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المؤلفون: Prasanthi Geda, Mark A. McCoy, Liping Yang, Chaomin Li, Armetta D. Hill, Xavier Fradera, Marianne L. Spatz, Matthew Ernst Voss, Carolyn Michele Cammarano, Pierre Daublain, Xiao Wang, Christopher F. Thompson, B. Wesley Trotter, C. Gary Marshall, Michael H. Reutershan, Peter Goldenblatt, Latha G. Nair, Manami Shizuka, Tammie C. Yeh, John G. Cryan, Isabelle Dussault, Michelle Martinez, Mingmei Cai, Raymond A. Kemper, Binyuan Sun, Michelle R. Machacek, Dietrich Steinhuebel, Giovanna Scapin, Michael D. Altman, Stephane L. Bogen, Matthew Christopher, Dapeng Chen, Victoria Kutilek, Weidong Pan
المصدر: Journal of Medicinal Chemistry. 64:16213-16241
مصطلحات موضوعية: Chemistry, Clinical investigation, Drug Discovery, P53 protein, Molecular Medicine, Computational biology
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المؤلفون: Michael H, Reutershan, Michelle R, Machacek, Michael D, Altman, Stephane, Bogen, Mingmei, Cai, Carolyn, Cammarano, Dapeng, Chen, Matthew, Christopher, John, Cryan, Pierre, Daublain, Xavier, Fradera, Prasanthi, Geda, Peter, Goldenblatt, Armetta D, Hill, Raymond A, Kemper, Victoria, Kutilek, Chaomin, Li, Michelle, Martinez, Mark, McCoy, Latha, Nair, Weidong, Pan, Christopher F, Thompson, Giovanna, Scapin, Manami, Shizuka, Marianne L, Spatz, Dietrich, Steinhuebel, Binyuan, Sun, Matthew E, Voss, Xiao, Wang, Liping, Yang, Tammie C, Yeh, Isabelle, Dussault, C Gary, Marshall, B Wesley, Trotter
المصدر: Journal of medicinal chemistry. 64(21)
مصطلحات موضوعية: Structure-Activity Relationship, Pyridines, Imidazoles, Humans, Proto-Oncogene Proteins c-mdm2, Tumor Suppressor Protein p53, Protein Binding
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المؤلفون: Marianne L. Spatz, Jean Buteau, Domenico Accili
المصدر: Diabetes. 55(5)
مصطلحات موضوعية: endocrine system, Cell Survival, Endocrinology, Diabetes and Metabolism, Green Fluorescent Proteins, Glucagon-Like Peptides, FOXO1, Mice, Transgenic, Cell Line, Islets of Langerhans, Mice, Glucagon-Like Peptide 1, Internal Medicine, Animals, Insulin, Epidermal growth factor receptor, Transcription factor, Protein kinase B, biology, Cell growth, Forkhead Box Protein O1, Forkhead Transcription Factors, Glucagon, Peptide Fragments, Glucose, Cancer research, biology.protein, FOXA2, Beta cell, Chromatin immunoprecipitation, hormones, hormone substitutes, and hormone antagonists, Cell Division
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المؤلفون: Philip E. Brandish, Erica Leccese, Marianne L. Spatz, François G. Gervais, John H. Shin, Alexandra Hicks, Jie Zhang-Hoover
المصدر: Journal of Pharmacological and Toxicological Methods. :61-67
مصطلحات موضوعية: Agonist, medicine.drug_class, B-cell receptor, Syk, chemical and pharmacologic phenomena, Biology, Pharmacology, Toxicology, Lymphocyte Activation, PI3Kδ, Flow cytometry, Structure-Activity Relationship, TLR9, immune system diseases, hemic and lymphatic diseases, medicine, Methods, Bruton's tyrosine kinase, Animals, SYK, Protein Kinase Inhibitors, B cell, Whole blood, CD86, B-Lymphocytes, medicine.diagnostic_test, Dose-Response Relationship, Drug, hemic and immune systems, Rats, Synergy, medicine.anatomical_structure, Blood, Rats, Inbred Lew, BTK, Dextran-coupled anti-IgD, biology.protein, Rat, Female
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3287ccf8ff1d5ae9339a10b476604f85