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المؤلفون: Marciano DC; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA. david.marciano@bcm.edu., Wang C; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA., Hsu TK; The Verna and Marrs McLean Department of Biochemistry & Molecular Biology, Baylor College of Medicine, Houston, TX, 77030, USA., Bourquard T; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA., Atri B; Structural and Computational Biology & Molecular Biophysics Program, Baylor College of Medicine, Houston, TX, 77030, USA.; Clara Analytics Inc., 451 El Camino Real #201, Santa Clara, CA, 95050, USA., Nehring RB; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.; The Verna and Marrs McLean Department of Biochemistry & Molecular Biology, Baylor College of Medicine, Houston, TX, 77030, USA.; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA., Abel NS; Department of Pharmacology, Baylor College of Medicine, Houston, TX, 77030, USA., Bowling EA; The Verna and Marrs McLean Department of Biochemistry & Molecular Biology, Baylor College of Medicine, Houston, TX, 77030, USA., Chen TJ; Integrative Molecular & Biomedical Biosciences Program, Baylor College of Medicine, Houston, TX, 77030, USA., Lurie PD; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA., Katsonis P; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA., Rosenberg SM; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.; The Verna and Marrs McLean Department of Biochemistry & Molecular Biology, Baylor College of Medicine, Houston, TX, 77030, USA.; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.; Integrative Molecular & Biomedical Biosciences Program, Baylor College of Medicine, Houston, TX, 77030, USA., Herman C; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA., Lichtarge O; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA. lichtarge@bcm.edu.; Structural and Computational Biology & Molecular Biophysics Program, Baylor College of Medicine, Houston, TX, 77030, USA. lichtarge@bcm.edu.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA. lichtarge@bcm.edu.; Computational and Integrative Biomedical Research Center, Baylor College of Medicine, Houston, TX, 77030, USA. lichtarge@bcm.edu.

المصدر: Nature communications [Nat Commun] 2022 Jun 09; Vol. 13 (1), pp. 3189. Date of Electronic Publication: 2022 Jun 09.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Bacterial Agents*/pharmacology , Drug Resistance, Bacterial*/genetics , Escherichia coli*/drug effects , Escherichia coli*/genetics , Escherichia coli Proteins*/genetics, Ciprofloxacin/pharmacology ; Colistin/pharmacology ; Microbial Sensitivity Tests ; Mutation

المؤلفون: Wang C; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Konecki DM; Quantitative and Computational Biosciences Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA., Marciano DC; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Govindarajan H; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Williams AM; Cancer and Cell Biology Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA., Wastuwidyaningtyas B; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Bourquard T; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Katsonis P; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Lichtarge O; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Quantitative and Computational Biosciences Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA.; Cancer and Cell Biology Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA.; Computational and Integrative Biomedical Research Center, Baylor College of Medicine, Houston, TX 77030, USA.

المصدر: Bioinformatics (Oxford, England) [Bioinformatics] 2021 Nov 18; Vol. 37 (22), pp. 4033-4040.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9808944 Publication Model: Print Cited Medium: Internet ISSN: 1367-4811 (Electronic) Linking ISSN: 13674803 NLM ISO Abbreviation: Bioinformatics Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19* , Viral Vaccines*/genetics, Humans ; SARS-CoV-2/genetics ; Proteome ; COVID-19 Vaccines

SCR Organism: SARS-CoV-2 variants

المؤلفون: Wang C; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Konecki DM; Quantitative and Computational Biosciences Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA., Marciano DC; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Govindarajan H; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Williams AM; Cancer and Cell Biology Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA., Wastuwidyaningtyas B; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Bourquard T; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; MAbSilico, Nouzilly, Centre, France, EU., Katsonis P; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Lichtarge O; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Quantitative and Computational Biosciences Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA.; Cancer and Cell Biology Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA.; Computational and Integrative Biomedical Research Center, Baylor College of Medicine, Houston, TX 77030, USA.

المصدر: Research square [Res Sq] 2021 Feb 15. Date of Electronic Publication: 2021 Feb 15.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE

المؤلفون: Swings T; Centre of Microbial and Plant Genetics, KU Leuven - University of Leuven, Kasteelpark Arenberg 20, 3001, Leuven, Belgium.; Center for Microbiology, VIB, Kasteelpark Arenberg 20, 3001, Leuven, Belgium., Marciano DC; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA., Atri B; Quantitative and Computational Biosciences, Baylor College of Medicine, Houston, TX, 77030, USA., Bosserman RE; Department of Microbiology and Molecular Genetics, McGovern Medical School, Houston, TX, 77030, USA., Wang C; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA., Leysen M; Centre of Microbial and Plant Genetics, KU Leuven - University of Leuven, Kasteelpark Arenberg 20, 3001, Leuven, Belgium., Bonte C; Centre of Microbial and Plant Genetics, KU Leuven - University of Leuven, Kasteelpark Arenberg 20, 3001, Leuven, Belgium., Schalck T; Centre of Microbial and Plant Genetics, KU Leuven - University of Leuven, Kasteelpark Arenberg 20, 3001, Leuven, Belgium.; Center for Microbiology, VIB, Kasteelpark Arenberg 20, 3001, Leuven, Belgium., Furey I; Department of Pharmacology, Baylor College of Medicine, Houston, TX, 77030, USA., Van den Bergh B; Centre of Microbial and Plant Genetics, KU Leuven - University of Leuven, Kasteelpark Arenberg 20, 3001, Leuven, Belgium.; Center for Microbiology, VIB, Kasteelpark Arenberg 20, 3001, Leuven, Belgium., Verstraeten N; Centre of Microbial and Plant Genetics, KU Leuven - University of Leuven, Kasteelpark Arenberg 20, 3001, Leuven, Belgium.; Center for Microbiology, VIB, Kasteelpark Arenberg 20, 3001, Leuven, Belgium., Christie PJ; Department of Microbiology and Molecular Genetics, McGovern Medical School, Houston, TX, 77030, USA., Herman C; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA., Lichtarge O; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA. lichtarge@bcm.edu.; Quantitative and Computational Biosciences, Baylor College of Medicine, Houston, TX, 77030, USA. lichtarge@bcm.edu.; Department of Pharmacology, Baylor College of Medicine, Houston, TX, 77030, USA. lichtarge@bcm.edu.; Computational and Integrative Biomedical Research Center, Baylor College of Medicine, Houston, TX, 77030, USA. lichtarge@bcm.edu., Michiels J; Centre of Microbial and Plant Genetics, KU Leuven - University of Leuven, Kasteelpark Arenberg 20, 3001, Leuven, Belgium. jan.michiels@kuleuven.vib.be.; Center for Microbiology, VIB, Kasteelpark Arenberg 20, 3001, Leuven, Belgium. jan.michiels@kuleuven.vib.be.

المصدر: Nature communications [Nat Commun] 2018 Jun 08; Vol. 9 (1), pp. 2231. Date of Electronic Publication: 2018 Jun 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems*, DNA Nucleotidyltransferases/*metabolism , Gene Editing/*methods , RNA, Guide, CRISPR-Cas Systems/*metabolism, Binding Sites/genetics ; DNA Nucleotidyltransferases/genetics ; DNA, Bacterial/genetics ; DNA, Bacterial/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Gene Knockout Techniques ; Genome, Bacterial/genetics ; Models, Genetic ; Mutation ; RNA, Guide, CRISPR-Cas Systems/genetics

المؤلفون: Marciano DC; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Lua RC; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Herman C; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Lichtarge O; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.; Computational and Integrative Biomedical Research Center, Baylor College of Medicine, Houston, Texas 77030, USA.

المصدر: Physical review letters [Phys Rev Lett] 2016 Jun 24; Vol. 116 (25), pp. 258104. Date of Electronic Publication: 2016 Jun 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Physical Society Country of Publication: United States NLM ID: 0401141 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1079-7114 (Electronic) Linking ISSN: 00319007 NLM ISO Abbreviation: Phys Rev Lett Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation* , Homeostasis* , Mutation* , Transcription, Genetic*, Escherichia coli/*genetics, Gene Regulatory Networks ; Promoter Regions, Genetic ; Transcription Factors

المؤلفون: Mullany LK; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Wong KK; Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston TX 77030, USA., Marciano DC; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Katsonis P; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., King-Crane ER; Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston TX 77030, USA., Ren YA; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Lichtarge O; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Richards JS; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. Electronic address: joanner@bcm.edu.

المصدر: Neoplasia (New York, N.Y.) [Neoplasia] 2015 Oct; Vol. 17 (10), pp. 789-803.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 100886622 Publication Model: Print Cited Medium: Internet ISSN: 1476-5586 (Electronic) Linking ISSN: 14765586 NLM ISO Abbreviation: Neoplasia Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis* , DNA Copy Number Variations*, Imidazoles/*metabolism , Mutation/*genetics , Ovarian Neoplasms/*genetics , Ovarian Neoplasms/*pathology , Piperazines/*metabolism , Tumor Suppressor Protein p53/*genetics, Animals ; Cell Survival ; Female ; Humans ; Mice ; Ovarian Neoplasms/metabolism ; RNA, Small Interfering/genetics ; Tumor Cells, Cultured ; Tumor Suppressor Protein p53/antagonists & inhibitors

المؤلفون: Lua RC; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Marciano DC; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Katsonis P; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Adikesavan AK; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Wilkins AD; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Computational and Integrative Biomedical Research Center, Baylor College of Medicine, Houston, TX 77030, USA., Lichtarge O; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Computational and Integrative Biomedical Research Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: lichtarge@bcm.edu.

المصدر: Progress in biophysics and molecular biology [Prog Biophys Mol Biol] 2014 Nov-Dec; Vol. 116 (2-3), pp. 194-202. Date of Electronic Publication: 2014 May 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Review

بيانات الدورية: Publisher: Pergamon Press Country of Publication: England NLM ID: 0401233 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1732 (Electronic) Linking ISSN: 00796107 NLM ISO Abbreviation: Prog Biophys Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Computational Biology/*methods , Protein Interaction Mapping/*methods , Proteins/*metabolism, Humans ; Proteins/chemistry ; Substrate Specificity

المؤلفون: Marciano DC; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: david.marciano@bcm.edu., Lua RC; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Katsonis P; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Amin SR; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Biology Department, University of St. Thomas, Houston, TX 77006, USA., Herman C; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Lichtarge O; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Computational and Integrative Biomedical Research Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: lichtarge@bcm.edu.

المصدر: Cell reports [Cell Rep] 2014 Jun 26; Vol. 7 (6), pp. 1789-95. Date of Electronic Publication: 2014 Jun 05.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Amino Acid Substitution* , Biological Evolution* , Gene Expression Regulation*, Bacterial Proteins/genetics ; Feedback ; Models, Genetic ; Selection, Genetic ; Serine Endopeptidases/genetics

المؤلفون: Wilkins AD; Department of Molecular and Human Genetics, CIBR Center for Computational and Integrative Biomedical Research and Program in Structural and Computational Biology & Molecular Biophysics, Baylor College of Medicine, Houston, TX 77030 and Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Venner E, Marciano DC, Erdin S, Atri B, Lua RC, Lichtarge O

المصدر: Bioinformatics (Oxford, England) [Bioinformatics] 2013 Nov 01; Vol. 29 (21), pp. 2714-21. Date of Electronic Publication: 2013 Sep 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9808944 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1367-4811 (Electronic) Linking ISSN: 13674803 NLM ISO Abbreviation: Bioinformatics Subsets: MEDLINE

مواضيع طبية MeSH: Protein Conformation*, Sequence Analysis, Protein/*methods, Algorithms ; Bacterial Proteins/chemistry ; Epistasis, Genetic ; Evolution, Molecular ; Molecular Sequence Annotation ; Mutation ; Proteins/chemistry ; Proteins/genetics ; Proteome/chemistry ; Serine Endopeptidases/chemistry