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1دورية أكاديمية
المؤلفون: Marek M Nagiec, Adam P Skepner, Joseph Negri, Michelle Eichhorn, Nicolas Kuperwasser, Eamon Comer, Giovanni Muncipinto, Aravind Subramanian, Clary Clish, Kiran Musunuru, Jeremy R Duvall, Michael Foley, Jose R Perez, Michelle A J Palmer
المصدر: PLoS ONE, Vol 10, Iss 3, p e0120295 (2015)
وصف الملف: electronic resource
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المؤلفون: Marek M, Nagiec, Jeremy R, Duvall, Adam P, Skepner, Eleanor A, Howe, Jessica, Bastien, Eamon, Comer, Jean-Charles, Marie, Stephen E, Johnston, Joseph, Negri, Michelle, Eichhorn, Julien, Vantourout, Clary, Clish, Kiran, Musunuru, Michael, Foley, Jose R, Perez, Michelle A J, Palmer
المصدر: MedChemComm. 9(11)
مصطلحات موضوعية: Chemistry, lipids (amino acids, peptides, and proteins)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::22e105aa4f33d9ef4ee264e0519ebeba
https://pubmed.ncbi.nlm.nih.gov/30542533 -
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المؤلفون: Maureen K. Highkin, Matthew D. McReynolds, Matthew J. Saabye, John W. Rains, Kaliapan Iyanar, Jeffrey Carroll, Jill Chrencik, Matthew P. Yates, Jeffrey A. Scholten, Gina M. Jerome, Marek M. Nagiec, Mark E. Schnute
المصدر: Journal of medicinal chemistry. 60(6)
مصطلحات موضوعية: 0301 basic medicine, Agonist, Models, Molecular, Pyrrolidines, medicine.drug_class, Sphingosine kinase, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, medicine, Humans, IC50, Protein Kinase Inhibitors, Amination, biology, Cell growth, Drug discovery, Chemistry, Lipid signaling, SPHK2, Phosphotransferases (Alcohol Group Acceptor), 030104 developmental biology, Biochemistry, Sphingosine kinase 1, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, Benzimidazoles
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المؤلفون: Stuart L. Schreiber, Michael Foley, Andrew Germain, Willmen Youngsaye, Timothy A. Lewis, Lawrence MacPherson, Michelle Palmer, Marek M. Nagiec, Christina Scherer, Han-Je Kim, Partha P. Nag, Michel Weïwer, BenjaminZ. Stanton, Chris Dockendorff, Melissa Bennion, Amal Ting, Jose Perez, Sara J. Buhrlage, Linlong Xue
المصدر: ACS Medicinal Chemistry Letters
مصطلحات موضوعية: Purmorphamine, Patched, Letter, Stereochemistry, 010402 general chemistry, 01 natural sciences, Biochemistry, C3H10T1/2, GLI1, Drug Discovery, Mode of action, Hedgehog, Smoothened antagonist, Sonic Hedgehog pathway, biology, 010405 organic chemistry, Organic Chemistry, Combinatorial chemistry, Hedgehog signaling pathway, 0104 chemical sciences, 3. Good health, biology.protein, Alkaline phosphatase, macrocycle, Smoothened, diversity-oriented synthesis (DOS)
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المؤلفون: Michelle Kraus, Jay M. Wendling, Olga V. Nemirovskiy, John W. Rains, Vincent Peterkin, Laura E. Zawadzke, Hideji Fujiwara, Ciarán N. Cronin, Troii Hall, Tom Kasten, Maureen K. Highkin, Gina M. Jerome, Arthur J. Wittwer, Matthew P. Yates, Shinji Ogawa, Jeffrey A. Scholten, Jill Chrencik, Marek M. Nagiec, Matthew D. McReynolds, Kaliapan Iyanar, Mark E. Schnute, Kristin Cukyne, Matthew J. Saabye, Richard M. Broadus
المصدر: Biochemical Journal. 444:79-88
مصطلحات موضوعية: Cell Membrane Permeability, Pyrrolidines, Sphingosine kinase, Biochemistry, Substrate Specificity, chemistry.chemical_compound, Sphingosine, Cell Line, Tumor, Humans, Sulfones, Phosphorylation, Receptor, Molecular Biology, G protein-coupled receptor, biology, Cell growth, Methanol, Cell Biology, Cell biology, Phosphotransferases (Alcohol Group Acceptor), SPHK2, Sphingosine kinase 1, chemistry, Cell culture, biology.protein, lipids (amino acids, peptides, and proteins), Lysophospholipids
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c29039f87435103ee01d57e1663842f
https://doi.org/10.1042/bj20111929 -
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المؤلفون: Olga V. Nemirovskiy, Jaime L. Masferrer, Grace E. Munie, William A. LaMarr, Maureen K. Highkin, John W. Rains, Marek M. Nagiec, Matthew P. Yates
المصدر: SLAS Discovery. 16:272-277
مصطلحات موضوعية: Sphingosine metabolism, High-throughput screening, Sphingosine kinase, Aminophenols, Mass spectrometry, Biochemistry, Mass Spectrometry, Analytical Chemistry, chemistry.chemical_compound, Sphingosine, High-Throughput Screening Assays, Humans, Enzyme Inhibitors, Whole blood, Chromatography, Dose-Response Relationship, Drug, Kinetics, Phosphotransferases (Alcohol Group Acceptor), Thiazoles, chemistry, Homogeneous, Molecular Medicine, lipids (amino acids, peptides, and proteins), Lysophospholipids, Signal Transduction, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e0fed6a3d09dfcbd8fa986e16ef53b
https://doi.org/10.1177/1087057110391656 -
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المؤلفون: Paul A. Aeed, Andrea E. Sperry, Åke P. Elhammer, Casey L. Young, Marek M. Nagiec
المصدر: Biochemistry. 43:8483-8493
مصطلحات موضوعية: Time Factors, Octoxynol, Detergents, Polidocanol, Polysorbates, Butyrate, Ceramides, Biochemistry, Polyethylene Glycols, chemistry.chemical_compound, Glucosides, Candida albicans, Centrifugation, Density Gradient, Inositol, Phosphatidylinositol, Phospholipids, chemistry.chemical_classification, Chromatography, Taurodeoxycholic Acid, Dose-Response Relationship, Drug, ATP synthase, biology, Molecular mass, Cholic Acids, biology.organism_classification, Lipids, Quaternary Ammonium Compounds, Butyrates, Kinetics, 4-Chloro-7-nitrobenzofurazan, Enzyme, Membrane, Hexosyltransferases, chemistry, biology.protein, Cetomacrogol, Lysophospholipids
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المصدر: Biochemical and Biophysical Research Communications. 307:369-374
مصطلحات موضوعية: Antifungal Agents, Saccharomyces cerevisiae Proteins, Saccharomyces cerevisiae, Mutant, Biophysics, Microbial Sensitivity Tests, Cycloheximide, Biochemistry, chemistry.chemical_compound, Myriocin, Inositol, Molecular Biology, Sphingolipids, Molecular Structure, biology, ATP synthase, Serine C-palmitoyltransferase, Dyneins, Cell Biology, biology.organism_classification, Sphingolipid, chemistry, Mutation, biology.protein, Acyltransferases
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المؤلفون: Marek M. Nagiec, Scott D. Kobayashi
المصدر: Eukaryotic Cell. 2:284-294
مصطلحات موضوعية: Ceramide, Saccharomyces cerevisiae Proteins, Saccharomyces cerevisiae, Protein Serine-Threonine Kinases, Biology, Ceramides, Microbiology, Gene Expression Regulation, Enzymologic, Phosphates, chemistry.chemical_compound, Acetyltransferases, Drug Resistance, Fungal, Kinase activity, Casein Kinase II, Growth Substances, Protein kinase A, Molecular Biology, Ceramide synthase, Cells, Cultured, Sphingolipids, Articles, General Medicine, Lipid signaling, Sphingolipid, Phosphoric Monoester Hydrolases, chemistry, Biochemistry, Mutation, Fatty acid elongation, lipids (amino acids, peptides, and proteins), Genes, Lethal, Acyl Coenzyme A, Casein kinase 2
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad28b9cf50566004d8fe6a004984826
https://doi.org/10.1128/ec.2.2.284-294.2003 -
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المؤلفون: Kiran Musunuru, Adam Skepner, Marek M. Nagiec, Clary B. Clish, Aravind Subramanian, Michelle Eichhorn, Joseph Negri, Michelle Palmer, Jeremy R. Duvall, José Carlos Rodríguez Pérez, Eamon Comer, Michael Foley, Giovanni Muncipinto
المصدر: The FASEB Journal. 28
مصطلحات موضوعية: Biochemistry, Genetics, Inducer, Lipoprotein metabolism, Biology, Molecular Biology, Small molecule, Reprogramming, Biotechnology, Cell biology