المؤلفون: Daniela Presa, Syed A. Khurram, Amir Z. A. Zubir, Sneha Smarakan, Patricia A. Cooper, Goreti R. Morais, Maria Sadiq, Mark Sutherland, Paul M. Loadman, James McCaul, Steven D. Shnyder, Laurence H. Patterson, Klaus Pors

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/4ea9b86b01fd4ec18d301c0d665c1e69

المؤلفون: Muhammad Arshad, Fawwad Jaskani, Muhammad Sabri, Fatima Ashraf, Muhammad Farhan, Maria Sadiq, Hammad Raza

المصدر: EAI Endorsed Transactions on Internet of Things, Vol 7, Iss 26 (2022)

مصطلحات موضوعية: machine learning, knn, svm, human activity recognition, Computer engineering. Computer hardware, TK7885-7895, Industrial engineering. Management engineering, T55.4-60.8

وصف الملف: electronic resource

Relation: https://eudl.eu/pdf/10.4108/eai.26-5-2021.170006; https://doaj.org/toc/2414-1399

URL الوصول: https://doaj.org/article/78b54a4ee28c460d91831c212caf56af

المؤلفون: Luca Quattrini, Maria Sadiq, Giovanni Petrarolo, Norman J. Maitland, Fiona M. Frame, Klaus Pors, Concettina La Motta

المصدر: Biomedicines, Vol 8, Iss 12, p 569 (2020)

مصطلحات موضوعية: prostate cancer, aldehyde dehydrogenase, ALDH1A1, ALDH1A3, ALDH inhibitors, imidazo[1,2-a]pyridines, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2227-9059/8/12/569; https://doaj.org/toc/2227-9059

URL الوصول: https://doaj.org/article/b8594ba6e5654b259ad55760883fe350

المؤلفون: Ali I. M. Ibrahim, Elisabet Batlle, Smarakan Sneha, Rafael Jiménez, Raquel Pequerul, Xavier Parés, Till Rüngeler, Vibhu Jha, Tiziano Tuccinardi, Maria Sadiq, Fiona Frame, Norman J. Maitland, Jaume Farrés, Klaus Pors

المصدر: Journal of Medicinal Chemistry. 65:3833-3848

مصطلحات موضوعية: Male, Benzaldehydes, Drug Discovery, Humans, Prostatic Neoplasms, Molecular Medicine, Aldehyde Dehydrogenase

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afaeea21d5090735ad972cdce93e8fa
https://doi.org/10.1021/acs.jmedchem.1c01367

المؤلفون: Laurence H. Patterson, James McCaul, Sneha Smarakan, Daniela Presa, Klaus Pors, Amir Zaki Abdullah Zubir, Syed Ali Khurram, Maria Sadiq, Paul M. Loadman, Mark Sutherland, Patricia A. Cooper, Goreti Ribeiro Morais, Steven D. Shnyder

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)

مصطلحات موضوعية: Indoles, CYP1B1, Science, Antineoplastic Agents, Cohort Studies, Mice, chemistry.chemical_compound, In vivo, Cell Line, Tumor, Cytochrome P-450 CYP1A1, Animals, Humans, Prodrugs, Pyrroles, Cytochrome P450 Family 2, Carcinogen, Duocarmycin, Multidisciplinary, biology, Chemistry, Cytochrome P450, Prodrug, Xenograft Model Antitumor Assays, Head and Neck Neoplasms, Cell culture, Cytochrome P-450 CYP1B1, Cancer research, biology.protein, Medicine, Female, CYP2W1, Heterocyclic Compounds, 3-Ring

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8699e8b1784751673081ee4c59f249c
https://doaj.org/article/4ea9b86b01fd4ec18d301c0d665c1e69

المؤلفون: Elisabet Batlle Rocafort, Ali I. Ibrahim, Maria Sadiq, Sneha Smarakan, Vibhu Jha, Tiziano Tuccinardi, Fiona Frame, Norman Maitland, Rafael Jiménez Aguilar, Raquel Pequerul Pavón, Xavier Parés Casampera, Goreti Ribeiro Morais, Jaume Farrés Vicen, Klaus Pors

المصدر: Cancer Research. 82:1820-1820

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3da5b50c5786c6077e9a7b811db88467
https://doi.org/10.1158/1538-7445.am2022-1820

المؤلفون: Concettina La Motta, Fiona M. Frame, Norman J. Maitland, Maria Sadiq, Giovanni Petrarolo, Luca Quattrini, Klaus Pors

المصدر: Biomedicines
Volume 8
Issue 12
Biomedicines, Vol 8, Iss 569, p 569 (2020)

مصطلحات موضوعية: 0301 basic medicine, Population, Medicine (miscellaneous), Aldehyde dehydrogenase, Malignancy, General Biochemistry, Genetics and Molecular Biology, Article, ALDH inhibitors, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, aldehyde dehydrogenase, Prostate, imidazo[1,2-a]pyridines, Medicine, education, ALDH1A3, lcsh:QH301-705.5, ALDH1A1, education.field_of_study, biology, business.industry, Bone metastasis, medicine.disease, prostate cancer, 030104 developmental biology, medicine.anatomical_structure, lcsh:Biology (General), Cell culture, 030220 oncology & carcinogenesis, biology.protein, Cancer research, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e1cc017990734b2fabb03976489cd7
http://europepmc.org/articles/PMC7761903

المؤلفون: Roger M. Phillips, Richard T. Wheelhouse, Christopher Dunnill, Nikolaos T. Georgopoulos, Steve D. Shnyder, Efstathia Baronou, Ayse Latif, Simon J. Allison, Maria Sadiq, Ian J. Stratford, Charlotte E. Willans, Samantha L. Shepherd, Patricia A. Cooper

مصطلحات موضوعية: Cancer Research, 010405 organic chemistry, Cationic polymerization, Cancer, 010402 general chemistry, medicine.disease, 01 natural sciences, Combinatorial chemistry, 0104 chemical sciences, chemistry.chemical_compound, Oncology, chemistry, medicine, Carbene

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525ab33160b9b3d6aefd6bb98ec94c97

المؤلفون: Marcella Sini, Klaus Pors, Omair Sadiq, Marie Wiltshire, Rachel J. Errington, Maria Dolors Pujol, Goreti Ribeiro Morais, Maria Sadiq, Enric Lizano, Laura Cosentino

مصطلحات موضوعية: 0301 basic medicine, Fluorophore, Morpholines, Clinical Biochemistry, Pharmaceutical Science, Anthraquinones, Hydroxylation, Biochemistry, Anthraquinone, Fluorescence, 03 medical and health sciences, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Cell Line, Tumor, Drug Discovery, Humans, Molecular Biology, Fluorescent Dyes, Nemorubicin, biology, Organic Chemistry, CYP1A2, Cytochrome P450, Prodrug, 030104 developmental biology, chemistry, biology.protein, Molecular Medicine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf1749cce0f040b5fb3d6db595563cea

المؤلفون: Simon J. Allison, Samantha L. Shepherd, Ian J. Stratford, Efstathia Baronou, Charlotte E. Willans, Patricia A. Cooper, Ayse Latif, Roger M. Phillips, Christopher Dunnill, Nikolaos T. Georgopoulos, Richard T. Wheelhouse, Steve D. Shnyder, Maria Sadiq

المصدر: Allison, S J, Sadiq, M, Baronou, E, Cooper, P, Dunnill, C, Georgopoulos, N T, Latif, A, Shepherd, S, Shnyder, S D, Stratford, I, Wheelhouse, R, Willans, C & Phillips, R 2017, ' Preclinical anti-cancer activity and multiple mechanisms of action of a cationic silver complex bearing N-heterocyclic carbene ligands. ', Cancer Letters, vol. 403, pp. 98–107 . https://doi.org/10.1016/j.canlet.2017.04.041

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Poly (ADP-Ribose) Polymerase-1, Apoptosis, Q1, 01 natural sciences, Poly (ADP-Ribose) Polymerase Inhibitor, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Topoisomerase II Inhibitors, biology, Chemistry, Imidazoles, Drug Synergism, Cell biology, DNA-Binding Proteins, Dacarbazine, Thioredoxin reductase inhibitor, DNA Topoisomerases, Type I, Oncology, Biochemistry, PARP1 inhibitor, Glycolysis, Topoisomerase inhibitor, Signal Transduction, medicine.drug, Silver-N-heterocycle carbene, Thioredoxin Reductase 1, Cell Survival, DNA damage, medicine.drug_class, DNA repair, Antineoplastic Agents, Poly(ADP-ribose) Polymerase Inhibitors, Inhibitory Concentration 50, 03 medical and health sciences, Antigens, Neoplasm, Cell Line, Tumor, Organometallic Compounds, Temozolomide, medicine, Humans, Cisplatin, Dose-Response Relationship, Drug, 010405 organic chemistry, Topoisomerase, 0104 chemical sciences, Oxidative Stress, DNA Topoisomerases, Type II, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer cell, Glycolytic inhibitor, biology.protein, Topoisomerase I Inhibitors, Topoisomerase-II Inhibitor, Reactive Oxygen Species, DNA Damage

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90fc859b7ede19d1f0f745817361b11c
https://pure.manchester.ac.uk/ws/files/57033841/Preclinical_anti_cancer_activity_and_multiple_mechanisms_of_action_of_a_cationic_silver_complex_bearing_N_heterocyclic_carbene_ligands..pdf