المؤلفون: Florian Märkl, Christoph Schultheiß, Murtaza Ali, Shih-Shih Chen, Marina Zintchenko, Lukas Egli, Juliane Mietz, Obinna Chijioke, Lisa Paschold, Sebastijan Spajic, Anne Holtermann, Janina Dörr, Sophia Stock, Andreas Zingg, Heinz Läubli, Ignazio Piseddu, David Anz, Marcus Dühren-von Minden, Tianjiao Zhang, Thomas Nerreter, Michael Hudecek, Susana Minguet, Nicholas Chiorazzi, Sebastian Kobold, Mascha Binder

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/f556d70ecba646069501e54817da7995

المؤلفون: Andrea N. Mazzarello, Eva Gentner-Göbel, Marcus Dühren-von Minden, Tatyana N. Tarasenko, Antonella Nicolò, Gerardo Ferrer, Stefano Vergani, Yun Liu, Davide Bagnara, Kanti R. Rai, Jan A. Burger, Peter J. McGuire, Palash C. Maity, Hassan Jumaa, Nicholas Chiorazzi

المصدر: The Journal of Clinical Investigation, Vol 132, Iss 2 (2022)

مصطلحات موضوعية: Immunology, Oncology, Medicine

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1558-8238

URL الوصول: https://doaj.org/article/66a5d21ed217411b9bb0675bdc0e82e4

المؤلفون: Claudia Minici, Maria Gounari, Rudolf Übelhart, Lydia Scarfò, Marcus Dühren-von Minden, Dunja Schneider, Alpaslan Tasdogan, Alabbas Alkhatib, Andreas Agathangelidis, Stavroula Ntoufa, Nicholas Chiorazzi, Hassan Jumaa, Kostas Stamatopoulos, Paolo Ghia, Massimo Degano

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/d134c066cc4e4ceb916cfd21f5f03500

المؤلفون: Dimitrios Papaioannou, Anna-Maria Strothmeyer, Marcus Dühren-von Minden, Andrea Keppler-Hafkemeyer, Katja Zirlik, Kristina Mikesch, Cornelis A.M. van Bergen, Marcelo A. Navarrete, Hendrik Veelken

المصدر: Haematologica, Vol 100, Iss 4 (2015)

مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5

وصف الملف: electronic resource

Relation: https://haematologica.org/article/view/7356; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

URL الوصول: https://doaj.org/article/b7f60b95b02a4856a536940287c5612d

المؤلفون: Antonella Nicolò, Davide Bagnara, Eva Gentner-Göbel, Marcus Dühren-von Minden, Stefano Vergani, Gerardo Ferrer, Kanti R. Rai, Andrea Nicola Mazzarello, Hassan Jumaa, Jan A. Burger, Nicholas Chiorazzi, Yun Liu, Tatyana N. Tarasenko, Peter J. McGuire, Palash Chandra Maity

المساهمون: European Union (EU), Horizon 2020

المصدر: The Journal of Clinical Investigation
Journal of Clinical Investigation

مصطلحات موضوعية: SURFACE IGM EXPRESSION, Male, ZAP-70, SUBSETS, Chronic lymphocytic leukemia, Signal transduction, Immunoglobulin D, DISEASE, Mice, 0302 clinical medicine, immune system diseases, hemic and lymphatic diseases, Leukemia, Lymphocytic, Chronic, B-Cell, Drug therapy, Receptors, Chronic, IBRUTINIB, Receptor, Mice, Knockout, B-Lymphocytes, 0303 health sciences, Leukemia, ANTIGEN RECEPTORS, Immunoglobulins, Immunology, Leukemias, Oncology, Mouse Models, Humans, Immunoglobulin M, Receptors, Antigen, B-Cell, Signal Transduction, BCR, CLL, PROLIFERATION, breakpoint cluster region, General Medicine, Lymphocytic, 3. Good health, Antigen, 030220 oncology & carcinogenesis, Chronisch-lymphatische Leukämie, Female, Antibody, Research Article, Cell signaling, Knockout, B-cell receptor, METABOLISM, Biology, 03 medical and health sciences, Protein kinase inhibitors, Therapeutic use, medicine, Animals, ddc:610, Chemotherapie, 030304 developmental biology, B-Cell, B-Lymphozyten-Rezeptor, medicine.disease, Receptors, Antigen, Cancer research, biology.protein, INDICATE, GENE MUTATION STATUS, DDC 610 / Medicine & health

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc6a1a27d35975afb9ac6cd89e54678
https://doi.org/10.1172/jci149308

المؤلفون: Maike Buchner, Giovanni Cazzaniga, Valeria Cazzaniga, Seyedmehdi Shojaee, Andreas Hochhaus, Hong Wu, Hassan Jumaa, Yihua Qiu, Ari Melnick, Markus Müschen, Thomas G. Graeber, Kadriye Nehir Cosgun, Steven M. Kornblau, Lai N. Chan, Thomas Ernst, Marcus Dühren-von Minden, Huimin Geng

المساهمون: Shojaee, S, Chan, L, Buchner, M, Cazzaniga, V, Cosgun, K, Geng, H, Qiu, Y, Von Minden, M, Ernst, T, Hochhaus, A, Cazzaniga, G, Melnick, A, Kornblau, S, Graeber, T, Wu, H, Jumaa, H, Müschen, M

المصدر: Nature medicine, vol 22, iss 4
Shojaee, S; Chan, LN; Buchner, M; Cazzaniga, V; Cosgun, KN; Geng, H; et al.(2016). PTEN opposes negative selection and enables oncogenic transformation of pre-B cells. Nature Medicine, 22(4), 379-387. doi: 10.1038/nm.4062. UCSF: Retrieved from: http://www.escholarship.org/uc/item/50p8r92k

مصطلحات موضوعية: 0301 basic medicine, Cell cycle checkpoint, MED/03 - GENETICA MEDICA, Drug Resistance, Medical and Health Sciences, Transgenic, Mice, Phosphatidylinositol 3-Kinases, 2.1 Biological and endogenous factors, Tensin, Cancer, Pediatric, B-Lymphocytes, Tumor, B-Lymphocyte, Hematology, General Medicine, 3. Good health, Leukemia, Pre-B Cell Receptors, Signal transduction, Pre-B Cell Receptor, Human, Signal Transduction, Cell signaling, Childhood Leukemia, Pediatric Cancer, 1.1 Normal biological development and functioning, Immunology, Mice, Transgenic, Biology, General Biochemistry, Genetics and Molecular Biology, Cell Line, 03 medical and health sciences, Rare Diseases, Cell Line, Tumor, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, medicine, Animals, Humans, PTEN, Protein kinase B, PI3K/AKT/mTOR pathway, Biochemistry, Genetics and Molecular Biology (all), Animal, PTEN Phosphohydrolase, medicine.disease, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer research, biology.protein, Neoplasm, Phosphatidylinositol 3-Kinase, Proto-Oncogene Proteins c-akt

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::327ebde0b0ca5cd89a3440f52bad1ccd
https://doi.org/10.1038/nm.4062

المؤلفون: Marcus Dühren-von Minden, Michael Reth, Thomas Wossning, Martina P. Bach, Kohei Kometani, Hassan Jumaa, Anselm H. C. Horn, Rudolf Übelhart, Tomohiro Kurosaki, Eva Hug, Christoph J. Binder, Dimitrios Tsiantoulas, Heinrich Sticht, Lars Nitschke

المصدر: Nature Immunology. 16:534-543

مصطلحات موضوعية: Cellular differentiation, Immunology, chemical and pharmacologic phenomena, Antigen-Antibody Complex, Protein Engineering, Immunoglobulin D, Cell Line, Mice, Immune system, stomatognathic system, Antigen, hemic and lymphatic diseases, medicine, Animals, Homeostasis, Immunology and Allergy, Calcium Signaling, Antigens, Receptor, Hinge Exons, B cell, Sequence Deletion, Mice, Knockout, B-Lymphocytes, biology, Cell Differentiation, Molecular biology, Immunity, Humoral, B-1 cell, medicine.anatomical_structure, Immunoglobulin M, biology.protein, Binding Sites, Antibody

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4008f32625c3b509f6c38a56cf348193
https://doi.org/10.1038/ni.3141

المؤلفون: Cristina Bertinetti-Lapatki, Katja Zirlik, Kristina Mikesch, Marcelo A. Navarrete, Marlon van der Burgt, Szymon M. Kielbasa, Hendrik Veelken, Liesbeth C. de Wreede, Florian Scherer, Marcus Dühren-von Minden

المصدر: British Journal of Haematology, 175(5), 972-975

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, B-cell receptor, Follicular lymphoma, Somatic hypermutation, Receptors, Antigen, B-Cell, 03 medical and health sciences, follicular lymphoma, Medicine, Humans, Lymphoma, Follicular, Selection (genetic algorithm), Aged, B-Lymphocytes, biology, business.industry, immune selection, Hematology, Middle Aged, medicine.disease, somatic hypermutation, Natural history, 030104 developmental biology, Immune selection, Immunology, biology.protein, Female, Antibody, business, immunoglobulin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be57aecb6fb8b5c188b5c70b32ef78de
http://hdl.handle.net/1887/113713

المؤلفون: Rainer Claus, Justus Duyster, Marcus Dühren-von-Minden, Christine Dierks, Kathrin Kläsener, Maike Buchner, Kerstin Leberecht, Hassan Jumaa, Fabio Malavasi, Marco Benkisser-Petersen, Arlette Dörffel, Hendrik Veelken, Meike Burger, Katja Zirlik, Michael Reth

المصدر: PLoS ONE, Vol 11, Iss 12, p e0169159 (2016)
PLoS One
PLoS ONE
PLoS ONE, 11(12)

مصطلحات موضوعية: 0301 basic medicine, Male, Cell signaling, B Cells, R406 inhibited, Pyridines, Chronic lymphocytic leukemia, Syk, lcsh:Medicine, Apoptosis, CD38, Signal transduction, ERK signaling cascade, Biochemistry, Receptor tyrosine kinase, Hematologic Cancers and Related Disorders, White Blood Cells, 0302 clinical medicine, Spectrum Analysis Techniques, Animal Cells, Cell Movement, immune system diseases, hemic and lymphatic diseases, Medicine and Health Sciences, Tumor Cells, Cultured, SYK, Post-Translational Modification, Phosphorylation, Ligation Assay, Extracellular Signal-Regulated MAP Kinases, lcsh:Science, Chronic Lymphoblastic Leukemia, Aged, 80 and over, Multidisciplinary, Membrane Glycoproteins, biology, Cell Death, Chemistry, Signaling cascades, hemic and immune systems, Hematology, Middle Aged, Flow Cytometry, Cell Motility, Oncology, Spectrophotometry, Cell Processes, Lymphoblastic Leukemia, Female, Cytophotometry, Cellular Types, Research Article, Adult, Cell Survival, Immune Cells, Immunology, Cell Migration, Research and Analysis Methods, 03 medical and health sciences, Downregulation and upregulation, Leukemias, Oxazines, medicine, Humans, Syk Kinase, ddc:610, SYK, AKT, CD38, R406 inhibited, Antibody-Producing Cells, Molecular Biology Techniques, Protein kinase B, Molecular Biology, neoplasms, Aged, Molecular Biology Assays and Analysis Techniques, Blood Cells, AKT, lcsh:R, Cancers and Neoplasms, Biology and Life Sciences, Proteins, Cell Biology, medicine.disease, ADP-ribosyl Cyclase 1, Leukemia, Lymphocytic, Chronic, B-Cell, Chemokine CXCL12, 030104 developmental biology, biology.protein, Cancer research, Myeloid Cell Leukemia Sequence 1 Protein, lcsh:Q, Proto-Oncogene Proteins c-akt, 030215 immunology, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d291812eb97c055e488c3b8b2968dd
http://europepmc.org/articles/PMC5201248?pdf=render

المؤلفون: Marcus Dühren-von Minden, Rudolf Übelhart, Dunja Schneider, Thomas Wossning, Martina P. Bach, Maike Buchner, Daniel Hofmann, Elena Surova, Marie Follo, Fabian Köhler, Hedda Wardemann, Katja

المصدر: Nature, Nature. 489(7415):309-312

الإتاحة: https://ideas.repec.org/a/nat/nature/v489y2012i7415d10.1038_nature11309.html