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1
المؤلفون: Stephan A. Ohnmacht, Marialuisa Micco, Aaron G. Dale, Ingrida Pazitna, Mekala Gunaratnam, Anthony P. Reszka, Gavin W. Collie, Stephen Neidle
المصدر: Journal of Medicinal Chemistry. 56:2959-2974
مصطلحات موضوعية: Models, Molecular, Telomerase, Drug Evaluation, Preclinical, Antineoplastic Agents, Naphthalenes, Imides, Ligands, G-quadruplex, chemistry.chemical_compound, Cell Line, Tumor, Drug Discovery, Humans, heterocyclic compounds, Promoter, Telomere, Small molecule, In vitro, G-Quadruplexes, Pancreatic Neoplasms, Biochemistry, chemistry, Cell culture, Drug Design, Molecular Medicine, Drug Screening Assays, Antitumor, DNA
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2
المؤلفون: Mekala Gunaratnam, Vanessa Petrucci, Anthony P. Reszka, Stephan A. Ohnmacht, Marta Carvalho, Marialuisa Micco, Mire Zloh, Stephen Neidle, Alan K. Todd
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:5930-5935
مصطلحات موضوعية: Macrocyclic Compounds, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, G-quadruplex, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Humans, Structure–activity relationship, heterocyclic compounds, HSP90 Heat-Shock Proteins, Promoter Regions, Genetic, Oxazoles, Molecular Biology, Gene, Oxazole, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, DNA, Telomere, Molecular biology, Small molecule, G-Quadruplexes, chemistry, Click chemistry, Molecular Medicine, Selectivity
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3
المؤلفون: Sonja M. Hampel, Rossella Promontorio, Gary N. Parkinson, Marialuisa Micco, Gavin W. Collie, Stephen Neidle
المصدر: Journal of the American Chemical Society. 134:2723-2731
مصطلحات موضوعية: Models, Molecular, Telomerase, Stereochemistry, genetic processes, Antineoplastic Agents, Naphthalenes, Crystallography, X-Ray, Imides, Ligands, G-quadruplex, Biochemistry, Catalysis, Structure-Activity Relationship, chemistry.chemical_compound, Colloid and Surface Chemistry, Cell Line, Tumor, Humans, Structure–activity relationship, heterocyclic compounds, Cell Proliferation, Molecular Structure, Chemistry, RNA, Hydrogen Bonding, DNA, General Chemistry, Telomere, Small molecule, G-Quadruplexes, Folding (chemistry), enzymes and coenzymes (carbohydrates), Drug Screening Assays, Antitumor
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4
المؤلفون: Lee G. D. Fryer, Stephan A. Ohnmacht, Sarah Jurmeister, David E. Neal, Marco Di Antonio, Antonio Ramos-Montoya, Thomas J. Mitchell, Pierre Murat, Marialuisa Micco, Shankar Balasubramanian, Stephen Neidle
المصدر: Biochemistry. 52(8)
مصطلحات موضوعية: Male, Transcriptional Activation, Down-Regulation, Antineoplastic Agents, Biology, Naphthalenes, Imides, Biochemistry, Prostate cancer, Downregulation and upregulation, Transcription (biology), Cell Line, Tumor, medicine, Fluorescence Resonance Energy Transfer, Humans, heterocyclic compounds, Promoter Regions, Genetic, Gene, Nuclear Magnetic Resonance, Biomolecular, Cell Proliferation, Regulation of gene expression, Reporter gene, Circular Dichroism, Prostate, Prostatic Neoplasms, Promoter, medicine.disease, Molecular biology, Androgen receptor, G-Quadruplexes, Gene Expression Regulation, Neoplastic, Receptors, Androgen, Spectrophotometry, Ultraviolet
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5
المؤلفون: Anna Gasperi Campani, Marialuisa Micco, Anna Minarini, Andrea Milelli, Carlo Melchiorre, Laura Roncuzzi, Vincenzo Tumiatti, Maddalena Zini, Daniela Baiocchi, Jessica Marinello, Giovanni Capranico, Claudio Stefanelli
المساهمون: Tumiatti V, Milelli A, Minarini A, Micco M, Gasperi-Campani A, Roncuzzi L, Baiocchi D, Marinello J, Capranico G, Zini M, Stefanelli C, Melchiorre C
المصدر: Journal of medicinal chemistry. 52(23)
مصطلحات موضوعية: NI DERIVATIVE, Stereochemistry, Topoisomerase Inhibitors, Antineoplastic Agents, Naphthalenes, Imides, Chemical synthesis, chemistry.chemical_compound, Diimide, NDI DERIVATIVE, BREAST CANCER, Cell Line, Tumor, Drug Discovery, medicine, Humans, Cytotoxicity, Imide, Protein kinase B, Cell Proliferation, ANTIPROLIFERATIVE ACTIVITY, DNA, In vitro, chemistry, Mechanism of action, Drug Design, Molecular Medicine, Phosphorylation, medicine.symptom, LEUKEMIA
وصف الملف: STAMPA
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6
المؤلفون: Manuela Bartolini, Maria Laura Bolognesi, Marialuisa Micco, Anna Minarini, Carlo Melchiorre, Vincenzo Tumiatti, Vincenza Andrisano, Maurizio Recanatini, Andrea Milelli, Francesca Mancini, Andrea Cavalli, Michela Rosini
المساهمون: V. Tumiatti, A. Milelli, A. Minarini, M. Rosini, M. L. Bolognesi, M. Micco, V. Andrisano, M. Bartolini, F. Mancini, M. Recanatini, A. Cavalli, C. Melchiorre
مصطلحات موضوعية: ACETYLCHOLINESTERASE NONCOVALENT INHIBITORS, Stereochemistry, Ligands, Chemical synthesis, chemistry.chemical_compound, Structure-Activity Relationship, Biological property, Drug Discovery, Polyamines, Imide, chemistry.chemical_classification, Amyloid beta-Peptides, biology, Molecular Structure, PERIPHERAL ANIONIC SITE, Stereoisomerism, MULTI-TARGET-DIRECTED LIGANDS, Acetylcholinesterase, Enzyme, chemistry, ALZHEIMER'S DISEASE, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Cholinesterase Inhibitors, Polyamine, Function (biology), BETA-AMYLOID AGGREGATION
وصف الملف: STAMPA
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a97a8198ad0be8a52cc5d8912b85f7
http://hdl.handle.net/11585/66207 -
7
المؤلفون: David E. Neal, M. Di Antonio, Lee G. D. Fryer, Stephan A. Ohnmacht, Antonio Ramos-Montoya, Thomas J. Mitchell, Marialuisa Micco, Stephen Neidle, Shankar Balasubramanian, Pierre Murat
المصدر: European Urology Supplements. 12:e823-e824
مصطلحات موضوعية: Androgen receptor, Downregulation and upregulation, business.industry, Urology, Cancer research, Castrate-resistant prostate cancer, Medicine, business, G-quadruplex, Alternative treatment
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8
المؤلفون: Marialuisa Micco, Gavin W. Collie, Stephen Neidle, Mekala Gunaratnam, Stephen A. Ohnmacht, Anthony P. Reszka
المصدر: Cancer Research. 72:LB-2
مصطلحات موضوعية: Cancer Research, Telomerase, Cancer, G-quadruplex, medicine.disease, Small molecule, Telomere, chemistry.chemical_compound, Oncology, chemistry, Biochemistry, Cancer cell, medicine, Growth inhibition, Lead compound
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::34c03ac6c2939a60c2b525f133f6b91e
https://doi.org/10.1158/1538-7445.am2012-lb-2 -
9دورية أكاديمية
المؤلفون: Vincenzo Tumiatti, Andrea Milelli, Anna Minarini, Marialuisa Micco, Anna Gasperi Campani, Laura Roncuzzi, Daniela Baiocchi, Jessica Marinello, Giovanni Capranico, Maddalena Zini, Claudio Stefanelli, Carlo Melchiorre
المصدر: Journal of Medicinal Chemistry; Dec2009, Vol. 52 Issue 23, p7873-7877, 5p
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10دورية أكاديمية
المؤلفون: Vincenzo Tumiatti, Andrea Milelli, Anna Minarini, Michela Rosini, Maria Laura Bolognesi, Marialuisa Micco, Vincenza Andrisano, Manuela Bartolini, Francesca Mancini, Maurizio Recanatini, Andrea Cavalli, Carlo Melchiorre
المصدر: Journal of Medicinal Chemistry; Nov2008, Vol. 51 Issue 22, p7308-7312, 5p