المؤلفون: Marco A. S. Baptista, Kuldip D. Dave, Niketa P. Sheth, Shehan N. De Silva, Kirsten M. Carlson, Yasmin N. Aziz, Brian K. Fiske, Todd B. Sherer, Mark A. Frasier

المصدر: Disease Models & Mechanisms, Vol 6, Iss 6, Pp 1316-1324 (2013)

مصطلحات موضوعية: Medicine, Pathology, RB1-214

وصف الملف: electronic resource

Relation: http://dmm.biologists.org/content/6/6/1316; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

URL الوصول: https://doaj.org/article/303759b3808c4f2a93495588bcc24a37

المؤلفون: Gary Rafaloff, Richard K. Wyse, Kevin McFarthing, Simon R.W. Stott, Marco A. S. Baptista

المصدر: Journal of Parkinson's Disease

مصطلحات موضوعية: 0301 basic medicine, Drug, medicine.medical_specialty, Parkinson's disease, Coronavirus disease 2019 (COVID-19), media_common.quotation_subject, Disease, World health, Antiparkinson Agents, Clinical Trials Review, 03 medical and health sciences, Cellular and Molecular Neuroscience, Clinical trials, 0302 clinical medicine, Drug Development, Pandemic, medicine, Humans, Intensive care medicine, Parkinson’s, media_common, Clinical Trials as Topic, disease modification, COVID-19, Parkinson Disease, medicine.disease, gene therapy, studies, Clinical trial, 030104 developmental biology, Drug development, inflammation, neuroprotection, immunotherapy, Neurology (clinical), 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8aff13ce1faec137a9e07dcbb637e6
https://doi.org/10.3233/jpd-219006

المؤلفون: Marco A. S. Baptista, Katerina Melachroinou, Sushma Narayan, Leonidas Stefanis, Katie Kopil, Najah Levers, Roy N. Alcalay, Neal Joshi, Shalini Padmanabhan, Christopher Liong, Samantha J. Hutten, Min Suk Kang, Un Jung Kang, Hardy J. Rideout

المصدر: Movement Disorders. 35:2095-2100

مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, business.industry, Kinase, Endogeny, Leucine-rich repeat, Peripheral blood mononuclear cell, LRRK2, In vitro, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Enzyme, Neurology, chemistry, Cancer research, Medicine, Neurology (clinical), Kinase activity, business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::186288798a19a717939801eb067b37a1
https://doi.org/10.1002/mds.28175

المؤلفون: Carlos Cabrera, Samantha J. Hutten, Rosemary Lawrence-Henderson, Neal Joshi, Christopher Liong, Sushma Narayan, Marco A. S. Baptista, Alison Joyce, Kalpana Merchant, Roy N. Alcalay, Thong C. Ma, Michele Wolfe, Shalini Padmanabhan, Najah Levers, Donal Gorman, Thomas A. Lanz

المصدر: Journal of Parkinson's Disease

مصطلحات موضوعية: Research Report, Adult, Male, 0301 basic medicine, Parkinson's disease, Disease, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Peripheral blood mononuclear cell, Cohort Studies, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Humans, Medicine, Phosphorylation, Aged, Aged, 80 and over, Kinase, business.industry, Parkinson Disease, Middle Aged, medicine.disease, LRRK2, nervous system diseases, pharmacodynamic, 030104 developmental biology, Pharmacodynamics, Immunology, Parkinson’s disease, Leukocytes, Mononuclear, biomarker, Biomarker (medicine), Female, Neurology (clinical), blood cells, business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac5d8df93e3b47e08ddb4442453e7f1c
https://doi.org/10.3233/jpd-191786

المؤلفون: Kalpana M. Merchant, Caitlin M. Kehoe, Shalini Padmanabhan, Amelia K. Boehme, Sushma Narayan, Marco A. S. Baptista, Roy N. Alcalay, Elizabeth Tengstrand, Frank Hsieh

المصدر: Movement Disorders

مصطلحات موضوعية: Male, 0301 basic medicine, Heterozygote, medicine.medical_specialty, Urinary system, Urine, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, medicine.disease_cause, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Parkinsonian Disorders, Internal medicine, medicine, Humans, Cognitive decline, Research Articles, Aged, Mutation, Kinase, Parkinson Disease, Middle Aged, Phosphate, LRRK2, nervous system diseases, Monoacylglycerol lipase, Phenotype, 030104 developmental biology, Endocrinology, Neurology, chemistry, Female, Neurology (clinical), Biomarkers, 030217 neurology & neurosurgery, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89635711318f51048ffaf879d51398a3
https://doi.org/10.1002/mds.27818

المؤلفون: Marco A. S. Baptista, S. Pablo Sardi

مصطلحات موضوعية: Parkinson's disease, Disease modification, Underlying disease, business.industry, medicine, Disease, medicine.disease, business, LRRK2, Neuroscience, Unmet needs

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0ed75ba9e51f5a2916015c8addae9956
https://doi.org/10.1016/b978-0-12-816475-4.00008-2

المؤلفون: Marco A. S. Baptista, Shalini Padmanabhan, Brian K. Fiske

المصدر: Cells
Cells, Vol 9, Iss 1878, p 1878 (2020)

مصطلحات موضوعية: Foundation (evidence), biomarkers, Parkinson Disease, LRRK2, General Medicine, Disease, therapeutic development, Critical research, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Collaboration, Rab, nervous system diseases, Clinical trial, Drug development, lcsh:Biology (General), rab GTP-Binding Proteins, Perspective, Animals, Humans, antibodies, Engineering ethics, genetic, Psychology, lcsh:QH301-705.5

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6702b9a94f61fa68f5e15cce3a73c951
https://pubmed.ncbi.nlm.nih.gov/32796584

المؤلفون: Paul Cannon, Kalpana M. Merchant, Jamie L. Marshall, Jung-Jin Lee, Nicola Whiffin, Danish Saleheen, Anna Guan, Tõnu Esko, Qingbo Wang, Aki S. Havulinna, Cole Whiteman, Daniel G. MacArthur, Christina M. Hultman, Carlos N. Pato, Ruth J. F. Loos, Marco A. S. Baptista, Babak Alipanahi, Mark J. Daly, Kristen M. Laricchia, Irina M. Armean, Aaron Kleinman, James S. Ware, Beryl B. Cummings, Nicholas M Quaife, Laurent C. Francioli, Lili Milani, Konrad J. Karczewski, Jessica Alföldi, Julia K. Goodrich, Patrick F. Sullivan, Genome Aggregation Database Production Team, Eric Vallabh Minikel, Peter Morrison, Aarno Palotie, Bozenna Iliadou, Joanne B. Cole, Michele T. Pato, Girish N. Nadkarni

المساهمون: Medicum, Institute for Molecular Medicine Finland, Complex Disease Genetics, University of Helsinki, Centre of Excellence in Complex Disease Genetics, Research Programs Unit, Aarno Palotie / Principal Investigator, Genomics of Neurological and Neuropsychiatric Disorders, Helsinki Institute of Life Science HiLIFE, Department of Public Health, Samuli Olli Ripatti / Principal Investigator, University Management, Biostatistics Helsinki, HUS Helsinki and Uusimaa Hospital District, Tampere University, Clinical Medicine, Department of Clinical Chemistry, Imper, Rosetrees Trust, Wellcome Trust

مصطلحات موضوعية: 0301 basic medicine, Male, ved/biology.organism_classification_rank.species, Research & Experimental Medicine, Genome, 0302 clinical medicine, PARKINSONS-DISEASE, Loss of Function Mutation, EPIDEMIOLOGY, Myocytes, Cardiac, Lymphocytes, 11 Medical and Health Sciences, Biological Specimen Banks, Genetics, Aged, 80 and over, Drug discovery, Genome Aggregation Database Production Team, Parkinson Disease, General Medicine, Middle Aged, LRRK2, 3. Good health, Phenotype, Medicine, Research & Experimental, Gain of Function Mutation, Female, Life Sciences & Biomedicine, Adult, Biochemistry & Molecular Biology, Heterozygote, Longevity, Immunology, Genomics, Biology, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, 23andMe Research Team, General Biochemistry, Genetics and Molecular Biology, Cell Line, 03 medical and health sciences, Humans, COHORT, Kinase activity, Model organism, Gene, Loss function, Embryonic Stem Cells, Aged, Science & Technology, ved/biology, Cell Biology, the 23andMe Research Team, GENE, nervous system diseases, 030104 developmental biology, Genome Aggregation Database Consortium, 1182 Biochemistry, cell and molecular biology, 3111 Biomedicine, DISEASE-ASSOCIATED MUTATIONS, 030217 neurology & neurosurgery

وصف الملف: fulltext

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c561587579bf49d7e8186937ea3476
http://hdl.handle.net/10138/317759

المؤلفون: Marco A. S. Baptista, Danielle Smith, Francesca Tonelli, Dario R. Alessi, Andrew J. M. Howden, Esther Sammler, Ying Fan, Lindsey Riley, Shalini Padmanabhan, Connie Marras

المصدر: Journal of Visualized Experiments.

مصطلحات موضوعية: 0301 basic medicine, Neutrophils, medicine.drug_class, medicine.medical_treatment, General Chemical Engineering, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Monoclonal antibody, Epitope, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Lysis buffer, medicine, Humans, Protein phosphorylation, Phosphorylation, Protease, General Immunology and Microbiology, Kinase, Chemistry, General Neuroscience, Parkinson Disease, LRRK2, nervous system diseases, Cell biology, 030104 developmental biology, rab GTP-Binding Proteins, Mutation, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14211f0dfec83767c207af7313c9098f
https://doi.org/10.3791/58956-v

المؤلفون: Nicola, Whiffin, Irina M, Armean, Aaron, Kleinman, Jamie L, Marshall, Eric V, Minikel, Julia K, Goodrich, Nicholas M, Quaife, Joanne B, Cole, Qingbo, Wang, Konrad J, Karczewski, Beryl B, Cummings, Laurent, Francioli, Kristen, Laricchia, Anna, Guan, Babak, Alipanahi, Peter, Morrison, Marco A S, Baptista, Kalpana M, Merchant, James S, Ware, Aki S, Havulinna, Bozenna, Iliadou, Jung-Jin, Lee, Girish N, Nadkarni, Cole, Whiteman, Mark, Daly, Tõnu, Esko, Christina, Hultman, Ruth J F, Loos, Lili, Milani, Aarno, Palotie, Carlos, Pato, Michele, Pato, Danish, Saleheen, Patrick F, Sullivan, Jessica, Alföldi, Paul, Cannon, Catherine H, Wilson

المصدر: Nat Med

مصطلحات موضوعية: Adult, Aged, 80 and over, Male, Heterozygote, Longevity, Parkinson Disease, Middle Aged, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Cell Line, Phenotype, Loss of Function Mutation, Gain of Function Mutation, Humans, Female, Myocytes, Cardiac, Lymphocytes, Author Correction, Embryonic Stem Cells, Aged, Biological Specimen Banks

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::54f8e9bc57dbcb7e774eee0ecdc54ecd
https://pubmed.ncbi.nlm.nih.gov/33483629