المؤلفون: Maria Dumitrascuta, Charlotte Martin, Steven Ballet, Mariana Spetea

المصدر: Molecules, Vol 27, Iss 24, p 8785 (2022)

مصطلحات موضوعية: multifunctional ligands, mu-opioid receptor, neuropeptide FF receptors, G protein-biased-opioid agonist, pain, opioid analgesia, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/24/8785; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/9931d7c9ca14407e88471dc1a03c3718

المؤلفون: Maria Dumitrascuta, Marcel Bermudez, Olga Trovato, Jolien De Neve, Steven Ballet, Gerhard Wolber, Mariana Spetea

المصدر: Molecules, Vol 26, Iss 11, p 3267 (2021)

مصطلحات موضوعية: µ-opioid receptor, nociceptin receptor, multitarget ligands, inflammatory pain, side effects, reward, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/11/3267; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/cf0ea917f0194797b4d8986faa2d4631

المؤلفون: Maria Dumitrascuta, Marcel Bermudez, Steven Ballet, Gerhard Wolber, Mariana Spetea

المصدر: Molecules, Vol 25, Iss 9, p 2087 (2020)

مصطلحات موضوعية: mu opioid receptor, opioid peptides and peptidomimetics, DAMGO, DALDA, [Dmt1]DALDA, KGOP01, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/9/2087; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/85cd8759a62b46fa8adb6ffb1d6cb1a5

المؤلفون: Simon Gonzalez, Dirk Tourwé, Philippe Sarret, Mariana Spetea, Florine Cavelier, Santo Previti, Charlotte Martin, Linda Kunze, Mélanie Vivancos, Stevany Louis, Louis Gendron, Elke Dewolf, Maria Dumitrascuta, Steven Ballet, Emilie Eiselt, Annalisa Blasiol

المساهمون: Chemistry, Faculty of Economic and Social Sciences and Solvay Business School, WE Academic Unit, Vriendenkring VUB, High Resolution NMR Centre, Organic Chemistry, Vrije Universiteit Brussel [Bruxelles] (VUB), University of Innsbruck, Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Université de Sherbrooke (UdeS)

المصدر: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2020, 63 (21), pp.12929-12941. ⟨10.1021/acs.jmedchem.0c01376⟩

مصطلحات موضوعية: Agonist, Male, medicine.drug_class, Stereochemistry, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Receptors, Opioid, mu, Pain, Peptide, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, 01 natural sciences, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Receptors, Opioid, delta, Drug Discovery, medicine, Structure–activity relationship, Animals, Humans, Receptors, Neurotensin, Amino Acid Sequence, Receptor, Peptide sequence, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Tetrapeptide, Chemistry, 0104 chemical sciences, Amino acid, 010404 medicinal & biomolecular chemistry, Disease Models, Animal, Drug Design, Molecular Medicine, Peptides, Oligopeptides, Neurotensin, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d847dbf764c975a594956d0282309fc
https://biblio.vub.ac.be/vubir/optimized-opioidneurotensin-multitarget-peptides-from-design-to-structureactivity-relationship-studies(b5565787-3be0-4e48-8dac-9092ed30584e).html

المؤلفون: Nanna B. Finnerup, Wenlong Huang, Roger G. Pertwee, Yuting Wei, Marieta Georgieva, Maria Dumitrascuta

المصدر: Georgieva, M, Wei, Y, Dumitrascuta, M, Pertwee, R, Finnerup, N B & Huang, W 2019, ' Fatty acid suppression of glial activation prevents central neuropathic pain after spinal cord injury ', Pain, vol. 160, no. 12, pp. 2724-2742 . https://doi.org/10.1097/j.pain.0000000000001670

مصطلحات موضوعية: Male, medicine.medical_specialty, Spinal Cord Dorsal Horn, Neurology, Docosahexaenoic Acids, Pharmacology, Motor Activity, Microgliosis, Neuroprotection, 03 medical and health sciences, 0302 clinical medicine, 030202 anesthesiology, medicine, Animals, Rats, Wistar, Spinal cord injury, Spinal Cord Injuries, Pain Measurement, Thigmotaxis, Behavior, Animal, business.industry, medicine.disease, Rats, Disease Models, Animal, Anesthesiology and Pain Medicine, medicine.anatomical_structure, Docosahexaenoic acid, Hyperalgesia, Neuropathic pain, Neuralgia, Neurology (clinical), Microglia, business, 030217 neurology & neurosurgery, Astrocyte

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2475aa083325561f5c6e7c5dfb72a48
https://pure.au.dk/portal/da/publications/fatty-acid-suppression-of-glial-activation-prevents-central-neuropathic-pain-after-spinal-cord-injury(5b964788-e355-4dc7-9e18-4086aa383427).html

المؤلفون: Marieta Georgieva, Wenlong Huang, Alasdair Leeson-Payne, Maria Dumitrascuta, Marzia Malcangio, Ann M. Rajnicek

المصدر: Georgieva, M, Leeson-Payne, A, Dumitrascuta, M, Rajnicek, A, Malcangio, M & Huang, W 2018, ' A refined rat primary neonatal microglial culture method that reduces time, cost and animal use ', Journal of Neuroscience Methods . https://doi.org/10.1016/j.jneumeth.2018.04.017

مصطلحات موضوعية: Male, 0301 basic medicine, Time Factors, Primary Cell Culture, microglia, Bioinformatics, Time cost, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Rats, Wistar, Laboratory research, Cells, Cultured, Animal use, Cerebral Cortex, cell culture, neonatal rats, Microglia, tissue culture dish, business.industry, General Neuroscience, Neurodegeneration, in vitro, medicine.disease, Rats, cortex, 030104 developmental biology, medicine.anatomical_structure, Animals, Newborn, Cell culture, Female, business, Cell activation, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7af3067b21b104280bb706ed6e0ec82
https://doi.org/10.1016/j.jneumeth.2018.04.017

المؤلفون: Maria Dumitrascuta, Dominik Bucher, Katja Walker, Mariana Spetea, Ann Van Eeckhaut, Morgane Mannes, Sophie Hernot, Yannick Van Wanseele, Richard Hoogenboom, Aquilino Lantero, Edith Oyen, Annemieke Madder, Charlotte Martin, Steven Ballet

المساهمون: Chemistry, WE Academic Unit, Faculty of Sciences and Bioengineering Sciences, Faculty of Medicine and Pharmacy, Experimental Pharmacology, Pharmaceutical and Pharmacological Sciences, Clinical sciences, Supporting clinical sciences, Medical Imaging

المصدر: JOURNAL OF MEDICINAL CHEMISTRY

مصطلحات موضوعية: 0301 basic medicine, Drug, Agonist, medicine.drug_class, media_common.quotation_subject, Peptide, 02 engineering and technology, Pharmacology, complex mixtures, 03 medical and health sciences, Mice, Drug Stability, EPIDEMIC, ANTINOCICEPTION, Amphiphile, Drug Discovery, medicine, Animals, Humans, Amino Acid Sequence, Opioid peptide, DALDA ANALOGS, media_common, chemistry.chemical_classification, Drug Carriers, RECEPTOR, POTENT, Chronic pain, technology, industry, and agriculture, Biology and Life Sciences, Hydrogels, 021001 nanoscience & nanotechnology, medicine.disease, Chemistry, AGONIST, 030104 developmental biology, chemistry, Opioid Peptides, Self-healing hydrogels, Drug delivery, Molecular Medicine, LIGANDS, 0210 nano-technology, CHRONIC PAIN MANAGEMENT, Hydrophobic and Hydrophilic Interactions, Oligopeptides

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b9ef388a0d259fe5b7b69cf38f963d
https://pubmed.ncbi.nlm.nih.gov/30351003

المؤلفون: Maria Dumitrascuta

المصدر: Intrinsic Activity. 7:A2.3

مصطلحات موضوعية: Opioid, business.industry, Modulation, SAFER, Medicine, Neuropeptide FF, Pharmacology, DUAL (cognitive architecture), business, Receptor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::448c95dfdef40b424a5ac63f5e02c5e2
https://doi.org/10.25006/ia.7.s1-a2.3

المؤلفون: Armand Drieu la Rochelle, Karel Guillemyn, Maria Dumitrascuta, Simon Gonzalez, Charlotte Martin, Valérie Utard, Raphaëlle Quillet, Séverine Schneider, François Daubeuf, Tom Willemse, Pieter Mampuys, Bert Maes, Nelly Frossard, Frédéric Bihel, Mariana Spetea, Frédéric Simonin, Steven Ballet

المصدر: Proceedings of the 35th European Peptide Symposium.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::28e460041c9693c2d8f842accf199b30
https://doi.org/10.17952/35eps.2018.276

المؤلفون: Steven Ballet, Armand Drieu la Rochelle, Pieter Mampuys, Valérie Utard, Frédéric Bihel, Séverine Schneider, Mariana Spetea, François Daubeuf, Karel Guillemyn, Tom Willemse, Maria Dumitrascuta, Nelly Frossard, Bert U. W. Maes, Raphaëlle Quillet, Charlotte Martin, Frédéric Simonin

المساهمون: Biotechnologie et signalisation cellulaire (BSC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut de recherche de l'Ecole de biotechnologie de Strasbourg (IREBS), CHU Toulouse [Toulouse], Laboratoire d'Innovation Thérapeutique (LIT), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC), department of chemistry, University of Antwerp (UA), Inflammation et environnement dans l'asthme, Université Louis Pasteur - Strasbourg I-Faculté de Pharmacie, Institut de génétique et biologie moléculaire et cellulaire (IGBMC), Université Louis Pasteur - Strasbourg I-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Faculty of Sciences and Bioengineering Sciences, Chemistry, WE Academic Unit

المصدر: Pain
PAIN
PAIN, Elsevier, 2018, 159 (9), pp.1705-1718. ⟨10.1097/j.pain.0000000000001262⟩

مصطلحات موضوعية: Male, Pain Threshold, Receptors, Neuropeptide, 0301 basic medicine, Agonist, medicine.drug_class, Physical dependence, [SDV]Life Sciences [q-bio], Analgesic, Receptors, Opioid, mu, Pain, Neuropeptide FF receptor, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, Motor Activity, Pharmacology, opioid receptors, Mice, 03 medical and health sciences, RF-amide peptides, 0302 clinical medicine, Opioid analgesia, NPFF receptors, Analgesic tolerance, Animals, Humans, Medicine, Neuropeptide FF, Opioid-induced hyperalgesia, ComputingMilieux_MISCELLANEOUS, business.industry, Sciences du Vivant [q-bio]/Biotechnologies, 3. Good health, Analgesics, Opioid, Chemistry, HEK293 Cells, 030104 developmental biology, Anesthesiology and Pain Medicine, Neurology, Opioid, Hyperalgesia, Neurology (clinical), Human medicine, medicine.symptom, Respiratory Insufficiency, business, Oxycodone, 030217 neurology & neurosurgery, medicine.drug

وصف الملف: pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c453b72695ed1438ea7ad7e1b1b004b1
https://hdl.handle.net/10067/1506770151162165141