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المؤلفون: Rinat Zaynagetdinov, Kai Schiemann, Kalyan Nallaparaju, Natalya Belousova, Armine Matevossian, Zhouxiang Chen, Giorgio Kradjian, Meghana Pandya, Nemisha Dawra, Eva-Maria Krauel, Elissaveta Petrova, Oliver Poeschke, David Fischer, Marc Lecomte, Andree Blaukat, Bayard Huck, Jacques Moisan
المصدر: Cancer Research. 82:3499-3499
مصطلحات موضوعية: Cancer Research, Oncology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4d0f249470dc089a58550abfb940baab
https://doi.org/10.1158/1538-7445.am2022-3499 -
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المؤلفون: Christian Jede, Lassina Badolo, Christian Wagner, Christian Weber, Markus Weigandt, Mirko Koziolek, Holger Kubas, Werner Weitschies, Marc Lecomte
المصدر: Molecular Pharmaceutics. 16:3938-3947
مصطلحات موضوعية: Drug, Indazoles, media_common.quotation_subject, Bicarbonate, Administration, Oral, Pharmaceutical Science, 02 engineering and technology, Buffers, Methylcellulose, Models, Biological, 030226 pharmacology & pharmacy, Phosphates, 03 medical and health sciences, chemistry.chemical_compound, Drug Delivery Systems, 0302 clinical medicine, Pharmacokinetics, In vivo, Drug Discovery, medicine, Animals, Chemical Precipitation, Rats, Wistar, Dissolution, media_common, Sulfonamides, Supersaturation, Chromatography, Chemistry, Precipitation (chemistry), Lapatinib, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, Rats, Gastrointestinal Tract, Bicarbonates, Drug Liberation, Ketoconazole, Pyrimidines, Solubility, Gastrointestinal Absorption, Molecular Medicine, Female, 0210 nano-technology, medicine.drug
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المؤلفون: Karsten Mäder, Lassina Badolo, Christina Fink, Sheila-Annie Peters, Marc Lecomte, Knut Wagner
المصدر: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 152
مصطلحات موضوعية: Human food, Physiologically based pharmacokinetic modelling, Chemistry, Drug discovery, Pharmaceutical Science, Administration, Oral, 02 engineering and technology, Absorption (skin), Pharmacology, 021001 nanoscience & nanotechnology, 030226 pharmacology & pharmacy, Systemic circulation, Models, Biological, Rats, 03 medical and health sciences, 0302 clinical medicine, Drug development, Pharmacokinetics, Drug Development, Solubility, Animals, Humans, 0210 nano-technology
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المصدر: Xenobiotica; the fate of foreign compounds in biological systems. 50(3)
مصطلحات موضوعية: Pharmacology, Volume of distribution, Physiologically based pharmacokinetic modelling, Drug discovery, Health, Toxicology and Mutagenesis, Extrapolation, General Medicine, Toxicology, computer.software_genre, 030226 pharmacology & pharmacy, Biochemistry, Data set, 03 medical and health sciences, 0302 clinical medicine, Pharmaceutical Preparations, 030220 oncology & carcinogenesis, Drug Discovery, Humans, Tissue Distribution, Allometry, Data mining, computer, Mathematics
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المؤلفون: Fabien Schmidlin, Sophie Bozec, Franck F. Lepifre, Denis Carniato, Serge Christmann-Franck, Eric Valeur, Caroline Leriche, Didier Roche, Marc Lecomte, Liliane Doare, Christine Charon
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:3682-3685
مصطلحات موضوعية: Drug, Molecular model, medicine.drug_class, Stereochemistry, media_common.quotation_subject, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Biochemistry, Chemical synthesis, Structure-Activity Relationship, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Drug Discovery, medicine, Humans, Computer Simulation, Spiro Compounds, Enzyme Inhibitors, Binding site, Molecular Biology, IC50, media_common, chemistry.chemical_classification, Binding Sites, Organic Chemistry, Amides, Enzyme, chemistry, Drug Design, Molecular Medicine, Selectivity
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المؤلفون: Eric Valeur, Marc Lecomte, Christine Charon, Caroline Leriche, Franck F. Lepifre, Liliane Doare, Fabien Schmidlin, Denis Carniato, Serge Christmann-Franck, Didier Roche, Ulrich Graedler, Sophie Bozec
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:2674-2678
مصطلحات موضوعية: Stereochemistry, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Drug design, Carboxamide, Dehydrogenase, Biochemistry, Chemical synthesis, Mice, Structure-Activity Relationship, chemistry.chemical_compound, 11-beta-Hydroxysteroid Dehydrogenase Type 2, 3T3-L1 Cells, Amide, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Drug Discovery, medicine, Animals, Humans, Enzyme Inhibitors, Molecular Biology, IC50, chemistry.chemical_classification, Organic Chemistry, Amides, Rats, Enzyme, chemistry, Molecular Medicine, Lead compound, hormones, hormone substitutes, and hormone antagonists
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المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1689:202-211
مصطلحات موضوعية: Glycation End Products, Advanced, Ceramide, Apoptosis, Retina, Amino Acid Chloromethyl Ketones, Caspase-10, chemistry.chemical_compound, Diabetic retinopathy, Annexin, Glycation, medicine, Animals, Caspase 10, Molecular Biology, Caspase, Pericyte, Diacylglycerol kinase, Advanced glycation end-product, Caspase 8, biology, Cell biology, medicine.anatomical_structure, chemistry, Biochemistry, Caspases, biology.protein, Molecular Medicine, Cattle, Oligopeptides
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المؤلفون: Isabelle Delton-Vandenbroucke, Martine Carreras, Michel Lagarde, Marc Lecomte, Evelyne Véricel, Caroline Januel
المصدر: Free Radical Biology and Medicine. 30:895-904
مصطلحات موضوعية: medicine.medical_specialty, Antioxidant, Docosahexaenoic Acids, Endothelium, medicine.medical_treatment, Blotting, Western, Plasmalogens, medicine.disease_cause, Biochemistry, Gene Expression Regulation, Enzymologic, Retina, Cell Line, chemistry.chemical_compound, Malondialdehyde, Physiology (medical), Internal medicine, medicine, Animals, Vitamin E, Aorta, chemistry.chemical_classification, Glutathione Peroxidase, Dose-Response Relationship, Drug, Chemistry, Phosphatidylethanolamines, Glutathione peroxidase, Fatty Acids, food and beverages, Glutathione, Oxidative Stress, Endocrinology, medicine.anatomical_structure, Docosahexaenoic acid, Phosphatidylcholines, Cattle, lipids (amino acids, peptides, and proteins), Endothelium, Vascular, Oxidative stress
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المصدر: Biochemical and Biophysical Research Communications. 281:78-83
مصطلحات موضوعية: Glycation End Products, Advanced, medicine.medical_specialty, Cell, Biophysics, Apoptosis, Models, Biological, digestive system, Biochemistry, Glycosphingolipids, chemistry.chemical_compound, Glycation, Gangliosides, Internal medicine, medicine, Animals, Molecular Biology, Cells, Cultured, Chromatography, High Pressure Liquid, chemistry.chemical_classification, Diabetic Retinopathy, Ganglioside, Microcirculation, Fatty Acids, Fatty acid, Retinal, Cell Biology, Diabetic retinopathy, Glycosphingolipid, medicine.disease, carbohydrates (lipids), medicine.anatomical_structure, Endocrinology, chemistry, Metabolic effects, Cattle, lipids (amino acids, peptides, and proteins), Endothelium, Vascular, Cell Division
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المصدر: Life Sciences. 64:1571-1583
مصطلحات موضوعية: Glycation End Products, Advanced, Male, Glycosylation, Fucosyltransferase, Glycoside Hydrolases, Sialyltransferase, Retina, Streptozocin, General Biochemistry, Genetics and Molecular Biology, Fucose, Diabetes Mellitus, Experimental, chemistry.chemical_compound, Glycation, Animals, Fucosidase, Rats, Wistar, General Pharmacology, Toxicology and Pharmaceutics, Cells, Cultured, Galactosyltransferase, biology, Glycosyltransferases, General Medicine, Rats, Sialic acid, Biochemistry, chemistry, biology.protein, Cattle