المؤلفون: Mohammad Houshmand, Nicoletta Vitale, Francesca Orso, Alessandro Cignetti, Ivan Molineris, Valentina Gaidano, Stefano Sainas, Marta Giorgis, Donatella Boschi, Carmen Fava, Alice Passoni, Marta Gai, Massimo Geuna, Federica Sora, Alessandra Iurlo, Elisabetta Abruzzese, Massimo Breccia, Olga Mulas, Giovanni Caocci, Fausto Castagnetti, Daniela Taverna, Salvatore Oliviero, Fabrizio Pane, Marco Lucio Lolli, Paola Circosta, Giuseppe Saglio

المصدر: Cell Death and Disease, Vol 13, Iss 6, Pp 1-13 (2022)

مصطلحات موضوعية: Cytology, QH573-671

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-4889

URL الوصول: https://doaj.org/article/8b9664dc6202406c8f68c1be24352acf

المؤلفون: Giulia Sibille, Anna Luganini, Stefano Sainas, Donatella Boschi, Marco Lucio Lolli, Giorgio Gribaudo

المصدر: Viruses, Vol 14, Iss 10, p 2281 (2022)

مصطلحات موضوعية: influenza virus, host-targeting antivirals, de novo pyrimidine biosynthesis, dihydroorotate dehydrogenase, MEDS433, dipyridamole, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1999-4915/14/10/2281; https://doaj.org/toc/1999-4915

URL الوصول: https://doaj.org/article/8eac384bf79446999a2cb3243736690b

المؤلفون: Arianna Calistri, Anna Luganini, Barbara Mognetti, Elizabeth Elder, Giulia Sibille, Valeria Conciatori, Claudia Del Vecchio, Stefano Sainas, Donatella Boschi, Nuria Montserrat, Ali Mirazimi, Marco Lucio Lolli, Giorgio Gribaudo, Cristina Parolin

المصدر: Microorganisms, Vol 9, Iss 8, p 1731 (2021)

مصطلحات موضوعية: coronavirus, SARS-CoV-2, pyrimidine biosynthesis, hDHODH inhibitor, antiviral activity, combination treatment, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2076-2607/9/8/1731; https://doaj.org/toc/2076-2607

URL الوصول: https://doaj.org/article/258bb6e07d254f5192a8e4e2f68eb885

المؤلفون: Elena Campaner, Alessandra Rustighi, Alessandro Zannini, Alberto Cristiani, Silvano Piazza, Yari Ciani, Ori Kalid, Gali Golan, Erkan Baloglu, Sharon Shacham, Barbara Valsasina, Ulisse Cucchi, Agnese Chiara Pippione, Marco Lucio Lolli, Barbara Giabbai, Paola Storici, Paolo Carloni, Giulia Rossetti, Federica Benvenuti, Ezia Bello, Maurizio D’Incalci, Elisa Cappuzzello, Antonio Rosato, Giannino Del Sal

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/e607d20382804710bdbe82d915bc8ddd

المؤلفون: Valentina Gaidano, Mohammad Houshmand, Nicoletta Vitale, Giovanna Carrà, Alessandro Morotti, Valerio Tenace, Stefania Rapelli, Stefano Sainas, Agnese Chiara Pippione, Marta Giorgis, Donatella Boschi, Marco Lucio Lolli, Daniela Cilloni, Alessandro Cignetti, Giuseppe Saglio, Paola Circosta

المصدر: Cancers, Vol 13, Iss 5, p 1003 (2021)

مصطلحات موضوعية: DHODH, dipyridamole, acute myeloid leukemia, apoptosis, differentiation, pyrimidine depletion, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2072-6694/13/5/1003; https://doaj.org/toc/2072-6694

URL الوصول: https://doaj.org/article/6457d0266b1f4413a61306dc30ae7316

المؤلفون: Arun Kumar, Chiara Vigato, Donatella Boschi, Marco Lucio Lolli, Deepak Kumar

مصطلحات موضوعية: Pharmacology, Phenothiazine, Anti-Cancer, SAR, Synthesis, MDR reversal, Synthesis, Organic Chemistry, Drug Discovery, Phenothiazine, Anti-Cancer, General Medicine, MDR reversal, SAR

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0760c7d425b561aedc18d316dd3dca3
https://hdl.handle.net/2318/1899572

المؤلفون: Giulia, Sibille, Anna, Luganini, Stefano, Sainas, Donatella, Boschi, Marco Lucio, Lolli, Giorgio, Gribaudo

المصدر: Viruses. 14(10)

مصطلحات موضوعية: Pyrimidines, Orthomyxoviridae Infections, Influenza, Human, Dihydroorotate Dehydrogenase, Humans, Dipyridamole, Cytidine, Enzyme Inhibitors, Virus Replication, Antiviral Agents, Uridine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::01b63e7700ba5f7f50cab82ef0a1dee8
https://pubmed.ncbi.nlm.nih.gov/36298835

المؤلفون: Marta Giorgis, Donatella Boschi, Barbara Buccinnà, Stefano Sainas, Mariia Mishina, Davide Bonanni, Alice Passoni, Salam Al-Karadaghi, Yaqi Qiu, Cristina Ramondetti, Paola Circosta, Giuseppe Saglio, Marco Piccinini, Valentina Gaidano, Mohammad Houshmand, Alessandro Bona, Alessandro Cignetti, Enrico Giraudo, Carina Florina Cojocaru, Marco Lucio Lolli, Barbara Rolando, Renzo Bagnati, Agnese Chiara Pippione, Barbara Canepa

المصدر: Journal of Medicinal Chemistry. 64:5404-5428

مصطلحات موضوعية: Myeloid, Male, Oxidoreductases Acting on CH-CH Group Donors, Pyridines, Apoptosis, Acute, Pharmacology, 01 natural sciences, Jurkat cells, Cell Line, Mice, Structure-Activity Relationship, 03 medical and health sciences, Myelogenous, Microsomes, hemic and lymphatic diseases, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Enzyme Inhibitors, Cytotoxicity, Inbred BALB C, 030304 developmental biology, Dihydroorotate Dehydrogenase Inhibitor, 0303 health sciences, Binding Sites, Tumor, Leukemia, Chemistry, Biphenyl Compounds, Cell Differentiation, medicine.disease, Rats, 0104 chemical sciences, Molecular Docking Simulation, Biphenyl compound, 010404 medicinal & biomolecular chemistry, Liver, Drug Design, Dihydroorotate dehydrogenase, Pyrazoles, Molecular Medicine, Female, Sprague-Dawley, Cell Line, Tumor, Half-Life, Leukemia, Myeloid, Acute, Mice, Inbred BALB C, Microsomes, Liver, Rats, Sprague-Dawley

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::281c81addc6474b683c17e342be6dc2c
https://doi.org/10.1021/acs.jmedchem.0c01549

المؤلفون: Martina Daga, Salvatore Adinolfi, Donald Poirier, Gianni Balliano, Giulia D'Arrigo, Simonetta Oliaro-Bosso, Marco Lucio Lolli, Francesca Spyrakis, Terenzio Ferrante

المصدر: Biochimie. 170:106-117

مصطلحات موضوعية: 0301 basic medicine, Zymosterol, HSD17B7, 3-Hydroxysteroid Dehydrogenases, Estrone, Protein Conformation, Cell Cycle Proteins, Dehydrogenase, Reductase, Molecular Dynamics, Biochemistry, 17β-Hydroxysteroid dehydrogenases, S100 Calcium Binding Protein A6, 03 medical and health sciences, chemistry.chemical_compound, Humans, Enzyme Inhibitors, Hydroxysteroid dehydrogenase, chemistry.chemical_classification, Estradiol, 030102 biochemistry & molecular biology, Inhibitors, Chemistry, Lanosterol, Estrogens, Hep G2 Cells, General Medicine, Metabolism, 4-Methylzymosterone, Cholesterol, 030104 developmental biology, Enzyme, Steroids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85b93caf0fa7832c811e0126a9a365d
https://doi.org/10.1016/j.biochi.2019.12.012

المؤلفون: Arianna, Calistri, Anna, Luganini, Barbara, Mognetti, Elizabeth, Elder, Giulia, Sibille, Valeria, Conciatori, Claudia, Del Vecchio, Stefano, Sainas, Donatella, Boschi, Nuria, Montserrat, Ali, Mirazimi, Marco Lucio, Lolli, Giorgio, Gribaudo, Cristina, Parolin

المصدر: Microorganisms

مصطلحات موضوعية: SARS-CoV-2, hDHODH inhibitor, viruses, coronavirus, antiviral activity, combination treatment, virus diseases, broad-spectrum antiviral, pyrimidine biosynthesis, Article, organoids, respiratory tract diseases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::3184b9c9f852701315d72b699e2cf2f9
https://pubmed.ncbi.nlm.nih.gov/34442810