نتائج البحث - "Manuel A. Sepulveda"

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دورية أكاديمية

Anti-tumor activity of a T-helper 1 multiantigen vaccine in a murine model of prostate cancer

المؤلفون: Denise L. Cecil, Benjamin Curtis, Ekram Gad, Michael Gormley, Andrew E. Timms, Lauren Corulli, Rinke Bos, Rajendra N. Damle, Manuel A. Sepulveda, Mary L. Disis

المصدر: Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/747694e3df3f4e66a2c860aa790fac69

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Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine

المؤلفون: Mathieu Gigoux, Morten O. Holmström, Roberta Zappasodi, Joseph J. Park, Stephane Pourpe, Cansu Cimen Bozkus, Levi M. B. Mangarin, David Redmond, Svena Verma, Sara Schad, Mariam M. George, Divya Venkatesh, Arnab Ghosh, David Hoyos, Zaki Molvi, Baransel Kamaz, Anna E. Marneth, William Duke, Matthew J. Leventhal, Max Jan, Vincent T. Ho, Gabriela S. Hobbs, Trine Alma Knudsen, Vibe Skov, Lasse Kjær, Thomas Stauffer Larsen, Dennis Lund Hansen, R. Coleman Lindsley, Hans Hasselbalch, Jacob H. Grauslund, Thomas L. Lisle, Özcan Met, Patrick Wilkinson, Benjamin Greenbaum, Manuel A. Sepulveda, Timothy Chan, Raajit Rampal, Mads H. Andersen, Omar Abdel-Wahab, Nina Bhardwaj, Jedd D. Wolchok, Ann Mullally, Taha Merghoub

المصدر: Science Translational Medicine. 14

مصطلحات موضوعية: Myeloproliferative Disorders, General Medicine, Janus Kinase 2, Cancer Vaccines, Major Histocompatibility Complex, Mice, Inbred C57BL, Mice, Neoplasms, Mutation, Vaccines, Subunit, Animals, Humans, Calreticulin, Peptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5ff55140f482ee33ec173cfebf6e6b
https://doi.org/10.1126/scitranslmed.aba4380

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Analysis of classical neutrophils and polymorphonuclear myeloid-derived suppressor cells in cancer patients and tumor-bearing mice

المصدر: The Journal of Experimental Medicine

مصطلحات موضوعية: 0301 basic medicine, Tumor Immunology, Lung Neoplasms, Lymphoma, Neutrophils, CD14, Immunology, Population, Innate Immunity and Inflammation, chemical and pharmacologic phenomena, Biology, Technical Advances and Resources, Flow cytometry, 03 medical and health sciences, Carcinoma, Lewis Lung, Mice, 0302 clinical medicine, Immune system, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, medicine, Immunology and Allergy, Animals, Humans, RNA-Seq, education, education.field_of_study, medicine.diagnostic_test, Cancer, hemic and immune systems, Gene signature, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Tumor progression, 030220 oncology & carcinogenesis, Case-Control Studies, Cancer research, Myeloid-derived Suppressor Cell, Female, Single-Cell Analysis, Transcriptome

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3dd2b8f1a8855e4b956149a7520a0c
http://europepmc.org/articles/PMC7879582

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VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer

المؤلفون: Christopher J. Logothetis, Curtis A. Pettaway, Jianjun Gao, Jianfeng Chen, Lewis Zhichang Shi, Eleni Efstathiou, Patricia Troncoso, Jennifer A. Wargo, Hong Chen, Jingjing Sun, John F. Ward, Manuel A. Sepulveda, Ignacio I. Wistuba, Luis M Vence, Hao Zhao, Padmanee Sharma, Jorge Blando, James P. Allison, Sumit K. Subudhi

المصدر: Nature Medicine. 23:551-555

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, B7 Antigens, T-Lymphocytes, medicine.medical_treatment, Fluorescent Antibody Technique, B7-H1 Antigen, Mice, Prostate cancer, 0302 clinical medicine, Neoadjuvant therapy, Prostatectomy, Antibodies, Monoclonal, General Medicine, Middle Aged, Flow Cytometry, Immunohistochemistry, Neoadjuvant Therapy, 030220 oncology & carcinogenesis, Nivolumab, medicine.drug, Adult, medicine.medical_specialty, Antineoplastic Agents, Ipilimumab, Adenocarcinoma, In Vitro Techniques, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Cell Line, Tumor, Internal medicine, medicine, Animals, Humans, Aged, business.industry, Macrophages, Membrane Proteins, Prostatic Neoplasms, Immunotherapy, medicine.disease, Immune checkpoint, Clinical trial, Disease Models, Animal, 030104 developmental biology, Tissue Array Analysis, Immunology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba10adf21d49fef7b418d37f3ee57f8
https://doi.org/10.1038/nm.4308

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5

Impact of Cell-surface Antigen Expression on Target Engagement and Function of an Epidermal Growth Factor Receptor × c-MET Bispecific Antibody

المؤلفون: Sheri Moores, Eilyn R. Lacy, Jose Pardinas, Manuel A. Sepulveda, Ken Boakye, Mark L. Chiu, Barbara Bushey, Renouard Sanders, Stephen Jarantow

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: hepatocyte growth factor/scatter factor (HGF/SF), Models, Molecular, C-Met, Biology, Biochemistry, epidermal growth factor (EGF), Immunoglobulin Fab Fragments, chemistry.chemical_compound, quantitative flow cytometry, Growth factor receptor, Cell surface receptor, Cell Line, Tumor, Antibodies, Bispecific, Humans, ERBB3, Avidity, Molecular Targeted Therapy, RNA, Messenger, Epidermal growth factor receptor, Phosphorylation, Protein Structure, Quaternary, Receptor, Molecular Biology, c-MET, Molecular Bases of Disease, Cell Biology, Proto-Oncogene Proteins c-met, epidermal growth factor receptor (EGFR), ErbB Receptors, bispecific antibody, Gene Expression Regulation, chemistry, Hepatocyte Growth Factor Receptor, Antigens, Surface, Mutation, Cancer research, biology.protein, cancer therapy, Protein Multimerization, cell-surface receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a0783529e37128297c7e245bbb9ec90
https://doi.org/10.1074/jbc.m115.651653

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Inflammatory markers to predict prognosis in renal cell carcinoma (RCC) patients treated with immune checkpoint inhibitors (ICIs)

المؤلفون: Alfonso Gomez De Liano Lista, Javier Pozas, Juan Manuel Manuel Sepulveda Sanchez, Teresa Alonso Gordoa, Maria Cruz Martin Soberón, Guillermo Velasco, Alberto Carretero-González, Lucia Carril, Jesús M. Paramio, Alejandra Bernardini, Daniel Castellano

المصدر: Web of Science

مصطلحات موضوعية: Cancer Research, Risk groups, Oncology, Renal cell carcinoma, business.industry, Immune checkpoint inhibitors, medicine, Cancer research, medicine.disease, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257b89f2fc3a25e7bed8eac2390f94dc
https://doi.org/10.1200/jco.2020.38.6_suppl.757

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Engagement of the ICOS pathway markedly enhances efficacy of CTLA-4 blockade in cancer immunotherapy

المؤلفون: Xiaozhou Fan, Sergio A. Quezada, Padmanee Sharma, James P. Allison, Manuel A. Sepulveda

المصدر: The Journal of Experimental Medicine

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, medicine.medical_treatment, Immunology, Melanoma, Experimental, chemical and pharmacologic phenomena, Ipilimumab, CD8-Positive T-Lymphocytes, Ligands, Cancer Vaccines, Article, Inducible T-Cell Co-Stimulator Protein, Mice, Lymphocytes, Tumor-Infiltrating, Cancer immunotherapy, medicine, Animals, Immunology and Allergy, Cytotoxic T cell, CTLA-4 Antigen, Immunosuppression Therapy, Antigen Presentation, business.industry, Antibodies, Monoclonal, Prostatic Neoplasms, Cancer, Immunotherapy, medicine.disease, Up-Regulation, 3. Good health, Blockade, ICOS LIGAND, Disease Models, Animal, CTLA-4, Cytokines, business, Immunologic Memory, Signal Transduction, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8131bbbed97f1c5bc6ac4a39df3f2d4
https://doi.org/10.1084/jem.20130590

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Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients

المصدر: Science Immunology. 1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b99c66c9e026f006426b2977d25f89
https://doi.org/10.1126/sciimmunol.aaf8943

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Phase I study of CC-90010 in patients with advanced solid tumors and relapsed/refractory non-Hodgkin lymphoma (R/R NHL)

المؤلفون: Tatiana Hernandez-Guerrero, Juan De Alvaro, Manisha Lamba, Ellen Filvaroff, Olga Ferrero, Marina Arias, Juan Manuel Manuel Sepulveda Sanchez, Marlene Zuraek, Zariana Nikolova, Victor Moreno, Tania Sánchez Pérez, Irene Brana, Rafael Sarmiento, Bernard Doger, Bishoy Hanna, O. Saavedra, Ida Aronchik, Maria Vieito Villar, Jorge DiMartino

المصدر: Journal of Clinical Oncology. 37:3015-3015

مصطلحات موضوعية: Cancer Research, business.industry, medicine.disease_cause, Phase i study, Bromodomain, Oncology, Relapsed refractory, medicine, Cancer research, Hodgkin lymphoma, In patient, Epigenetics, Carcinogenesis, business, Gene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::aa718a45aa431f92c5b76a3020c1389e
https://doi.org/10.1200/jco.2019.37.15_suppl.3015

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Combination of statin/vitamin D and metastatic castration-resistant prostate cancer (mCRPC): A post-hoc analysis of two randomized clinical trials

المؤلفون: Alberto Carretero-González, Guillermo Velasco, David Lorente, Daniel Castellano, Juan Manuel Manuel Sepulveda Sanchez, Maria Cruz Martin Soberón, David Lora

المصدر: Journal of Clinical Oncology. 37:6617-6617

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Statin, medicine.drug_class, business.industry, Castration resistant, medicine.disease, law.invention, Retrospective database, Prostate cancer, Randomized controlled trial, law, Internal medicine, Post-hoc analysis, medicine, Vitamin D and neurology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5a3449e34068e97114b43a07214f252e
https://doi.org/10.1200/jco.2019.37.15_suppl.6617

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