteins/genetics ; Ribosomal Proteins/metabolism

المؤلفون: Mantilla BS; Center for Tropical and Emerging Global Diseases, University of Georgiagrid.213876.9, Athens, Georgia, USA.; Department of Biosciences, Durham Universitygrid.8250.f, Durham, United Kingdom., Azevedo C; Medical Research Council Laboratory for Molecular Cell Biology, University College of London, London, United Kingdom.; InnovPlantProject Collaborative Laboratory, Department of New Biopesticides, Elvas, Portugal., Denny PW; Department of Biosciences, Durham Universitygrid.8250.f, Durham, United Kingdom., Saiardi A; Medical Research Council Laboratory for Molecular Cell Biology, University College of London, London, United Kingdom., Docampo R; Center for Tropical and Emerging Global Diseases, University of Georgiagrid.213876.9, Athens, Georgia, USA.; Department of Cellular Biology, University of Georgiagrid.213876.9, Athens, Georgia, USA.

المصدر: MBio [mBio] 2021 Dec 21; Vol. 12 (6), pp. e0198121. Date of Electronic Publication: 2021 Nov 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE

مواضيع طبية MeSH: Histidine Ammonia-Lyase/*metabolism , Organelles/*metabolism , Protozoan Proteins/*metabolism , Trypanosoma cruzi/*enzymology, Alkalies/metabolism ; Amino Acid Motifs ; Calcium/metabolism ; Chagas Disease/parasitology ; Histidine/metabolism ; Histidine Ammonia-Lyase/chemistry ; Histidine Ammonia-Lyase/genetics ; Humans ; Organelles/chemistry ; Polyphosphates/metabolism ; Protozoan Proteins/chemistry ; Protozoan Proteins/genetics ; Trypanosoma cruzi/genetics ; Trypanosoma cruzi/growth & development ; Trypanosoma cruzi/metabolism

المؤلفون: Mantilla BS; Laboratory of Biochemistry of Tryps- LabTryps, Department of Parasitology, Institute of Biomedical Sciences, Universidade de São Paulo, São Paulo, SP, Brazil., Paes-Vieira L; Laboratory of Biochemistry of Tryps- LabTryps, Department of Parasitology, Institute of Biomedical Sciences, Universidade de São Paulo, São Paulo, SP, Brazil.; Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil., de Almeida Dias F; Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Calderano SG; Laboratório de Ciclo Celular, Center of Toxines, Immune response and Cell Signallig, Instituto Butantan, São Paulo, Brasil., Elias MC; Laboratório de Ciclo Celular, Center of Toxines, Immune response and Cell Signallig, Instituto Butantan, São Paulo, Brasil., Cosentino-Gomes D; Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Oliveira PL; Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Meyer-Fernandes JR; Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Silber AM; Laboratory of Biochemistry of Tryps- LabTryps, Department of Parasitology, Institute of Biomedical Sciences, Universidade de São Paulo, São Paulo, SP, Brazil.

المصدر: The Biochemical journal [Biochem J] 2021 Nov 12; Vol. 478 (21), pp. 3891-3903.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

مواضيع طبية MeSH: Chagas Disease/*parasitology , Mitochondria/*metabolism , Proline Oxidase/*metabolism , Rhodnius/*parasitology , Trypanosoma cruzi/*pathogenicity, Animals ; Cell Differentiation

المؤلفون: Mantilla BS; Center for Tropical and Emerging Global Diseases and Department of Cellular Biology, University of Georgia, Athens, GA, USA.; Department of Biosciences, Durham University, Durham, UK., Kalesh K; Department of Chemistry, Durham University, Durham, UK., Brown NW Jr; Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin, Germany.; Department of Chemistry, University of Minnesota-Twin Cities, Minneapolis, MN, USA., Fiedler D; Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin, Germany.; Institut für Chemie, Humboldt Universität zu Berlin, Berlin, Germany., Docampo R; Center for Tropical and Emerging Global Diseases and Department of Cellular Biology, University of Georgia, Athens, GA, USA.

المصدر: Molecular microbiology [Mol Microbiol] 2021 May; Vol. 115 (5), pp. 986-1004. Date of Electronic Publication: 2021 Jan 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 8712028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2958 (Electronic) Linking ISSN: 0950382X NLM ISO Abbreviation: Mol Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: Inositol Phosphates/*metabolism , Phosphotransferases (Phosphate Group Acceptor)/*metabolism , Protozoan Proteins/*metabolism , Trypanosoma cruzi/*growth & development , Trypanosoma cruzi/*metabolism, Magnesium/metabolism ; Mass Spectrometry ; Phosphorylation ; Phosphotransferases (Phosphate Group Acceptor)/genetics ; Proteomics ; Protozoan Proteins/genetics ; Trypanosoma cruzi/enzymology ; Trypanosoma cruzi/genetics

المؤلفون: Mantilla BS; Center for Tropical and Emerging Global Diseases and Department of Cellular Biology, University of Georgia, Athens, Georgia 30602, United States., Amaral LDD; Center for Tropical and Emerging Global Diseases and Department of Cellular Biology, University of Georgia, Athens, Georgia 30602, United States., Jessen HJ; Institute of Organic Chemistry, Faculty of Chemistry and Pharmacy, University of Freiburg, 79104 Freiburg, Germany., Docampo R; Center for Tropical and Emerging Global Diseases and Department of Cellular Biology, University of Georgia, Athens, Georgia 30602, United States.

المصدر: ACS chemical biology [ACS Chem Biol] 2021 Feb 19; Vol. 16 (2), pp. 283-292. Date of Electronic Publication: 2021 Jan 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Inositol Phosphates/*biosynthesis , Trypanosoma cruzi/*metabolism, Gene Knockout Techniques ; Genes, Helminth ; Phosphotransferases (Alcohol Group Acceptor)/genetics ; Phosphotransferases (Alcohol Group Acceptor)/metabolism ; Virulence/genetics

المؤلفون: Marchese L; Laboratory of Biochemistry of Tryps - LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo - USP, 05508-000 São Paulo, Brazil., Olavarria K; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo - USP, 05508-000 São Paulo, Brazil., Mantilla BS; Laboratory of Biochemistry of Tryps - LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo - USP, 05508-000 São Paulo, Brazil., Avila CC; Center of Toxins, Immune Response and Cell Signaling, Butantan Institute, 05503-900 São Paulo, SP, Brazil., Souza ROO; Laboratory of Biochemistry of Tryps - LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo - USP, 05508-000 São Paulo, Brazil., Damasceno FS; Laboratory of Biochemistry of Tryps - LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo - USP, 05508-000 São Paulo, Brazil., Elias MC; Center of Toxins, Immune Response and Cell Signaling, Butantan Institute, 05503-900 São Paulo, SP, Brazil., Silber AM; Laboratory of Biochemistry of Tryps - LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo - USP, 05508-000 São Paulo, Brazil.

المصدر: The Biochemical journal [Biochem J] 2020 May 29; Vol. 477 (10), pp. 1827-1845.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

مواضيع طبية MeSH: NADP/*metabolism , Proline/*metabolism , Pyrroles/*metabolism , Trypanosoma cruzi/*metabolism, Cytosol/metabolism ; Electron Transport ; Glutamic Acid/metabolism ; Mitochondria/metabolism ; Oxidation-Reduction ; Pyrroline Carboxylate Reductases/metabolism

المؤلفون: Barisón MJ; From the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil., Rapado LN; From the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil., Merino EF; the Department of Biochemistry and Virginia Tech Center for Drug Discovery, Virginia Tech, Blacksburg, Virginia 24061, and., Furusho Pral EM; From the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil., Mantilla BS; From the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil., Marchese L; From the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil., Nowicki C; the Facultad de Farmacia y Bioquímica, Instituto de Química y Fisicoquímica Biológica (IQUIFIB-CONICET), Universidad de Buenos Aires, 1113 Buenos Aires, Argentina., Silber AM; From the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil, asilber@usp.br., Cassera MB; the Department of Biochemistry and Virginia Tech Center for Drug Discovery, Virginia Tech, Blacksburg, Virginia 24061, and maria.cassera@uga.edu.

المصدر: The Journal of biological chemistry [J Biol Chem] 2017 May 26; Vol. 292 (21), pp. 8964-8977. Date of Electronic Publication: 2017 Mar 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Metabolome/*physiology , Trypanosoma cruzi/*growth & development, Life Cycle Stages/physiology ; Metabolomics

المؤلفون: Mantilla BS; Laboratory of Biochemistry of Tryps - LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Marchese L; Laboratory of Biochemistry of Tryps - LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Casas-Sánchez A; Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom., Dyer NA; Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom., Ejeh N; Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom., Biran M; Centre de Résonance Magnétique des Systemes Biologiques, Université Bordeaux, Bordeaux, France., Bringaud F; Centre de Résonance Magnétique des Systemes Biologiques, Université Bordeaux, Bordeaux, France., Lehane MJ; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom., Acosta-Serrano A; Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom., Silber AM; Laboratory of Biochemistry of Tryps - LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.

المصدر: PLoS pathogens [PLoS Pathog] 2017 Jan 23; Vol. 13 (1), pp. e1006158. Date of Electronic Publication: 2017 Jan 23 (Print Publication: 2017).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

مواضيع طبية MeSH: Host-Parasite Interactions/*physiology , Insect Vectors/*parasitology , Proline/*metabolism , Trypanosoma brucei brucei/*metabolism , Trypanosomiasis/*metabolism , Tsetse Flies/*parasitology, Adaptation, Physiological/physiology ; Animals ; Blotting, Western ; Cell Separation ; Flow Cytometry ; Gene Knockdown Techniques ; Magnetic Resonance Spectroscopy ; Microscopy, Fluorescence