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المؤلفون: Daria Darczak, Rachel Davis-Taber, Michael F. Jarvis, Victoria E. Scott, Marie E. Uchic, Xenia Beebe, Andrew O. Stewart
المصدر: Bioorganic & Medicinal Chemistry Letters. 18:2162-2166
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, endocrine system diseases, Stereochemistry, education, Clinical Biochemistry, Pharmaceutical Science, Adenylate kinase, Receptor type, Hydrazide, Biochemistry, Cyclase, Radioligand Assay, Structure-Activity Relationship, chemistry.chemical_compound, health services administration, Drug Discovery, Humans, Molecular Biology, Cells, Cultured, Peptide ligand, G protein-coupled receptor, Molecular Structure, Organic Chemistry, food and beverages, Small molecule, humanities, Hydrazines, chemistry, Pituitary Adenylate Cyclase-Activating Polypeptide, Molecular Medicine, Calcium, Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I
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المؤلفون: Paul L. Richardson, Victoria E. Scott, Marie E. Uchic, Larry Solomon, Edward T. Olejniczak, Karl A. Walter, Rachel Davis-Taber, Danying Song, Chaohong Sun, Leo W. Barrett, Ana Pereda-Lopez, Philip J. Hajduk, Marc R. Lake
المصدر: Proceedings of the National Academy of Sciences. 104:7875-7880
مصطلحات موضوعية: Molecular Sequence Data, Vasoactive intestinal peptide, Peptide binding, Peptide, Biology, Receptors, Corticotropin-Releasing Hormone, Protein Structure, Secondary, Mice, Extracellular, Animals, Humans, Amino Acid Sequence, Receptor, Peptide sequence, chemistry.chemical_classification, Multidisciplinary, C-terminus, Biological Sciences, Protein Structure, Tertiary, Cell biology, Solutions, N-terminus, Biochemistry, chemistry, Mutation, Pituitary Adenylate Cyclase-Activating Polypeptide, Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c62621b818f70dc9bd76d1e57a970e
https://doi.org/10.1073/pnas.0611397104 -
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المؤلفون: Brenda Martino, Diana L. Donnelly-Roberts, Jill M. Wetter, Marie E. Uchic, Kennan C. Marsh, Ahmed A. Hakeem, Sherry Nelson, Teodozyj Kolasa, Gin C. Hsieh, Odile F. El-Kouhen, Kathleen H. Mortell, Rohde Jeffrey J, Meena V. Patel, Ruth L. Martin, Marlon D. Cowart, Peter R. Hollingsworth, Marc A. Terranova, Andrew O. Stewart, Robert B. Moreland, and Jorge D. Brioni, Mark A. Matulenko, Loan N. Miller, Gary A. Gintant, James P. Sullivan, Marian T. Namovic, John F. Darbyshire, Renjie Chang, Masaki Nakane
المصدر: Journal of Medicinal Chemistry. 49:7450-7465
مصطلحات موضوعية: Male, Agonist, ERG1 Potassium Channel, Patch-Clamp Techniques, medicine.drug_class, Stereochemistry, Action Potentials, Administration, Oral, Biological Availability, In Vitro Techniques, Pharmacology, Partial agonist, Cell Line, Cyclic N-Oxides, Purkinje Fibers, Structure-Activity Relationship, chemistry.chemical_compound, Dogs, Erectile Dysfunction, In vivo, Oral administration, Drug Discovery, medicine, Animals, Humans, Benzamide, Receptors, Dopamine D4, Haplorhini, Ether-A-Go-Go Potassium Channels, Rats, Bioavailability, Piperazine, chemistry, Benzamides, ABT-670, Molecular Medicine
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المؤلفون: Scott J. Baker, Loan N. Miller, Meena V. Patel, Marie E. Uchic, Kennan C. Marsh, Prisca Honore, Renjie Chang, Odile F. El Kouhen, Guo Zhu Zheng, Pramila Bhatia, Jorge D. Brioni, Robert B. Moreland, Sonya G. Lehto, Jill M. Wetter, Andrew O. Stewart, Teodozyj Kolasa
المصدر: Bioorganic & Medicinal Chemistry Letters. 16:4936-4940
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Analgesic, Pain, Pharmaceutical Science, Pharmacology, Receptors, Metabotropic Glutamate, Blood–brain barrier, Biochemistry, Cell Line, Structure-Activity Relationship, In vivo, Drug Discovery, medicine, Animals, Humans, Molecular Biology, Neurons, Aza Compounds, Molecular Structure, Chemistry, Organic Chemistry, Glutamate receptor, Antagonist, Brain, Rats, medicine.anatomical_structure, Metabotropic receptor, Models, Animal, Neuropathic pain, Molecular Medicine, Metabotropic glutamate receptor 1
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المؤلفون: Meena V. Patel, Marie E. Uchic, Marie P. Honore, Jerome F. Daanen, Loan N. Miller, Renjie Chang, Andrew O. Stewart, Masaki Nakane, Steven P. Latshaw, Pramila Bhatia, Sonya G. Lehto, Teodozyj Kolasa, Odile F. El Kouhen, Jorge D. Brioni, Robert B. Moreland, Guo Zhu Zheng
المصدر: Journal of Medicinal Chemistry. 48:7374-7388
مصطلحات موضوعية: Male, Stereochemistry, Receptor, Metabotropic Glutamate 5, Allosteric regulation, Pharmacology, Receptors, Metabotropic Glutamate, Cell Line, Rats, Sprague-Dawley, Radioligand Assay, Structure-Activity Relationship, In vivo, Cerebellum, Drug Discovery, Animals, Humans, Structure–activity relationship, Receptor, IC50, Pain Measurement, Analgesics, Aza Compounds, Fluorenes, Chemistry, Antagonist, In vitro, Rats, Molecular Medicine, Metabotropic glutamate receptor 1, Calcium, Heterocyclic Compounds, 3-Ring
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المؤلفون: Masaki Nakane, Bryan F. Cox, Robert B. Moreland, Jorge D. Brioni, Mark A. Osinski, Terese Seifert, Marie E. Uchic, Loan N. Miller, Thomas K. Shaughnessy
المصدر: Pharmacology Biochemistry and Behavior. 81:211-219
مصطلحات موضوعية: Pharmacology, Agonist, medicine.medical_specialty, medicine.drug_class, Clinical Biochemistry, Biology, Toxicology, Biochemistry, Behavioral Neuroscience, Dopamine receptor D1, Endocrinology, Dopamine receptor, Dopamine, Dopamine receptor D2, Internal medicine, Calcium flux, medicine, Receptor, Biological Psychiatry, Endogenous agonist, medicine.drug
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المؤلفون: Renjie Chang, Marc A. Terranova, Masaki Nakane, Andrew O. Stewart, Leimin Fan, Marian T. Namovic, Loan N. Miller, Robert B. Moreland, Teodozyi Kolasa, Diana L. Donnelly-Roberts, Bruce Surber, Marie E. Uchic, Jorge D. Brioni, Mark A. Matulenko
المصدر: Bioorganic & Medicinal Chemistry Letters. 14:5095-5098
مصطلحات موضوعية: Agonist, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, In Vitro Techniques, Ligands, Tritium, Biochemistry, Chemical synthesis, Piperazines, Cell Line, Radioligand Assay, Structure-Activity Relationship, chemistry.chemical_compound, Dopamine, Acetamides, Drug Discovery, medicine, Radioligand, Humans, Structure–activity relationship, heterocyclic compounds, Molecular Biology, Receptors, Dopamine D2, Chemistry, Receptors, Dopamine D4, Organic Chemistry, Piperazine, Molecular Medicine, Acetamide, medicine.drug
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المؤلفون: Earl J. Gubbins, Loan N. Miller, Marc A. Terranova, Robert B. Moreland, Jeffrey N. Masters, Odile F. El-Kouhen, Diana L. Donnelly-Roberts, Marie E. Uchic, Jorge D. Brioni, Marian T. Namovic, Rosalind J. Helfrich, Renjie Chang, Masaki Nakane
المصدر: Biochemical Pharmacology. 68:761-772
مصطلحات موضوعية: Agonist, medicine.drug_class, Dopamine, Recombinant Fusion Proteins, CHO Cells, Pharmacology, Biochemistry, Dopamine agonist, Partial agonist, Cell Line, Cricetinae, Calcium flux, medicine, Animals, Humans, Receptor, Cells, Cultured, Receptors, Dopamine D2, Chemistry, Receptors, Dopamine D4, Receptors, Dopamine D3, Biological Transport, GTP-Binding Protein alpha Subunits, HYDIA, Apomorphine, Calcium, Endogenous agonist, medicine.drug
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المؤلفون: Renjie Chang, Marie E. Uchic, Jorge D. Brioni, Bruce W. Surber, Andrew O. Stewart, Marc A. Terranova, Robert B. Moreland, Mark A. Matulenko
المصدر: European Journal of Pharmacology. 497:147-154
مصطلحات موضوعية: Agonist, medicine.drug_class, CHO Cells, Pharmacology, Biology, Ligands, Tritium, Dopamine agonist, Piperazines, Cell Line, Radioligand Assay, Dopamine receptor D1, Dopamine, Cricetinae, Acetamides, Dopamine receptor D5, medicine, Radioligand, Animals, Humans, Dose-Response Relationship, Drug, Receptors, Dopamine D2, Receptors, Dopamine D4, Rats, Apomorphine, Dopamine Agonists, Endogenous agonist, medicine.drug
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المؤلفون: Michael F. Jarvis, Kevin J. Lynch, Connie R. Faltynek, Torben R. Neelands, Marie E Uchic, Wende Niforatos, Heath A. McDonald, Edward C. Burgard
المصدر: British Journal of Pharmacology. 140:202-210
مصطلحات موضوعية: Pharmacology, Agonist, medicine.drug_class, Biology, Cell biology, body regions, Competitive antagonist, Homologous desensitization, medicine, Enzyme-linked receptor, Homomeric, Receptor, Ion channel linked receptors, G protein-coupled receptor